Third MMR Vaccine Dose Can Curtail Mumps Outbreak

In community with a large mumps outbreak, third MMR dose reduced attack rate by 75 percent

MONDAY, Nov. 5 (HealthDay News) -- Administering a third dose of the measles-mumps-rubella (MMR) vaccine reduced the village-wide attack rate by about 75 percent in a community experiencing a large mumps outbreak despite a high rate of previous MMR vaccination, according to research published online Nov. 5 in Pediatrics.

Ikechukwu U. Ogbuanu, M.D., M.P.H., Ph.D., of the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues offered a third dose of the MMR vaccine to over 2,000 eligible sixth- to 12th-grade students in a religious community in the Northeast affected by a large mumps outbreak, despite high two-dose MMR vaccine coverage.

The researchers found that, overall, 96.2 percent had documentation showing they had received two previous doses of MMR vaccine, and 80.6 percent chose to receive a third vaccine dose. The overall attack rate was statistically significantly reduced, from 4.93 percent before vaccination to 0.13 percent after the third dose was administered. In the village, the overall attack rate was reduced by 75.6 percent after the intervention, with the greatest effects observed in the 11- to 17-year-old age group.

"Our study assessed the use of a third MMR vaccine dose for mumps outbreak control in a setting with preexisting high two-dose vaccine coverage," the authors write. "The findings suggest a potential role of MMR vaccine for outbreak control in such limited settings."

Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

Abdominal Pain: An Approach to a Challenging Diagnosis
AACN Advanced Critical Care, July/September 2014
Free access will expire on October 13, 2014.

HIPAA Compliance Practice Tips
Professional Case Management, July/August 2014
Free access will expire on September 29, 2014.

Follow the leader: How does “followership” influence nurse burnout?
Nursing Management, August 2014
Free access will expire on September 29, 2014.

More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events