Short Sleep Duration Found Not to Lead to Insulin Resistance

But, less sleep may predispose to overeating by different mechanisms in men and women

FRIDAY, Nov. 2 (HealthDay News) -- Short sleep durations do not lead to increased insulin resistance, according to a study published in the Nov. 1 issue of SLEEP.

Marie-Pierre St-Onge, Ph.D., from St. Luke's/Roosevelt Hospital in New York City, and colleagues conducted a randomized crossover study in which 27 normal-weight 30- to 45-year-old adults who habitually slept seven to nine hours a night were studied under a short (four hours in bed) or habitual (nine hours in bed) sleep condition. For each four-day study period, a controlled diet was provided and fasting blood samples were obtained daily.

The researchers found that body weights were significantly reduced by 2.2 ± 0.4 lbs and 1.7 ± 0.4 lbs during the habitual and short-sleep phases, respectively. Sleep duration had no effect on glucose, insulin, and leptin profiles. There were sex differences in ghrelin and glucagon-like peptide 1 (GLP-1) responses. Fasting (P = 0.054) and morning (08:00 to 12:00) (P = 0.042) total ghrelin increased during the short-sleep phase in men but not women. For GLP-1, the reverse was seen, with afternoon levels (12:30 to 19:00) lower (P = 0.016) in women but not men after short-sleep periods compared with habitual sleep.

"These data suggest that, in the context of negative energy balance, short sleep does not lead to a state of increased insulin resistance, but may predispose to overeating via separate mechanisms in men and women," the authors write.

Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events