Income Affects Oncology Clinical Trial Participation

Lower-income patients significantly less likely to participate in oncology clinical trials

WEDNESDAY, Jan. 16 (HealthDay News) -- Oncology patients with lower income, even older patients with access to Medicare, are significantly less likely to participate in clinical trials, according to research published online Jan. 7 in the Journal of Clinical Oncology.

Joseph M. Unger, Ph.C., of the Fred Hutchison Cancer Research Center in Seattle, and colleagues assessed clinical trial participation patterns according to socioeconomic and demographic factors for 5,499 oncology patients using an Internet-based treatment decision tool.

The researchers found that 40 percent of patients discussed clinical trials with their physicians; of these discussions, 45 percent led to offers of clinical trial participation, and about half (51 percent) of these offers led to participation in clinical trials. Overall, the rate of participation in clinical trials was 9 percent. Based on univariate analysis, participation was significantly less likely for older patients and patients with lower income and education. Income remained a significant predictor of clinical trial participation in multivariable analysis (odds ratio, 0.73). For patients aged 65 years and older with universal access to Medicare, lower income still predicted lower participation in trials. Among lower-income patients, cost concerns were more evident.

"Because clinical trials offer the newest cancer treatments, equal access to this important resource for patients of all income groups is essential. Also, improved lower-income participation would allow clinical trials to be conducted more quickly and would better ensure the applicability of trial results to all income levels (i.e., generalizability)," the authors write. "Understanding that income is related to clinical trial participation could help guide policy decisions aimed at increasing access for lower-income patients."

One author disclosed financial ties to NexCura.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2013 HealthDay. All rights reserved.

Powered by

Featured Jobs



Benefits of Membership

FREE E-Newsletters
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues

CESaver
Join our CESaver program to earn up to 100 contact hours for only $34.95
Register Now

Lippincott's NursingCenter.com
Explore a world of online resources

Become a Member