EYE ON DIAGNOSTICS: Predicting heart disease with C-reactive protein

May 2003 
Volume 33  Number 5
Pages 70 - 71
  PDF Version Available!


  • Testing for CRP

  • What to teach the patient

  • Is my patient at risk?


  • Graphics

  • Table. No caption av...

  • ALTHOUGH LIPID profiles help determine a patient's risk of cardiovascular disease (CVD), favorable levels can be misleading: 50% of patients who experience myocardial infarctions (MIs) have normal levels of low-density and high-density lipoproteins and triglycerides. Now researchers have found that C-reactive protein (CRP), a naturally occurring substance that rises in response to inflammation, is the leading inflammatory marker for CVD in certain patients.

    Inflammation plays a significant role in atherosclerosis development, causing plaque to rupture and activating a clotting cascade that can result in MI or stroke. Researchers are exploring whether infectious bacteria or viruses might cause or contribute to inflammation.

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