Med Check: Stuck on you: Transdermal drug patches
LISA SCHULMEISTER RN, CS, OCN, MN, FAAN

$3.95 		Nursing Made Incredibly Easy!
April 2007 
Volume 5  Number 2
Pages 17 - 19
 
  PDF Version Available!

ABSTRACT

SCHULMEISTER, LISA RN, CS, OCN, MN, FAAN

Clinical Nurse Specialist, Medical/Surgical Nursing and Oncology, New Orleans, La. Figure. No caption available.

A: Although the skin functions as a protective barrier, it's permeable to many substances, including certain drugs (see Guide to patches ).

When placed on intact skin, a transdermal drug patch creates a concentration gradient between the high concentration of drug in the patch and the low concentration in the skin. The drug diffuses passively from the patch across the stratum corneum (the outermost layer of the skin) into capillaries of the epidermis (see Anatomy of a patch ).

Q: What are the advantages and potential drawbacks of patches?

A: Transdermal drug patches provide convenient, controlled, and continual drug delivery while sidestepping many problems associated with oral drug delivery, such as bloating, nausea, and vomiting, and parenteral drug administration, such as discomfort and increased infection ...

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