ACR: Overweight, Obesity Tied to Increased RA Risk in Women

Being overweight, obese has stronger effect on risk for seronegative than seropositive RA

MONDAY, Nov. 12 (HealthDay News) -- Being overweight or obese increases the risk of developing rheumatoid arthritis (RA), according to a study presented at the annual meeting of the American College of Rheumatology, held from Nov. 10 to 14 in Washington, D.C.

Bing Lu, M.D., Dr.P.H., from Brigham and Women's Hospital in Boston, and colleagues examined the correlation between overweight and obesity and the risk of RA using data from the Nurses' Health Study (NHS) and NHSII.

The researchers found that 1,292 incident cases of RA developed (903 in NHS and 389 in NHSII). Compared with women with a body mass index <25 kg/m², overweight and obese women had a significantly increased risk of RA, with a hazard ratio (HR) of 1.19 (95 percent confidence interval [CI], 1.03 to 1.38) for overweight and 1.18 (95 percent CI, 0.98 to 1.42) for obesity (P trend = 0.029) in NHS. In NHSII, the HRs were significantly increased for both overweight and obesity (HRs, 1.78 and 1.73, respectively; P trend < 0.001). The effect of overweight and obesity on RA risk was stronger in seronegative RA than in seropositive RA. For seronegative RA, the risks for overweight and obese were significantly increased (HR, 1.30 and 1.34, respectively), while for seropositive, the HRs were 1.12 (95 percent CI, 0.92 to 1.36) and 1.08 (95 percent CI, 0.84 to 1.38), respectively.

"This study examining the potential role of obesity and overweight in [the] development of RA may furnish novel information about the etiology of RA, and have large potential public health implications," Lu said in a statement.

Abstract
More Information

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

Abdominal Pain: An Approach to a Challenging Diagnosis
AACN Advanced Critical Care, July/September 2014
Free access will expire on October 13, 2014.


HIPAA Compliance Practice Tips
Professional Case Management, July/August 2014
Free access will expire on September 29, 2014.


Follow the leader: How does “followership” influence nurse burnout?
Nursing Management, August 2014
Free access will expire on September 29, 2014.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events