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AMA Examines Economic Impact of Physicians
Each physician contributes $2.2 million in economic output, supports 13.84 jobs on average
Friday, April 18, 2014

FDA Approves Ragwitek for Adult Ragweed Allergy
Tablet placed under the tongue
Friday, April 18, 2014

Free Drug Samples Tied to More Branded Prescriptions
Total retail cost of acne Rx twice as high for those at practices given free drug samples
Friday, April 18, 2014

Trust in Provider Improves Antidepressant Adherence in DM
Patients with diabetes who perceive lack of shared decision-making found less adherent in Rx strategy
Friday, April 18, 2014

White House: 8 Million People Signed Up for Health Insurance
35 percent of registrants are younger than 35 years old, administration officials say
Friday, April 18, 2014

Informed Patients Question Unnecessary Prescriptions
Educated sleeping pill users more likely to discuss quitting potentially harmful meds
Wednesday, April 16, 2014

CDC: Regional Trends Seen for Complementary Health Services
U.S. study shows geographic trends in use of complementary and alternative medicine
Wednesday, April 16, 2014

Continued Reliance on Windows XP May Threaten Data Security
Continued security of patient data needed following Microsoft's termination of XP support
Wednesday, April 16, 2014

Evidence Lacking for Long-Term Opioid Use in Low Back Pain
Review finds efficacy of short-term opioid use for chronic low back pain relief and function
Wednesday, April 16, 2014

Extensive Atypical Antipsychotic Use in Medicaid-Insured Youth
ADHD-diagnosed foster care youth have increased odds of atypical antipsychotic use
Wednesday, April 16, 2014

Patients Paying Much More for Specialty Drugs
Many Americans paying less for Rx, but some having to deal with sharp rises in cost of specialty meds
Tuesday, April 15, 2014

FDA Approves Tanzeum for Type 2 Diabetes
To be used in conjunction with diet and exercise
Tuesday, April 15, 2014

iPLEDGE Isotretinoin Counseling May Need Updating
Women need expanded info about effective contraceptive choices, including reversible ones
Tuesday, April 15, 2014

NSAIDs With Anticoagulant Tx Ups Major Bleeding in VTE
Increases in clinically relevant, major bleeding seen in venous thromboembolism patients
Tuesday, April 15, 2014

New Health Secretary to Confront Health Care Reform Hurdles
Obama's nominee, Sylvia Mathews Burwell, will seek to burnish ACA's image amid mid-term election fray
Monday, April 14, 2014

AAFP Provides Tips to Address Patients' Vaccine Concerns
Physicians must be prepared to explain the risks and benefits of vaccinations
Monday, April 14, 2014

Prenatal SSRI Exposure May Up Odds of Autism in Boys
Strongest correlation seen for first trimester; link also seen for developmental disorder
Monday, April 14, 2014

Blood Glucose Levels Set for Achieving HbA1c Targets
Average blood glucose levels at premeal, postmeal, bedtime established for achieving HbA1c targets
Friday, April 11, 2014

Sebelius Stepping Down As HHS Secretary
Tenure was marred by troubled introduction of Affordable Care Act
Friday, April 11, 2014

ILC: Interferon-Free Combo Has >95% Virologic Response
Findings among HCV genotype 1 patients previously treated with peginterferon-ribavirin
Thursday, April 10, 2014

Updated Reviews Issued for Oseltamivir, Zanamivir Use in Flu
Systematic reviews of regulatory information seeking evidence for prevention, treatment of flu
Thursday, April 10, 2014

Financial Incentives Improve Completion of HBV Vaccination
Significant improvement in vaccine adherence seen in patients receiving heroin treatment
Thursday, April 10, 2014

NSAID Use Linked to Increased Risk of Atrial Fibrillation
Among elderly individuals, increased risk for current, recent use compared with never-use
Thursday, April 10, 2014

Fewer Americans Overwhelmed by Medical Bills
Reduced use of medical care, early health care reforms may be easing financial worries
Wednesday, April 09, 2014

Some Doctors Paid at Least $3 Million Each by Medicare
In total, Medicare paid individual physicians nearly $64 billion in 2012
Wednesday, April 09, 2014

NCQA Updates Recognition Standards for Medical Homes
Patient-centered medical homes should focus on care coordination, behavioral health integration
Tuesday, April 08, 2014

Newly Eligible for Expanded Medicaid Are Healthier
Findings based on comparisons between newly eligible under ACA and pre-ACA enrollees
Monday, April 07, 2014

USPSTF Recommends Low-Dose Aspirin to Prevent Preeclampsia
Low-dose aspirin recommended after 12 weeks for women at high-risk of preeclampsia
Monday, April 07, 2014

Vitamin D Supplementation May Be Beneficial in Depression
Review shows no overall effect on symptoms, but may have effect in clinically significant depression
Monday, April 07, 2014

AMA Provides Resources to Aid Physicians' Collections
Resources help address physicians' financial risk during the ACA's 90-day premium grace period
Friday, April 04, 2014

Study Examines Fertility Drug Effect on Breast Cancer Risk
No increased risk with ever use of clomiphene; inconsistent association for gonadotropin use
Thursday, April 03, 2014

Half of Uninsured Don't Intend to Sign Up for Health Coverage
Kaiser Family Foundation poll shows most respondents unaware of March 31 deadline
Wednesday, April 02, 2014

FDA Approves Sublingual Tablet for Grass Allergies
To be started four months before allergy season
Wednesday, April 02, 2014

ACEIs, Not ARBs, Reduce Cardiac Mortality in Diabetes
No reduction in all-cause, cardiovascular mortality with angiotensin II receptor blockers
Wednesday, April 02, 2014

Lack of Clear Evidence for Health Benefits of Vitamin D
Second review suggests increased risk of death for lowest versus highest levels of 25-hydroxyvitamin D
Wednesday, April 02, 2014

Attention to Postpartum Contraception Needed
Counseling and access to contraceptive methods are important in the postpartum period
Wednesday, April 02, 2014

CMS: Medicare Beneficiaries Saved $3.9B on Meds in 2013
In addition to savings on prescription drugs, preventive service use up for Medicare beneficiaries
Tuesday, April 01, 2014

Nearly One-Third of Initial Prescriptions Remain Unfilled
Primary prescription nonadherence is common among primary care patients
Tuesday, April 01, 2014

NCHS Estimates Health Insurance Coverage for 2013
At time of interview, 14.5 percent uninsured; 10.8 percent uninsured for more than one year
Thursday, March 27, 2014

Adjunct Social Media Improves Contraceptive Knowledge
Participants receiving Facebook info have better knowledge, more likely to use long-acting contraceptives
Thursday, March 27, 2014

Nitroglycerin Shortage Has Medical Community Worried
Baxter and the FDA taking action to ease the shortage
Wednesday, March 26, 2014

White House Extends Affordable Care Act Enrollment Deadline
Applicants need to check a box on HealthCare.gov website to gain added time, report says
Wednesday, March 26, 2014

Americans Seem Unprepared for Health Insurance Exchanges
Half the population do not know about exchanges; 42 percent unable to correctly describe deductible
Wednesday, March 26, 2014

E-Cigarette Use Does Not Up Quitting, Reduce Smoking
Baseline e-cigarette use does not significantly predict quitting smoking one year later
Tuesday, March 25, 2014

Nicotine 'E-Liquids' Pose Serious Health Threat
Children at special risk because they may be attracted by e-liquids' bright colors, appealing flavors
Monday, March 24, 2014

Practices Can Take Steps to Improve Care Transitions
Financial incentives exist, including reimbursement and avoiding hospital readmissions
Friday, March 21, 2014

New Guidelines Expand Statin Eligibility by 13 Million
Increase largely driven by eligibility of adults without cardiovascular disease
Thursday, March 20, 2014

Review: Tamiflu Saved Lives During Swine Flu Pandemic
Best to start treatment within 48 hours, experts say
Wednesday, March 19, 2014

Penicillin 'Allergy' Complicates Inpatient Care
Patients with a history of penicillin 'allergy' have longer hospital stays and increased risk of infection
Tuesday, March 18, 2014

Rx Expenditures Expected to Rise in 2014
2013 pharmaceutical spending slowed 0.7 percent, compared to 2012
Monday, March 17, 2014

Insurers Must Offer Same-Sex Couples Spousal Benefits
Insurers must offer same-sex couples same spousal benefits as heterosexual couples
Monday, March 17, 2014

Improving EHR Interoperability Is a National Priority: HHS
Interoperability necessary to achieve the benefits of EHR infrastructure adoption
Friday, March 14, 2014

Nicotine Patches Deemed Ineffective for Pregnant Smokers
No difference in smoking cessation rates between pregnant women using nicotine, placebo patches
Friday, March 14, 2014

Benefits of Faster Thrombolysis Time Quantified
Each minute of onset-to-treatment time saved linked to 1.8 extra days of healthy life
Friday, March 14, 2014

Gel May Offer Postexposure Protection Against HIV Infection
Vaginal gel with integrase inhibitors shows effectiveness in preventing infection in macaques
Friday, March 14, 2014

Health Education Not Routinely Provided to Patients
Physician assistants, nurse practitioners more often provide education than physicians
Thursday, March 13, 2014

Glucosamine Fails to Prevent Knee Cartilage Deterioration
Additionally, glucosamine does not decrease pain or improve knee bone bruises
Thursday, March 13, 2014

Oldest Old at High Risk for Insulin-Related Hypoglycemia
Patients 80 years or older more likely to visit the ER and be hospitalized for insulin-related errors
Thursday, March 13, 2014

Info, Motivation, Behavioral Skill Affect Med Adherence
Study suggests Information-Motivation-Behavioral skills model applicable to diabetes
Wednesday, March 12, 2014

Resistant Strain of Head Lice Prevalent in North America
High frequency of knockdown-type resistance allele found in Canada and the United States
Wednesday, March 12, 2014

Discrepancies ID'd in Studies on ClinicalTrials.gov, Journals
Nearly all clinical trials have at least one discrepancy in cohort, intervention, or results
Tuesday, March 11, 2014

Medicare Drug Plan Changes Withdrawn by White House
Proposal met heavy resistance from patient groups
Tuesday, March 11, 2014

White House: More Than Four Million Have Signed Up for ACA
Enrollment period for coverage in 2014 ends March 31 for most Americans
Tuesday, March 11, 2014

AAPM: Oxytocin, HCG Show Promise for Intractable Pain
Seven of nine patients reported 30 to 40 percent decrease in opioid use and baseline pain
Tuesday, March 11, 2014

AAPM: Benzodiazepine Rx Increasing in Primary Care
Patient visits involving opioid prescriptions more likely to also have benzodiazepine prescriptions
Monday, March 10, 2014

AAPM: Post-Op Pain Highly Influential in Patient Satisfaction
Correlation is stronger for spine, non-spine orthopedics, OB/GYN surgeries
Monday, March 10, 2014

Marijuana Use Up, Cocaine Use Down, U.S. Report Finds
Review covered 2000 to 2010, so doesn't reflect suspected increase in heroin use
Monday, March 10, 2014

Keeping Salaries Secret Harms Worker Performance
Secret salaries decrease employees' perception that performance increase is tied to pay increase
Monday, March 10, 2014

CDC: Child Care Flu Vaccination Requirements Seem Effective
In Connecticut, implementation of the rule tied to higher vaccination, lower hospitalization rates
Friday, March 07, 2014

FDA: Pfizer Voluntarily Recalls Certain Lots of Antidepressant
Action taken after pharmacist found a heart drug among Effexor/venlafaxine, FDA says
Friday, March 07, 2014

Outpatient Abx Culprit in Most Childhood C. Difficile Cases
Nearly three-quarters of C. difficile cases associated with Rx written at doctor visits
Friday, March 07, 2014

Women More Sensitive Than Men to Sublingual Zolpidem
Greater impact on females not accounted for by drug dose, body weight
Friday, March 07, 2014

AMA Grants Curriculum Efforts to Address Health Disparities
Initiatives focus on underserved populations, workforce diversity, and population health
Friday, March 07, 2014

Palliative Chemo for Terminal Cancer Linked to Death in ICU
Use of chemotherapy at end of life also ups risk of undergoing CPR or mechanical ventilation
Friday, March 07, 2014

Physicians Better Able to Recall Narratives About Rx Guidelines
Comparisons made between recall of opioid guideline summary versus evidence-based narratives
Friday, March 07, 2014

Cautious Optimism for 'Cure' of HIV-Infected Babies
Report on second child raises hope that early, aggressive tx may be game changer for these infants
Thursday, March 06, 2014

Value-Based Insurance Plans Can Up Rx Adherence
Along with lower cost sharing, plans target high-risk patients, use mail-order drugs
Wednesday, March 05, 2014

Gap in Regulatory Coverage Affects 5 to 16 Percent of Trials
Nineteen to 24 percent of trials are overlap trials, which study drugs, devices and have federal funding
Wednesday, March 05, 2014

CDC: Antibiotics Often Prescribed During Hospitalization
Antibiotic prescribing could potentially be improved in 37.2 percent of the most common scenarios
Wednesday, March 05, 2014

Women-Specific Research Is Still Inadequate
Women underrepresented in research; many studies fail to report sex-specific outcomes
Monday, March 03, 2014

CMS: No More Delays to ICD-10 Implementation Deadline
CMS Administrator claims CMS will be ready for ICD-10 conversion by October deadline
Monday, March 03, 2014

Going Live With EHR Leads to Frustrations, Productivity Hit
Medical Economics offers some real-world suggestions, best practices to minimize stress
Friday, February 28, 2014

Hospital Size, Market Share Affect Inpatient Care Prices
Higher-price hospitals generally score well on reputational indicators
Friday, February 28, 2014

Antihypertensives Tied to Serious Fall Injuries in Elderly
Increased risk of serious fall injuries is particularly high in those with previous fall injuries
Friday, February 28, 2014

AAN: Hormonal Contraceptive Use May Contribute to MS Risk
Use of hormonal contraceptives in three years preceding symptom onset linked to increased risk
Friday, February 28, 2014

Review Examines Incretin-Based Drug, Pancreatic Safety Link
Extensive review of trials, studies by FDA, EMA find data do not support causal association
Thursday, February 27, 2014

Vancomycin-Resistant Group B Streptococci Identified
Isolates from patients show decreased vancomycin susceptibility, with distinct resistance patterns
Wednesday, February 26, 2014

Cocaine Use Doesn't Raise In-Hospital Mortality With MI
Cocaine-positive MI patients are younger, mainly men, with fewer cardiovascular risk factors
Wednesday, February 26, 2014

Not All Acute Coronary Syndrome Patients Get Appropriate Tx
About one in five not receiving angiotensin-converting enzyme inhibitors, receptor blockers per guidelines
Wednesday, February 26, 2014

Doctors Pleased With Congress' Medicare Payment Agreement
Repeal of SGR marks transition to value and quality-based reimbursement
Tuesday, February 25, 2014

MMR Vaccine Timing, Sequencing Tied to Fewer Hospitalizations
Children receiving third DTaP-IPV-Hib after MMR have higher rate of infectious disease admission
Tuesday, February 25, 2014

Children's Behavior Problems Tied to In Utero Acetaminophen
Higher risk seen for ADHD-like behavioral problems and hyperkinetic disorders
Tuesday, February 25, 2014

Doctors Slower to Prescribe HTN Meds to Younger Patients
Study found age was a factor in how quickly patients got treatment
Tuesday, February 25, 2014

More Than Seven Million Patient Record Breaches in 2013
Breaches of protected health information up 137.7 percent; most breaches due to theft
Tuesday, February 25, 2014

Research Agenda Developed for Teen Antipsychotic Rx Use
Second prioritized research agenda focuses on management of ductal carcinoma in situ
Tuesday, February 25, 2014

In Nonvalvular A-Fib, AAN Urges Routine Anticoagulation
Specific patient considerations will influence anticoagulant selection, AAN guideline says
Tuesday, February 25, 2014

Review: Antibiotics Don't Avert Otitis, Pneumonia in Children
No strong evidence for preventive effect in children with undifferentiated acute respiratory infections
Tuesday, February 25, 2014

Adjuvant High-Dose Vitamin D3 Beneficial in Urticaria
Significant decrease in total urticaria symptom severity by week 12 with high-dose supplement
Tuesday, February 25, 2014

HPV Vaccination Reduces Cervical Lesion Risk at Population Level
Cohort study in Denmark shows reduction in risk of atypia, CIN grade 2/3 among vaccinated
Tuesday, February 25, 2014

USPSTF: Evidence Lacking for Vitamin Prevention of CVD, CA
Final recommendation shows insufficient evidence to assess benefits and harms of multivitamins
Monday, February 24, 2014

FDA to Step Up Oversight of Indian Drug Makers
More inspectors planned as India emerges as growing source of pharmaceuticals
Monday, February 24, 2014

Patient-Centered Medical Homes Cut Care Costs
Findings based on analysis of 20 recently published peer-reviewed studies
Friday, February 21, 2014

Rituximab Doesn't Alleviate Sjögren Symptoms at Week 24
Some symptoms of primary Sjögren syndrome alleviated at earlier time points with rituximab
Friday, February 21, 2014

Concurrent Opioid Prescribing by Multiple Providers Common
More than three-quarters of Medicare beneficiaries with four or more providers have concurrent rx
Thursday, February 20, 2014

Tamoxifen Found in Samples of Dietary Supplement
Tamoxifen identified in three of four samples of dietary supplement, Esto Suppress
Thursday, February 20, 2014

>14 Percent of Women Given an Opioid Rx During Pregnancy
Opioid dispensation split fairly evenly during all three trimesters, but highest in third trimester
Thursday, February 20, 2014

Before Implementation, Full EHR Cost Needs Consideration
Costs of training, facilities, infrastructure and variables affecting these categories must be ID'd
Wednesday, February 19, 2014

Eardrops Most Effective in Tympanostomy-Tube Otorrhea
Outcomes better than treatment with oral antibiotics or observation
Wednesday, February 19, 2014

'Talking' Medical Devices, Apps Continue to Evolve
Can help people manage their conditions, function in emergencies, keep doctors informed
Wednesday, February 19, 2014

Compression Device Noninferior to Meds Post-Arthroplasty
Noninferior efficacy in venous thromboembolism prevention versus pharmacological protocol
Tuesday, February 18, 2014

Citalopram Cuts Agitation Associated With Alzheimer's
Cognitive and cardiac adverse effects may limit citalopram dosage maximums per day
Tuesday, February 18, 2014

Online Ratings Do Affect Patient Choice of Physician
Whether or not physician accepts insurance plan remains top decider in selecting physician
Tuesday, February 18, 2014

Earlier Tx Shortens Duration of Febrile Seizures in Children
Researchers note that seizures rarely stop spontaneously
Tuesday, February 18, 2014

Lower-Intensity Statin Combo Rx Option for Resistant Patients
Can be used instead of higher-intensity treatment for some high-risk patients
Monday, February 17, 2014

Most Patients Hospitalized With Flu Are Unvaccinated
23.6 percent of hospitalized patients vaccinated; rate even lower among those requiring ICU care
Monday, February 17, 2014

ASA: Study Shows No Benefit of Magnesium Soon After Stroke
Disability level similar after magnesium or saline treatment
Friday, February 14, 2014

Clonidine Premedication Relieves Post-Op Pain in Children
Premedication at adequate dosage seems likely to reduce analgesia requirements after surgery
Friday, February 14, 2014

CMS Extends 2013 Meaningful Use Attestation Deadline
Deadline extended, allowing providers to submit data for 2013 reporting year through March 31, 2014
Thursday, February 13, 2014

Congress Agrees on Legislation to Replace SGR Formula
New legislation emphasizes quality over quantity, with merit-based incentives
Thursday, February 13, 2014

ICD-10 Implementation Likely to Be Financial Disaster
Letter from AMA to HHS voices concerns over higher-than-expected costs of implementation
Thursday, February 13, 2014

ASA: Despite Access, Few in U.S. Get Recommended Stroke Care
Most have geographic access to acute stroke care, but treatment rates remain low
Thursday, February 13, 2014

Affordable Care Act Enrollment Nears 3.3 Million
About one-quarter of those signed up are now young adults, report shows
Thursday, February 13, 2014

Fewer Doses of HPV Vaccine Still Protect Against Condyloma
Two doses rather than the recommended three still protective
Thursday, February 13, 2014

Pregabalin Treatment Effective in Restless Legs Syndrome
Improved treatment outcomes versus placebo; lower augmentation than with 0.5 mg pramipexole
Thursday, February 13, 2014

U.S. Officials Target Escalating Drug Overdoses
Deadly epidemic is driven by abuse of narcotic painkillers and heroin
Wednesday, February 12, 2014

ASA: Acute Cocaine Use Ups Ischemic Stroke Risk
Strong correlation between reported cocaine use in 24 hours prior to stroke and ischemic stroke
Wednesday, February 12, 2014

FDA to Investigate Saxagliptin for Possible Heart Failure Risk
Marketed as Onglyza and Kombiglyze XR, appears to have no effect on heart attack or stroke risk
Tuesday, February 11, 2014

FDA Panel Sees No Heart-Safety Advantage With Naproxen
Some studies had suggested naproxen might pose less of a threat than other NSAIDs
Tuesday, February 11, 2014

Mid-Sized Companies Get Extra Year to Comply With ACA
Government sets up new deadlines for three sizes of companies
Tuesday, February 11, 2014

Guidelines Issued for Managing Hospital Medicine Groups
Assessment guide comprises 10 principles and 47 characteristics for effective HMG management
Tuesday, February 11, 2014

FDA Advisers Revisit Heart Risks Posed by NSAIDs
Studies suggest naproxen may pose less of a threat
Monday, February 10, 2014

New Rule Allows Patients to Access Laboratory Test Results
Final rule allows patient or personal representative to access results directly from the laboratory
Monday, February 10, 2014

Merck to Offer $100 Million Settlement in NuvaRing Lawsuits
Merck will pay $100 million to settle thousands of lawsuits over NuvaRing birth control device
Monday, February 10, 2014

HPV Vaccines Don't Change Behaviors in Young Women
No engagement in riskier sexual behavior seen following HPV vaccination
Friday, February 07, 2014

Drugs Increasingly Detected in Fatally Injured Drivers
Positive results for non-alcohol drugs rose from 16.6 to 28.3 percent from 1999 to 2010
Friday, February 07, 2014

Racial/Ethnic Differences in CHD Outcomes Not Due to Statins
Differences attributed to demographics, comorbidities; not differential statin prescribing
Friday, February 07, 2014

Daily Aspirin May Guard Against Ovarian Cancer
Study of almost 20,000 women found the drug lowered risk by 20 percent
Friday, February 07, 2014

Physicians Need to Be Prepared to Talk Antibiotics
Specific diagnosis, whether viral or bacterial, will aid conversation with patients or their parents
Thursday, February 06, 2014

ICD-10 Transition May Impact Practice Cash Flow
Organizations may not yet understand the impact that ICD-10 will have on their businesses
Wednesday, February 05, 2014

FDA: There's Still Time for Patients to Get a Flu Shot
Younger adults seem at risk this year, FDA says
Wednesday, February 05, 2014

NSAID Exposure Not Linked to Risk of Spontaneous Abortion
No risk for specific drugs, with the exception of significantly increased risk for indomethacin
Wednesday, February 05, 2014

CVS Caremark to Stop Selling Tobacco Products
Says sale of cigarettes is inconsistent with a pharmacy's mission
Wednesday, February 05, 2014

New Guidelines Issued for Acute Otitis Externa Management
Updated recommendations include analgesic treatment for pain; not using antimicrobials for initial tx
Wednesday, February 05, 2014

FDA Approves Continuous Glucose Monitoring System for Children
However, device doesn't perform as well in children as in adults, FDA says
Tuesday, February 04, 2014

