Low Risk of Herpes Zoster Recurrence in Elderly

Short-term risk of herpes zoster recurrence low, regardless of vaccination status

WEDNESDAY, June 6 (HealthDay News) -- For older immunocompetent adults, the risk of herpes zoster recurrence following a recent initial episode is fairly low in both vaccinated and unvaccinated cohorts, according to a study published online June 4 in the Journal of Infectious Diseases.

Hung Fu Tseng, Ph.D., M.P.H., from Southern California Kaiser Permanente in Pasadena, and colleagues compared the incidence of recurrent herpes zoster between vaccinated (1,036 individuals) and unvaccinated (5,180 individuals) matched cohorts of immunocompetent elderly adults (aged ≥60 years) with a recent episode of herpes zoster.

The researchers found that, for adults younger than 70 years, the incidence of recurrent herpes zoster was 0.99 per 1,000 person-years in the vaccinated cohort and 2.20 per 1,000 person-years in the unvaccinated cohort. The adjusted hazard ratio was 0.39 (95 percent confidence interval [CI], 0.05 to 4.45) for those aged younger than 70 years and 1.05 (95 percent CI, 0.30 to 3.69) among those aged 70 years or older.

"Our data suggest that the short-term risk of herpes zoster recurrence following a recent initial episode is fairly low among immunocompetent adults, regardless of vaccination status," the authors write. "While there was a trend towards lower rates in individuals vaccinated with zoster vaccine, especially in those younger than 70 years old, the rarity of outcome limited our ability to make definitive statements about the effect of vaccination."

One of the authors received funding from Merck.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

What internal motivators drive RNs to pursue a BSN?
Nursing2014 , October 2014
Free access will expire on November 24, 2014.


Breast Cancer Risk Assessment in Primary Care
MCN, The American Journal of Maternal/Child Nursing, September/October 2014
Free access will expire on November 10, 2014.


Nurses spurring innovation
Nursing Management, October 2014
Free access will expire on November 10, 2014.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events