FDA: Chantix May Raise Risk for Cardiovascular Events

FDA advises consideration of risks and benefits

THURSDAY, Dec. 13 (HealthDay News) -- People who take the smoking cessation drug Chantix may be at increased risk for major adverse cardiovascular events (MACE), according to a Dec. 12 Drug Safety Coummnication bulletin posted by the U.S. Food and Drug Administration.

The agency's cautionary stance is based on the findings of a meta-analysis it insisted the manufacturer of Chantix conduct to evaluate the cardiovascular safety of the drug. The study revealed a higher rate of MACE in the 4,190 patients who took Chantix compared to the 2,812 who took a placebo. The difference between the two groups did not reach statistical significance but still raised concerns for those taking the drug.

The FDA advises health care professionals to weigh the risks of Chantix against its possible benefits, noting that smoking is a major risk factor for cardiovascular disease and that the drug has been shown to be effective in helping smokers quit.

The Agency suggests that health care professionals "counsel patients to seek medical attention if they experience new or worsening symptoms of cardiovascular disease while taking Chantix" and "encourage patients to read the Medication Guide they receive along with their Chantix prescription."

More Information

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

Meeting the Needs of Family Members of ICU Patients
Critical Care Nursing Quarterly, October/December 2014
Free access will expire on December 22, 2014.


Dealing with the specter of phantom limb pain
Nursing2014 , November 2014
Free access will expire on December 8, 2014.


The Power of Nursing Peer Review
JONA: Journal of Nursing Administration, November 2014
Free access will expire on December 8, 2014.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events