View Entire Collection
By Clinical Topic
By State Requirement
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
THURSDAY, May 3 (HealthDay News) -- A Western-style diet is associated with increased levels of endotoxin activity (endotoxemia), and a prudent-style diet (containing moderately greater amounts of omega-3 fatty acids, vitamin C, and vitamin E than the Western-style diet) is linked to reduced endotoxemia, according to a study published in the May issue of Gastroenterology.
Noting that endotoxemia is associated with systemic inflammation and metabolic syndrome, Swaroop Pendyala, M.D., from The Rockefeller University in New York City, and colleagues investigated the impact of diet on endotoxemia. In a crossover study, eight healthy individuals were fed a Western-style and a prudent-style diet with similar caloric density for one month. Using a neutrophil priming method that detects lipopolysaccharide from gram-negative organisms, blood endotoxin levels were measured.
The researchers observed a 71 percent increase in endotoxemia induced by the Western-style diet, compared with a 31 percent decrease with the prudent diet.
"The Western-style diet might, therefore, contribute to endotoxemia by causing changes in gastrointestinal barrier function or the composition of the microbiota," the authors write. "Therapeutic reagents that reduce endotoxemia might reduce systemic inflammation in patients with gastrointestinal diseases or metabolic syndrome."
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top