Bariatric Surgery Cuts MI Incidence in Obese With T2DM

No effect on stroke incidence seen for obese with type 2 diabetes undergoing bariatric surgery

WEDNESDAY, Aug. 8 (HealthDay News) -- For obese individuals with type 2 diabetes, bariatric surgery reduces the incidence of some cardiovascular events, specifically myocardial infarction, according to a study published online Aug. 1 in Diabetes Care.

Stefano Romeo, M.D., Ph.D., from the University of Gothenburg in Sweden, and colleagues examined the effect of bariatric surgery on cardiovascular events using data from participants in the Swedish Obese Subjects (SOS) study with type 2 diabetes. Participants, 345 individuals in the surgery group and 262 controls, were followed for a mean of 13.3 years for all cardiovascular events.

The researchers found that bariatric surgery correlated with a significantly reduced incidence of myocardial infarction (38 events in the surgery group versus 43 in the control group; adjusted hazard ratio (HR), 0.56). Bariatric surgery had no significant effect on stroke incidence (34 events in the surgery group versus 24 events in the control group; log-rank P = 0.852; adjusted HR, 0.73; P = 0.29). The bariatric surgery-associated reduction in myocardial infarction was stronger in individuals with higher serum total cholesterol and triglycerides at baseline (interaction P value = 0.02 for both traits). Body mass index had no effect on surgery outcome.

"In conclusion, this is the first prospective study showing that bariatric surgery is associated with reduced incidence of myocardial infarction in obese individuals with type 2 diabetes," the authors write. "It also provides support for the recommendations of the international guidelines regarding bariatric surgery in obese individuals with type 2 diabetes."

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