HCV-Related Transplants Most Needed By Those Born 1941-60

Demand for liver transplants driven by HCV-associated hepatocellular carcinoma

THURSDAY, Dec. 13 (HealthDay News) -- Patients born between 1941 and 1960 are creating the largest demand for liver transplants due to hepatitis C virus (HCV)-associated liver disease, according to a study published in the December issue of Liver Transplantation.

Scott W. Biggins, M.D., from the University of Colorado in Denver, and colleagues used data from the Organ Procurement and Transplantation Network to identify all new adult liver transplant candidates from 1995 to 2010, including those with HCV with or without hepatocellular carcinoma (HCC).

The researchers identified 126,862 new, primary registrants for liver transplantation, including 41 percent with HCV. There were significant differences in the number of new registrants with HCV by age, indicative of a birth cohort effect. The birth cohorts with the highest frequency of HCV (from highest to lowest) were those born 1951 to 1955, 1956 to 1960, 1946 to 1950, and 1941 to 1945. Those born from 1941 to 1960 accounted for 81 percent of all new registrants with HCV. In the 1941 to 1960 birth cohorts there was a four-fold increase in new registrants with HCV and HCC between calendar years 2000 to 2010.

"Over the coming decade, the projected increase in demand for liver transplantation from an aging HCV-infected population will challenge the liver transplant community to reconsider current treatment paradigms," the authors write.

Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

What internal motivators drive RNs to pursue a BSN?
Nursing2014 , October 2014
Free access will expire on November 24, 2014.

Breast Cancer Risk Assessment in Primary Care
MCN, The American Journal of Maternal/Child Nursing, September/October 2014
Free access will expire on November 10, 2014.

Nurses spurring innovation
Nursing Management, October 2014
Free access will expire on November 10, 2014.

More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events