View Entire Collection
By Clinical Topic
By State Requirement
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
TUESDAY, Oct. 30 (HealthDay News) -- A single high-fat meal has detrimental effects on vascular function, according to a study presented at the annual Canadian Cardiovascular Congress, held from Oct. 27 to 31 in Toronto.
Vincent Lee, from the University of Calgary in Canada, and colleagues examined the effect of a single high-fat commercial breakfast meal (900 calories; 50 g fat) on microvascular function (as assessed by hyperemic velocity time integral) and macrovascular function (as assessed by flow-mediated dilation) in 20 healthy, young (mean age, 22.9 years) non-smoking subjects without cardiovascular disease. Micro- and macrovascular function were assessed after consumption of the high-fat meal (meal day) and on a control day without the high-fat meal.
The researchers found that, after consumption of the high-fat meal, microvascular function significantly declined by 15 to 20 percent after two hours; this change was significantly different from measures conducted on the control day. In contrast, there was no significant change in macrovascular function on the meal day or control day.
"Our results suggest that a single high-fat meal affects the microvascular bed, impairing velocity time integral, but not flow-mediated dilation," Lee and colleagues conclude. "This suggests that the association between a high-fat diet and atherosclerosis may be due to impairment of the microvascular bed, an impact that can be seen in an acute time frame."
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top