Many Psoriasis Patients Undertreated for CV Risk Factors

Proportion of patients with moderate to severe psoriasis at treatment goal for risk factors not ideal

THURSDAY, June 21 (HealthDay News) -- A large proportion of patients with moderate-to-severe plaque psoriasis are underdiagnosed and undertreated for cardiovascular (CV) risk factors, according to a study published in the July issue of the Journal of the American Academy of Dermatology.

Alexa B. Kimball, M.D., from Harvard Medical School in Boston, and colleagues reviewed the medical histories, including glucose, lipid, and blood pressure levels, of 2,899 patients with moderate-to-severe psoriasis participating in three phase III ustekinumab trials.

The researchers found that there were significant risk factors in patients with moderate-to-severe psoriasis, with 58.6 and 28.8 percent of patients, respectively, having two or more and three or more CV risk factors. The risk of CV events, based on Framingham risk score, was high for 18.6 percent of patients and intermediate for 12.3 percent of patients. A small proportion of patients with diabetes, hypertension, or hyperlipidemia were undiagnosed at baseline (2.3, 9.1, and 4.9 percent, respectively). A higher proportion were untreated at baseline (19.1, 21.8, and 38.6 percent, respectively), and the proportion achieving the treatment goal was not ideal (36.7, 59.6, and 69.7 percent, respectively).

"In summary, study findings highlight the fact that despite a growing recognition of the association between psoriasis and CV risk, a high proportion of patients with psoriasis severe enough to qualify for clinical trial participation have unrecognized or inadequately treated CV risk factors," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95

The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95

Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95

More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.

Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.

Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.

More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events