Testosterone Use Ups Risk of Myocardial Infarction in Men
Risk is higher in younger men with pre-existing heart disease and in older men
Tuesday, February 04, 2014

Declines in Antibiotic Use in Children May Have Plateaued
Large declines in prescribing rates seen in the early 2000s; trend attenuated by end of decade
Tuesday, February 04, 2014

Online Medical Records Trump Colleagues As Docs' Info Source
Doctors are exposed to online medical records, prescribing software more than 200 times/year
Tuesday, February 04, 2014

Medicating Drivers for ADHD May Cut Risk of Traffic Accidents
Significant link observed for male, but not female, drivers with attention-deficit/hyperactivity disorder
Tuesday, February 04, 2014

Hospital Staff Training Improves Palliative Care Processes
In-hospital intervention leads to improvements in quality end points for end-of-life care
Monday, February 03, 2014

FDA Will Review Safety of Testosterone Therapy
Agency pointed to recent studies citing possible heightened heart risk tied to the treatments
Monday, February 03, 2014

Health Reform Differs Across States: Report
Five states play no role in federal marketplace, Medicaid expansion, or insurance reform
Monday, February 03, 2014

Postmenopausal Hormone Rx May Cut Risk for Glaucoma
Findings significant with estrogen-only postmenopausal hormone treatment
Friday, January 31, 2014

AAP Approves Childhood Immunization Schedules for 2014
Schedules follow same format as last year, with single schedule for children aged 0 to 18 years
Friday, January 31, 2014

Inappropriate Use of Antibiotics in ERs Remains High for Adults
Inappropriate use for respiratory tract infection down from 2001 to 2010 for children, not adults
Thursday, January 30, 2014

Androgen Deprivation Therapy Can Take Emotional Toll
But no clinically meaningful decline in quality of life seen in prostate cancer patients at 24 months
Thursday, January 30, 2014

Businesses Urge Change to ACA's Insurance Mandate
House panel members spar over claim that provision of health-reform law is a 'job killer'
Wednesday, January 29, 2014

ASA Issues Top Five Choosing Wisely Recommendations
Recommendations relate to pain medicine; include guidance for opioid use for non-cancer pain
Wednesday, January 29, 2014

Handwashing Appears Best in Prevention of Common Cold
Best evidence for prevention supports handwashing, zinc supplements, but evidence often poor quality
Wednesday, January 29, 2014

Insurance Eligibility Headaches Expected With ACA
Practices expected to face influx of newly insured patients, possibly without insurance ID cards
Tuesday, January 28, 2014

Role of Vitamin D in Disease Prevention Is Uncertain
Meta-analysis shows that widespread supplementation does not improve health outcomes
Tuesday, January 28, 2014

FDA Panel Considers First Pill for Ragweed Allergy
Placed under the tongue, it helps the body immunize itself against the offending plant
Tuesday, January 28, 2014

Hormone Therapy Linked to Reduced Arthroplasty Revision
HRT use for ≥6 months tied to almost 40 percent decrease in hip/knee replacement revision rates
Monday, January 27, 2014

Stimulant, Antipsychotic Combo Improves Aggressive Behavior
Improvement for children with ADHD, aggressive disorder with stimulant, parent training, risperidone
Friday, January 24, 2014

Sickle Cell Trait Affects Dosing of Anemia Medications in Dialysis
Sickle cell or hemoglobin C trait may mean higher doses of erythropoiesis-stimulating agents needed
Friday, January 24, 2014

Phase 3 Studies Fail to Show Benefit of Drugs in Alzheimer's
No improvement in cognition in randomized trials of bapineuzumab and solanezumab
Wednesday, January 22, 2014

Legitimacy of Publishing Pharma-Funded Research Queried
Researchers present arguments for and against stopping publication of industry-funded research
Wednesday, January 22, 2014

Chinese Herb Capsule May Help Reduce Progression to Diabetes
Tianqi mixture of 10 herbs safe and effective for reducing incidence of T2DM in subjects with IGT
Wednesday, January 22, 2014

Pediatric AOM Costs Health Care System ~$2.88 Billion Annually
Children with acute otitis media have increased outpatient health care costs, patient medication costs
Wednesday, January 22, 2014

ACA Impact on Primary Practice May Depend on Location
Practices in states with expanded Medicaid may see more new, chronically ill patients
Tuesday, January 21, 2014

Researchers Examine FDA Decision Making Processes
Analyses show variation in quality-of-evidence; reliance on premarket approval; reasons for delays
Tuesday, January 21, 2014

More Federal Funding of Health Centers Mitigates Access Issues
Findings among low-income, uninsured adults from 2002 to 2007
Tuesday, January 21, 2014

Medication Synchronization Program Ups Adherence
Community pharmacy-based program projects increase of 20 med fills per patient per year
Tuesday, January 21, 2014

Multiple Medications Increase Odds of Hospital Admission
Link modified by number of long-term conditions, with reduced effect for multiple conditions
Tuesday, January 21, 2014

AMA Launches Online Resource to Guide HTN Management
Microsite offers access to new guideline, editorial addressing guideline, relevant medical articles
Monday, January 20, 2014

Statin Use Linked to Reduced Delirium in ICU Patients
Statin administration linked to increased odds of patient being assessed as free of delirium
Monday, January 20, 2014

FDA Warns of Fires From Some Cryogenic Wart Removers
Don't use flammable products near candles, hair appliances, agency says
Thursday, January 16, 2014

State Insurance Marketplaces Boost Outreach Efforts
Educating the uninsured, especially young adults, is a priority, executives say
Thursday, January 16, 2014

Reliable Emotion Words ID'd to Assess Patient Experience
Word set can be used in experience-based design questionnaires for patient care
Thursday, January 16, 2014

NCPA: Access to Controlled Substances Often Delayed
Most pharmacists report three or more delays in past 18 months, usually lasting at least one week
Thursday, January 16, 2014

Pritelivir Safe, Effective for Genital HSV-2 Infection
Dose-dependent reduction seen in rate of genital HSV shedding and days with lesions
Wednesday, January 15, 2014

FDA Warns Against Rx With High Levels of Acetaminophen
Agency recommends that physicians cease prescriptions of drugs in excess of 325 mg
Wednesday, January 15, 2014

Beliefs About Safety May Spark E-Cigarette Use in Young Adults
Those who believe e-cigarettes are less harmful are more likely to experiment with them
Wednesday, January 15, 2014

Risk of Intussusception Still Up After New Rotavirus Vaccination
However, two studies show that risk is lower than that seen with previous vaccines
Tuesday, January 14, 2014

Green Tea May Interfere With Antihypertensive
Small, early study found reduced blood levels of nadolol among green tea drinkers
Tuesday, January 14, 2014

Merck Recalls Cholesterol Drug Liptruzet
Company issues recall due to defects in product packaging
Tuesday, January 14, 2014

More Than Two Million People Have Signed Up for ACA Coverage
Nearly one in four are young adults, a demographic key to the program's success
Tuesday, January 14, 2014

Wednesday Is Deadline for Feb. 1 Coverage Under ACA
Uninsured Americans can still sign up for 2014 coverage through March 31
Tuesday, January 14, 2014

Testosterone Often Initiated in Men With Normal Levels
Dramatic increase in testing and supplementation occurred in the last decade in the United States
Monday, January 13, 2014

Suicide Risk Equal for Children Taking Single Antidepressant
Users of multiple antidepressants concomitantly have increased risk for suicide attempt
Monday, January 13, 2014

CMS: New Rule Proposed for Contract Year 2015
Rule will strengthen protections, up health care quality, cut costs in Medicare Advantage, Part D
Monday, January 13, 2014

ACP Introduces Free 'High Value Care' Case Studies
Five topics in interactive case studies include avoiding unnecessary testing, safe prescribing
Friday, January 10, 2014

Female Conveners Up Number of Women at Scientific Symposia
Number of invited female speakers increases by 72 percent compared with all-male conveners
Friday, January 10, 2014

CMS: Low Growth for National Health Expenditures in 2012
Low growth in private health insurance spending, Medicare and Medicaid spending
Friday, January 10, 2014

EHR Use Linked to Doc-Reported Enhanced Patient Care
Use of EHRs that meet Meaningful Use criteria, longer EHR experience linked to reported benefits
Friday, January 10, 2014

Most Ped OTC Liquid Med Labels Adhere to FDA Dosing Guidelines
Second study shows that child OTC analgesic use is linked to maternal use of OTC analgesics
Thursday, January 09, 2014

Extended Varenicline Use Ups Smoking Abstinence Rates
Findings in mentally ill patients achieving initial smoking abstinence with 12-week treatment
Thursday, January 09, 2014

Impact of In Utero Epilepsy Med Exposure Studied in Children
Superior language, motor development for levetiracetam versus sodium valproate exposure
Thursday, January 09, 2014

Drug Labeling Linked to Drug, Placebo Efficacy in Migraine
Effect of placebo and active drug increased with progressively positive drug information
Thursday, January 09, 2014

No Long-Term Benefit Seen for Smoking Cessation Combo Rx
Although combination varenicline-bupropion initially more effective than varenicline alone
Wednesday, January 08, 2014

FDA Approves Farxiga for Type 2 Diabetes
To be used along with proper diet and exercise
Wednesday, January 08, 2014

Liquid Tamiflu for Children in Short Supply
Shortage should be resolved in week; Tamiflu capsules, flu shots widely available, U.S. officials say
Wednesday, January 08, 2014

Smoking Rates Still Low for Most Health Care Professionals
Pattern persists with rates lowest in physicians (2 percent), highest in LPNs (25 percent)
Wednesday, January 08, 2014

Herpes Zoster Is Risk Factor for Stroke in Young Adults
Stroke, transient ischemic attack, MI increased in cases whose herpes zoster occurred before age 40
Monday, January 06, 2014

Obama Administration Stands by Contraception Rule
U.S. Justice Department resists court order exempting nuns from ACA birth control rule
Monday, January 06, 2014

CDC Addresses Burden, Threat of Antibiotic Resistance
One of most urgent threats is C. difficile; causes a minimum of 250,000 illnesses per year
Monday, January 06, 2014

Guidelines for Management of Menopausal Symptoms Issued
Care should be personalized; lowest effective dose recommended for shortest time to relieve symptoms
Monday, January 06, 2014

AMA Details Top Five Federal Issues for 2014
Issues include repeal of SGR, full implementation of ACA, roll out of ICD-10 code set
Monday, January 06, 2014

Over 100 New Accountable Care Organizations Formed
New ACOs will provide high-quality coordinated care access for ~1.5 million Medicare beneficiaries
Friday, January 03, 2014

Doctors Discuss Use of MenB Vaccine at Princeton University
Use of experimental vaccine has called into question decision not to vaccinate more widely
Friday, January 03, 2014

Warfarin Initiation Negatively Linked to Stroke in A-Fib Patients
Risk highest in the 30 days after initiating treatment
Friday, January 03, 2014

Increasing BMI Tied to Steady Increase in Health Care Costs
Cardiovascular disease was associated with the largest dollar increase per unit increase in BMI
Thursday, January 02, 2014

CDC: Updated Guidance for HBV Vaccination for Health Workers
All should be vaccinated and undergo serologic testing
Thursday, January 02, 2014

Usage, Cost of Antibiotics for Children Higher in U.S. Versus U.K.
For young children, annual cost of antibiotics more than five times higher in United States
Thursday, January 02, 2014

Pharmacies Often Misinform Young Females About Plan B
Misinformation given to adolescents partly due to confusion about changing regulations
Thursday, January 02, 2014

Alpha Tocopherol Seems Beneficial in Alzheimer's
Slower functional decline and least increase in caregiver burden for those taking alpha tocopherol
Thursday, January 02, 2014

Troubled Launch of ACA Tops Health News for 2013
Angelina Jolie's double mastectomy, new heart care guidelines also made headlines
Tuesday, December 31, 2013

Extra Steps Urged for Regulating Compounding Pharmacies
Drug Quality and Security Act is a start, but leaves several gaps that need filling
Monday, December 30, 2013

Landmark ADHD Study Backed Drugs Over Therapy at a Cost
Children denied counseling may have lost out, experts say
Monday, December 30, 2013

Alendronate Reduces Adjacent-Level Vertebral Fractures
For females with osteoporosis, annual rate 1.2 percent with alendronate, 2.5 percent with placebo
Monday, December 30, 2013

Nortriptyline Doesn't Provide Gastroparesis Symptom Relief
Findings based on 15-week trial comparing nortriptyline to placebo for idiopathic gastroparesis
Monday, December 30, 2013

Inosine Safe, Effective for Raising Urate Levels in Parkinson's
Serum and cerebrospinal fluid urate levels raised with inosine treatment in early Parkinson's
Monday, December 30, 2013

Surge in Federal Health Insurance Exchange Enrollments
More than one million people have signed up for coverage under Affordable Care Act
Monday, December 30, 2013

Fewer Opioid Treatment Centers Offering HIV, STI Testing
For-profit centers, which increased in number from 2000 to 2011, saw greatest testing declines
Friday, December 27, 2013

Performance-Enhancing Drug Use Widespread in U.S.
Use of PEDs more widespread than thought; can have adverse health consequences
Friday, December 27, 2013

ACA Success Hinges on Young Adult Enrollment
Uncertainty lingers on the willingness, ability of young adults to enroll in marketplaces, Medicaid
Thursday, December 26, 2013

Impact of Planned Medicaid Expansion Discussed
Could help close substantial gaps in U.S. health care safety net if all states elect to expand
Thursday, December 26, 2013

Testosterone May Undermine Flu Vaccine Effectiveness for Men
Poorer response to flu vaccine in men linked to testosterone-regulated gene cluster
Thursday, December 26, 2013

HIV Life Expectancy Similar to General Population
Those receiving combination antiretroviral therapy can live into their 70s
Thursday, December 26, 2013

Public Tends to Follow Celebrities Even on Medical Issues
Health care providers need to take phenomenon seriously and counter bogus advice
Monday, December 23, 2013

ACEI/ARB Rx Safe, Beneficial in Advanced Chronic Kidney Disease
Both ACEI/ARBs linked to lower risk for long-term dialysis, death with advanced kidney disease
Monday, December 23, 2013

High Patient Satisfaction With Patient-Centered Medical Homes
Positive reports of patient-centered measures correlate with reports of high-quality care
Friday, December 20, 2013

New Rule May Exempt Many From Health Plan Penalty
People in cancelled policies can buy coverage under last-minute revision to ACA
Friday, December 20, 2013

Evidence-Based Guidelines Issued for Hypertension Management
BP goal of 150/90 mm Hg for patients aged 60 or older; 140/90 mm Hg for younger patients
Friday, December 20, 2013

Modeling Study: Similar Effects for Statin or Apple a Day
Nutritional and pharmaceutical approaches have similar reductions in vascular mortality
Thursday, December 19, 2013

Pre-Op Depression Linked to Narcotic Use Before Spinal Sx
Patients categorized as depressed or anxious have higher preoperative narcotic use
Thursday, December 19, 2013

Antiviral Treatment Benefits Patients With Diabetes
HCV treatment may lower risk of end-stage renal disease, stroke, acute coronary syndrome
Thursday, December 19, 2013

FDA Approves New Drug to Treat COPD
Inhaled medication combines umeclidinium and vilanterol
Wednesday, December 18, 2013

Maternal Antidepressant Use Not Significantly Linked to Autism
No significant increase in offspring autism risk linked to SSRI use during pregnancy
Wednesday, December 18, 2013

Exercise Ups Sexual Function in Women on Antidepressants
Improves sexual desire and global sexual function
Wednesday, December 18, 2013

Metformin Tied to Modest BMI Reduction in Obese Children
Review provides moderate-strength evidence of reduction in BMI from baseline at six months
Wednesday, December 18, 2013

Few Residency Programs Teach Cost-Conscious Medicine
Despite perceived role in limiting increasing health care costs, few residents know costs of tests
Wednesday, December 18, 2013

CDC Highlights Achievements of 2013, Goals for 2014
Top achievements include getting >100,000 smokers to quit; cut in health care facility-linked infections
Wednesday, December 18, 2013

Funding for Medical Communication Firms Analyzed
May receive substantial support from pharmaceutical, medical device companies
Tuesday, December 17, 2013

GlaxoSmithKline to End Payments to Prescribing Doctors
Pharmaceutical giant first drug maker to adopt such a policy, report says
Tuesday, December 17, 2013

Oral Multivitamin, Multimineral Safe, Not Effective After MI
Findings in cohort of older patients with history of myocardial infarction
Tuesday, December 17, 2013

Physician Access Challenges Up for Those With Public Insurance
Second study notes that 14.6 percent of people in U.S. were uninsured in first half of 2013
Tuesday, December 17, 2013

FDA Questions Effectiveness, Safety of Antibacterial Soap
Proposed rule requires manufacturers to submit trial data showing benefit versus regular soap
Tuesday, December 17, 2013

Physicians Conclude Multivitamins Should Not Be Used
Despite evidence of no benefit or possible harm, multivitamin use increasing among U.S. adults
Tuesday, December 17, 2013

Many Physicians Will Stop Practicing Due to ACA
Nearly three-quarters believe that ACA will negatively impact compensation
Tuesday, December 17, 2013

No Cognitive Benefit for Long-Term Multivitamin Supplement
Findings in cohort of older male physicians randomized to multivitamin or placebo
Monday, December 16, 2013

Bills for SGR Repeal Pass Senate, House Committees
Near unanimous bipartisan votes from Senate Finance, House Ways and Means Committees
Monday, December 16, 2013

CDC: Flu Vaccine Reduced Adverse Outcomes by 17 Percent
Greater number of serious outcomes averted in 2012-2013 compared with previous flu seasons
Monday, December 16, 2013

New Rule Tweaks Affordable Care Act Deadline
Insurers pressed for flexibility on premium payments, coverage
Friday, December 13, 2013

ASCO Report Highlights Progress Against Cancer in Last Year
Report features 76 studies; highlights new approaches to cancer care, new treatments
Friday, December 13, 2013

Study Quantifies Male Dominance in Scientific Production
Women account for <30 percent of fractionalized authorships; similar pattern in first authorships
Friday, December 13, 2013

SABCS: Exercise Eases Aromatase Inhibitor-Induced Arthralgia
Survivors experience greater decrease in worst joint pain scores, joint pain severity with exercise
Thursday, December 12, 2013

FDA Approves Generic Cymbalta (Duloxetine)
Labeling states drug/other antidepressants could up risk of suicidal thoughts/action
Thursday, December 12, 2013

New Inactivated Quadrivalent Flu Vaccine Found Efficacious in Kids
QIV efficacious in preventing influenza, reducing attack rate in moderate-to-severe disease
Wednesday, December 11, 2013

Factors in Choice of Opioid for Abuse Analyzed
Three-quarters of opioid-dependent individuals use oxycodone or hydrocodone
Wednesday, December 11, 2013

No Serious Heart Risks With Smoking Cessation Therapies
Meta-analysis shows protective effect of bupropion for major adverse cardiovascular events
Wednesday, December 11, 2013

Recommendations Issued to Prevent VTE in Maternal Patients
Include assessment with automated scoring system, provision of appropriate information on discharge
Wednesday, December 11, 2013

CDC: Health Insurance Among Young Increased After ACA
Extension of dependent health coverage in 2010 has increased private coverage, decreased gaps
Wednesday, December 11, 2013

CMS Finalizes 2014 Physician Payment Rates, Policies
Include provision to support care management outside of routine office interaction
Monday, December 09, 2013

Issues Surround Hospital Readmissions Reduction Program
Issues include methodology for determining expected readmission rates, computing penalties
Friday, December 06, 2013

Serum 25(OH)D Marker of Ill Health, Not Causative Agent
Links seen between 25(OH)D concentration and health outcomes; supplementation has little effect
Friday, December 06, 2013

Final Rule Aims to Lower Costs, Simplify Outpatient Payments
CMS introducing single outpatient visit code; payments will be packaged into single payment
Friday, December 06, 2013

Most Teens With Psychiatric Disorders Don't Receive Care
Black youth less likely to get specialty mental health, general medical services for mental disorders
Thursday, December 05, 2013

CDC: More People With Asthma Getting Flu Shots
However, vaccination rates still below goal for all
Thursday, December 05, 2013

Handoff Program Cuts Medical Errors, Adverse Events
Multifaceted program at children's hospital also increases physician time spent at patient bedside
Thursday, December 05, 2013

AMA's RUC Committee to Work on Improving Transparency
New means to be used to survey physicians to better determine value of procedures
Wednesday, December 04, 2013

Results Mixed for Liberal Transfusions in Heart Disease
Outcome effects of aggressive protocols in heart disease patients with anemia mixed
Wednesday, December 04, 2013

CDC: Over 6 Percent of Teens Take Psychotropic Meds
Antidepressants and ADHD drugs are most commonly used psychotropic medications in teens
Wednesday, December 04, 2013

Investment Program Can Cut Global Health Disparities by 2035
Framework focuses on reducing maternal, child, infectious deaths; 10 million deaths averted by 2035
Wednesday, December 04, 2013

Recent Rapid Increase in Mental Health Care for Youth
More rapid increase in visits resulting in mental disorder diagnosis for youth versus adults
Tuesday, December 03, 2013

Nonantibiotic Prophylaxis Can Benefit Recurrent UTI
Meta-analysis includes oral immunostimulant OM-89, estrogens, cranberries, acupuncture
Tuesday, December 03, 2013

FDA Starts Regulating Compounding Pharmacies
New process designed to make specialty drugs safer for patients
Tuesday, December 03, 2013

Comorbidities, Meds Factor Into Recurrent Syncope
Certain co-existing conditions, use of multiple medications that cause orthostatic hypotension up risk
Monday, December 02, 2013

Spatiotemporal Analysis Emphasizes Value of Vaccination
Analysis of disease trends since 1888 shows 103 million cases of contagious disease prevented
Wednesday, November 27, 2013

Telemedicine in Rural ER Tied to Fewer Physician Rx Errors
Findings based on consults for seriously ill, injured children in rural emergency departments
Wednesday, November 27, 2013

Practices Should Start Preparing for Transition to ICD-10
Point-person should be appointed within practice; staff training also recommended
Tuesday, November 26, 2013

Oral Fluoroquinolone Use Not Linked to Retinal Detachment
Findings in large Danish cohort for current use, recent use, past use, distant use
Tuesday, November 26, 2013

Optimal Testosterone Levels Tied to Survival in Older Men
Men with non-optimal levels tend to have higher all-cause, ischemic heart disease mortality
Tuesday, November 26, 2013

FDA Approves H5N1 Avian Influenza Vaccine
To supplement National Stockpile, not intended for commercial availability
Monday, November 25, 2013

FDA to Lift Restrictions on Diabetes Drug Avandia
Not all experts are happy with granting wider access to the troubled medication, however
Monday, November 25, 2013

Testosterone Therapy Doesn't Worsen Urinary Symptoms
About 30 percent of men experience an AUA symptoms index improvement of 3 or more points
Monday, November 25, 2013

Nebulizers Deliver Less Than Half of Prescribed Asthma Rx in Kids
Dose of prescribed corticosteroids inhaled from nebulizer varies with drug formulation
Monday, November 25, 2013

Antiviral Therapy Helps Children Critically Ill With Flu
Prompt treatment with neuraminidase inhibitors may improve survival
Monday, November 25, 2013

American Medical Groups Protesting Physician Cuts
Action follows mass cancellations of physicians in Medicare Advantage plans in many states
Monday, November 25, 2013

CDC: More Than One in 10 Kids Diagnosed With ADHD
Nearly one in five currently diagnosed with ADHD not receiving medication, counseling
Monday, November 25, 2013

