COMBATING INFECTION: NDM-1 The newest superbug?
Shilla Patel OD, CIC

April 2012 
Volume 42  Number 4
Pages 67 - 68
  PDF Version Available!

CARBAPENEMASES ARE carbapenem-hydrolyzing beta-lactamases produced by some bacteria that allow them to become resistant to penicillins, cephalosporins (such as cefazolin, cefuroxime, ceftriaxone, and cefepime), and carbapenems (such as imipenem, meropenem, ertapenem, and doripenem). These antibiotics are used to treat life-threatening infections, and increased resistance to them is a worldwide problem.1A new form of carbapenemase that's highly resistant to antibiotics and easily transmitted has recently been identified: New Delhi metallo-beta-lactamase-1 (NDM-1). It was first described in a Swedish patient who contracted a Klebsiella pneumoniae infection while in India in late 2007.2 It was first thought to be a nosocomial pathogen limited to hospitals in India. Since then, environmental studies in India have shown widespread contamination by NDM-1-encoded bacteria that's circulating in the community as well as healthcare settings.2NDM-1 isn't the first carbapenemase to be identified.

Purchase Now !

To purchase this item, follow the instructions below. If you’re not already logged in, be sure to enter your login information below to ensure that your item is saved to your File Drawer after you purchase it.

Not a member? Join now for Free!

1) If you're not already logged in, enter your information below to save this item in your File Drawer for future viewing.

User name:


Forgot your user name or password?
2)  If you have a coupon or promotional code, enter it
here.(If not, just click Continue.

Digital Coupon: (optional)

3)  Click Continue to go to the next screen, where
you'll enter your payment details.

Featured Jobs

Benefits of Membership

FREE E-Newsletters
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues

Join our CESaver program to earn up to 100 contact hours for only $34.95
Register Now

Explore a world of online resources

Become a Member