View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
In a review of about 200 placebo-controlled studies involving 11 common antiepileptic drugs (AEDs), patients taking the drugs experienced about twice the risk of suicidal thoughts or behavior as people who took placebos. The research has prompted the Food and Drug Administration (FDA) to issue an alert to health care providers.
Overall, suicidal thoughts or behavior were rare, but four people in the groups taking AEDs committed suicide, compared with none in the placebo groups. And 0.43% of those receiving AEDs experienced suicidal thoughts or behavior, compared with 0.22% in the placebo groups. The risks occurred at 1 week after starting a drug and continued for at least 24 weeks.
An FDA spokesperson said the FDA would work with drug manufacturers to add a warning to drug labels. Although only 11 drugs were studied in the research, the FDA expects that all drugs classified as AEDs carry the same risk.
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top