White House Extends Enrollment Deadline for Health Insurance
And HealthCare.gov website capacity to double by end of month, Obama adviser pledges
Friday, November 22, 2013

Daily Text Messages Improve Diabetes Outcomes
Diabetes control and medication adherence improve; fewer trips to the emergency room
Friday, November 22, 2013

Personalized Pharmacist-Led Care Ups Med Adherence in ACS
Findings in year after discharge for patients hospitalized with acute coronary syndrome
Thursday, November 21, 2013

CDC Report: Health Disparities Persist in America
CDC finds race, sex, education, location, and wealth among key factors in these inequalities
Thursday, November 21, 2013

Calcium, Vitamin D Up BMD for Patients on Antiepileptic Drugs
Added benefits seen with addition of risedronate
Wednesday, November 20, 2013

More Than Half of Hospitalized Patients Given Opioids
Relative risk of severe opioid-related adverse event up at hospitals with higher opioid prescribing
Wednesday, November 20, 2013

Health Care Frustration Higher in U.S. Than Other Countries
Majority of U.S. adults feel that the health care system needs to undergo fundamental changes
Tuesday, November 19, 2013

AHA: Taking Aspirin at Bedtime Cuts Platelet Reactivity
Based on randomized crossover trial, taking aspirin at bedtime better than the morning
Tuesday, November 19, 2013

Effect of Statins on Cognitive Function Unclear
Despite FDA warning, further evidence is needed to establish an effect
Tuesday, November 19, 2013

Some Doctors Challenge New Statin Guidelines
They say too many people would get statins; heart groups defend the recommendations
Monday, November 18, 2013

AHA: Text Messaging Improves Antiplatelet Adherence
Text messaging reminders and health education up percent of correct doses taken, doses on schedule
Monday, November 18, 2013

AAP/CDC Update Antibiotic Guidance for Pediatric URIs
Use of stringent diagnostic criteria is advised to distinguish between viral and bacterial infections
Monday, November 18, 2013

Global Efforts Needed to Curb Antibiotic Resistance
National task forces should act in areas such as surveillance, treatment guidelines, education
Monday, November 18, 2013

FDA Requests Safety Measures for Topical Antiseptics
Labeling and packaging changes meant to reduce risk of infection
Friday, November 15, 2013

Obama Nominates Health Care Law Backer to Be Surgeon General
Vivek Murthy, M.D., was an early supporter and advocate for the Affordable Care Act
Friday, November 15, 2013

Obama: You Can Keep Your Health Plan (for a Year)
Proposed change comes amid intense bipartisan pressure for a health-law fix
Thursday, November 14, 2013

Obama Signs Bill to Encourage Schools to Stock Epinephrine
Financial incentive for states to maintain epinephrine supply in schools
Thursday, November 14, 2013

New Guidelines Issued for Cholesterol Management
Four major statin benefit groups identified for whom risk reduction outweighs risk of adverse events
Thursday, November 14, 2013

Health Care Enrollments Fall Far Short of White House Estimates
Fewer than 27,000 people signed up for insurance through federal exchange in October, officials report
Thursday, November 14, 2013

No Promises on Nov. 30 ACA Website Fix: U.S. Tech Chief
Pressure mounts for solutions to health-law problems as deadline nears
Thursday, November 14, 2013

AAPS: Intravaginal Ring Offers Dual Protection for 90 Days
Ring contains drugs to prevent HIV transmission and pregnancy
Wednesday, November 13, 2013

Population Aging Crisis May Have Been Overestimated
Decrease in dependency with threshold as remaining life expectancy of ≤15 years
Wednesday, November 13, 2013

Many Would Give Health Plans Private Info to Save Money: Poll
Experts question whether people responding to Harris/HealthDay poll understand broader impact
Wednesday, November 13, 2013

Initial Health-Plan Enrollment Falls Below Expectations
Early reports find federal and state insurance exchanges attracted low numbers
Tuesday, November 12, 2013

Thromboembolism Prophylaxis Underused After C-Section
Despite large increases in adoption, fewer than half of those undergoing cesarean receive prophylaxis
Tuesday, November 12, 2013

Many Americans Want Docs to Help Explain Genetic Tests
Even though some companies offer testing directly to the consumer
Tuesday, November 12, 2013

Analysis Describes Economic Anatomy of U.S. Health Care
Despite increased resources for U.S. health care, health metrics show U.S. trailing peer nations
Tuesday, November 12, 2013

USPSTF: Lack of Evidence for Vitamins for CVD, CA Prevention
Insufficient evidence to weigh the benefits and harms of multivitamins for primary prevention
Tuesday, November 12, 2013

ASN: ACE Inhibitor Plus ARB No Benefit in Diabetic Nephropathy
Increased risk of hyperkalemia and acute kidney injury; safety concerns resulted in early end to trial
Monday, November 11, 2013

ASN: Calcium-Channel Blocker-Antibiotic Combo Impacts Kidneys
Risk of hospitalization for acute kidney injury up for clarithromycin plus calcium-channel blocker
Monday, November 11, 2013

Obama 'Sorry' Some People Losing Health Coverage
Website repairs continue amid continued scrutiny of Affordable Care Act
Friday, November 08, 2013

ACAAI: Gelatin Allergy Can Cause Reaction to Flu Shot
Case report describes 4-year-old with adverse response within 15 minutes of receiving flu shot
Friday, November 08, 2013

Telemedicine Represents Enhanced Care Model
Uses technology to provide better health care and more reach, but legal and other concerns exist
Thursday, November 07, 2013

FDA to Ban Trans Fats in Foods
Trans fats linked to cardiovascular health
Thursday, November 07, 2013

Postdiagnostic Statin Use Cuts Mortality in Prostate Cancer
Stronger effect on prostate cancer-linked, all-cause mortality for those with prediagnostic use
Thursday, November 07, 2013

Amount of Care Similar for Rural, Urban Medicare Users
No difference in amount of health care received or satisfaction with access to care within regions
Thursday, November 07, 2013

Metformin Little Benefit for CHD Patients Without Diabetes
No effect on mean distal carotid intima-media thickness for coronary heart disease patients
Thursday, November 07, 2013

Sebelius on Exchange Website: 'Delay Is Not an Option'
'A couple of hundred' fixes required, she tells Senate committee
Wednesday, November 06, 2013

In CAD, Many Don't Get Optimal Secondary Prevention Med Combo
About one-third don't receive optimal combination; considerable variation by practice
Wednesday, November 06, 2013

Study Raises Questions About Testosterone Rx for 'Low T'
Increased risk of death, MI, stroke in men with low levels who undergo coronary angiography
Tuesday, November 05, 2013

Senators Seek Answers on Health Marketplace Woes
Medicare chief says HealthCare.gov is secure, site operations are improving
Tuesday, November 05, 2013

One Dose of HPV Vaccine Induces Long-Term Antibodies
Levels are lower than multiple doses but remain stable for at least four years
Tuesday, November 05, 2013

Parental Vaccine Acceptance Linked to Provider Communication
Higher odds of resisting recommendations if provider uses participatory versus presumptive format
Monday, November 04, 2013

APHA: Acetaminophen + Light Alcohol Use Up Kidney Injury
Individually, neither light/moderate alcohol consumption nor acetaminophen increase risk
Monday, November 04, 2013

Six People Signed Up on Day One of Federal Exchange Website
By the end of the second day, 248 people had enrolled for coverage, reports say
Friday, November 01, 2013

Proper Metered-Dose Inhaler-Spacer Technique Lacking
Findings among caregivers of urban, minority children with persistent asthma
Friday, November 01, 2013

FDA Announces Moves to Avert Drug Shortages
The FDA's strategic plan for drug shortages involves two major strategies
Thursday, October 31, 2013

Top 100 EHR Systems Sorted by Company Revenue
Some companies offer information about their product and services, but most vendors do not
Thursday, October 31, 2013

Sebelius: 'Hold Me Accountable' for Website 'Debacle'
HHS Secretary insists the troubled online registration site will be fixed by end of November
Wednesday, October 30, 2013

Expedited Review Speeds Approval of New Drugs by FDA
But, drugs are tested in fewer patients, and many questions about safety remain
Wednesday, October 30, 2013

2013 Health Care Quality Report Shows Some Improvements
Medicaid patients are happy with their care; antibiotic overuse still a concern
Wednesday, October 30, 2013

Consultant Offers Tips for Training Staff to Use EHR System
Six tips focus on choosing a team, developing a plan, and scheduling regular training and testing
Tuesday, October 29, 2013

Health Agency Chief Apologizes for Federal Website Woes
Head of CMS insists HealthCare.gov will be much improved within a month
Tuesday, October 29, 2013

One in 10 Teens Using ER Report Non-Rx Opiate, Sedative Use
Correlates of NPOU, NPSU include substance use, drinking and driving, riding with a drinking driver
Monday, October 28, 2013

Clinical Pharmacists Can Aid Patients With Uncontrolled T2DM
Case study involved wheelchair-bound 64-year-old man with hemoglobin A1c of 10 percent
Monday, October 28, 2013

FDA Approves Brain-Imaging Drug for Alzheimer's Detection
Vizamyl is used with PET scan to screen for signs of dementia
Friday, October 25, 2013

FDA Approves Extended-Release Hydrocodone Painkiller
For daily treatment of chronic pain
Friday, October 25, 2013

Most Negative Online Posts Aren't Defamation
Physicians should try to reach out to unhappy posters to fix the problem
Friday, October 25, 2013

Physicians Should Motivate and Retain Top Employees
Article notes that superstar employees are hard to replace
Thursday, October 24, 2013

Penalty Delayed As Federal Exchange Comes Under Fire
Lawmakers demand answers on HealthCare.gov foul-up
Thursday, October 24, 2013

FDA Urges Tighter Controls on Certain Prescription Painkillers
Changes would decrease number of refills before returning to doctor; supplies lasting ≤90 days
Thursday, October 24, 2013

Teen Tdap Vaccines May Cut Infant Pertussis Hospitalization
Rates of hospitalizations lower than expected for three of four years after vaccine implementation
Thursday, October 24, 2013

Mobile Device Use to Aid Rx Common in Nursing Homes
Physicians using mobile devices believe there is a benefit in preventing adverse drug events
Wednesday, October 23, 2013

FDA Approves Opsumit for Pulmonary Arterial Hypertension
Opsumit (macitentan) relaxes the pulmonary arteries, decreasing blood pressure in the vessels
Wednesday, October 23, 2013

CDC: U.S. Flu Activity Remains Low Through Mid-October
Percent of positive influenza specimens is higher in the Southeast versus rest of the country
Wednesday, October 23, 2013

ADHD Linked to Defecation Disorders in Children
Children with ADHD significantly more likely to have visits for constipation, fecal incontinence
Wednesday, October 23, 2013

BP Drugs Linked to Lower Risk of Alzheimer's Disease Dementia
For older adults with mild cognitive impairment, only diuretics linked to lower risk
Wednesday, October 23, 2013

Flu Vaccine Linked to Lower Cardiovascular Risk
Effect more pronounced in those with more active coronary disease
Tuesday, October 22, 2013

Intranasal Oxytocin Application Enhances Placebo Effect
Oxytocin may enhance placebo through effect of trust, empathy of administering physician
Tuesday, October 22, 2013

Study Probes Why Truckers Use Booze, Illicit Drugs
Use of psychoactive substances associated with poor working conditions
Tuesday, October 22, 2013

Pill Effects on Breast, Ovarian CA Same in High-Risk Women
Risk the same as found in women in the general population
Tuesday, October 22, 2013

Research Backlog at NIH Due to Shutdown
Labs suffered loss of momentum with their research; grant applications pushed back to November
Tuesday, October 22, 2013

Obama: 'No Excuse' for Troubled HealthCare.gov Website
But he insists that the health-reform law that created the site is good for the country
Monday, October 21, 2013

Seniors Rarely Consider Switching Medicare Plan, Provider
Despite reporting high satisfaction 59 percent cut spending for unexpected health care costs
Monday, October 21, 2013

Phentermine, Topiramate Reduce Progression to T2DM
Significant weight loss with extended-release tx for those with prediabetes/metabolic syndrome
Monday, October 21, 2013

Small Businesses Weigh Health Insurance Options
Most features of exchanges rated favorably, but prices for premiums are critical issue
Monday, October 21, 2013

Psychotropic Drugs Commonly Prescribed to Children With ASD
Polypharmacy also common in autism spectrum disorders
Monday, October 21, 2013

Timing of First Dose of Measles Vaccine Questioned
Greater risk of measles when first dose given earlier
Monday, October 21, 2013

ACEP: Characteristics of Patients With Opioid Overdose
Second study identifies factors associated with doctor-shopping
Friday, October 18, 2013

In Buying Exchange Insurance, It Helps to Have Help
New online marketplaces don't do enough to let consumers weigh their options, experts say
Friday, October 18, 2013

Sebelius: Exchange Launch 'Rockier Than We Would Have Liked'
HHS secretary said improvements under way at HealthCare.gov website
Thursday, October 17, 2013

'Coverage Gap' Likely to Affect 5.2 Million Uninsured Adults
Nationally, about 27 percent of uninsured adults in states without Medicaid expansion will be affected
Thursday, October 17, 2013

Adverse Drug Events More Likely to Present on Hospital Admission
In 2011, adverse events common for antibiotics and anti-infectives
Thursday, October 17, 2013

Steps Given to Minimize Burden of Prior Authorizations
Use payer's website, not phone; designated staff within practice should handle authorizations
Thursday, October 17, 2013

No Increase in Risky Sex After HIV Prophylaxis
Also no increase seen in sexually transmitted diseases or pregnancy
Thursday, October 17, 2013

Case Vignette: Calcium Supplements in Fracture Prevention
Case vignette article notes calcium-rich diet is preferred approach to ensuring adequate intake
Wednesday, October 16, 2013

Medicare, Medicaid Will Be Affected by Federal Debt Default
Failure to raise debt ceiling by Oct. 17 will impact nation's health care programs
Wednesday, October 16, 2013

Nonprofit U.S. Hospital CEO Compensation Varies Widely
Compensation tied to hospital technology deployment and patient satisfaction
Tuesday, October 15, 2013

No Link Between Nausea Drug and Birth Defects
Metoclopramide also not associated with an increased risk of abortion or stillbirth
Tuesday, October 15, 2013

More Steroid Courses No Better in Preterm Birth Strategy
No difference in death or disability at age 5 after single, multiple courses of antenatal corticosteroids
Tuesday, October 15, 2013

Sexual Minorities at Higher Risk of Teen Pregnancy
Lower hormonal contraception use and higher teen pregnancy rate for all except lesbians
Tuesday, October 15, 2013

Alternative Medicine Often Used by Youth With Headache
Complementary, alternative medicine more often used by those with multiple chronic conditions
Monday, October 14, 2013

Hospital Care Quality Varies by Insurance Coverage
Medicare patients appear most vulnerable to receiving inferior care
Monday, October 14, 2013

Review: Vitamin D Supplements Have Minimal Effect on BMD
Meta-analysis shows minimal effect on bone mineral density, with small benefit at femoral neck
Monday, October 14, 2013

Study Discusses How to Create Value in Insurance Marketplaces
Accrediting bodies play role in performance measures, setting standards, providing feedback
Monday, October 14, 2013

Smoking Cessation Meds Don't Increase Suicidal Behavior
Risk of self-harm, depression not up with varenicline, bupropion versus nicotine replacement tx
Monday, October 14, 2013

Higher Magnesium Intake May Lower Diabetes Risk
May be particularly beneficial in offsetting risk of developing diabetes among those at high risk
Friday, October 11, 2013

Regional Variation Seen in Medicare ACO Formation
Measures of underlying provider integration may drive accountable care organization formation
Friday, October 11, 2013

'Cyberchondria' Worse in Those Troubled by Uncertainty
For those with fear of uncertainty, greater Internet searching leads to greater health anxiety
Friday, October 11, 2013

Consumers Frustrated With First Days of ACA Exchanges
Three-quarters of those who tried to sign up for insurance reported problems
Friday, October 11, 2013

Levothyroxine May Be Overused for Borderline Thyroid Issues
Lowered threshold for levothyroxine initiation may result in less benefit, potential harm
Thursday, October 10, 2013

State-Run Health Exchanges Off to Smoother Start
Experts say that local insurance marketplaces are smaller so problems can be fixed faster
Thursday, October 10, 2013

ESICM: In Septic Shock, Esmolol Tied to Reduced Heart Rate
Esmolol linked to reduction in heart rates to target levels compared with standard care
Wednesday, October 09, 2013

ESICM: Statin Therapy Doesn't Cut Day-28 Mortality in VAP
No decrease in day-28 mortality for all patients, statin-naive with ventilator-associated pneumonia
Wednesday, October 09, 2013

AAFP Urges Congress to End Federal Government Shutdown
Shutdown is putting health of public at risk, with no impact on ACA funding
Wednesday, October 09, 2013

Greater Potential for Health Gains From Delayed Aging
Yet most medical research remains focused on fighting individual diseases
Wednesday, October 09, 2013

Patterns of Health Insurance Coverage Vary by State
States can tailor outreach efforts for coverage expansion to match the needs of their uninsured
Tuesday, October 08, 2013

Patient Satisfaction Is Poor Measure of Hospital Quality
And busier hospitals tend to perform better
Tuesday, October 08, 2013

Confusion Still Surrounds ACA Health Insurance Exchanges
However, Gallup poll suggests most will get insurance by December rather than pay a fine
Tuesday, October 08, 2013

Design and Software Problems Plague Health Exchanges
Efforts to improve the federal registration website are under way, officials say
Monday, October 07, 2013

Senators Request Delay in Transition to Meaningful Use 2
Noting that many providers and EHR vendors are not ready, senators ask for one-year delay
Monday, October 07, 2013

ACS: Surveillance Bias Noted in VTE Measurement
Hospitals with higher quality scores have higher VTE prophylaxis rates; worse risk-adjusted VTE rates
Monday, October 07, 2013

U.S. Health Exchange Website Faced Intermittent Shutdowns
HealthCare.gov offline after 1 a.m. ET a few hours each night this past weekend
Monday, October 07, 2013

Two-Dose Vaccination Program Cuts Varicella Incidence
Varicella incidence, hospitalizations, outbreaks all have declined since program initiation
Monday, October 07, 2013

Patient Portal Market Earned $279.8 Million in 2012
In the next five years, market is expected to reach $898.4, mainly driven by stage 2 meaningful use
Friday, October 04, 2013

Flu Vaccine Recommendations Updated for Egg-Allergic
Patients should have vaccine in primary care or allergist office, depending on allergy severity
Friday, October 04, 2013

IDSA: Antibiotics Still Overused in Bronchitis, Sore Throats
Two studies show antibiotic prescribed for most cases of acute bronchitis, sore throats in U.S. adults
Thursday, October 03, 2013

Impact of Shutdown on Docs, Patients Discussed
Meaningful use incentives unlikely to be affected; Medicare reimbursements will continue in short term
Thursday, October 03, 2013

Glitches Still Dog Online Health Exchanges
Officials work to correct problems, speed up capacity
Thursday, October 03, 2013

High Statin Dose Reduces Gum Inflammation
Study suggests further ties between inflammation in arteries and gums
Thursday, October 03, 2013

Fallout From Increase in High-Deductible Plans Examined
Increase likely with ACA implementation; research will aid creation of more sophisticated system
Thursday, October 03, 2013

Demand for Doctors Remained High in 2012
Physician recruiters from 156 organizations conducted nearly 5,000 active searches in 2012
Thursday, October 03, 2013

Expanding Scope of Nurse Practitioners Practice Discussed
Non-physician practitioners can ease burden on physicians; valuable in team-based care model
Thursday, October 03, 2013

Government Shutdown Impacting Health Care Agencies
Activities that relate to safety of human life and protection of property will not be affected
Thursday, October 03, 2013

Technical Problems Still Vex Day 2 of ACA Exchange Rollout
Federal officials remind consumers that enrollment runs through March 31, 2014
Wednesday, October 02, 2013

Exercise May Be As Effective As Drugs for Some Conditions
But diuretics more effective than exercise for lowering mortality in heart failure
Wednesday, October 02, 2013

USPSTF: Evidence Lacking for Tools to Lower Teen Drug Use
For adolescents, evidence lacking for primary care-based interventions to prevent, cut drug use
Wednesday, October 02, 2013

Technological Advances in Health Care for Google, Apple
Google launches company that will research health and wellness, with Apple chairman as CEO
Wednesday, October 02, 2013

Early IV Metoprolol May Reduce Infarct Size in MI Patients
β-blocker administered prior to primary percutaneous coronary intervention
Wednesday, October 02, 2013

Technical Glitches Mar Affordable Care Act Exchange Debut
Consumers are reminded that insurance enrollment runs through March 31, 2014
Wednesday, October 02, 2013

Opioid Use Often Continues After Bariatric Surgery
For chronic opioid users, dose often increases after surgery
Tuesday, October 01, 2013

FDA Approves Brintellix for Major Depressive Disorder
Clinical trials show drug is effective in treating depression and preventing future episodes
Tuesday, October 01, 2013

Hormone Therapy Not Useful for Chronic Disease Prevention
Extended follow-up of two trials indicates it may be useful for symptom management
Tuesday, October 01, 2013

Poor Performance Triggering EMR Switch for Small Practices
Small physicians practices leaving vendors as software systems fail to meet expectations
Tuesday, October 01, 2013

Many Health Care Professionals Oppose ACA Proposals
Despite recognizing benefits, 56 percent oppose most, if not all, proposals in law
Tuesday, October 01, 2013

Affordable Care Act Exchanges Are Up and Running
'Obamacare' marketplaces open amid some technical problems and a government shutdown
Tuesday, October 01, 2013

Lower National Health Spending Due to Slow Economy
Over the period of 2012 to 2022, national health spending expected to grow at 5.8 percent annually
Monday, September 30, 2013

Only One-Third of Voters Think Congress Should Delay ACA
About half of voters will blame the Republicans 'a lot' if the government shuts down
Monday, September 30, 2013

Medicare, Medicaid Will Still Run If Government Shuts Down
But other programs could be curtailed, according to contingency plans
Monday, September 30, 2013

EASD: First-Line Sulfonylureas Associated With Higher Mortality
Higher mortality in diabetes with sulfonylureas monotherapy compared with metformin
Monday, September 30, 2013

DOL Clarifies Employer Health Insurance Notification Duty
Companies should provide notification to employees by Oct. 1, but no fines for failing to do so
Monday, September 30, 2013

Non-Medical Exemptions One Factor in Pertussis Resurgence
Spatial clustering of NMEs seen in California in 2010; linked with clusters of pertussis cases
Monday, September 30, 2013

Trends in Psychotropic Med Use in Young Children Explored
Likelihood of use peaked in 2002 to 2005; more likely for boys, those lacking private insurance
Monday, September 30, 2013

Vitamin D Alone Doesn't Better Postmenopausal Bone Health
However, vitamin D in combination with calcium, or calcium alone, reduces bone turnover markers
Monday, September 30, 2013

HEALTH REFORM: ACA Impact on Medicare Recipients Unclear
Seniors may not grasp effects of health care reform
Friday, September 27, 2013

Practical Tips Offered for Medical Employee Satisfaction
Training, respect, and reward go a long way
Friday, September 27, 2013

Effect of Testosterone on CV Disease in Men Uncertain
Review of the literature conducted to assess low testosterone link to cardiovascular disease/mortality
Friday, September 27, 2013

Combo Approach Ups Flu Vaccine Receipt Among Pregnant Women
Providers must both recommend and offer the vaccine
Thursday, September 26, 2013

