View Entire Collection
By Clinical Topic
By State Requirement
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
WEDNESDAY, June 27 (HealthDay News) -- Prenatal exposure to butylbenzyl phthalate (BBzP), as assessed by increased concentrations of monobenzyl phthalate (MBzP) in the urine, is associated with an increased risk of early-onset eczema in offspring, according to a study published online June 26 in Environmental Health Perspectives.
Allan C. Just, Ph.D., from Columbia University in New York City, and colleagues measured MBzP in the urine of 407 African-American and Dominican women during the third trimester of pregnancy. The women were later asked whether their child had ever been diagnosed with eczema, and blood samples from the children were examined for allergens at age 24, 36, and 60 months.
The researchers found that over 99 percent of urine samples contained MBzP. At 24 months, 30 percent of children had developed eczema, although eczema was much more common in African-Americans than Dominicans (48 versus 21 percent). After adjusting for urine-specific gravity, sex, and race/ethnicity, increasing MBzP levels were associated with an increased risk of developing early-onset eczema by 24 months (relative risk, 1.52 for an interquartile range increase in log MBzP concentration). The association was not affected by seroatopy, and MBzP did not correlate with allergic sensitization.
"Prenatal exposure to BBzP may influence the risk of developing eczema in early childhood," Just and colleagues conclude. "The association appeared to be primarily among those with early-onset eczema, reported by 24 months of age."
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top