Solvent Exposure Tied to Lower Cognition Among Less Educated

Dose-response association seen between lifetime exposure and relative risk of poor cognition

TUESDAY, May 29 (HealthDay News) -- Occupational exposure to chemical solvents affects the cognitive abilities of less-educated workers, but not more-educated workers, with a dose-response relationship between lifetime exposure and the risk of poor cognition, according to a study published in the May 29 issue of Neurology.

Erika L. Sabbath, Sc.D., from Harvard University in Boston, and colleagues analyzed data from a prospective cohort of 4,134 French national gas and electricity employees. A validated job-exposure matrix was used to assess lifetime exposure to chlorinated solvents, petroleum solvents, benzene, and non-benzene aromatic solvents. Education was classified as less than secondary-education or above secondary education, and was considered a proxy for cognitive reserve. Scoring below the 25th percentile on the Digit Symbol Substitution Test was used to define cognitive impairment.

The researchers found that less-educated patients had higher solvent exposure rates, with a dose-response relationship between lifetime exposure to each solvent type and an increased relative risk for poor cognition (e.g., high exposure to benzene: relative risk, 1.24). Significant trends were seen for three of the four solvents. Among less-educated patients, the recency of solvent exposure also predicted worse cognition. Among those participants with secondary education or higher, quantification of solvent exposure was not significantly associated with cognition.

"Solvent exposure is associated with poor cognition only among less-educated individuals," the authors write. "Higher cognitive reserve in the more-educated group may explain this finding."

Abstract
Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95


The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95


Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.


Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.


Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events