CDC: Flu Shot Coverage of Health Care Personnel Increasing
CDC finds that easy access to vaccination appears to be a motivator
Thursday, September 26, 2013

HEALTH REFORM: Medicaid Expansion Will Up Coverage
Many will benefit, but some will still fall through the cracks
Thursday, September 26, 2013

No Cognitive Protective Role Seen for Omega-3 Fatty Acids
No effect on age-associated cognition or rate of cognitive decline in older dementia-free women
Thursday, September 26, 2013

Antibiotic Protocol Selects Against Drug Resistance
Treatment cycles between compatible antibiotics
Thursday, September 26, 2013

More Options, Lower Premiums With Insurance Exchanges
HHS report finds health insurance premiums will be even less than expected
Wednesday, September 25, 2013

HEALTH REFORM: Exchanges Offer Options for the Uninsured
Tax credits will benefit low and moderate earners
Wednesday, September 25, 2013

ACP Provides Overview of Health Insurance Marketplaces
Ahead of enrollment, overview discusses implications for patients and physicians
Wednesday, September 25, 2013

HEALTH REFORM: Health Care Reform a Mixed Bag for Workers
Those with job-based coverage can expect some changes
Tuesday, September 24, 2013

FDA Gives Final Guidance on Mobile Medical App Oversight
Oversight will be focused on medical apps that could potentially pose greater risk to patients
Tuesday, September 24, 2013

USPSTF: Offer Breast CA Risk-Reducing Rx to High-Risk Patients
Tamoxifen, raloxifene recommended for women with raised risk, low risk of adverse meds effects
Monday, September 23, 2013

FDA Issues Final Rule for Device Identification System
The unique device identification system will improve patient safety, catalogue every device
Monday, September 23, 2013

HEALTH REFORM: Young People Likely to Be Key to Success
However, only about one-quarter of young adults are aware of health insurance exchanges
Monday, September 23, 2013

HFES: Multi-Tasking Can Impair Diagnostic Performance
Performing concurrent complex memorization task has negative impact of diagnostic performance
Monday, September 23, 2013

Use of Digoxin Ups Risk of Death in Systolic Heart Failure
No difference observed in risk of hospitalization for heart failure
Monday, September 23, 2013

HEALTH REFORM: Health Care Exchanges Going Into Effect
Coverage could start as early as January 2014
Monday, September 23, 2013

Metformin May Increase Risk of Cognitive Impairment
Calcium supplementation may ameliorate this risk
Friday, September 20, 2013

Monitoring Ups Adherence to Antiretroviral Prophylaxis
Active monitoring and counseling helps protect partner from HIV in serodiscordant couples
Friday, September 20, 2013

Statin Use Tied to Increased Risk of Cataracts
Relationship remains significant even when adjusting for other confounding variables
Friday, September 20, 2013

Rosacea Risk Higher in Female Migraine Sufferers
Risk of rosacea increases with age of migraineurs only in women
Friday, September 20, 2013

Lawyers File Most Isotretinoin Adverse Drug Reports
Findings based on inflammatory bowel disease reports tied to isotretinoin filed with the FDA
Friday, September 20, 2013

Millions Are Harmed by Unsafe Medical Care Each Year
About two-thirds of adverse events occur in low-income and middle-income countries
Thursday, September 19, 2013

EHR Systems Meeting Meaningful Use Criteria Beneficial
Most systems meet criteria; linked to time savings, reports of enhanced confidentiality
Wednesday, September 18, 2013

Enhanced Care Program Set Up at Six Mayo Clinic Hospitals
Program supplements usual care with computerized system that monitors patient's condition
Wednesday, September 18, 2013

CDC Report Sheds Light on Antibiotic-Resistant Infections
Misuse of antibiotics leading contributor to problem
Monday, September 16, 2013

Kids With Neuro Disorders No More Likely to Get Flu Vaccine
Despite high risk for complications, only about half of children with neuro disorders are vaccinated
Monday, September 16, 2013

High Burden of Endocarditis in Older Adults
But guidelines restricting antibiotic prophylaxis have not raised endocarditis mortality
Friday, September 13, 2013

Community-Level Intervention Cuts Antibiotic Prescribing
But does not influence knowledge and attitudes about correct antibiotic use
Friday, September 13, 2013

Nearly a Third of Vaccines at Pharmacies Given Off-Hours
Working-age, healthy, males are particularly likely to receive vaccines during off-clinic hours
Friday, September 13, 2013

Most Children in U.S. Receiving Recommended Vaccinations
Sustained coverage needed to keep disease burden low
Thursday, September 12, 2013

About Half of Health Care Providers Are 'Digital Omnivores'
Use tablet, smartphone, and laptop/desktop; prefer mobile devices for all tasks
Tuesday, September 10, 2013

Non-Medical Use of Prescription Drugs Drops in Young Adults
SAMHSA issues its annual report on substance use in the United States
Monday, September 09, 2013

'Meaningful Use' Achievement Not Uniform Across Hospitals
Critical-access, smaller, publicly-owned or nonprofit hospitals most at risk for 2015 penalties
Monday, September 09, 2013

Study of Topical Corticosteroid Use in Pregnancy Reassuring
No adverse outcomes studied linked except low birth weight with high potency exposure
Friday, September 06, 2013

Drug Non-Adherence Linked to Greater Pediatric Health Care Use
More hospitalizations, visits to the emergency department in children with chronic conditions
Thursday, September 05, 2013

Steroids Effective Short Term for Carpal Tunnel Syndrome
But most patients still have surgery after one year
Thursday, September 05, 2013

Continuation Phase Cognitive Therapy Beneficial in Depression
Second study shows lasting benefits of cognitive behavioral prevention program for at-risk teens
Thursday, September 05, 2013

AAP Updates Recommendations for Flu Prevention in Children
Annual universal immunization indicated with either trivalent or quadrivalent vaccine
Wednesday, September 04, 2013

Medication Adherence Up With Fixed Dose Combo Strategy
Improved adherence, reductions in systolic BP, LDL-C for patients with or at high risk of CVD
Wednesday, September 04, 2013

Immunization Schedules Don't Impact PCV13 Immunogenicity
For most serotypes, no significant difference for PCV vaccine administered in four schedules
Wednesday, September 04, 2013

Only Half of Hypertensive Adults Aware of Diagnosis
Only about a third of those treated achieve blood pressure control
Wednesday, September 04, 2013

ESC: Edoxaban Non-Inferior to Warfarin for VTE
Non-inferior with respect to recurrent symptomatic venous thromboembolism; superior for bleeding
Wednesday, September 04, 2013

Male-Female Physician Earnings Gap Has Persisted for 20 Years
No significant difference in the adjusted earnings of female physicians relative to males since 1987
Tuesday, September 03, 2013

Docs' Confidence in Diagnosis Unrelated to Diagnostic Accuracy
Vignette study shows little difference in confidence for cases diagnosed correctly, incorrectly
Tuesday, September 03, 2013

Hydroxyurea Cost-Effective for Childhood Sickle Cell Anemia
More effective, with lower medical costs, than placebo
Tuesday, September 03, 2013

Parental Goals Impact ADHD Treatment Preference
Medication for academic achievement, behavior therapy for behavioral compliance
Tuesday, September 03, 2013

Workaholics Have Poorer Physical and Mental Health
Working more than 50 hours per week linked to reduced physical and mental well-being
Monday, September 02, 2013

Employer-Based Health Insurance Premiums Rose Modestly in 2013
Smaller firms and those with many lower-wage workers asking beneficiary to pay more
Monday, September 02, 2013

Statins Appear to Benefit Elderly Without Previous CVD
Compared to placebo, statins reduce short-term MI and stroke risk, but do not improve survival
Friday, August 30, 2013

Comprehensive Stroke System Key to Reducing Death
American Heart Association and American Stroke Association release new recommendations
Friday, August 30, 2013

Discontinuing Aspirin Seven Days Before Spinal Surgery OK
Surgical outcomes similar for non-users, those who discontinue use at least seven days before surgery
Friday, August 30, 2013

CDC: Most Teen Immunizations on the Rise
But room for improvement still exists
Thursday, August 29, 2013

Prevalence of Rx Sleeping Aid Use 4 Percent for U.S. Adults
Prevalence increased for women versus men and with age, education; varies with sleep duration
Thursday, August 29, 2013

Oral Fluconazole in Pregnancy Not Linked to Most Birth Defects
Usual low doses appear safe, but may confer increased risk of tetralogy of Fallot
Wednesday, August 28, 2013

Final Rules Issued for Individual Shared Responsibility Mandate
Individual mandate starting in 2014; individuals expected to carry health insurance or get fined
Wednesday, August 28, 2013

Health Care Savings With Early Accountable Care Organizations
Reduced spending for elderly Medicare beneficiaries, but not necessarily improved quality
Wednesday, August 28, 2013

Use of Antipsychotic Meds Down in Nursing Homes
At least eleven states have already met or exceeded goal of 15 percent reduction in use
Wednesday, August 28, 2013

Severe Gastroenteritis Down in Older Children and Adults
Implementation of infant rotavirus vaccination in the U.S. in 2006 has reduced the burden of disease
Wednesday, August 28, 2013

More Pediatric HIV Patients on Antiretroviral Therapy
Rates of viremia, immunosuppression higher for older pediatric HIV cases, blacks, Hispanics
Tuesday, August 27, 2013

Calcium + Vitamin D Does Not Reduce Joint Symptoms
Joint pain, swelling common in postmenopausal women with or without supplementation
Monday, August 26, 2013

Correct Dose of Anti-Clotting Rx in Elderly Continues to Elude
Lower prasugrel dose has similar outcomes to usual clopidogrel dose in elderly heart patients
Monday, August 26, 2013

Most Drugs Safe to Take While Breastfeeding
New guidelines discuss safety of various classes of medications
Monday, August 26, 2013

Heroin Incidence Up for Those Using Non-Medical Pain Relief
3.6 percent of non-medical pain reliever initiates progress to heroin use within five years
Monday, August 26, 2013

Hispanic Teens More Likely to Engage in Substance Abuse
More likely to have used marijuana, ecstasy, cocaine, and to have abused Rx meds
Wednesday, August 21, 2013

Implications, Solutions for U.S. Health Disparities Discussed
Considerable disparities linked to geographic location, demographics; many can be prevented
Tuesday, August 20, 2013

Lasting Benefits With Insulin Pump Therapy for Children
Sustained improvement in glycemic control; drop in severe hypoglycemia, diabetic ketoacidosis
Tuesday, August 20, 2013

Expansion of Pharmacists' Practice Will Benefit Patients
Ethical, legal, financial, professional implications for docs; communication key during transition
Monday, August 19, 2013

HHS Awards $67 Million to Marketplace Navigators
Navigators will need to complete initial and ongoing training, renew certification annually
Monday, August 19, 2013

FDA: Fluoroquinolones May Cause Irreversible Nerve Damage
Risk applies only to those taken by mouth or injection
Friday, August 16, 2013

Few Urologists Follow Peri-Op Thromboprophylaxis Guidelines
About half of the members who responded knew about the AUA Best Practice Statement
Friday, August 16, 2013

Childhood ADHD Linked to Atopic Diseases, Impetigo
Independently increased odds of asthma, impetigo, antihistamine drug prescriptions
Friday, August 16, 2013

IOM Describes Themes Relating to Patients' Role in Health Care
Sessions describe their roles in informed care decisions, knowledge generation, value improvement
Friday, August 16, 2013

Liraglutide Augments Weight Loss in Pre-Type 2 Diabetes
Significantly more weight loss; improved insulin resistance, SBP, glucose, triglycerides
Thursday, August 15, 2013

Involved Patients Have Better Health Care Experiences
Patient knowledge, skills, and confidence influences response from the provider
Thursday, August 15, 2013

Vitamin D Doesn't Improve Blood Pressure in Elderly
Supplementation of vitamin D also did not improve vascular health measures
Wednesday, August 14, 2013

New Initiative Announced for Patient-Doc Collaboration
Center for Patient Partnership in Healthcare will include patient organizations, docs, nurse, PA
Tuesday, August 13, 2013

U.S. Hospitals Up Exchange of Electronic Health Information
Exchange of clinical care summaries and medication lists remains limited
Monday, August 12, 2013

ASA: Working Moms Experience More Stresses Than Dads
For mothers, job-linked concerns spill over into free time; thinking about family matters tied to stress
Monday, August 12, 2013

Guidelines for Post-HIV Exposure Management Updated
Exposed personnel should be provided with close follow-up, including counseling, HIV testing
Monday, August 12, 2013

ER Visits Related to Use of CNS Stimulants Up From '05 to '11
Among 18- to 34-year-old adults, increase in visits related to CNS stimulants with, without alcohol
Monday, August 12, 2013

Wide Treatment Variances Seen With ADHD Drugs
Variation signals disparity in how clinicians are utilizing clinical practice guidelines, authors say
Friday, August 09, 2013

Probiotic Preparation Doesn't Cut Antibiotic-Linked Diarrhea
Multi-strain preparation of lactobacilli and bifidobacteria not effective in older inpatients
Thursday, August 08, 2013

Self-Measured Monitoring Improves Blood Pressure
Findings only in the short-term, compared to usual care; effects beyond 12 months uncertain
Wednesday, August 07, 2013

Cumulative Metformin Linked to Mortality Post-Prostate Cancer
Both all-cause, prostate cancer-specific mortality reduced in elderly men with diabetes
Wednesday, August 07, 2013

Review Looks at Antibiotic Rx in Ambulatory Settings
More than one-fourth of prescriptions are for conditions in which antibiotics are rarely indicated
Wednesday, August 07, 2013

AMA, AHA Call for Realignment of Meaningful Use Stage 2
Letter to HHS expresses concern about readiness for stage 2; urges flexibility in adoption
Wednesday, August 07, 2013

Drug-Resistant Bacteria Spread Regionally Through Hospitals
Vancomycin-resistant enterococci increase at one hospital increases prevalence in other hospitals
Tuesday, August 06, 2013

No Increased Cancer Risk With Glargine Versus Human Insulin
Consistent results seen for any cancer and for breast, prostate, colon cancers
Tuesday, August 06, 2013

FDA Approves Shipping of Fluarix Quadrivalent Vaccine
GlaxoSmithKline vaccine is first quadrivalent flu vaccine; 10 million doses expected to be provided
Tuesday, August 06, 2013

Long-Term Calcium-Channel Blockers Tied to Breast CA Risk
Long-term current use linked to risk of ductal, lobular breast cancer in postmenopausal women
Monday, August 05, 2013

Asthma During Pregnancy Linked to Disease in Offspring
Higher risk of infectious and respiratory diseases
Monday, August 05, 2013

Antioxidants Don't Up Fertility Outcomes for Subfertile Women
Findings based on review of antioxidants versus placebo, no treatment, or another antioxidant
Monday, August 05, 2013

Participation Increases in Online CME Activities
In 2012, 82 percent of accredited CME activities did not receive commercial support
Monday, August 05, 2013

MMR, DTaP, Varicella Vaccine Coverage Close to 95 Percent
Median total of exemption rates 1.8 percent for children entering kindergarten in 2012 to 2013
Monday, August 05, 2013

Age Affects Aspirin Response in Patients With Stable CAD
Findings among patients with stable coronary artery disease taking similar relative aspirin doses
Friday, August 02, 2013

FDA Warns of Serious Skin Reactions to Acetaminophen
Link identified between the over-the-counter drug and potentially fatal skin reactions
Friday, August 02, 2013

Dexamethasone Beats Placebo for Cancer-Related Fatigue
More effective for reducing cancer-related fatigue; improvements in QoL and physical distress
Thursday, August 01, 2013

ASID: Doctors May Be to Blame for Antimicrobial Resistance
Five experts discuss the roles of animals, airlines, doctors, drug companies, nursing homes
Thursday, August 01, 2013

No MI Rate Advantage for Aggressive T2DM Glucose Control
More aggressive strategies do not reduce rate of myocardial infarction or preserve renal function
Thursday, August 01, 2013

Mandated Mental Health Treatment Programs Save Money
State-funded outpatient programs cut hospitalizations, costs among severely mentally ill
Thursday, August 01, 2013

Alcohol Use Down, Drug Use Up Among Pregnant Women
From 2000 to 2010, percentage of pregnant women reporting drug abuse up from 51.1 to 63.8
Thursday, August 01, 2013

OK to Continue Aspirin Therapy Up to Pancreatic Surgery
In observational study, aspirin use not linked to higher rates of perioperative bleeding, transfusion
Wednesday, July 31, 2013

Severe Hypoglycemia Common in Type 2 Diabetes
Highest risk for those with near-normal or very poor glycemic control
Wednesday, July 31, 2013

Severe Hypoglycemia Ups Cardiovascular Risk in Diabetes
Meta-analysis of cohort studies shows severe hypoglycemia linked with cardiovascular disease
Wednesday, July 31, 2013

Health 'Mutual Accountability' Pilot Program Launching
MedEncentive's health outcomes/costs improvement program to be tested over three years in Oklahoma
Wednesday, July 31, 2013

Reversal of Medical Practices Common Over Past Decade
Over 40 percent of studies that tested current practice led to medical reversal
Tuesday, July 30, 2013

Back Pain Management Relying on Guideline Discordant Care
From 1999 to 2010, increase in narcotic use, advanced imaging, referrals to other physicians
Tuesday, July 30, 2013

High H. pylori Cure Rate for Nonbismuth Quadruple Tx
Hybrid, concurrent optimized strategies achieve ≥90 percent cure rate in high resistance settings
Monday, July 29, 2013

Centrally Acting ACE Inhibitors Slow Decline in Dementia
Rate of cognitive decline slowed, especially during first six months of treatment
Monday, July 29, 2013

No Change in HPV Vaccine Coverage for Teen Girls in 2012
Increase reported from 2007 to 2011, not from 2011 to 2012; evidence indicates HPV4 is safe
Monday, July 29, 2013

FDA Updates Oral Nizoral Label to Reflect Safety Concerns
Concerns include severe liver injuries and adrenal gland problems, harmful drug interactions
Monday, July 29, 2013

Automated EHRs Improve Immunization Reporting
Reductions seen in historical lag time associated with submitted vaccination data
Friday, July 26, 2013

Flow Restrictors Protect Children From Liquid Medicine
Preschool-aged children have difficulty accessing liquid medicine in bottles with flow restrictors
Friday, July 26, 2013

IOM Confirms Geographic Variation in Health Spending
Geographically-based value index unlikely to be beneficial; decision making occurs at individual level
Thursday, July 25, 2013

Continuing Statins Linked to Decreased Risk of Parkinson's
Lipophilic statin therapy tied to decreased incidence of PD, particularly in women, elderly
Wednesday, July 24, 2013

HPV Vaccine Effective Against Oral Infections
Vaccine may play role in the primary prevention of HPV-associated oropharyngeal cancer
Wednesday, July 24, 2013

U.S. Physicians Not Supportive of Changes in Payment Models
Although docs agree on need to reduce costs, most don't want to eliminate fee-for-service approach
Tuesday, July 23, 2013

Deaths Estimated From Estrogen Avoidance After Hysterectomy
Thousands of deaths estimated in 50- to 59-year-old hysterectomized women, avoiding estrogen
Tuesday, July 23, 2013

Maternal Health Behaviors Affect Teen Boys' HPV4 Uptake
Findings underscore importance of targeting maternal health behaviors to prevent HPV
Tuesday, July 23, 2013

Clinical Trial Results for Cancer Drugs Often Not Published
Results for almost half of U.S. cancer drug trials not available three years after study completion
Tuesday, July 23, 2013

Pros and Cons of Electronic Cigarette Regulation Discussed
Two editorials discuss implications of regulations of ECs as medicinal devices in U.S., Europe
Tuesday, July 23, 2013

Tablets Help Physicians Keep Up With Medical Research
Smartphones mainly used to access drug information, to access research, communicate
Monday, July 22, 2013

Premiums Expected to Be About 20 Percent Lower in 2014
Proposed premiums for 2014 lower than expected for individual market and small group market
Monday, July 22, 2013

ADHD Drug May Reduce Risk of Falling in Elderly
Methylphenidate improves gait control in healthy older adults
Monday, July 22, 2013

Newer Anticoagulants Linked to Gastrointestinal Bleeding
Risk highest for venous thrombosis or acute coronary syndrome
Friday, July 19, 2013

Top Challenges for Docs Include Financial Management
Challenges include shifting reimbursement models, insufficient time with patients, ACA effects
Friday, July 19, 2013

Missed Diagnoses, Med Errors Most Common Malpractice Claims
Missed diagnosis represents 26 to 63 percent of all primary care claims across included studies
Friday, July 19, 2013

~2 Percent of Opioid Rx Bought by 0.7 Percent of Patients
Small subgroup of patients obtain an average of 32 prescriptions from 10 different providers
Thursday, July 18, 2013

Antipsychotics Induce Insulin Resistance Without Weight Gain
Drugs also do not affect mechanisms regulating eating behavior
Thursday, July 18, 2013

Low-Dose Aspirin May Reduce Women's Colorectal Cancer Risk
However, taking alternate-day aspirin does increase GI bleeding, ulcers
Wednesday, July 17, 2013

Free Postpartum Contraception Optimizes Pregnancy Intervals
Offering postpartum contraception to low-income women avoids short pregnancy intervals
Wednesday, July 17, 2013

Financial Incentives Can Drive Health IT Adoption
Financial incentives increased e-prescribing use even among existing users
Wednesday, July 17, 2013

ISSTDR: Two New Treatment Options for Gonorrhea
Two combinations based on existing drugs show promise for gonorrhea treatment
Tuesday, July 16, 2013

CMS Medicare Physician Fee Schedule Could Benefit Docs
However, proposed implementation of sustainable growth rate formula threatens primary care
Tuesday, July 16, 2013

Acid Reflux Medications May Constrict Blood Vessels
This mechanism may explain an increased risk of cardiovascular events in people taking PPIs
Tuesday, July 16, 2013

In U.K., Experts Call for HPV Vaccination for Young Gay Men
Vaccination of men, up to age 26 years, who have sex with men advised to prevent anal cancer
Tuesday, July 16, 2013

EHRs May Slow Growth in Ambulatory Health Care Costs
Among projected savings are significant decreases in ambulatory radiology costs
Monday, July 15, 2013

Tool Helps Emergency Providers ID Drug-Seeking Behavior
Although, ER docs already demonstrate skill at spotting patients who are drug-seekers
Monday, July 15, 2013

AAIC: Metformin Treatment Linked to Lower Dementia Risk
Initiating treatment with sulfonylureas, thiazolidinediones, and insulin does not lower risk
Monday, July 15, 2013

CMS Proposes New Rule for Outpatient Payment Policies
Rule would expand categories of related items and services for outpatient prospective payment system
Monday, July 15, 2013

Novel Misoprostol Insert Reduces Labor Time, Need for Oxytocin
Compared to women receiving dinoprostone vaginal insert in phase III trial
Friday, July 12, 2013

Omega-3 Fatty Acids Linked to Risk of Prostate Cancer
High blood levels of long-chain omega-3 fatty acids tied to increased risk of prostate cancer
Friday, July 12, 2013

AMA Offers Guidance for Improving EHR Effectiveness
Policies established to help docs navigate patient communication while using electronic devices
Friday, July 12, 2013

Physicians Frustrated by Third-Party Interference
Frustrations vary for those employed in hospitals/institutions or in practice, partners
Friday, July 12, 2013

Grants of $150 Million for Community Health Centers
Walgreen Co. to distribute brochures to inform consumers about health law, obtaining coverage
Thursday, July 11, 2013

Health Searches May Be Leaked to Third Parties
Third-party tracking generally not present on government or physician-oriented sites
Thursday, July 11, 2013

