EYE ON DIAGNOSTIC: Gauging cardiovascular risk with the PLAC test
RAYMONDE A. BROWN APRN, BC, PHD

$3.95
Nursing2014
August 2006 
Volume 36  Number 8
Pages 17 - 17
 
  PDF Version Available!

ABSTRACT

BROWN, RAYMONDE A. APRN, BC, PHD

USED TO GAUGE a patient's risk of coronory heart disease (CHD) and stroke, the PLAC test measures lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) levels in the blood. A cardiovascular-specific inflammatory enzyme, Lp-PLA 2 resides mainly on low-density lipoprotein (LDL) cholesterol and contributes to the formation of atherosclerotic plaque that's vulnerable to rupture.

According to the Atherosclerosis Risk in Communities study, elevated blood Lp-PLA 2 levels can provide early evidence of risk even when blood LDL levels are normal (less than 130 mg/dL). This study found an elevation of Lp-PLA 2 to be independently associated with CHD, even after adjustment for traditional risk factors and C-reactive protein (CRP).

Arterial plaque is thought to result largely from an inflammatory process. At areas of disruption to the intima, LDL and Lp-PLA 2 enter the intima, where LDL is oxidized and Lp-PLA 2 triggers proinflammatory and proatherogenic ...

Purchase Now !

To purchase this item, follow the instructions below. If you’re not already logged in, be sure to enter your login information below to ensure that your item is saved to your File Drawer after you purchase it.

Not a member? Join now for Free!


Cost:$3.95
1) If you're not already logged in, enter your information below to save this item in your File Drawer for future viewing.

User name:


Password


Forgot your user name or password?
2)  If you have a coupon or promotional code, enter it
here.(If not, just click Continue.


Digital Coupon: (optional)

3)  Click Continue to go to the next screen, where
you'll enter your payment details.






Featured Jobs



Benefits of Membership

FREE E-Newsletters
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues

CESaver
Join our CESaver program to earn up to 100 contact hours for only $34.95
Register Now

Lippincott's NursingCenter.com
Explore a world of online resources

Become a Member