Retinopathy Severity Linked to Cardiovascular Outcome

In type 2 diabetes, retinopathy severity and progression are determinants of CV outcomes

THURSDAY, Jan. 24 (HealthDay News) -- For individuals with type 2 diabetes, incident cardiovascular outcomes are determined not only by the severity of diabetic retinopathy but also by its progression, according to research published online Dec. 13 in Diabetes Care.

Hertzel C. Gerstein, M.D., of McMaster University in Hamilton, Canada, and colleagues examined the correlation between retinopathy, four-year progression, and cardiovascular outcomes (cardiovascular death, nonfatal myocardial infarction, or stroke) using data from 3,433 participants in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial and ACCORD Eye Study, who had baseline retinal photographs.

The researchers found that the adjusted hazard ratio for cardiovascular outcome increased from 1.49 for mild retinopathy to 2.35 for severe retinopathy, compared with no retinopathy. For a subset of 2,856 participants evaluated for disease progression at four years, for each category of change in retinopathy severity, the risk of the primary outcome increased by 38 percent. The correlation between progression and cardiovascular outcomes was no longer significant after adjustment for the baseline and follow-up levels of glycated hemoglobin, systolic blood pressure, and lipids either individually or together.

"The clear link between progression of retinal disease and cardiovascular disease suggests that these two serious consequences of diabetes may share an underlying pathophysiological basis," the authors write.

Abstract
Full Text (subscription or payment may be required)

Health News Copyright © 2013 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95


The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95


Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.


Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.


Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events