U.S. Adults Value Health Care Provider Skill Evaluation
Most adults feel health care providers who treat them should adhere to a recertification program
Thursday, July 11, 2013

Docs Don't Often Talk to Patients About Dietary Supplements
Primary care docs discuss dietary supplements with patients in about one-quarter of visits
Thursday, July 11, 2013

Red Cross Issues Emergency Call for Blood Donors
Blood donations down about 10 percent in June; 50,000 fewer donations than expected
Thursday, July 11, 2013

One in Five U.S. Adults Will Have Trouble Paying Medical Bills
In 2013, 10 million adults with year-round health insurance expected to have bills they can't pay
Thursday, July 11, 2013

Tablets More Useful Than Smartphones for Docs Using EHRs
Fifty-one percent of tablet users access EHRs, compared with 7 percent of smartphone users
Wednesday, July 10, 2013

Health Insurance Marketplaces Not Required to Verify Claims
Due to legislative and operational barriers, they can rely on self-reported information
Wednesday, July 10, 2013

Improvement Needed in Drug Post-Marketing Studies
Many studies have not yet been started and studies with delays have doubled
Wednesday, July 10, 2013

Digital Divide Plagues Underserved Areas
Lower adoption of EHRs seen in underserved areas across the United States
Tuesday, July 09, 2013

Statins Usually Well Tolerated, With Few Adverse Effects
Simvastatin and pravastatin appear safer and more tolerable compared to other statins
Tuesday, July 09, 2013

Vitamin D, Coronary Heart Disease Link Varies by Race
Low concentrations of 25(OH)D linked to increased risk of CHD for whites, Chinese
Tuesday, July 09, 2013

Soy Supplement Doesn't Cut Prostate Cancer Recurrence
No reduction in biochemical recurrence within two years of radical prostatectomy
Tuesday, July 09, 2013

Supplement Use Common Among Facial Cosmetic Surgery Patients
Herbal supplement use significantly more common among females and older patients
Tuesday, July 09, 2013

Adoption of Electronic Health Records Is Progressing
In 2012, 44 percent of hospitals have an EHR; 42 percent implement stage 1 meaningful use
Tuesday, July 09, 2013

ASCO Urges Breast Cancer Chemoprevention Discussion
ASCO encourages providers to speak to women at increased risk about the benefits, hazards
Tuesday, July 09, 2013

Dose Reduction Ups Recovery After First-Episode Psychosis
Reduction or discontinuation of antipsychotics associated with better long-term recovery
Monday, July 08, 2013

Home Telemonitoring Intervention Ups BP Control
Greater proportion of patients with BP control during 12-month intervention, six-month follow-up
Wednesday, July 03, 2013

Drug Overdose Deaths, ER Visits Up for Women Since 1999
Five-fold increase in deaths, more than doubling of ER visits related to opioid pain relievers
Wednesday, July 03, 2013

Obama Administration: ACA's Employer Mandate Delayed
Major news out of the White House: the delay of the Affordable Care Act's employer mandate
Wednesday, July 03, 2013

Post-Breast Cancer, Metformin Has No Effect on Mortality
No effect seen on all-cause, cancer-specific death for women with breast cancer and diabetes
Tuesday, July 02, 2013

Hypertension, Lipid Control Improved, 1988 to 2010
Antihypertensive, antihyperlipidemic meds still needed in older, minority, diabetes, CVD patients
Tuesday, July 02, 2013

New Rule for Contraception Coverage, Religious Bodies
Rule respects religious concerns of non-profit organizations while allowing contraception access
Tuesday, July 02, 2013

Salsalate Improves Glycemic Control in Type 2 Diabetes
But drug also has some undesirable cardiac and renal effects
Tuesday, July 02, 2013

Prehospital Triage Policy for Suspected Stroke Ups tPA Use
Implementation of a prehospital stroke triage policy also ups use of emergency medical services
Monday, July 01, 2013

FDA Approves First Non-Hormonal Tx for Hot Flashes
Drug contains active ingredient found in antidepressant Paxil
Monday, July 01, 2013

ISTH: Apixaban Non-Inferior to Conventional Treatment for VTE
No significant difference in relative risk of recurrent VTE; less bleeding with apixaban
Monday, July 01, 2013

Etanercept Reduces Work, Activity Impairment in RA
Projected 12-month gain in work productivity partly or completely offsets costs of treatment
Monday, July 01, 2013

Avoidable Health Care Costs Exceed $200 Billion in 2012
Progress being made, with increases in meds adherence, use of generics, drop in antibiotics Rx
Friday, June 28, 2013

Bipartisan Recommendations Can Strengthen Health System
Recommendations related to Medicare, tax policy reform, preventive care, empowering states
Thursday, June 27, 2013

Study Examines Opiate Use in Orthopedic Trauma Patients
Patients more likely to use opiates before injury; pre-injury use predicts prolonged post-injury use
Thursday, June 27, 2013

Adults With Chronic Conditions Earn C+ for Meds Adherence
Twenty-four percent completely adherent; about half have two or more non-adherent behaviors
Wednesday, June 26, 2013

HHS Launches Insurance Marketplace Website, Call Center
Initiatives form part of consumer-focused education effort to help prepare for enrollment
Wednesday, June 26, 2013

8.5 Million Enrollees to Receive Health Insurance Rebates
Rebates averaging $100 per family to be paid as part of ACA '80/20' rule
Wednesday, June 26, 2013

Publicly Reported Mortality Predicts Hospital Performance
Hospitals with high performance on publicly reported index conditions have lower overall death rate
Tuesday, June 25, 2013

Guide Issued for Tying Primary Care to Regional Organizations
AHRQ guide will help assess readiness for linking EHRs to regional health information organizations
Monday, June 24, 2013

Survival of England's National Health Service Questioned
Financial austerity, administrative reorganization, report of shortcomings have caused turmoil in NHS
Monday, June 24, 2013

FDA Approves Plan B for All Females of Childbearing Age
No prescription is needed
Friday, June 21, 2013

CDC: Flu Vaccine Option Available for People With Egg Allergy
CDC advisory committee recommends FluBlok for people aged 18 to 49 with egg allergy or sensitivity
Friday, June 21, 2013

AHA: Intensive Statin Tx Doesn't Seem to Up Kidney Risk Post-ACS
Across two randomized trials, kidney injury incidence similar with intensive, less-potent statins
Friday, June 21, 2013

AHRQ Offers Strategies to Prevent Adverse Drug Events
Strategies provided for stages of ordering, transcribing, dispensing, administration of meds
Friday, June 21, 2013

Obesity Is a Disease, Says American Medical Association
New designation may intensify focus on prevention and treatment
Thursday, June 20, 2013

Practices Are Not Prepared for Implementation of ICD-10
Problems include lack of response from vendors, lags in internal software testing, external testing
Thursday, June 20, 2013

Potential of Mobile Remote-Presence Devices Discussed
Potential to increase access to and delivery of health care in developed, developing world
Wednesday, June 19, 2013

EHR Implementation First Step Toward Quality Improvement
Farzad Mostashari urges physicians to redesign care flow to maximize productivity of EHRs
Wednesday, June 19, 2013

New Rule Proposes Insurance Program Integrity Guidelines
Rule focuses on integrity of state Marketplaces; aims to safeguard federal funds, protect consumers
Wednesday, June 19, 2013

Penicillin Skin Testing Can ID Tolerance to β-Lactam Agents
Patients with reported history of penicillin allergy with negative PST tolerate β-lactam therapy
Wednesday, June 19, 2013

FDA Investigates Deaths of Patients on Antipsychotic Drug
Two patients died days after receiving Zyprexa injections
Wednesday, June 19, 2013

State-Based Health Care Price Websites Lacking
Greater focus needed on pricing for predictable, non-urgent services subject to deductibles
Tuesday, June 18, 2013

About 15 Percent of People Currently Uninsured in U.S.
In 2012, 6.6 percent of children, 26.4 percent of 19- to 25-year-olds uninsured at time of interview
Tuesday, June 18, 2013

Unauthorized Immigrants Make Up 1.4% U.S. Medical Spending
Infectious disease services, participation in insurance marketplaces may aid access to care
Tuesday, June 18, 2013

Some Antibiotics Up Risk of Statin Toxicity in Older Adults
Clarithromycin, erythromycin increase risk for statin toxicity; coprescription should be avoided
Monday, June 17, 2013

Initiating Statins Linked to Increased Risk of T2DM
Increased risk persists after adjustment; seen after initiation of simvastatin and atorvastatin
Monday, June 17, 2013

FDA Discusses Cybersecurity for Medical Devices, Hospitals
Medical device manufacturers and health care facilities should take appropriate preventive action
Monday, June 17, 2013

EULAR: RA Patients Discontinue Meds at Median of Two Years
Median time to discontinuation longer for those receiving tumor necrosis factor inhibitors
Monday, June 17, 2013

EULAR: Rate of RA Remission Down for Obese, Overweight
Overweight and obese patients have lower rate of remission at six and 12 months of follow-up
Monday, June 17, 2013

Duloxetine Moderately Cost-Effective for Treating Back Pain
Cost-effectiveness increases in populations over 65 years or with greater GI, cardiovascular risk
Friday, June 14, 2013

New Treatments Outperforming Placebo Becoming Less Common
Comparative effectiveness studies may be needed
Friday, June 14, 2013

School-Based Flu Vaccinations Cost-Effective
Future work needs to be done on improving delivery efficiencies to further reduce costs
Thursday, June 13, 2013

FDA: One Lot of Warfarin Being Recalled
Lot may contain oversized tablets
Thursday, June 13, 2013

Metformin Doesn't Reduce Gestational Diabetes With PCOS
Deterioration of insulin sensitivity is not affected by metformin treatment
Thursday, June 13, 2013

Survey Examines Physician Satisfaction With EHRs
About one-quarter of practices have no EHR; more than half of adopters report increased efficiency
Thursday, June 13, 2013

Use of EHRs Can Enhance Doc-Patient Communication
EHR use during clinical encounters can invite patients into participatory model of care
Wednesday, June 12, 2013

Education, Audit, Feedback Improve Antibiotic Rx
Findings based on pediatricians prescribing behaviors for bacterial respiratory infections
Tuesday, June 11, 2013

Medicare Beneficiaries Use More Brand-Name Drugs Than VA
Findings based on prescriptions filled by seniors with diabetes during 2008
Tuesday, June 11, 2013

Most Doctors Feel They Are Under-Using Mobile Apps
Most favor iPhones, tablets/iPads; most would use additional functionalities if they were available
Tuesday, June 11, 2013

Depression, Antidepressant Use Linked to Future CVD Risk
For participants with type 2 diabetes, correlation seen with development of CVD risk over four years
Monday, June 10, 2013

Methylphenidate, Nurses Calls Don't Improve Cancer Fatigue
Significant improvements in cancer-related symptoms with nursing telephone intervention
Friday, June 07, 2013

Higher Vitamin D Linked to Reduced Diabetes Risk
Analysis pools results from 21 studies
Friday, June 07, 2013

Large Randomized Trial Will Compare Diabetes Medications
GRADE, a pragmatic, unmasked clinical trial, will evaluate each of four meds added to metformin
Friday, June 07, 2013

FDA Panel Votes to Loosen Restrictions on Avandia
Expert panel reviews data on heart damage attributed to controversial drug
Friday, June 07, 2013

Lixisenatide Non-Inferior to Exenatide for Diabetes
Once-daily lixisenatide gives similar diabetes control as twice-daily exenatide
Thursday, June 06, 2013

Fish Oil Supplementation May Lower Risk of Diabetes
Meta-analysis shows fish oil supplements moderately increase circulating adiponectin
Thursday, June 06, 2013

HHS: Marketplaces Open New Insurance Options for Consumers
New health insurance choices will be available in most states via Health Insurance Marketplaces
Thursday, June 06, 2013

Statins May Lower Esophageal Cancer Risk
Findings include consistent benefit among high-risk patients with Barrett's esophagus
Thursday, June 06, 2013

One-Third of Women Willing to Delay Rx for Suspected UTI
In majority of women willing to delay antibiotics, symptoms spontaneously resolve within one week
Wednesday, June 05, 2013

Aspirin Post Hip Replacement OK for Extended Prophylaxis
Aspirin for 28 days non-inferior and as safe as dalteparin for preventing venous thromboembolism
Wednesday, June 05, 2013

Few Physicians Meeting Meaningful Use in Early 2012
Managing patient populations with electronic systems not easy for many physicians
Wednesday, June 05, 2013

Twitter Analysis Can Inform Vaccination Campaigns
Most medical information shared on Twitter is from substantiated, professional sources
Wednesday, June 05, 2013

CDC: Small Drop in Those With Difficulty Paying Medical Bills
Decrease in adults (<65 years) and children in families with difficulty paying medical bills
Tuesday, June 04, 2013

Increasing Drug Rx Linked to Exposure, Poisoning in Children
Strongest link seen for opioids; greatest risk across all medications seen for 0- to 5-year-olds
Monday, June 03, 2013

Religious Vaccine Exemptions Increasing in New York State
Second study supports immunization at sick visits rather than waiting for well-baby visits
Monday, June 03, 2013

Health of Nation Reviewed With Focus on Emergency Care
Twenty percent of people reported visiting emergency department at least once in last year
Monday, June 03, 2013

New Meds, Medical Devices Up Heart Failure Outcomes
Findings in patients with advanced heart failure referred to a tertiary university medical center
Friday, May 31, 2013

Standard VTE Prevention Supported for Bariatric Surgery
Review looks at both intravascular filters and augmented pharmacologic dosing strategies
Friday, May 31, 2013

With Legalization, Marijuana Poisoning Up in Youth
Findings based on children who sought care before, after Colorado legalized medical marijuana
Friday, May 31, 2013

New Statement Released by Anticoagulation Forum
Consensus statement to help organizations develop better systems to cut medication errors
Friday, May 31, 2013

No Effect of Attention Deficit Drugs on Substance Abuse
Childhood treatment with psychostimulants does not increase or decrease risk
Friday, May 31, 2013

Exserohilum rostratum Can Relapse After Antifungal Tx
80-year-old man relapses after antifungal therapy, resolution of symptoms and CSF white-cell count
Friday, May 31, 2013

Double-Dose Oseltamivir Not Beneficial in Severe Influenza
No virological or clinical advantage compared with standard-dose treatment for children, adults
Friday, May 31, 2013

Meta-Analysis Compares Vascular Risks for NSAIDs
Diclofenac and possibly ibuprofen linked to increased vascular risk; less risk for naproxen
Thursday, May 30, 2013

One-Third of Medical Students Have Implicit Anti-Fat Bias
Most are unaware of their significant implicit bias, although it could affect quality of care
Thursday, May 30, 2013

For Women, Calcium Intake Tied to Reduced Mortality Risk
Link not modified by vitamin D intake; no link observed with vitamin D or calcium intake in men
Thursday, May 30, 2013

Antiviral Resistance Identified in Novel Flu A/H7N9
In case series of 14 patients, two identified with Arg292 Lys mutation in virus neuraminidase gene
Thursday, May 30, 2013

Majority of Clinicians Support Medicinal Marijuana Use
Based on votes and responses to interactive feature, 76 percent support use of marijuana
Thursday, May 30, 2013

Billions Can Be Saved With Pharmacy Benefit Management
Strategies include use of generic drugs, affordable brands, negotiation of pharmacy dispensing fee
Wednesday, May 29, 2013

Vaccine for Enterovirus-71 Effective Against Disease
Ninety percent efficacy against hand, foot, mouth disease; 80.4 percent against EV71-linked disease
Wednesday, May 29, 2013

Transparency Key to Improving Value Care for Patients
Data on price, utilization, and quality should be made publicly available to ensure greater value
Wednesday, May 29, 2013

ASC: Rapid BP Lowering Tx No Better for Intracerebral Bleed
No significant reduction in death, severe disability with intensive versus guideline-recommended tx
Wednesday, May 29, 2013

AAN Releases Periprocedural Anticoagulant Care Guideline
Risk of bleeding from antithrombotic medications varies according to medical procedure
Tuesday, May 28, 2013

HHS: End-of-2013 Targets for EHR Use Already Reached
>50 percent of doctor offices, 80 percent of eligible hospitals using electronic health records
Tuesday, May 28, 2013

ACOG Endorses CDC Vaccine Recommendations in Pregnancy
Given newborn's vulnerability to pertussis, Tdap vaccine recommended during each pregnancy
Tuesday, May 28, 2013

FDA Approves A1c Test for Diabetes Diagnosis
Test is first of its kind to receive clearance for this purpose
Tuesday, May 28, 2013

ESC: Coenxyme Q10 Beneficial for Heart Failure
Patients receiving supplementation have reduced heart failure hospitalization, cardiovascular death
Tuesday, May 28, 2013

Not All Parents Think They Can Influence Teen Drug Use
More than 90 percent of parents of 12- to 17-year-olds report discussing substance use in past year
Tuesday, May 28, 2013

Docs Anticipating Changes Ahead As ACA Progresses
Most expect ACA to continue as planned; expect further integration for themselves, hospitals
Monday, May 27, 2013

Pain Conditions Linked to Increased Risk of Suicide
Back, migraine, and psychogenic pain increases risk of suicide in patients using VHA services
Monday, May 27, 2013

Depression Linked to Severe Hypoglycemia in Diabetes
Shorter time to first episode, higher number of severe episodes in depressed versus non-depressed
Friday, May 24, 2013

Glaucoma Drugs Linked to Eyelid Drooping
Prostaglandin analogues associated with problems that can interfere with vision
Friday, May 24, 2013

No Benefit of Intensive Insulin Rx in Hyperglycemia in Hospitalized
Guidelines from the American College of Physicians note that insulin may cause harm
Friday, May 24, 2013

Glucosamine Supplementation Linked to Intraocular Pressure
Reversible effect seen, with drop in intraocular pressure after discontinuation of supplementation
Friday, May 24, 2013

About One in Four Uninsured Could Be Excluded From ACA
Twenty-seven percent of those eligible for assistance tax credits do not have checking account
Friday, May 24, 2013

Data Support Basing Health Decisions on Both Benefit, Cost
Health care cost varies from $2 to $224 per month of health status-adjusted life expectancy
Friday, May 24, 2013

Frequent Heartburn Linked to Cancer of Pharynx and Larynx
Antacid use may lower risk
Thursday, May 23, 2013

Studies Discuss Complications of Type 2 Diabetes in Youth
Series of studies, editorials discuss complications, including retinopathy, cardiovascular disease
Thursday, May 23, 2013

ACOG: Hormone Therapy Not Recommended to Prevent CHD
For menopausal women, heart-healthy lifestyles and other strategies recommended to reduce risk
Thursday, May 23, 2013

Long-Acting Bronchodilators Up Cardiovascular Risk in COPD
Findings among older adults newly prescribed long-acting β-agonists or anticholinergics
Thursday, May 23, 2013

Parents Unaware of Scope of Teens' Use of 'Study Drugs'
One in 100 parents believe their teens use study drugs, while one in eight 12th graders report use
Thursday, May 23, 2013

Stimulant Normalizes Brain Activation in Youth With ADHD
Methylphenidate ups brain activation in children with attention-deficit/hyperactivity disorder
Wednesday, May 22, 2013

ATS: Azithromycin Delays Next Hospitalization in COPD
Significant prolongation of time to next respiratory hospitalization with antibiotics
Wednesday, May 22, 2013

Fecal Microbiota Tx Feasible for Recurrent C. difficile in HIV
Observation from two patients shows no further recurrence of C. difficile after fecal transplant
Wednesday, May 22, 2013

Systematic Screening of Med Adherence Will ID Barriers
Tailored interventions will be feasible following systematic monitoring of adherence
Wednesday, May 22, 2013

SSRI Reduces Stress-Induced Myocardial Ischemia
Escitalopram reduces mental stress-induced ischemia in at-risk patients
Tuesday, May 21, 2013

ATS: Short Steroid Course Non-Inferior for COPD Exacerbations
Five-day systemic glucocorticoid tx non-inferior to 14-day tx for reexacerbations within 180 days
Tuesday, May 21, 2013

Oxandrolone Not Effective for Pressure Ulcer Treatment
For veterans with spinal cord injury no benefit over placebo for healing or ulcers remaining closed
Tuesday, May 21, 2013

Study Examines Outbreak of Spinal Infections in Michigan
Increased case finding may partially explain more cases found in Michigan
Tuesday, May 21, 2013

USPSTF: Primary Care Docs Can Promote Dental Health
Grade B recommendation for use of oral fluoride supplementation, fluoride varnish for under-5s
Tuesday, May 21, 2013

DDW: Vitamin D May Be Beneficial in Crohn's Disease
Improvements in muscle strength, fatigue, quality of life for patients with stable Crohn's
Monday, May 20, 2013

Digital Divide Exists With Physician EHR Adoption
Adopters found to be optimistic about IT's potential, while non-adopters remain skeptical
Monday, May 20, 2013

Whole-Cell Pertussis Vaccines More Effective Protection
Teens who received DTaP have significantly higher risk of developing pertussis during outbreak
Monday, May 20, 2013

Marijuana Use Tied to Lower Fasting Insulin Level, HOMA-IR
Current users have lower fasting insulin, lower insulin resistance, smaller waist circumference
Friday, May 17, 2013

Prednisolone Disturbs Carbohydrate Metabolism
Patients with inflammatory diseases should consider other anti-inflammatory agents
Friday, May 17, 2013

ASH: Practicing Yoga May Help Lower Blood Pressure
Yoga two to three times a week on average lowers both systolic and diastolic BP by three points
Thursday, May 16, 2013

Meds for Back Pain Tied to Higher Erectile Dysfunction Risk
Dose and duration of opioid use associated with increased odds of erectile dysfunction
Wednesday, May 15, 2013

Primrose Oil, Borage Oil Not Effective Eczema Treatment
Findings based on extensive literature review over several decades of research
Wednesday, May 15, 2013

Combination Osteoporosis Rx Further Improves Bone Density
Teriparatide and denosumab administered together more effective than either therapy alone
Wednesday, May 15, 2013

Hospital Hypoglycemia Rates Up in Black Men With Diabetes
Home diabetes regimen partially explains the increased risk of hypoglycemia
Tuesday, May 14, 2013

Review: In-Hospital Antibiotic Rx Behavior Can Be Improved
Meta-analyses show that restrictive and persuasive methods improve prescribing in hospital setting
Tuesday, May 14, 2013

FDA Approves Breo Ellipta for Treatment of COPD
Respiratory disease is the third-leading cause of death in the United States
Monday, May 13, 2013

New FDA Survey to Assess Doc Attitudes on DTC Advertising
New survey will examine attitudes among non-physicians, including nurses, physician assistants
Monday, May 13, 2013

Specific Antibiograms Needed for Outpatients in Primary Care
Differences in susceptibility to ciprofloxacin among P. aeruginosa for inpatients, primary care
Friday, May 10, 2013

User Satisfaction With Electronic Health Records Down
Twelve percent decrease in user satisfaction since 2010; increase in very dissatisfied users
Friday, May 10, 2013

Poor Service, Bedside Manner Top Patients' Online Complaints
Review of 'rate-your-doctor' websites reveals patients' most common gripes
Friday, May 10, 2013

HRS: No Need to Stop Warfarin for Pacemaker, ICD Surgery
Fewer significant pocket-device hematomas for continued warfarin versus bridging heparin
Thursday, May 09, 2013

Antidepressants Benefit Post-CABG Mental Health Recovery
Escitalopram doesn't affect mortality, morbidity, but improves depression, mental health
Thursday, May 09, 2013

Smartphones, Smartphone Apps Increasingly Used by Docs
Two reports show use of smartphones and apps for professional purposes is increasing
Thursday, May 09, 2013

