WOUND & SKIN CARE: Understanding pemphigus

August 2006 
Volume 36  Number 8
Pages 26 - 26
  PDF Version Available!


PEMPHIGUS IS A GROUP of serious diseases of the skin characterized by the appearance of bullae (blisters) of various sizes on apparently normal skin and mucous membranes. In this acquired autoimmune disease involving immunoglobulin G, the pemphigus antibody is directed against a specific antigen in the surface of epidermal cells. A blister forms from the antigen-antibody reaction.

The level of serum antibody predicts disease severity. Genetic factors also may play a role in the development of pemphigus; the highest incidence of the disease is among patients of Jewish or Mediterranean descent. The disease usually occurs in men and women in middle and late adulthood, and may be associated with penicillins, captopril, and myasthenia gravis.

Signs and symptoms

Most patients have oral lesions appearing as irregularly shaped erosions that are painful, bleed easily, and heal slowly. The skin bullae enlarge, rupture, and leave large, painful eroded areas accompanied by crusting and oozing. A characteristic ...

Purchase Now !

To purchase this item, follow the instructions below. If you’re not already logged in, be sure to enter your login information below to ensure that your item is saved to your File Drawer after you purchase it.

Not a member? Join now for Free!

1) If you're not already logged in, enter your information below to save this item in your File Drawer for future viewing.

User name:


Forgot your user name or password?
2)  If you have a coupon or promotional code, enter it
here.(If not, just click Continue.

Digital Coupon: (optional)

3)  Click Continue to go to the next screen, where
you'll enter your payment details.

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events