Antihypertensive Use in Pregnancy Increasing

Prevalence close to 5 percent; some medications contraindicated in pregnancy are still used

MONDAY, Sept. 10 (HealthDay News) -- The prevalence of antihypertensive use in pregnancy is approaching 5 percent and is increasing, according to a study published online Sept. 10 in Hypertension.

Brian T. Bateman, M.D., from Brigham and Women's Hospital in Boston, and colleagues analyzed maternal exposure to antihypertensive medications using data from Medicaid pharmacy claim files from 2000 to 2007, creating a cohort of 1,106,757 Medicaid patients.

Of the participants, 4.4 percent (48,453 women) were exposed to antihypertensive medications during pregnancy. The researchers found that during the study period the prevalence of antihypertensive use increased from 3.5 to 4.9 percent. Compared to nonusers, users of antihypertensive medications were older, more likely to be white or black, and more likely to have comorbid diabetes mellitus and renal disease. Exposure to antihypertensives was noted for 1.9 percent of pregnant women during the first trimester, 1.7 percent during the second trimester, and 3.2 percent during the third trimester. Patients were exposed to a wide range of antihypertensive medications. Angiotensin-converting enzyme inhibitors, which are contraindicated in late pregnancy, were used by 4.9 percent of users in the second trimester and 1.1 percent in the third trimester.

"Our data suggest that the exposure to antihypertensive medications in pregnancy is relatively common and increasing," the authors write. "Research investigating the comparative safety and efficacy of antihypertensive therapy in pregnancy is urgently needed to define the optimal approach to therapy."

Abstract
Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95


The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95


Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.


Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.


Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events