HHS Releases Data on Inpatient Charges for Hospital Services
HHS is also providing funding to data centers to collate, analyze, publish data to assist consumers
Thursday, May 09, 2013

n-3 Fatty Acids No Benefit for High-Risk Cardio Patients
No drop in cardiovascular mortality or morbidity for patients without myocardial infarction
Wednesday, May 08, 2013

ARVO: Additional Nutrients Do Not Reduce Progression to AMD
Adding carotenoids, omega-3s does not further lower risk of age-related macular degeneration
Wednesday, May 08, 2013

Application for Health Coverage Has Been Simplified, Shortened
First-time consumers will be able to complete one three-page application, see all available options
Wednesday, May 08, 2013

Guidelines Issued for Exercise-Induced Bronchoconstriction
Evidence-based guidelines developed for diagnosis and appropriate management of EIB
Wednesday, May 08, 2013

Ambrisentan Not Effective in Idiopathic Pulmonary Fibrosis
Increased risk of disease progression, respiratory hospitalizations with ambrisentan treatment
Tuesday, May 07, 2013

AUA: Many Men With Erectile Dysfunction Untreated
Under-treatment persists despite heavy promotion in the media
Monday, May 06, 2013

AUA: Low-Dose Pill Linked to Chronic Pelvic Pain Symptoms
Low-dose OCP users also have increased incidence of pain or discomfort during or after climax
Monday, May 06, 2013

PAS: Children With Strep Don't Need to Toss Toothbrushes
Toothbrushes from children with GAS did not show GAS bacterial growth
Monday, May 06, 2013

AAP Endorses Pediatric Acne Management Guidelines
Evidence-based treatment recommendations provide guidance for childhood, adolescent acne
Monday, May 06, 2013

Medicaid Coverage Doesn't Lead to Better Physical Health
After two years, no reductions noted in measured BP, cholesterol, or glycated hemoglobin levels
Thursday, May 02, 2013

Nearly One-Third Don't Pick Up New Osteoporosis Rx
Women receiving Rx from rheumatology, internist practicing 10 or more years more likely to get meds
Thursday, May 02, 2013

Health Industry Payment Details to Be Publicly Available
New CMS website will detail financial ties between drug, device manufacturers and docs, hospitals
Thursday, May 02, 2013

Penicillin Prophylaxis Prevents Recurrent Leg Cellulitis
Protective effect disappears after stopping treatment
Wednesday, May 01, 2013

Azithromycin Not Tied to Increased Risk of CV Death
Versus no antibiotics, penicillin; based on a general population of young, middle-aged adults
Wednesday, May 01, 2013

SAMHSA: Sharp Rise in ER Visits Due to Zolpidem
Emergency department visits up over 200 percent from 2005 to 2010
Wednesday, May 01, 2013

Plan B Approved for Women 15 Years and Older Without Rx
FDA says company submitted data showing that women 15 years and older understood proper use
Wednesday, May 01, 2013

Breath Test Can Detect Illicit Drug Use Up to 24 Hours Later
Simple, commercially available breath sampler can detect 12 analytes
Wednesday, May 01, 2013

FDA Approves Kcentra to Reverse Anticoagulation
Can be administered faster than plasma to stop severe bleeding in heart patients
Tuesday, April 30, 2013

Novel System Proposed for Accountable Cancer Care
Cancer Care Groups proposed, which would be compensated under bundled payment system
Tuesday, April 30, 2013

Comprehensive Analysis Supports SERMs for Cutting Breast Cancer
Meta-analysis shows reduced incidence of breast cancer, especially in first five years of follow-up
Tuesday, April 30, 2013

Renewed Efforts From AAFP to Repeal OTC Provision in ACA
Provision will increase costs to health care system; add to burden on physician offices
Tuesday, April 30, 2013

Non-Inferior Response With Two-Dose HPV Vaccine
Non-inferior antibody response one month after last dose for girls receiving two or three doses
Tuesday, April 30, 2013

Multicenter Study Links Peri-Op SSRI Use to Adverse Outcomes
Increased odds of in-hospital mortality, bleeding, 30-day readmission, after adjustment
Tuesday, April 30, 2013

FDA Concerned Caffeinated Foods Could Harm Children
Such products becoming abundant in U.S. markets
Tuesday, April 30, 2013

High Doses of Saw Palmetto Appear Safe Over 18 Months
No evidence of toxicity for patients given doses of up to 960 mg daily for up to 18 months
Monday, April 29, 2013

Rx for High-Risk Meds Varies Widely in Medicare Advantage
Women, whites, low-income patients, and those in the South more likely to receive high-risk meds
Monday, April 29, 2013

Med Errors Common Among Pediatric Cancer Outpatients
Rate of 3.6 medication errors with injury per 100 patients; errors more common with non-chemo meds
Monday, April 29, 2013

Zoledronic Acid Linked to Early Increase in Sclerostin Levels
For postmenopausal women, sclerostin up within two days; returns near to baseline after 360 days
Monday, April 29, 2013

FDA Announces New Network to Focus Exclusively on Patients
Interactive tool designed to educate patients and advocates about processes of drug development
Monday, April 29, 2013

FDA: Purveyors of Phony Botox Targeting U.S. Practices
Products advertised through fax; not FDA approved
Monday, April 29, 2013

Medical Interns Spending Less Time With Patients
More time being spent at a computer since work hours were limited in 2011
Friday, April 26, 2013

Report Updates Impact of Hypoglycemia in Diabetes
Reviews outcomes, strategies, and current gaps in knowledge
Friday, April 26, 2013

Saturday Marks Sixth Annual Rx Drug Take-Back Day
Collection sites will be available around the country
Friday, April 26, 2013

Review: All Approved Drugs Similarly Prevent Migraines
Off-label angiotensin-inhibiting drugs and beta-blockers have favorable benefit-to-harm ratios
Thursday, April 25, 2013

One 12-Ounce Sweet Drink a Day Ups Risk of T2DM 22 Percent
Association for sweet drinks persists, even after adjustment for energy intake, body mass index
Thursday, April 25, 2013

Prevalence, Costs of Heart Failure Estimated for 2030
More than eight million U.S. adults expected to have heart failure by 2030; $70 billion in costs
Thursday, April 25, 2013

Physicians Less Empathetic in Talking to Heavy Patients
Patient weight plays no role in quantity of physicians' biomedical communications
Thursday, April 25, 2013

Analgesics in Endurance Events Can Have Serious Adverse Effects
GI, kidney, and cardiovascular adverse events may increase with analgesic dose
Thursday, April 25, 2013

Diabetes Target Achievement Up From 1999 to 2010, More Needed
Only 14.3 percent meet targets for glycemic control, BP, LDL cholesterol, and tobacco use
Wednesday, April 24, 2013

Diagnostic Errors Are the Leading Type of Malpractice Claim
Diagnosis-related payments from 1986 to 2010 totaled $38.8 billion
Wednesday, April 24, 2013

Maternal Use of Valproate Ups Risk of Autism in Offspring
Significantly increased risk of autism spectrum disorder, childhood autism with prenatal exposure
Tuesday, April 23, 2013

Peri-Noncardiac Op Exposure to β-Blockers Improves Outcome
Exposure tied to lower mortality for patients with two or more Revised Cardiac Risk Index factors
Tuesday, April 23, 2013

>40 Percent of Parents Give Cough Meds to Young Children
Despite warning label that products should not be used for young children, many parents give meds
Tuesday, April 23, 2013

Severe Cutaneous Adverse Rxns Up in Allopurinol Initiators
SCARs are rare; usually occur within first 180 days of initiating treatment
Tuesday, April 23, 2013

Drop in Genital Warts in Young Women Since HPV Vaccination
Five years into vaccination program, proportion of young women ≤30 years with genital warts down
Tuesday, April 23, 2013

Breast Density Linked to Breast Cancer-Specific Survival
For women treated with tamoxifen, decrease in mammographic density tied to improved survival
Tuesday, April 23, 2013

Parental Permissiveness Linked to Rx Drug Abuse, Misuse
About one-quarter of teens report abuse, misuse of prescription meds; about half use pot, alcohol
Tuesday, April 23, 2013

TEDMED: Patients Can Become Leaders on the Health Team
Communities can raise their own leaders; may be key approach to change at community level
Monday, April 22, 2013

TEDMED: Get the Joy Back Into Health and Wellness
Surgeon General talks about importance of bringing joy back into movement and medicine
Monday, April 22, 2013

TEDMED: Is the Obesity Crisis a Disguise for a Deeper Problem?
Surgeon-researcher discusses hypothesis that we may be 'blaming the victims'
Monday, April 22, 2013

Pot Smoking Linked to Some Metabolic Changes
Increase in visceral adiposity and adipose tissue insulin resistance
Friday, April 19, 2013

Patient-Centered Decision Making Ups Health Outcomes
Health care outcomes improved for 71 percent of contextual factors that were addressed by PCDM
Friday, April 19, 2013

FDA Approves Updated Label for Reformulated OxyContin
Reformulated OxyContin has physical, chemical properties that should cut potential for abuse
Friday, April 19, 2013

Family-Centered Teaching Rounds Good for Patients, Students
Higher patient satisfaction with exam room presentations; many residents have concerns
Thursday, April 18, 2013

Relative Proportion of MRSA Increasing in S. aureus Isolates
Methicillin-sensitive S. aureus becoming more resistant to antibiotics
Thursday, April 18, 2013

Community Benefit Spending Varies for Tax-Exempt Hospitals
Most spent on charity care, patient services; less spent on community health improvement
Wednesday, April 17, 2013

Glutamine, Antioxidants No Benefit to Critically Ill Patients
Glutamine linked to increase in 28-day mortality among critically ill adults with multiorgan failure
Wednesday, April 17, 2013

Endocrine Therapy Often Incomplete after Breast Cancer
Study examines factors associated with initiation and persistence of treatment
Tuesday, April 16, 2013

Risk of New-Onset Diabetes Varies With Different Statins
Lowest risk for pravastatin 40 mg/day; higher risk for rosuvastatin 20mg/day versus placebo
Monday, April 15, 2013

Quality Improvement Methods Up Appropriate Antibiotic Rx
Study focuses on children aged 3 months or older with community-acquired pneumonia
Monday, April 15, 2013

FDA Warns Consumers of Dangers of the Stimulant DMAA
Attempt to halt marketing of dietary supplements with DMAA after reports of illness, death
Monday, April 15, 2013

Cardiac Function Unaffected by Prior Intensive Insulin Therapy
Prior glycemic exposure and not prior intensive insulin therapy impacts cardiac parameters
Friday, April 12, 2013

Drug-Facilitated Weight Loss Benefits Cardiometabolic Status
Weight loss, including phentermine/topiramate-induced, linked to reductions in lipids, blood pressure
Friday, April 12, 2013

Topical Treatment Effective for Toenail Fungal Infection
Mycologic cure rate significantly higher with 48 weeks of efinaconazole versus placebo
Friday, April 12, 2013

Topical Anesthetics Effective for Premature Ejaculation
Significant improvements seen for ejaculatory control, sexual satisfaction, and distress
Friday, April 12, 2013

Speech Details Practices to Improve U.S. Health Systems
Mayo Clinic CEO outlines key steps to create high-quality, low-cost care in America
Thursday, April 11, 2013

Fish Oil Has No Effect on Depression in Pregnancy
Does not prevent depression during pregnancy or post-partum for at-risk women
Thursday, April 11, 2013

Sales Representatives Provide Inadequate Safety Information
Physicians ready to prescribe with lack of data on harmful effects of promoted medicines
Thursday, April 11, 2013

Variation Seen in U.S. Antibiotic Prescription Rates
Higher rates of prescriptions for children, older patients, as well as those in the South
Wednesday, April 10, 2013

Patients Using Different Rx Strategies to Save Money
Cost-saving strategies differ by age, health insurance status, and poverty status
Tuesday, April 09, 2013

Diclegis Approved for Nausea/Vomiting in Pregnancy
Doxylamine succinate and pyridoxine hydrochloride approved to treat pregnant women experiencing nausea and vomiting
Tuesday, April 09, 2013

AAN Issues Guidelines for Tapeworm Ix on Rise in U.S.
Study finds albendazole plus dexamethasone, prednisolone most effective
Tuesday, April 09, 2013

NYC Health Department, ER Docs Clash Over Opioid Guidelines
Some believe the recommendations unfairly target N.Y.C. emergency physicians
Tuesday, April 09, 2013

Amiodarone Treatment Is Linked to Higher Cancer Risk
Medication for arrhythmias may pose peril, especially in males with increasing dose
Monday, April 08, 2013

Majority of Americans Now Favor Legalizing Marijuana
Support for legalization increases across all ages, including younger and older adults
Monday, April 08, 2013

Growth Hormone Ups Height in Pediatric Dialysis Patients
Bone formation rates are higher with growth hormone, regardless of bone histologic features
Friday, April 05, 2013

Federal Judge Rules FDA Must Lift Restrictions on Plan B
U.S. must make 'morning-after' pill available over-the-counter for all without prescription
Friday, April 05, 2013

Statins Show Protective Effect Against Acute Kidney Injury
Initiating use prior to coronary artery bypass grafting surgery may modestly reduce risks
Friday, April 05, 2013

Prevalence of Self-Reported Hypertension Rises in U.S.
Increase is small, but significant, and proportion of adults taking medication is up as well
Thursday, April 04, 2013

CMS Announces Final Rates for Medicare Drug, Health Plans
Program updates for 2014 designed to lower beneficiary costs, increase value
Thursday, April 04, 2013

Glucocorticoids Are Tied to Increased Risk of Clots
Higher rates of venous thromboembolism seen in both present and recent medication users
Thursday, April 04, 2013

Patients Taken Off Statins Can Be Re-Challenged With Success
Study finds halting therapy could lead to many preventable cardiovascular events
Tuesday, April 02, 2013

FDA Allows Change to Nicotine Replacement Therapy Labels
Changes will include removal of warning not to use tx if smoking, chewing tobacco, using snuff
Tuesday, April 02, 2013

New Drug Approved for Type 2 Diabetes
Invokana blocks reabsorption of glucose by the kidneys
Monday, April 01, 2013

Many Uninsured Vets Will Be Eligible for Medicaid Under ACA
But most of uninsured will have new coverage options only if their state expands Medicaid
Friday, March 29, 2013

Using Internet Search Logs Can Help Identify Drug Interactions
Tool may alert authorities to potential problems and aid in surveillance of adverse events
Thursday, March 28, 2013

Study: Primary Care Extension Program Should Be Funded
Authors say PCEP important to improving public health, translating research into practice
Thursday, March 28, 2013

Certified Primary Stroke Centers Use More Rt-PA
Findings in nationwide comparison of patients with ischemic stroke
Tuesday, March 26, 2013

FDA Approves Inhaler for Cystic Fibrosis Patients
Antibiotic device treats Pseudomonas aeruginosa lung infections
Monday, March 25, 2013

Telehealth in Addition to Usual Care Not Cost-Effective
For adults with long-term health conditions, no increase in quality adjusted life years
Friday, March 22, 2013

Impact of Budget Sequestration on Health Care Discussed
Cuts will not be equal: Medicaid protected; 2 percent cut for Medicare; 8.2 percent cut for NIH
Thursday, March 21, 2013

Effect of Immigration Status on Medicaid Eligibility Discussed
Seventeen percent of low-income, uninsured nonelderly are unauthorized or recently legal
Wednesday, March 20, 2013

Manual Osteopathic Treatment Improves Chronic Back Pain
Patients report pain relief, but not improvements in back functioning or work disability
Wednesday, March 20, 2013

Chlorthalidone No Better Than Hydrochlorothiazide for HTN
Increased risk of hypokalemia seen with chlorthalidone among older adults
Wednesday, March 20, 2013

Conflict-of-Interest Disclosures Common at 2011 AAOS Meeting
All featured symposia at the American Academy of Orthopaedic Surgeons disclosed conflicts
Tuesday, March 19, 2013

Aristolochic Acid Nephropathy, a Global Health Problem
Review of widely used Chinese herbs identifies need for regulation and further study
Tuesday, March 19, 2013

Pharmacist-Led Home BP Program Shows Success
Patients report reduced readings, better control, and improved care for hypertension
Monday, March 18, 2013

Black Children Less Likely to Be Prescribed Antibiotics
Also less likely to be diagnosed with conditions requiring antibiotics, even from the same doctor
Monday, March 18, 2013

Final Rule in Notice of Benefit, Payment Parameters Issued
Rule expands on existing standards for risk adjustment, reinsurance, risk corridors
Friday, March 15, 2013

Pharmaceutical Companies Are Reducing Promotional Spending
Much less spent to promote biologics compared with small molecule drugs, study finds
Friday, March 15, 2013

Cardio Risks Need Evaluation Before Prescribing Statins
Study examines doctors' approach in relationship to baseline heart disease risks
Friday, March 15, 2013

Health Insurance Exchanges Will Mainly Be Run by Feds
Federal government will establish exchanges for 26 states; state-run exchanges for 17 states, D.C.
Friday, March 15, 2013

Rules Must Evolve to Allow New Drugs for Early Alzheimer's
Use of single scale combining cognition, function could allow drugs to be approved for early disease
Thursday, March 14, 2013

Stimulated Reporting Accounts for High Dabigatran Bleeding
Analysis of FDA Mini-Sentinel database shows bleeding rates no higher than for warfarin
Thursday, March 14, 2013

Vitamin D3 Supplementation Lowers Systolic BP in Blacks
Oral regimen for three months found to be effective, but no result seen on diastolic readings
Thursday, March 14, 2013

FDA Reaffirms Azithromycin Tie to Heart Rhythm Abnormalities
Drug label has been updated to strengthen Warnings and Precautions section
Wednesday, March 13, 2013

AAN: Add-On Drug Improves Memory in Alzheimer's Disease
Researchers find positive effect from first human trials of a selective adrenoceptor antagonist
Wednesday, March 13, 2013

2009 H1N1 Vaccine Tied to Small Risk of Guillain-Barré Syndrome
Small but significant increase in risk with influenza (H1N1) 2009 monovalent inactivated vaccine
Wednesday, March 13, 2013

$120 Million to Be Sequestered From Health Centers in 2013
Losses likely to be more severe for health centers that are especially grant dependent
Tuesday, March 12, 2013

Worldwide, Contraceptive Prevalence Up Since 1990
Absolute number of women with demand for contraception likely to increase by 2015
Tuesday, March 12, 2013

ACC: High-Dose Vitamins Don't Cut Recurrent Cardiac Events
But high-dose vitamins plus active chelation may reduce events among patients with previous MI
Tuesday, March 12, 2013

ACC: Digoxin Cuts 30-Day Admission for Heart Failure
Drug shows no significant effect on mortality for seniors with reduced ejection fraction
Tuesday, March 12, 2013

Aspirin Cuts Melanoma Risk in Postmenopausal Caucasians
Dose-response association seen, with longer duration of use linked to greater reduction in risk
Monday, March 11, 2013

ACC: Cangrelor Reduces Ischemic Events in Primary PCI
And, prehospital fibrinolysis with timely angiography effective for reperfusion in STEMI
Monday, March 11, 2013

More Evidence of Waning Immunity of Pertussis Vaccine
Increasing risk of developing the illness in the six years after the last dose
Monday, March 11, 2013

FDA Encourages Opioid Prescribers to Pursue Training
Continuing medical education provided by opioid manufacturers set to combat misuse and abuse
Monday, March 11, 2013

ACC: Darbepoetin Alfa Doesn't Up Outcome in Heart Failure
For patients with mild-to-moderate anemia, treatment ups risk of thromboembolic events
Monday, March 11, 2013

Neonatal Size Unaffected by Gestational Diabetes Drugs
Changes in metabolic markers similar with metformin and insulin treatment
Friday, March 08, 2013

Opioid Guidelines for ER Docs Help, But More Study Needed
Efforts called important first steps toward addressing public health problem of abuse
Friday, March 08, 2013

Sleep Meds Up Hip Fracture Risk Among Nursing Home Residents
New users with mild cognitive impairment and those needing limited aid are most affected
Thursday, March 07, 2013

Cochrane Group Skeptical About Latest Roche Pledges
Roche has pledged to release full clinical study reports for Tamiflu, but conditions may apply
Thursday, March 07, 2013

Two Drug Classes Found Effective for Restless Legs Syndrome
Dopamine agonists, calcium channel alpha-2-delta ligands reduce symptoms
Wednesday, March 06, 2013

Clinical Trials Published Almost Two Years After Completion
Funding source, number of participants, and journal impact factor all affect time to publication
Wednesday, March 06, 2013

Nonheme Iron Intake Linked to Reduced Risk of PMS
Risk of premenstrual syndrome may be increased with high intake of potassium
Wednesday, March 06, 2013

Most Docs Report Information Overload in EHR-Setting
Docs who report information overload more likely to have missed results leading to delayed care
Wednesday, March 06, 2013

U.K. Health Performance Worse Than Comparable Countries
Tobacco, high blood pressure, high BMI leading risk factors for disability-adjusted life-years
Tuesday, March 05, 2013

Panel Recommends 10 Patient Safety Strategies
Ten strategies strongly encouraged for adoption; a further 12 strategies encouraged
Monday, March 04, 2013

CMS Reports on Progress Toward Improved Health Care
Progress includes slowing of growth in health care spending, decrease in readmissions
Monday, March 04, 2013

Computerized Provider Order Entry System Cuts Rx Errors
Given effect size, CPOE use, estimated reduction of 12.5 percent in medication errors each year
Monday, March 04, 2013

Sequestration to Impact Health Care-Related Programs
Medicare providers and medical researchers brace for cuts from fiscal impasse
Friday, March 01, 2013

Glucagonlike Peptide 1-Based Tx Increases Pancreatitis Risk
Findings among adults with type 2 diabetes taking exenatide, sitagliptin phosphate
Thursday, February 28, 2013

Isotretinoin Not Linked to Increased Risk of IBD
Case-control study and meta-analysis show no increased risk of ulcerative colitis, Crohn's
Wednesday, February 27, 2013

Ondansetron Not Linked to Adverse Fetal Outcomes
Findings in large cohort of women exposed to ondansetron during both early and mid-pregnancy
Wednesday, February 27, 2013

Risk of Child Narcolepsy Up With Pandemrix Vaccination
Increased odds of ASO3 adjuvanted pandemic A/H1N1 2009 vaccination before narcolepsy onset
Wednesday, February 27, 2013

AAAAI: EpiPens Should Be Given in Lower Thigh in Heavy Kids
In very obese children, calf injections offer greater chance of intramuscular administration
Wednesday, February 27, 2013

FDA Approves Osphena for Dyspareunia Post-Menopause
Once-daily pill carries boxed warning regarding risk of unusual endometrial bleeding, stroke, DVT
Wednesday, February 27, 2013

FDA: Omontys Injection Pulled From Market
Voluntary recall of anemia drug due to reports of anaphylaxis, including three deaths
Tuesday, February 26, 2013

Novel Chemotherapies More Often Used On- Than Off-Label
Off-label use, accounting for 30 percent, conforms to NCCN-supported indications in ~half of cases
Monday, February 25, 2013

USPSTF: Vitamin D, Calcium Supplements Don't Prevent Fx
For postmenopausal community-dwelling women, low-dose daily supplements not recommended
Monday, February 25, 2013

AAP Updates Guidelines for Acute Otitis Media
Updated guideline provides more stringent criteria to make a diagnosis and prescribe antibiotics
Monday, February 25, 2013

AAAAI: Omalizumab Treatment Effective for Urticaria
Reduces itch severity in patients resistant to antihistamines
Monday, February 25, 2013

CDC: 2012-2013 Flu Vaccine Not As Effective in Elderly
Vaccination appears to reduce need for office visits; preventive effect lower in elderly
Friday, February 22, 2013

