New hope for those with Hereditary Angioedema
June Pepe LPN, CCRC
Leonard Bielory MD

$7.95
Nursing2014
April 2012 
Volume 42  Number 4
Pages 43 - 46
 
  PDF Version Available!

ABSTRACT
OUR PATIENT, AN, had been diagnosed with hereditary angioedema (HAE) when she was 4 years old. At diagnosis, AN's signs and symptoms were limited to gastrointestinal (GI) attacks and included severe abdominal pain, diarrhea, and vomiting; she'd experienced similar GI problems since the age of 5 months.Her GI attacks had occurred two or three times a year until she started her menstrual cycle, when she began to experience monthly attacks typically lasting for 5 to 7 days. Cutaneous attacks now involved her arms, legs, face, genitals, and periorbital areas, and she experienced laryngeal attacks as well.(See Picturing HAE.)This article explains this rare, life-threatening genetic disorder, including how it's diagnosed and treated. It also describes how new treatment is improving the outcomes for patients with HAE.HAE affects 1 in 50,000 people, according to estimates; the range is reported to be from 1 in 10,000 to 1 in 150,000. Men and women are affected equally. Although patients are usually diagnosed in their second or third decade of life, many patients' symptoms begin earlier. Attacks usually become more frequent after the patient reaches puberty.1 The pattern of signs and symptoms varies considerably between patients and in individual patients. HAE is characterized by recurrent episodes of nonpainful, nonpruritic, nonurticaric angioedema (swelling of deep dermis, subcutaneous, or submucosal tissue due to vascular leakage) that most commonly affects the skin and mucosal tissues of the upper respiratory and GI tracts.1,2 The swelling, which typically develops gradually over several hours, may resolve over 2 to 4 days without treatment. Many patients with HAE have a prodromal cutaneous eruption involving the extremities, chest wall, and abdomen and consisting of a mottled reticulated vascular pattern that appears as an intricate lace-like purplish discoloration. It's similar to livedo reticularis except that it's not limited to the lower extremities. Cutaneous attacks

Purchase Now !

To purchase this item, follow the instructions below. If you’re not already logged in, be sure to enter your login information below to ensure that your item is saved to your File Drawer after you purchase it.

Not a member? Join now for Free!


Cost:$7.95
1) If you're not already logged in, enter your information below to save this item in your File Drawer for future viewing.

User name:


Password


Forgot your user name or password?
2)  If you have a coupon or promotional code, enter it
here.(If not, just click Continue.


Digital Coupon: (optional)

3)  Click Continue to go to the next screen, where
you'll enter your payment details.






jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

Dogs as Pets, Visitors, Therapists and Assistants
Home Healthcare Nurse, November/December 2014
Free access will expire on January 5, 2015.


Tracheostomy Care
Nursing2014 Critical Care, November 2014
Free access will expire on December 22, 2014.


Effective management of ARDS
The Nurse Practitioner, 13December 2014
Free access will expire on December 22, 2014.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events