View Entire Collection
By Clinical Topic
By State Requirement
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
TUESDAY, Oct. 9 (HealthDay News) -- There is a moderate but significant transient increased risk in bleeding following vigorous physical activity in children and adolescent boys with hemophilia, according to a study published in the Oct. 10 issue of the Journal of the American Medical Association.
Carolyn R. Broderick, M.B.B.S., from the University of Sydney in Australia, and colleagues conducted a case-crossover study involving 104 children and adolescent boys aged 4 through 18 years with moderate or severe hemophilia A or B participating in a multicenter prospective cohort. Patients were monitored for one year and, following each bleed, the child or parent was interviewed to ascertain physical activity exposure.
The researchers found that, over the follow-up period, 436 bleeds occurred. The bleeds used in the primary risk analysis were 336 bleeds that occurred more than two weeks after the preceding bleed. Category 2 activities (such as basketball) were associated with a significant transient increase in the risk of bleeding (odds ratio, 2.7) compared to inactivity or category 1 activities (such as swimming). There was a greater significant transient increase in risk (odds ratio, 3.7) associated with category 3 activities (such as wresting). For a child who participates in an average of category 2 activities twice weekly and category 3 activities once weekly and who bleeds five times per year, these activities were associated with only one of the annual bleeds. Bleeding incidence was significantly lower (2 percent; P = 0.004) for every 1 percent increase in clotting factor level.
"In children and adolescents with hemophilia, vigorous physical activity was transiently associated with a moderate relative increase in risk of bleeding," the authors write.
Several authors disclosed financial ties to the pharmaceutical and health care industries.
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top