TAVI Is a Reasonable Option for High-Risk Elderly Patients

Transcatheter aortic valve implantation benefits patients with severe symptomatic aortic stenosis

THURSDAY, May 3 (HealthDay News) -- For high-risk elderly patients with aortic stenosis, transcatheter aortic-valve implantation (TAVI) is a reasonable option, according to a study published in the May 3 issue of the New England Journal of Medicine.

Martine Gilard, M.D., Ph.D., from the Centre Hospitalier Universitaire Brest in France, and colleagues reported the results of a prospective multicenter study involving 3,195 elderly patients (mean age, 82.7 years) who underwent TAVI in France between January 2010 and October 2011. All participants were highly symptomatic and had a high surgical risk for aortic-valve replacement.

The investigators note that Edwards SAPIEN devices were implanted into 66.9 percent of patients and Medtronic CoreValve devices in 33.1 percent; they observed a success rate of 96.9 percent for the procedure. The approaches were transapical (17.8 percent), or transarterial (transfemoral, 74.6 percent; subclavian, 5.8 percent; or other, 1.8 percent). The rates of 30-day and one-year mortality were 9.7 and 24 percent, respectively. The incidence of stroke and periprosthetic aortic regurgitation at one-year was 4.1 and 64.5 percent, respectively. A higher logistic risk score on the European System for Cardiac Operative Risk Evaluation, New York Heart Association functional class III or IV symptoms, a transapical approach, and a higher amount of periprosthetic regurgitation correlated significantly with decreased survival in a multivariate model.

"TAVI is a new therapeutic option for high-risk patients with severe aortic stenosis," the authors write. "Further progress in patient-selection criteria, postprocedural care, and choice of optimal access are essential for improving results."

The study was funded by Edwards Lifesciences and Medtronic; several authors disclosed financial ties to these and other medical device companies.

Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

What internal motivators drive RNs to pursue a BSN?
Nursing2014 , October 2014
Free access will expire on November 24, 2014.


Breast Cancer Risk Assessment in Primary Care
MCN, The American Journal of Maternal/Child Nursing, September/October 2014
Free access will expire on November 10, 2014.


Nurses spurring innovation
Nursing Management, October 2014
Free access will expire on November 10, 2014.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events