Venous Thromboembolism, PE Risk Up in IVF Pregnancies

Although absolute risks are small, risk of VTE, pulmonary embolism increased during first trimester

THURSDAY, Jan. 17 (HealthDay News) -- Pregnant women have an increased risk of venous thromboembolism and pulmonary embolism after in vitro fertilization (IVF), especially during the first trimester, according to a study published online Jan. 15 in BMJ.

Peter Henriksson, M.D., of the Karolinska Institutet in Stockholm, and colleagues conducted a cross-sectional study to estimate the risk of pulmonary embolism and venous thromboembolism during the pregnancy and in each trimester after IVF. The population comprised 23,498 women who had given birth following IVF between 1990 and 2008, who were matched with 116,960 women with natural pregnancies.

The researchers observed a significantly increased risk of venous thromboembolism after IVF versus natural pregnancies (4.2 versus 2.5 per 1,000 women; hazard ratio, 1.77). The increased risk was seen during the whole pregnancy and varied between the trimesters, with a particular increase noted during the first trimester (1.5 versus 0.3 per 1,000 women; hazard ratio, 4.22). During the first trimester, significantly more women experienced pulmonary embolism after IVF versus natural pregnancy (3.0 versus 0.4 per 10,000 women; hazard ratio, 6.97).

"Our results show an increased risk of thromboembolism and, importantly, pulmonary embolism in pregnant women after in vitro fertilization," the authors write. "Doctors should be aware of these increased risks because the symptoms of pulmonary embolism can be insidious and the condition is potentially fatal."

Full Text

Copyright © 2013 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

Medical Marijuana: A Hazy State of Affairs for Nurses
AJN, American Journal of Nursing, August 2014
Free access will expire on October 27, 2014.


Understanding nonalcoholic fatty liver disease
Nursing Made Incredibly Easy!, September/October 2014
Free access will expire on October 13, 2014.


Assessing pain in critically ill adults
Nursing2014 Critical Care, July 2014
Free access will expire on October 13, 2014.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events