Emergency Service Hospital Prenotification Ups Stroke Tx

Prenotification improves timing of tPA administration, proportion of patients receiving tPA

TUESDAY, July 10 (HealthDay News) -- Emergency medical service (EMS) hospital prenotification results in more timely imaging and administration of tissue plasminogen activator (tPA) and an increased proportion of eligible patients with acute ischemic stroke receiving tPA, according to a study published online July 10 in Circulation: Cardiovascular Quality and Outcomes.

Cheryl B. Lin, from the Duke-National University of Singapore Graduate Medical School, and colleagues examined 371,988 patients with acute ischemic stroke who were transported by EMS and enrolled in Get With The Guidelines-Stroke from April 2003 through March 2011.

The researchers found that hospital prenotification occurred for 67.0 percent of EMS-transported patients. Patients with EMS prenotification who arrived within two hours were significantly more likely to be treated with tPA within three hours. Significantly shorter door-to-imaging times (26 versus 31 minutes), door-to-needle times (78 versus 80 minutes), and symptom onset-to-needle times (141 versus 145 minutes) were seen for those with EMS prenotification. Based on multivariate analysis that accounted for clustering of patients within hospitals, use of EMS prenotification was independently associated with increased likelihood of door-to-imaging times ≤25 minutes, door-to-needle times for tPA ≤60 minutes, onset-to-needle times ≤120 minutes, and tPA use within three hours.

"These findings support the need for initiatives targeted at improving EMS prenotification rates nationally as a mechanism for improving acute ischemic stroke quality of care and outcomes," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95

The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95

Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95

More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.

Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.

Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.

More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events