Mental Health and Substance Use Disorder Benefits Expanded
New rule from HHS outlines standards for essential health benefits
Friday, February 22, 2013

CMS Proposes Payment and Policy Updates for 2014
Suggested changes will increase value and protection for beneficiaries
Thursday, February 21, 2013

FDA: Codeine After Surgery Puts Children At Risk
Food and Drug Administration urging use of alternative pain reliever
Thursday, February 21, 2013

IV Hydroxyethyl Starch Not OK in Critically Ill Patients
Compared to other resuscitation solutions there is an increased risk of death, kidney injury
Thursday, February 21, 2013

Extended Dabigatran Effective for Venous Thromboembolism
Carries lower risk of major, clinically relevant bleeding than warfarin; higher risk than placebo
Thursday, February 21, 2013

Pros, Cons of Medical Marijuana for Metastatic Cancer Explored
Case vignette highlights issues relating to smoking marijuana when conventional treatment has failed
Wednesday, February 20, 2013

Faster Adoption of Electronic Health Records Needed
Penalties under 2009 law start in 2015
Wednesday, February 20, 2013

Opioids Involved in Most Medical Overdose Deaths
Frequently involve drugs prescribed for mental health conditions
Wednesday, February 20, 2013

Erlotinib + Celecoxib Effective in Head and Neck Cancer
Combination therapy may help prevent head and neck cancer in high-risk patients
Wednesday, February 20, 2013

Multimodality Approach Needed to Reengineer Health Care
Rethinking, redesign, and application of necessary tools suggested for health care value reform
Tuesday, February 19, 2013

CMS: Unnecessary Medicare Regulations to Be Reformed
Proposed rule aims to increase ability of health care professionals to improve patient care
Tuesday, February 19, 2013

Artificial Intelligence Can Improve Patient Care
Modeling shows that computers can improve medical decisions and outcomes at lower costs
Tuesday, February 19, 2013

Depression Affects Efficacy of Herpes Zoster Vaccine
Elderly patients with depression have diminished response to vaccine, but antidepressants help
Tuesday, February 19, 2013

ASCO: Anticoagulant Use Predicts Metastatic Prostate CA Survival
Findings among men on any anticoagulant therapy while receiving docetaxel chemotherapy
Tuesday, February 19, 2013

Racial Disparities Observed in Opioid Monitoring
Black patients more often receive urine drug tests, less likely to receive pain specialist referral
Monday, February 18, 2013

CDC: Cephalosporin-Resistant Gonorrhea Imminent in U.S.
Asia, Europe report treatment failures; cefixime minimum inhibitory concentration up in U.S.
Monday, February 18, 2013

Therapy-Related Leukemia Risk Varied From 1975 to 2008
Risk after chemotherapy varies depending on initial cancer and treatment practices
Monday, February 18, 2013

SMFM: 17P Doesn't Prevent Preterm Labor in Twin Births
May actually be harmful in women with a short cervix carrying twins
Friday, February 15, 2013

Health Care-Associated Infections Decreased in 2011
Largest drop in central line-associated bloodstream infections; surgical site infections also down
Friday, February 15, 2013

Post-STEMI, Beta Blockers Cut Long-Term Mortality for Some
Higher- but not lower-risk patients benefit from beta-blocker therapy after PCI for STEMI
Friday, February 15, 2013

Use of Emergency Contraception Has More Than Doubled
~11 percent of women have ever used emergency contraception; up from 4.2 percent in 2002
Thursday, February 14, 2013

IOM Urges International Action to Eradicate Fake Drugs
Falsified and substandard meds are ineffective; may trigger resistance and cause illness, death
Thursday, February 14, 2013

Psychological, Sexual Impact of Female Breadwinners Explored
Men who are outearned by their wives more likely to use erectile dysfunction medications
Thursday, February 14, 2013

Selumetinib Ups Radioiodine Uptake in Thyroid Cancer
Increases radioiodine uptake and retention in patients with radioiodine-refractory disease
Wednesday, February 13, 2013

Oregon Experiment Will Provide Insight Into ACO-Based Reform
Program centered on coordinated care organization highlights challenges of contracting with ACOs
Wednesday, February 13, 2013

Diabetes Practice Patterns, Knowledge Gaps Identified
Findings presented for almost 1,000 health care providers who manage type 2 diabetes
Wednesday, February 13, 2013

Tedizolid Phosphate Viable for Bacterial Skin Infections
Tedizolid phosphate noninferior to linezolid in phase 3 trial, with good early clinical response
Wednesday, February 13, 2013

High Calcium Intake Linked to Increased Mortality in Women
Intake of >1,400 mg/day linked to increased all-cause, cardiovascular, but not stroke, mortality
Wednesday, February 13, 2013

Health Insurance Exchanges Are Top Priority on U.S. Agenda
Fifty-five percent view establishment of insurance exchange as top policy priority for their state
Wednesday, February 13, 2013

Potency of OTC Vitamin D Supplements Varies Widely
Over-the-counter pills from USP-verified manufacturers may have better accuracy
Tuesday, February 12, 2013

Maternal Folic Acid Use Linked to Reduced Autism Risk
Lower adjusted risk of autistic disorder but not other autism spectrum disorders
Tuesday, February 12, 2013

Study IDs Factors Associated With H. Pylori Eradication
Geographic site, demographics, adherence seem to be as important as antibiotic regimen
Tuesday, February 12, 2013

Naltrexone Linked to Reduction in Pain in Fibromyalgia
Low-dose treatment also improves mood and satisfaction with life
Tuesday, February 12, 2013

Use of Evidence-Based Meds Increasing for STEMI, NSTEMI
ACE inhibitor, antiplatelet and lipid-lowering therapies, beta-blockers, aspirin use increasing
Tuesday, February 12, 2013

Most Cardiac Patients Report Using Alternative Treatments
Almost half report interest in participating in research trials with CAM therapies
Monday, February 11, 2013

Brain Activity Linked to TNF Inhibitor Response in RA
Response to tumor necrosis factor inhibitors associated with activity in pain-related brain areas
Monday, February 11, 2013

Increasing Patient Activation Tied to Lower Health Care Costs
Having a higher score on the Patient Activation Measure linked to improved outcomes, lower costs
Monday, February 11, 2013

Statin Use Linked to Reduced Risk of Hepatocellular Cancer
Findings strongest in Asian populations, but also noted in Western populations
Monday, February 11, 2013

Long-Acting Daily Opioids Increase Risk of Hypogonadism
In men taking daily opioids, duration of action, but not dose, affects risk of hypogonadism
Friday, February 08, 2013

Most Dietary Supplement Use Not Recommended by Docs
Study looks at reasons motivating use of dietary supplements in adults
Friday, February 08, 2013

High Doses of Saw Palmetto Don't Impact Serum PSA
For men with lower urinary tract symptoms, saw palmetto has no effect on PSA versus placebo
Friday, February 08, 2013

ECT + SSRI Better for Major Depression Than Either Alone
Electrical current therapy plus sertraline more effective than either treatment alone
Thursday, February 07, 2013

Doctors' Perceptions of Psoriasis Therapies Vary
Beliefs on safety and efficacy vary; treatment preference not predictive of perceptions
Thursday, February 07, 2013

ASA: Pot Use May Be Linked to Increased Stroke Risk
Patients with ischemic stroke, transient ischemic attack more likely to have recently used cannabis
Wednesday, February 06, 2013

Rivaroxaban Found Noninferior to Enoxaparin in Acutely Ill
Extended-duration rivaroxaban has better efficacy than enoxaparin, but linked to increased bleeding
Wednesday, February 06, 2013

Corticorelin Acetate Has Steroid-Sparing Effect in Brain Cancer
In peritumoral cerebral edema, corticorelin acetate improves steroid-induced myopathy
Wednesday, February 06, 2013

Ramipril Improves Walking in Peripheral Artery Disease
Duration of pain-free and maximum walking increased; linked to improved physical function
Wednesday, February 06, 2013

Men's Risk of Kidney Stones Up With Ascorbic Acid Supplements
Dose-dependent effect seen with up to two-fold increased risk after multivariate adjustment
Wednesday, February 06, 2013

FDA Warns Consumers About Fraudulent Flu Products
Fraudulent products can be found online; include non-FDA-approved generic Tamiflu, Relenza
Tuesday, February 05, 2013

Antipsychotic Rx for 22 Percent of Nursing Home Residents
Based on prescribing patterns, off-label indications related to dementia likely
Tuesday, February 05, 2013

Exenatide Lowers BMI, Weight in Severely Obese Teens
Glucagon-like peptide-1 agonist linked to greater reduction in BMI, body weight versus placebo
Tuesday, February 05, 2013

Supplemental Calcium Tied to Higher CVD Death Risk in Men
Dietary calcium consumption not linked to cardiovascular disease death in men or women
Tuesday, February 05, 2013

Stopping Aspirin Therapy After GI Bleed Ups Cardiovascular Risk
Risk of death or acute CV event is seven-fold higher for those who discontinue aspirin therapy
Monday, February 04, 2013

Contraception Coverage Rules Issued for Public Comment
Proposed rules for contraception coverage with no cost sharing reflect feedback, religious concerns
Monday, February 04, 2013

CDC: Flu Activity Still Up in U.S. in Fourth Week of 2013
Pneumonia and flu-linked deaths above epidemic threshold; eight pediatric deaths reported
Monday, February 04, 2013

Medroxyprogesterone Acetate Linked to Immune Suppression
May affect responses to HIV by blocking HIV-1 coreceptors, increasing rate of HIV-1 replication
Friday, February 01, 2013

Tadalafil Improves Ejaculatory, Orgasmic Function
After treatment, residual ejaculatory or orgasmic dysfunction negatively impact sexual satisfaction
Friday, February 01, 2013

Low Diuretic Use in Home Care for Blacks With Hypertension
Despite guidelines, majority of blacks with uncontrolled hypertension don't receive diuretics
Thursday, January 31, 2013

Brain Activity Predicts Response to Scopolamine
Neural response in visual cortex after emotional stimuli predicts response in major depression
Thursday, January 31, 2013

CDC: Non-Flu Adult Vaccination Rates Largely Unchanged
Vaccination rates in 2011 and 2010 similar, except for modest increases in HPV in women, Tdap
Thursday, January 31, 2013

Peds Rotavirus Vaccine Offers Indirect Protection for Adults
About 50 percent drop in rotavirus prevalence for unvaccinated adults during peak disease season
Thursday, January 31, 2013

Kynamro Approved for Genetic Condition Tied to Cholesterol
Injection is an addition to lipid-lowering meds, diet in homozygous familial hypercholesterolemia
Wednesday, January 30, 2013

Single, Fractional Dose of Polio Vaccine Induces Priming
Seroconversion noted in more than 90 percent of infants, with two full or fractional doses
Wednesday, January 30, 2013

Parents Not Too Concerned About Child Abuse of Pain Meds
New poll shows that parents have lukewarm support for most policies to discourage misuse
Wednesday, January 30, 2013

Early Palliative Care in Lung CA Focuses on Coping, Symptoms
During critical time points or progression, palliative care emphasizes psychosocial aspects
Wednesday, January 30, 2013

Study Confirms Prolongation of QT Interval With Citalopram
Dose-response association with QTc prolongation for citalopram, escitalopram, amitriptyline
Wednesday, January 30, 2013

Moxifloxacin Monotherapy Equivalent to Antibiotic Combo
Findings among adult, febrile neutropenic cancer patients at low risk for complications
Wednesday, January 30, 2013

Bile Acid Sequestrant Reduces Glucose Concentration in T2DM
Colesevelam cuts fasting, postprandial glucose in subjects taking metformin; no effect on insulin
Wednesday, January 30, 2013

Flu Vaccine Safe in Children With Severe Egg Allergy
Single dose safe even in children with a history of anaphylaxis
Wednesday, January 30, 2013

Some Dietary Interventions Improve ADHD Symptoms
Fatty acid supplementation, elimination of artificial food colorings have positive effects
Wednesday, January 30, 2013

T1DM Insulin Intensification Patterns, Outcomes Studied
In youth studied, sociodemographics impact odds of switch; better outcomes with more intensive regimens
Tuesday, January 29, 2013

Even Correctly-Administered NSAIDS Can Cause AKI in Kids
Young children with NSAID-induced acute kidney injury may have more severe disease
Tuesday, January 29, 2013

Low Rate of Prostate Cancer Diagnosis After REDUCE
Over two-year follow-up, more cancers detected in men in dutasteride arm versus placebo arm
Tuesday, January 29, 2013

Placebo Often Effective for Treating Headache in Children
Second study suggests innovative trial strategies needed to reduce the placebo response rate
Tuesday, January 29, 2013

ER Visits Up for Misuse of ADHD Stimulants by Young Adults
Increase in number of visits among young adults, visits involving nonmedical use for ADHD meds
Tuesday, January 29, 2013

AAP Releases 2013 Child, Teen Immunization Schedule
2013 five-page format includes single schedule for children aged 0 to 18 years
Monday, January 28, 2013

Prehospital Antiplatelets Improve Graft Intervention Outcomes
Linked to fewer major adverse cardiac events after saphenous vein graft intervention
Monday, January 28, 2013

FDA: Three New Treatments Approved for Type 2 Diabetes
Nesina, Kazano, and Oseni, all based on alogliptin, approved for use with diet and exercise
Monday, January 28, 2013

FDA Panel Votes for Tougher Restrictions on Hydrocodone
Panel votes in favor of moving hydrocodone combo products into Schedule II category
Friday, January 25, 2013

Folic Acid Supplementation Has No Effect on Cancer Incidence
Over five years of supplementation, no significant effect on overall, site-specific cancer incidence
Friday, January 25, 2013

Marked Geographic Variation in Mental Health Medication Use
Clusters identified with elevated likelihood of antidepressant, antipsychotic, stimulant use
Friday, January 25, 2013

Physician Education Ups Communication for New Meds
Patients rate the new medication information transfer higher for docs in intervention group
Thursday, January 24, 2013

Peginesatide Safe for Anemia in Patients Undergoing Dialysis
Second study shows cardiovascular events and mortality up in patients not undergoing dialysis
Wednesday, January 23, 2013

Smoking Cuts Life Expectancy by More Than 10 Years
Can be partially reversed by quitting smoking
Wednesday, January 23, 2013

Fetal Exposure to Valproate Linked to Lower IQ at Age 6
Exposure to high doses of valproate, not other antiepileptics, linked to reduced cognitive abilities
Wednesday, January 23, 2013

FDA Approves Botox for Overactive Bladder
When patients don't respond to standard treatments
Tuesday, January 22, 2013

Aspirin Ups Risk of Age-Related Macular Degeneration
Association independent of cardiovascular disease, smoking, other risk factors
Tuesday, January 22, 2013

FDA: First Skin Patch Approved to Treat Migraines
Battery-powered transdermal system delivers sumatriptan; provides headache, nausea relief
Tuesday, January 22, 2013

Perceived Weight Gain Accurate for New Contraceptive Users
Implant users and depot medroxyprogesterone acetate users more likely to report weight gain
Tuesday, January 22, 2013

Most With C. difficile Receive Unnecessary Antimicrobials
One-quarter of patients with recent C. difficile infection received only unnecessary antibiotics
Monday, January 21, 2013

CDC: Flu Activity Continues to Be High Across the United States
Activity decreased in some areas during the second week of January
Friday, January 18, 2013

Efforts Failed to Up Primary Care, Rural Resident Training
Net growth in primary care training, but outpaced by growth in non-primary care training
Friday, January 18, 2013

Differences in Care for E-Visits, Office Visits for Sinusitis, UTI
Follow-up similar with both visits; more antibiotics prescribed, less preventive care with e-visits
Thursday, January 17, 2013

FDA: Flublok Approved to Prevent Seasonal Influenza
New vaccine doesn't use flu virus or eggs; could speed up production
Thursday, January 17, 2013

Short Course of ART Therapy Delays HIV Progression
Second study shows later initiation of ART decreases likelihood of CD4+ T-cell recovery
Thursday, January 17, 2013

Influenza Burden Remains High in Young Children
Less than 45 percent of children vaccinated despite expanded recommendations
Thursday, January 17, 2013

Donor Fecal Infusion Effective for C. difficile Infection
Fecal infusion more effective for recurrent infection than vancomycin with, without bowel lavage
Wednesday, January 16, 2013

Influenza Vaccine in Pregnancy May Reduce Fetal Deaths
Decreased diagnosis of influenza and no increase in fetal mortality with maternal vaccination
Wednesday, January 16, 2013

Even Brief Interruptions Dramatically Increase Errors
Error rate doubled or tripled in response to brief interruptions of only 2.8 to 4.4 seconds
Wednesday, January 16, 2013

Family Docs Are Early Adopters of Electronic Health Records
Sixty-eight percent currently use EHR systems; likely to surpass 80 percent by 2013
Wednesday, January 16, 2013

Alkylating Agent Linked to Therapy-Related Leukemia
Significant reductions seen with successive generations of Hodgkin's lymphoma therapy
Tuesday, January 15, 2013

Most Newly Approved Biologics Studied in Peds Population
Majority are currently labeled for pediatric use or involved in trial; similar findings for vaccines
Tuesday, January 15, 2013

Generic Three-Pill HIV Regimen Could Result in Big Savings
Increased lifetime costs of $42,500 with use of branded ART versus generic-based regimen
Tuesday, January 15, 2013

Decision Support Reduces Antibiotic Usage for Bronchitis
Similar results seen with print-based versus computer-assisted support strategies
Tuesday, January 15, 2013

Certain Online Behaviors of Docs Warrant Investigation
Consensus in seven of ten vignettes; outcome less clear for other doc online behavior scenarios
Monday, January 14, 2013

AAN: Cognitive Decline With Early-Age Surgical Menopause
Increased duration of hormone replacement therapy use linked to slower global decline
Monday, January 14, 2013

Top Five Issues for Docs and Patients Identified for 2013
Issues include access to care, physician shortages, preparation for 30 million new patients
Monday, January 14, 2013

Use of Beta-Blockers Tied to Improved Lung Cancer Survival
Overall, distant metastasis-free, and disease-free survival all improved for patients with NSCLC
Friday, January 11, 2013

CDC: Flu Activity Remains High in the United States
Early vaccine effectiveness estimates indicate moderate protection against the flu
Friday, January 11, 2013

Insulin LY2605541 Tops Glargine for Glycemic Control in T1DM
Better glycemic control, reductions in nocturnal hypoglycemia, weight, mealtime insulin dose
Friday, January 11, 2013

Malaria Drug Association With Hemolytic Anemia Unclear
CDC recommends following patients treated with artesunate for a month
Friday, January 11, 2013

National U.S. Health Care Spending Relatively Stable
But during 2011, personal health care spending growth accelerated
Friday, January 11, 2013

Etanercept Seems Beneficial in Partial Spinal Cord Injury
In rabbits, etanercept correlates with enhanced clinical and electrophysiological recovery
Thursday, January 10, 2013

CDC: Rare Blood Disorder Found in Intravenous Drug Users
Thrombotic thrombocytopenic purpura seen in patients who dissolve and inject oral pain medication
Thursday, January 10, 2013

Rate of Non-Medical Use of Rx Pain Meds 4.6 Percent
Considerable variation seen between states, from 3.6 percent in Iowa to 6.4 percent in Oregon
Thursday, January 10, 2013

SPIRIT 2013 Clinical Trial Protocol Guidelines Issued
Thirty-three-item SPIRIT checklist will serve as guideline for the minimum content of clinical trial
Thursday, January 10, 2013

FDA: Draft Guidance Issued on Abuse-Deterrent Opioids
To assist industry in developing new formulations of opioid drugs with abuse-deterrent properties
Wednesday, January 09, 2013

Two HTN Meds Plus NSAIDs Ups Acute Kidney Injury Risk
Risk up with use of diuretic and ACE inhibitor or angiotensin receptor blocker, plus NSAID
Wednesday, January 09, 2013

Acetaminophen Cuts Post-Op Morphine Use in Infants
Significant reduction in morphine requirements over 48 hours after major surgery
Wednesday, January 09, 2013

Vitamin D Does Not Improve Knee OA Progression, Symptoms
Supplementation to raise levels above 36 ng/mL has no impact on knee pain, cartilage volume loss
Wednesday, January 09, 2013

Failure Rate of Cefixime for N. gonorrhoeae Infection Explored
Increased risk of clinical treatment failure with minimum inhibitory concentration of ≥0.12 µg/mL
Tuesday, January 08, 2013

Number of Adults Using Walk-in Retail Clinics Increasing
Most users satisfied with care; but many are reluctant to use for more serious conditions
Tuesday, January 08, 2013

Methotrexate Offers Lasting Benefit in Juvenile Scleroderma
Clinical remission maintained for mean of 25 months for 72.9 percent of responders
Tuesday, January 08, 2013

Health Care Use Dropped Among All During Recession
Little evidence of racial or ethnic disparities, except for fewer physician visits for Hispanics
Tuesday, January 08, 2013

Metformin Cuts Cardio Events in High-Risk Type 2 Diabetes
Three-year treatment with metformin reduces cardiovascular events more than glipizide
Monday, January 07, 2013

Low Rates of High Platelet Reactivity With Prasugrel Tx
Low rates of HPR, ischemic events, major bleeds with prasrugel in acute coronary syndromes
Monday, January 07, 2013

Shared Savings May Promote Care Coordination Entity Use
Sharing savings with dually eligible patients may foster enrollment in coordinated care entities
Monday, January 07, 2013

CDC: Influenza Activity Increasing Across the U.S.
Proportion of deaths attributed to pneumonia and influenza below epidemic threshold
Friday, January 04, 2013

Nifedipine-Maintained Tocolysis No Benefit in Perinatal Outcomes
For threatened preterm labor, maintenance use of nifedipine not significantly better than placebo
Friday, January 04, 2013

Patient-Doctor Communication Affects Medication Adherence
Poorer communication ratings tied to lower adherence, especially for hypoglycemic medications
Friday, January 04, 2013

Distributing Naloxone to Heroin Users Likely Cost-Effective
Scenarios show lay administration would be cost-effective, even under conservative assumptions
Friday, January 04, 2013

Nurse-Led Monitoring Improves Cancer-Related Fatigue
Protocolized patient-tailored treatment of physical symptoms improves fatigue in advanced cancer
Friday, January 04, 2013

High-Dose Flu Vaccine Better Protects HIV-Infected Adults
Higher seroprotection for H1N1, H3N2, influenza B strains with high-dose versus standard-dose
Thursday, January 03, 2013

Eliquis Approved for People With Non-Valvular Atrial Fibrillation
To help prevent stroke and deadly blood clots
Thursday, January 03, 2013

Fracture Risk Down With Adherence to Bisphosphonates
Second study shows more than half of U.S. vets with rheumatoid arthritis are non-adherent
Thursday, January 03, 2013

Association Between Health Care Cost, Quality Inconsistent
Review of 61 studies shows inconsistent evidence for the direction of the association
Thursday, January 03, 2013

Interferon-Free Therapies for Hep C Virus Look Promising
Sofosbuvir plus ribavirin and ABT-450/ritonavir, ABT-333, ribavirin combos seem effective
Wednesday, January 02, 2013

No Significant Link for Stillbirth, Maternal Antidepressant Use
Certain maternal characteristics can account for increased deaths seen with SSRI use
Wednesday, January 02, 2013

Sirturo Approved for Multi-Drug Resistant Tuberculosis
Millions still contract the infectious disease each year
Wednesday, January 02, 2013

Fulyzaq Approved for ART-Related Diarrhea in HIV/AIDS
Not for HIV/AIDS patients with diarrhea due to infection or gastrointestinal disorder
Wednesday, January 02, 2013

