Single- and dual-chamber devices associated with similar mortality and hospitalization rates
TUESDAY, May 14 (HealthDay News) -- Single- and dual-chamber implantable cardioverter-defibrillators (ICDs) for primary prevention of sudden cardiac death are associated with similar one-year mortality and hospitalization outcomes, although single-chamber devices are associated with lower complication rates, according to a study published in the May 15 issue of the Journal of the American Medical Association.
Pamela N. Peterson, M.D., M.S.P.H., from the Denver Health Medical Center, and colleagues retrospectively analyzed outcomes from 32,034 patients (65 years and older) who received an ICD for primary prevention, where 38 percent received a single-chamber device and 62 percent received a dual-chamber device.
The researchers found that complication rates were significantly lower for single-chamber devices (3.51 versus 4.72 percent). However, single- and dual-chamber devices were associated with similar one-year mortality rates (9.85 and 9.77 percent, respectively; hazard ratio [HR], 0.99), one-year all-cause hospitalization (43.86 and 44.83 percent, respectively; HR, 1.00), and hospitalization for heart failure (14.73 and 15.38 percent, respectively; HR, 1.05).
"Among patients receiving an ICD for primary prevention without indications for pacing, the use of a dual-chamber device compared with a single-chamber device was associated with a higher risk of device-related complications and similar one-year mortality and hospitalization outcomes," Peterson and colleagues write.
One author disclosed receiving an educational travel grant from Boston Scientific.
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