DRUG NEWS: Nitrates may wear out cartilage

April 2004 
Volume 34  Number 4
Pages 10 - 10
  PDF Version Available!


  • Source

    Elderly women who take nitrate drugs may be at increased risk for developing hip osteoarthritis, according to new research. For more than 8 years, researchers followed almost 6,000 white women age 65 or older. They surveyed them twice for nitrate use and conducted pelvic radiographs at the start and end of the study.

    During the follow-up period, 566 women developed new joint-space narrowing in one or both hips. After adjusting the data for age, height, weight, bone mineral density, and estrogen use, researchers found that women who reported using nitrate drugs (mainly sublingual nitroglycerin) were significantly more likely to have joint-space narrowing than women who didn't report using nitrate drugs. They didn't detect any association between the dose of nitrate drugs a woman took and her likelihood of developing osteoarthritis.

    Researchers say that their findings provide some evidence that nitrate drugs increase nitric ...

Purchase Now !

To purchase this item, follow the instructions below. If you’re not already logged in, be sure to enter your login information below to ensure that your item is saved to your File Drawer after you purchase it.

Not a member? Join now for Free!

1) If you're not already logged in, enter your information below to save this item in your File Drawer for future viewing.

User name:


Forgot your user name or password?
2)  If you have a coupon or promotional code, enter it
here.(If not, just click Continue.

Digital Coupon: (optional)

3)  Click Continue to go to the next screen, where
you'll enter your payment details.

Featured Jobs

Benefits of Membership

FREE E-Newsletters
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues

Join our CESaver program to earn up to 100 contact hours for only $34.95
Register Now

Lippincott's NursingCenter.com
Explore a world of online resources

Become a Member