CLINICAL QUERIES: Managing hypernatremia
Judith Sweeney MSN, RN

September 2010 
Volume 40  Number 9
Pages 63 - 63
  PDF Version Available!

My patient's serum sodium level was 153 mEq/L (normal, 135 to 145 mEq/L) and the healthcare provider prescribed an infusion of 5% dextrose in 0.45% sodium chloride solution. Why was a hypertonic, instead of a hypotonic, I.V. solution used to treat this patient's hypernatremia?—E.E., OKLA.Judith Sweeney, MSN, RN, replies:Osmolality, which reflects the concentration of solutes such as sodium and glucose in water, is indicated on the I.V. solution container. Tonicity refers to the effect that a solution's osmolality has on cell size because of water movement across the cell membrane.1 Because 0.9% sodium chloride solution is considered physiologically equal to the osmolality of plasma, it's an isotonic solution.Solutions with a higher concentration of solutes (such as sodium or glucose) than isotonic solutions are hypertonic. They increase the osmotic pressure in plasma, pulling fluid from the intracellular and interstitial spaces into the vascular compartment

Purchase Now !

To purchase this item, follow the instructions below. If you’re not already logged in, be sure to enter your login information below to ensure that your item is saved to your File Drawer after you purchase it.

Not a member? Join now for Free!

1) If you're not already logged in, enter your information below to save this item in your File Drawer for future viewing.

User name:


Forgot your user name or password?
2)  If you have a coupon or promotional code, enter it
here.(If not, just click Continue.

Digital Coupon: (optional)

3)  Click Continue to go to the next screen, where
you'll enter your payment details.

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events