DRUG NEWS: Statin under fire

June 2004 
Volume 34  Number 6
Pages 30 - 30
  PDF Version Available!

© 2004 Lippincott Williams & Wilkins, Inc. Volume 34(6)             June 2004             p 30 Statin under fire [DRUG NEWS: LIPID-LOWERING DRUG]

The consumer group Public Citizen has filed a petition with the FDA seeking to remove Crestor (rosuvastatin) from the market because of dangerous adverse reactions. Crestor, a lipid-lowering drug, was first marketed in the United States in September 2003. Since then, seven patients developed rhabdomyolysis, a potentially fatal condition involving the breakdown of muscle tissue, and nine experienced kidney failure or damage. One woman died from rhabdomyolysis and kidney damage.

Rhabdomyolysis is a potential complication of all statin drugs. In 2001, the FDA removed another statin, Baycol, from the market because of several deaths from rhabdomyolysis worldwide.

Crestor won FDA approval despite concerns about its potential to cause rhabdomyolysis, ...

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