Short Sleep Duration Found Not to Lead to Insulin Resistance

But, less sleep may predispose to overeating by different mechanisms in men and women

FRIDAY, Nov. 2 (HealthDay News) -- Short sleep durations do not lead to increased insulin resistance, according to a study published in the Nov. 1 issue of SLEEP.

Marie-Pierre St-Onge, Ph.D., from St. Luke's/Roosevelt Hospital in New York City, and colleagues conducted a randomized crossover study in which 27 normal-weight 30- to 45-year-old adults who habitually slept seven to nine hours a night were studied under a short (four hours in bed) or habitual (nine hours in bed) sleep condition. For each four-day study period, a controlled diet was provided and fasting blood samples were obtained daily.

The researchers found that body weights were significantly reduced by 2.2 ± 0.4 lbs and 1.7 ± 0.4 lbs during the habitual and short-sleep phases, respectively. Sleep duration had no effect on glucose, insulin, and leptin profiles. There were sex differences in ghrelin and glucagon-like peptide 1 (GLP-1) responses. Fasting (P = 0.054) and morning (08:00 to 12:00) (P = 0.042) total ghrelin increased during the short-sleep phase in men but not women. For GLP-1, the reverse was seen, with afternoon levels (12:30 to 19:00) lower (P = 0.016) in women but not men after short-sleep periods compared with habitual sleep.

"These data suggest that, in the context of negative energy balance, short sleep does not lead to a state of increased insulin resistance, but may predispose to overeating via separate mechanisms in men and women," the authors write.

Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Debunking Three Rape Myths
Journal of Forensic Nursing, October/December 2014
Expires: 12/31/2016 CE:2.5 $24.95

Drug updates and approvals: 2014 in review
The Nurse Practitioner, 13December 2014
Expires: 12/31/2016 CE:3 $27.95

Can Food Processing Enhance Cancer Protection?
Nutrition Today, September/October 2014
Expires: 10/31/2016 CE:2 $21.95

More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events