Living Close to Major Roadway at Time of MI Ups Mortality

Acute myocardial infarction survivors have increased risk of all-cause mortality over 10 years

TUESDAY, May 8 (HealthDay News) -- For survivors of acute myocardial infarction (AMI), residential proximity to a major roadway at the time of AMI is linked to an increased risk of 10-year mortality, according to a study published in the May 8 issue of Circulation.

Joshua I. Rosenbloom, M.P.H., from Harvard Medical School in Boston, and colleagues analyzed data from 3,547 patients hospitalized for AMI who participated in the Determinants of Myocardial Infarction Onset Study. Addresses were geocoded and the distance to the nearest major roadway was noted.

After 10 years of follow-up, the researchers identified 1,071 deaths. After adjusting for personal, clinical, and neighborhood-level variables, compared with living >1,000 m from a major roadway, there was an increased risk of all-cause mortality associated with living ≤100 m (hazard ratio [HR], 1.27; 95 percent confidence interval [CI], 1.01 to 1.60), 100 to ≤200 m (HR, 1.19; 95 percent CI, 0.93 to 1.60), and 200 to ≤1,000 m (HR, 1.13; 95 percent CI, 0.99 to 1.30) from a major roadway (Ptrend = 0.015).

"In this multicenter study, living close to a major roadway at the time of AMI was associated with increased risk of all-cause 10-year mortality; this relationship persisted after adjustment for individual and neighborhood-level covariates," the authors write.

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