Factors Impacting Quality of Life at End of Life Identified

Nine factors explain some of the variance in quality of life for patients with advanced cancer

TUESDAY, July 10 (HealthDay News) -- Nine factors explain some of the variance in the quality of life (QOL) of patients with advanced cancer in end-of-life (EOL) care, according to a study published online July 9 in the Archives of Internal Medicine.

To identify the main factors that influence QOL at EOL, Baohui Zhang, of the Dana-Farber Cancer Institute in Boston, and associates conducted a multisite, prospective, longitudinal study involving 396 patients with advanced cancer and their informal caregivers. Participants were followed from enrollment in September 2002 through February 2008 to death, a median of 4.1 months later.

While the majority of variance in QOL at EOL was unexplained, the researchers identified a set of nine factors that explained some of the variance. Factors that had a negative effect on QOL included: intensive care unit stays, which explained 4.4 percent of the variance; hospital deaths (2.7 percent); patient worry at baseline (2.7 percent); feeding tube use in the final week (1.1 percent); and chemotherapy in the final week (0.8 percent). The following factors had a positive impact on QOL: religious prayer or meditation at baseline (2.5 percent); pastoral care (1.0 percent); and patient-physician therapeutic alliance at baseline (0.7 percent). The site of cancer care explained 1.8 percent of the variance in QOL.

"By reducing patient worry, encouraging contemplation, integrating pastoral care within medical care, fostering a therapeutic alliance between patient and physician that enables patients to feel dignified, and preventing unnecessary hospitalizations and receipt of life-prolonging care, physicians can enable their patients to live their last days with the highest possible level of comfort and care," the authors write.

Full Text

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Debunking Three Rape Myths
Journal of Forensic Nursing, October/December 2014
Expires: 12/31/2016 CE:2.5 $24.95

Drug updates and approvals: 2014 in review
The Nurse Practitioner, 13December 2014
Expires: 12/31/2016 CE:3 $27.95

Can Food Processing Enhance Cancer Protection?
Nutrition Today, September/October 2014
Expires: 10/31/2016 CE:2 $21.95

More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events