MICHAEL R. COHEN RPH, MS, ScD, President of the Institute for

November 2004 
Volume 34  Number 11
Pages 22 - 22
  PDF Version Available!

© 2004 Lippincott Williams & Wilkins, Inc. Volume 34(11)             November 2004             p 22 Not so fast! [MEDICATION ERRORS: IMMEDIATE-RELEASE NIFEDIPINE]

COHEN, MICHAEL R. RPH, MS, ScD, President of the Institute for Safe Medication Practices

A pharmacist noticed that the ED physician had ordered “Procardia, 10 mg P.O. every 2 hours p.r.n. hypertension” after a patient was admitted to the hospital through the ED. The calcium channel blocker capsule nifedipine (Procardia and generics) is intended to treat angina, but some practitioners have prescribed sublingual or oral doses to treat acute hypertension.

Both the FDA and the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure consider this practice unacceptable. Several well-documented reports describe patients developing profound hypotension, cerebrovascular ischemia, ...

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