Disc Disease Severity Doesn't Predict Surgical Outcomes

Measures of disc degeneration not linked to patient's outcome after total disc replacement

THURSDAY, Nov. 8 (HealthDay News) -- Increasing severity of degenerative disc disease (DDD) does not impact outcomes in total lumbar disc replacement (TDR), according to a study published in the November issue of the European Spine Journal.

Christoph J. Siepe, M.D., Ph.D., from the Schön Klinik Munich Harlaching in Germany, and colleagues correlated data for 51 patients from prospective histological, X-ray, and magnetic resonance imaging investigation of the degree of DDD with each patient's pre- and postoperative clinical outcomes.

During an average follow-up of 51 months, the researchers found that, compared with preoperative levels, the postoperative visual analog scale (VAS) and Oswestry Disability Index (ODI) scores improved significantly. There were significant correlations and interdependence noted between various parameters of DDD before surgery. Degenerative changes of nucleus pulposus were more pronounced than that of annulus fibrosus, and these were not correlated. The extent of DDD was not significantly associated with the patient's symptomatology before surgery. Increasing stage of DDD did not negatively influence the postoperative clinical outcome parameters following TDR. Lower disc space height scores were not linked to inferior clinical results as indicated by postoperative VAS or ODI scores, or subjective outcome at the last follow-up. Patients with more severe histological degeneration scores of nucleus pulposus samples before surgery had significantly lower VAS scores soon after surgery.

"Increasing stages of DDD did not negatively impact on the outcome following TDR in a highly selected patient population. In particular, no preoperative DDD threshold value was identified from which an inferior postoperative outcome could have been deduced," the authors write. "Conversely, some positive effects on the postoperative outcome were detected in patients with advanced stages of DDD."

Abstract
Full Text

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95


The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95


Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.


Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.


Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events