Screening for Type 2 Diabetes Not Linked to Drop in Mortality

Screening patients at increased risk not linked to decrease in CVD-, cancer-, diabetes-linked death

THURSDAY, Oct. 4 (HealthDay News) -- For middle-aged adults at high risk of type 2 diabetes, invitation to screening is not associated with a decrease in mortality, according to a study published online Oct. 4 in The Lancet.

Rebecca K. Simmons, Ph.D., from the MRC Epidemiology Unit in Cambridge, U.K., and colleagues assessed the effect of a population-based stepwise screening program on mortality in a parallel group cluster-randomized trial involving 33 general practices in eastern England. Fifteen practices were assigned to screening followed by intensive multifactorial treatment for those diagnosed with diabetes; 13 were assigned to screening plus routine care of diabetes; and five practices made up a no-screening control group. A total of 20,184 adults, aged 40 to 69 years, at high risk of prevalence of undiagnosed diabetes constituted the study population.

The researchers found that 94 percent of the 16,047 high-risk individuals in screening practices were invited for screening, 73 percent attended, and 3 percent were diagnosed with diabetes. During a median of 9.6 years of follow-up there were 1,532 deaths in the screening practices and 377 in control practices, for a hazard ratio for death of 1.06 (95 percent confidence interval, 0.90 to 1.25). Invitation to screening was not associated with a significant reduction in cardiovascular-, cancer-, or diabetes-related mortality.

"In conclusion, invitation to a single round of screening for type 2 diabetes in high-risk individuals in U.K. general practice might benefit the minority with detectable disease but was not associated with a reduction in all-cause or diabetes-related mortality over 10 years," the authors write.

The study was partially funded by Bio-Rad. Two authors disclosed financial ties to Ely Lilly and/or Novo Nordisk.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95

The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95

Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95

More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.

Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.

Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.

More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events