View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
WEDNESDAY, Jan. 16 (HealthDay News) -- Pandemic influenza A (H1N1) infection in pregnancy is associated with an increased risk of fetal death, and vaccination is associated with a non-significant reduction in the risk of fetal death, according to a study published online Jan. 16 in the New England Journal of Medicine.
Siri E. Håberg, M.D., from the Norwegian Institute of Public Health in Oslo, and colleagues linked Norwegian national registries and medical consultation data to explore the safety of influenza vaccination of pregnant women among 117,347 eligible pregnancies in Norway from 2009 through 2010.
Within the sample, fetal mortality was 4.9 deaths per 1,000 births. During the 2009 influenza pandemic, the researchers found that 54 percent of pregnant women were vaccinated in their second or third trimester. The risk of an influenza diagnosis was significantly reduced with vaccination during pregnancy (adjusted hazard ratio [aHR], 0.30). The risk of fetal death was significantly increased among pregnant women with a clinical diagnosis of influenza (aHR, 1.91). Vaccination during pregnancy correlated with a non-significant reduction in the risk of fetal death (aHR, 0.88; 95 percent confidence interval, 0.66 to 1.17).
"Given the danger posed by maternal influenza virus infection for fetal survival, our study adds to growing evidence that vaccination of pregnant women during an influenza pandemic does not harm -- and may benefit -- the fetus," the authors write.
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top