House Joins Senate to Avert Medicare Cuts
U.S. health care could be significantly affected by failure to reach 'fiscal cliff' agreement
Wednesday, January 02, 2013

Administering Chemo Ups Income for Non-Salaried Oncologists
More research needed to understand impact of financial incentives on cost, quality of care
Wednesday, January 02, 2013

Teen Vitamin D Intake Not Related to Adult RA or SLE Risk
No link between dietary vitamin D intake during adolescence, rheumatoid arthritis, lupus risk
Thursday, December 27, 2012

Indicators Show Little Change in Overuse of Ambulatory Care
In U.S., improvement in six of nine underuse indicators; two of 11 overuse indicators
Thursday, December 27, 2012

Understanding of Infantile Hemangiomas Is Improving
New treatment options are available to minimize functional deformity, but risks need to be assessed
Thursday, December 27, 2012

Fertility Drugs Not Linked to Uterine Cancer Recurrence
Five-year disease-free survival similar for women who did or did not receive fertility drugs
Wednesday, December 26, 2012

FDA Recommends Against Drug to Treat Chronic Fatigue Syndrome
Advisory committee considered new analysis of trial data originally submitted in 2009
Friday, December 21, 2012

Varizig Approved to Reduce Chickenpox Symptoms
To be used within four days of exposure
Friday, December 21, 2012

FDA Expands Tamiflu Use to Treat Babies Under 1 Year Old
However, dose must be calibrated to weight
Friday, December 21, 2012

Data Suggest Smoking Doesn't Impact RA Treatment Response
No differences in mean disease activity score in 28 joints based on smoking status
Thursday, December 20, 2012

Fatty Acids Don't Reduce Atrial Fibrillation Recurrence
No significant difference from placebo for other outcomes, including stroke, MI, heart failure
Thursday, December 20, 2012

Metformin Treatment Beneficial for Obese Children, Teens
Twice-daily metformin improved body mass index SD score, metabolic risk factors, adipokines
Thursday, December 20, 2012

Two Drugs Promising for Juvenile Idiopathic Arthritis Treatment
Two studies show patients respond well to tocilizumab and canakinumab
Wednesday, December 19, 2012

Substantial Morbidity, Mortality From Fungus-Tainted Steroid
In 19 states, 590 cases of infection, 37 deaths tied to three lots of contaminated glucocorticoid
Wednesday, December 19, 2012

Vertex Announces Boxed Warning on Hepatitis C Drug
Decision prompted by reports of fatal cases of serious skin reactions with telaprevir treatment
Wednesday, December 19, 2012

Denosumab Does Not Delay Nonvertebral Fracture Healing
No delay of healing or contribution to other complications for postmenopausal women
Wednesday, December 19, 2012

Amoxicillin of Little Benefit in Lower-Respiratory Infection
Duration of symptoms, symptom severity not improved with amoxicillin in adults or older adults
Wednesday, December 19, 2012

Aspirin Use 10 Years Prior Tied to Incidence of Late AMD
Aspirin use linked to increased incidence of late, neovascular age-related macular degeneration
Tuesday, December 18, 2012

Adalimumab Relieves Hidradenitis Suppurativa
Once-weekly adalimumab reduces pain, inflammation in moderate-to-severe disease
Tuesday, December 18, 2012

Workplace Bullying Linked to Psychotropic Medication Use
Experiencing or observing workplace bullying increase need for subsequent psychotropic meds
Tuesday, December 18, 2012

AAP Urges United Nations Not to Ban Thimerosal in Vaccines
No evidence of harm from thimerosal; ban may reduce vaccine rates in developing countries
Monday, December 17, 2012

Health Care Satisfaction Rated As High by Unacculturated Hispanics
Unacculturated or biculturated Hispanics give higher ratings for health care experiences
Monday, December 17, 2012

Tenofovir Effectively Treats Adolescents With Chronic HBV
Once-daily tenofovir treatment is effective and well tolerated, regardless of prior treatment
Friday, December 14, 2012

Imeglimin Beneficial As Add-On to Metformin in T2DM
As add-on therapy, new oral agent improves glycemic control; generally well tolerated
Thursday, December 13, 2012

Racial/Ethnic Differences ID'd in HTN Medication Behaviors
Differences may be mediated by health system factors such as co-payment, mail order pharmacies
Thursday, December 13, 2012

Immunogenicity Strongly Impacts Response to Adalimumab in RA
For anti-TNF therapy-naive patients, overall efficacy similar for etanercept, adalimumab
Thursday, December 13, 2012

~40 Percent of Cancer Patients Receive Opioids at End of Life
In the U.K., patients older than 60 less likely to receive prescription versus those younger than 50
Thursday, December 13, 2012

FDA: Chantix May Raise Risk for Cardiovascular Events
FDA advises consideration of risks and benefits
Thursday, December 13, 2012

Teduglutide Seems Effective, Safe for Short Bowel Syndrome
Leads to a significant reduction in parenteral support compared with placebo
Wednesday, December 12, 2012

NSAIDs Exacerbate Exercise-Induced Small Intestinal Injury
NSAIDs induce gut barrier dysfunction in healthy athletes; extent of injury tied to barrier dysfunction
Wednesday, December 12, 2012

Any Amount of Smoking Ups Sudden Cardiac Death in Women
Dose-dependent relationship; even small-to-moderate amounts of smoking increase SCD risk
Wednesday, December 12, 2012

Benzodiazepines Linked to Higher Risk of Pneumonia
Benzodiazepine use also linked to increased 30-day and long-term mortality following pneumonia
Tuesday, December 11, 2012

Menopause Weight Gain May Up Breast Tumor Growth in Obese
Excess nutrients deposited in tumors of obese rats; tumors overexpress progesterone receptor
Tuesday, December 11, 2012

ASH: Extended Apixaban Cuts Risk of Recurrent VTE
Extending anticoagulation with apixaban 2.5 or 5 mg cuts risk without increasing major bleeding
Monday, December 10, 2012

Raised Risk of Ischemic Stroke in Women With A-Fib Explored
Gender-specific risk related in part to percent time in therapeutic range for warfarin
Monday, December 10, 2012

Concerns for Long-Term Safety of Antipsychotics in Over 40s
Lack of effectiveness, high incidence of side effects found for four common atypical antipsychotics
Friday, December 07, 2012

No Evidence That Doping Enhances Athletic Performance
Literature review fails to find evidence that rHuEPO enhances performance
Friday, December 07, 2012

Synergistic Risk of VTE for Women With PCOS Using the Pill
More than two-fold increased risk for women with PCOS who use combined oral contraceptives
Friday, December 07, 2012

Health Care Law Boosts Savings on Meds for Medicare Recipients
Savings on prescription drugs has reached $5.1 billion; for more than 5.8 million beneficiaries
Friday, December 07, 2012

Socioeconomic Status Affects Cancer Trial Referrals
Patients of lower socioeconomic status less likely to be referred to early-phase cancer trials
Thursday, December 06, 2012

Impact of HTN Meds on Cardio Risk Affected by Body Size
Thiazide-based treatment better for obese; amlodipine therapy effective across all BMI groups
Thursday, December 06, 2012

FDA Requests Removal of Generic Budeprion XL 300 mg
In head-to-head study, Budeprion XL 300 mg not bioequivalent to brand-name Wellbutrin XL 300 mg
Wednesday, December 05, 2012

FDA: Zofran 32-mg Dose Pulled From Market
The anti-nausea drug may cause serious heart problems at that dosage
Wednesday, December 05, 2012

Stimulant Still Available for Sale Despite FDA Action
DMAA marketed as a dietary supplement
Wednesday, December 05, 2012

Tetanus-Diphtheria-Pertussis Shot Deemed Safe for Seniors
No more adverse events seen with Tdap than with the Td vaccination in large study
Wednesday, December 05, 2012

Psychotropics Seem to Be Appropriately Prescribed to Teens
14.2 percent of sample of U.S. teens report being treated with psychotropic meds in past year
Tuesday, December 04, 2012

CDC: Flu Season Has Started and Hitting Hard
Levels of flu activity continue to increase nationally
Tuesday, December 04, 2012

Topical Simvastatin Accelerates Wound Healing in Diabetes
Acceleration is due to direct effect on lymphatics and indirect effects via macrophages
Monday, December 03, 2012

Epidural Steroid Shot Has Adverse Effect on Bone Density
Findings seen in postmenopausal women being treated for pain associated with radiculopathy
Monday, December 03, 2012

Recent Increase in Adverse TMP-SMX Reactions in Children
Significant increase from 2000 to 2009; coincident with increased use for skin, soft tissue infections
Monday, December 03, 2012

Fetal NSAID Exposure Not Tied to Persistent Pulmonary HTN
Neither NSAIDS overall, nor ibuprofen exposure tied to increased risk of hypertension of newborn
Monday, December 03, 2012

Increasing Number of Workers in Self-Insured Health Plans
In 2011, 58.5 percent with health coverage self-insured; increase driven by large employers
Monday, December 03, 2012

Model Predicts Flu Season Peak Seven Weeks in Advance
Based on data assimilation technique using data from the Web, flu peak predicted for New York City
Friday, November 30, 2012

Aspirin Use Cuts Risk of Hepatocellular Carcinoma
Nonaspirin NSAIDs, aspirin cut death due to chronic liver disease
Thursday, November 29, 2012

Orexin Receptor Antagonist Improves Sleep in Insomnia
Dose-related improvements in sleep efficiency, sleep induction, and maintenance
Thursday, November 29, 2012

Cigarette Tax Would Cost Federal Government in Long Term
Initial drop in spending to 2021, but increased longevity would ultimately increase spending
Wednesday, November 28, 2012

Political Leaders Face Voter Opposition to Medicare Cuts
Voter poll analysis portends conflict in ACA implementation
Wednesday, November 28, 2012

Digoxin Found to Increase Mortality in A-Fib Patients
Digoxin associated with a significant increase in deaths in patients with atrial fibrillation
Wednesday, November 28, 2012

Study Confirms Waning Immunity With Time Post-Pertussis Vaccine
Children with pertussis in California outbreak were less likely to have received five-dose DTaP series
Wednesday, November 28, 2012

Adding Fitness to Statin Rx Significantly Improves Mortality
In dyslipidemia, combo of statins, fitness results in greater reduction in mortality risk than either alone
Wednesday, November 28, 2012

Warfarin D/C Within 180 Days Post-Surgery May Up Mortality
CV death risk up with warfarin discontinuation within six months of valve replacement
Tuesday, November 27, 2012

Survival Benefit of Two Heart Failure Therapies Re-Examined
Studies examine aldosterone antagonists and renin-angiotensin system antagonists
Tuesday, November 27, 2012

Doc Earnings Growth Lags Behind Other Health Professionals
Adjusted physician earnings dropped by 1.6 percent from 1996-2000 to 2006-2010
Tuesday, November 27, 2012

Zolpidem Linked to Increased Risk of Inpatient Falls
Association persists after adjustment for multiple variables including age, insomnia, delirium
Tuesday, November 27, 2012

Growing Number of Drugs Possibly Inhibited by Grapefruit
All drugs orally administered; have low-to-intermediate bioavailability; metabolized by CYP3A4
Tuesday, November 27, 2012

Hemorrhage Rates Highest Within 30 Days of Warfarin Tx
For older patients with atrial fibrillation, rates highest in first 30 days of treatment
Monday, November 26, 2012

Ranbaxy Issues Recall of 41 Batches of Atorvastatin
Voluntary recall issued for specific batches of 10-, 20-, 40-mg atorvastatin calcium
Monday, November 26, 2012

AAP Addresses Emergency Contraception for Teens
Policy statement encourages pediatricians to give emergency contraception Rx in advance
Monday, November 26, 2012

Growth in Health Benefit Cost Per Employee Slowed in 2012
Workforce health management is strategy to cut costs, with incentives offered to up participation
Friday, November 23, 2012

For Patients With ADHD, Lower Criminality Rates With Med Use
Rates significantly down for men, women with ADHD receiving meds versus nonmedication periods
Wednesday, November 21, 2012

ACOG Advises Over-the-Counter Access for Oral Contraceptives
ACOG recommends over-the-counter availability to improve access to and use of oral contraceptives
Wednesday, November 21, 2012

Nearly 40 Percent of Adults Take Dietary Supplements
Most would continue taking them even if they were shown to be ineffective
Wednesday, November 21, 2012

Aspirin Resistance Ups Severity in Acute Ischemic Stroke
Increased stroke severity, infarct size linked to aspirin resistance in acute ischemic stroke
Wednesday, November 21, 2012

Testosterone Doesn't Add to Erectile Response With Sildenafil
Sildenafil + testosterone not superior for men with erectile dysfunction, low testosterone
Monday, November 19, 2012

Personality Traits Explain Some of Placebo Analgesic Effect
Resilient people have activation of endogenous painkillers in response to placebo after pain
Monday, November 19, 2012

Mental Illness, Job Stress Both Factors in Physician Suicides
Docs more likely to have antipsychotics, barbiturates, not antidepressants on toxicology testing
Friday, November 16, 2012

Optimal Dose Suggested for Dasatinib in Ovarian Cancer
Dasatinib in combination with paclitaxel and carboplatin shows some efficacy
Friday, November 16, 2012

Diltiazem Relieves Capecitabine-Induced Chest Pain
Prophylaxis with diltiazem prevents chest pain, allowing patients to tolerate capecitabine
Friday, November 16, 2012

Direct-to-Consumer Advertising Found Beneficial for Certain Meds
DTCA linked to increase in appropriate prescriptions of aromatase inhibitors for breast cancer
Friday, November 16, 2012

Ten-Valent Pneumococcal Conjugate Vaccine Effective
Different vaccine schedules are effective, including 2+1 schedule in infants
Friday, November 16, 2012

Trastuzumab Ups Cardiac Risk for Older Women With Breast Cancer
Treatment increases rates of heart failure, cardiomyopathy in early-stage breast cancer
Thursday, November 15, 2012

Study Provides Justification for L-DOPA in Angelman Syndrome
Dopamine release up in mesolimbic pathway, down in nigrostriatal pathway with L-DOPA treatment
Thursday, November 15, 2012

Venous Thromboembolism Risk Up With Cisplatin-Based Chemo
Meta-analysis shows elevated relative risk for cisplatin-treated patients with advanced solid tumors
Wednesday, November 14, 2012

Efficacy of Corticosteroid Injection for Sciatica Reviewed
Meta-analysis shows small short-term relief for leg pain, disability; however, little long-term benefit
Tuesday, November 13, 2012

Statin Use at Cancer Diagnosis Linked to Lower Mortality
All cause, cancer-related mortality down by about 15 percent for statin users at time of diagnosis
Wednesday, November 07, 2012

Triptorelin Doesn't Avert Early Ovarian Failure in Lymphoma
However, gonadotropin-releasing hormone agonist may protect ovarian reserve after chemotherapy
Wednesday, November 07, 2012

Guideline-Concordant Tx Cuts Mortality in Schizophrenia
Mortality also decreased with use of anti-Parkinson's medications, mental health visits
Wednesday, November 07, 2012

AHA: Peri-Op Omega-3s Don't Reduce Atrial Fibrillation
No reduction in the risk of a-fib for patients receiving peri-cardiac-op fish oil versus placebo
Wednesday, November 07, 2012

AHA: AMG145 Lowers LDL Levels in Statin-Intolerant
Subcutaneously administered monoclonal antibody to PCSK9 efficacious and tolerable
Wednesday, November 07, 2012

Study Compares Exenatide, Liraglutide for Type 2 Diabetes
Greater drop in glycated hemoglobin with liraglutide; adverse events occur less often with exenatide
Wednesday, November 07, 2012

AHA: Multivitamins Don't Reduce Cardiovascular Events
No decrease in MI, stroke, mortality in U.S. physicians followed for more than a decade
Tuesday, November 06, 2012

AHA: Social Cocaine Use Tied to Environment for Heart Attack
Users have higher systolic blood pressure, stiffer arteries, and thicker heart muscle walls
Tuesday, November 06, 2012

Sulfonylureas Up Cardio Events Versus Metformin
Sulfonylureas for initial treatment of diabetes linked to increase in composite of MI, stroke, death
Tuesday, November 06, 2012

Antirheumatic Drugs Have Minor Effect on Preeclampsia Risk
Increased risk for women with SLE; nonsignificant increased risk for DMARD users in pregnancy
Tuesday, November 06, 2012

AHA: Aspirin Doesn't Reduce Recurrence After First VTE
But results in significant reduction in rate of major vascular events, with improved net clinical benefit
Monday, November 05, 2012

FDA Approves Expanded Use of Xarelto
Use expanded to include treatment of deep vein thrombosis or pulmonary embolism
Monday, November 05, 2012

Drug Combo Active in Breast Cancer With Brain Metastases
Lapatinib plus capecitabine active for women with advanced HER2-positive breast cancer
Friday, November 02, 2012

Combo Therapy Can Be First-Line Approach in Manic Episodes
Combination therapy superior for efficacy, relapse prevention, with acceptable safety profile
Thursday, November 01, 2012

NSAIDS Don't Affect C-Reactive Protein Levels in RA Patients
Stratified analysis of specific NSAIDs show significant effect; naproxen tied to decrease in CRP
Thursday, November 01, 2012

Antidepressants Linked to Pregnancy Risks in Infertility Tx
No evidence of improved pregnancy outcome; counseling may be effective for depressive symptoms
Thursday, November 01, 2012

Anticoagulation Therapy Appears to Be Safe After TAVI
No increased risk of bleeding or other adverse outcome after receiving anticoagulant therapy
Thursday, November 01, 2012

Single Topical Ivermectin Head Lice Treatment Very Effective
Ten-minute, at-home ivermectin treatment eliminates lice in nearly all patients by the next day
Wednesday, October 31, 2012

Once-Yearly Zoledronic Acid Benefits Men With Osteoporosis
Significant drop in risk of new vertebral fractures, increased bone density, lower bone turnover
Wednesday, October 31, 2012

FDA: Ameridose Issues Voluntary Recall of All Products
All unexpired products should be returned to manufacturer
Wednesday, October 31, 2012

Only Omega-3s From Fish Tied to Lower Cerebrovascular Risk
Omega-3 fatty acids measured as circulating biomarkers, supplements not linked to lower risk
Wednesday, October 31, 2012

Latrepirdine Not Effective in Huntington's Disease
Six months of treatment does not improve cognition in patients with mild-to-moderate disease
Wednesday, October 31, 2012

U.S. Medicare Spending on Elderly Has Outpaced Canada's
Growth three times faster in the U.S., while Canada offers more comprehensive benefits
Tuesday, October 30, 2012

Resveratrol Has No Metabolic Benefit for Non-Obese Women
Does not affect its putative targets in fat or muscle in women with normal glucose tolerance
Tuesday, October 30, 2012

Buspirone Improves Symptoms in Functional Dyspepsia
Reduces symptom severity, slows liquid gastric emptying, and enhances gastric accommodation
Monday, October 29, 2012

More Intensive Chemo Ups Survival in Ewing Sarcoma
No increased toxicity with increasing chemo from every three weeks to every two weeks
Monday, October 29, 2012

Insulin Sensitivity Normally Highest After Breakfast
Increased beta-cell responsiveness to glucose, disposition index; lower hepatic insulin extraction
Friday, October 26, 2012

Meta-Analysis: Antivirals Reduce Risk of Liver Cancer in Hep C
Meta-analysis shows preventive effect more pronounced for virological responders
Thursday, October 25, 2012

Timing of Hormone Therapy Use Impacts Alzheimer's Risk
Women who start hormone therapy within five years of menopause have 30 percent reduced risk
Thursday, October 25, 2012

Aspirin Improves Survival for CRC With PIK3CA Mutation
Use of aspirin after diagnosis ups cancer-specific, overall survival for patients with mutated PIK3CA
Wednesday, October 24, 2012

Terminal Cancer Patients May Have Erroneous Chemo Beliefs
Patients who rate communication with their doctor favorably more likely to have inaccurate beliefs
Wednesday, October 24, 2012

Genuine Very Large Effects in Trials Rare in Medicine
Very large effects typically seen in small trials and diminish subsequently; seldom address mortality
Tuesday, October 23, 2012

Antihypertensive Medication Use, BP Control Up in U.S.
Multiple agent use up from 2001 to 2010; linked to increased likelihood of blood pressure control
Tuesday, October 23, 2012

TNF Inhibitor Use Doesn't Up Short-Term Cancer Incidence
In rheumatoid arthritis, inflammatory bowel disease, psoriasis, or psoriatic arthritis
Monday, October 22, 2012

HRT Not Recommended for Prevention of Chronic Conditions
Task force concludes that moderate harms of hormone replacement outweigh potential benefits
Monday, October 22, 2012

Higher Calcium Intake May Lower Risk of Hyperparathyroidism
Increased dietary calcium lowers risk of primary hyperparathyroidism in women
Friday, October 19, 2012

Stroke Risk Up With Serotonin Reuptake Inhibitor Use
Risk of intracerebral and intracranial hemorrhage is increased with exposure to SSRIs
Thursday, October 18, 2012

Linezolid Beneficial in Drug-Resistant Tuberculosis
Addition to background therapy effectively achieves culture conversion; high rate of adverse events
Thursday, October 18, 2012

AACR: Multivitamins Linked to Modest Drop in Cancer in Men
Nonsignificant trend for site-specific cancer reduction seen with daily multivitamin use by older men
Wednesday, October 17, 2012

Alzheimer's Symptoms Relapse Risk High After Halting Drug
Psychotic or aggressive patients responding to antipsychotic drugs at risk if drug is discontinued
Wednesday, October 17, 2012

AAPS: Intravaginal Ring Releases HIV Drug Over 90 Days
Tenofovir released steadily; similar to or better than gel administration in sheep model
Wednesday, October 17, 2012

Lipid Profiles Improved in Past Two Decades in United States
Improvements seen even in the obese and those not taking lipid-lowering drugs
Tuesday, October 16, 2012

High-Dose Vitamins Don't Halt HIV Progression, Death
High-dose supplement not beneficial for patients in Tanzania initiating HAART; may increase ALT levels
Tuesday, October 16, 2012

ASA: Illicit Drug Abuse Down, Prescription Drug Abuse Up
Emergency room data from 2007 to 2009 shows decreases larger in magnitude than increases
Tuesday, October 16, 2012

Zonisamide 400 mg Enhances Weight Loss for Obese
But high incidence of gastrointestinal, nervous system, and psychiatric adverse events
Monday, October 15, 2012

B-Vitamin Supplement Doesn't Lower Colorectal Cancer Risk
Combination of folic acid plus vitamins B6, B12 doesn't lower adenoma risk for high-risk women
Monday, October 15, 2012

Methotrexate Use Linked to Reduced Mortality in RA
Findings for methotrexate use of more than one year in cohort of patients followed for 25 years
Friday, October 12, 2012

Tadalafil Effective, Safe in Complete Erectile Dysfunction
Intercourse success rates of 32 to 46 percent achieved with tadalafil, with good tolerability
Friday, October 12, 2012

Seniors Overspending on Prescription Drug Plans
Medicare Part D beneficiaries overspend by hundreds per year due to difficulty selecting plan
Friday, October 12, 2012

PCI Linked to Increased Platelet Reactivity
Increase observed after percutaneous coronary intervention despite antiplatelet therapy
Friday, October 12, 2012

Leflunomide Considered Safe, Effective for Psoriatic Arthritis
Improvements seen in joint scores, pain, fatigue, dactylitis, and skin disease
Friday, October 12, 2012

Use of More Costly Diabetes Medications Varies Widely
Even within integrated VA system with set formulary and utilization management tools
Thursday, October 11, 2012

Social Media Influences Youth Sexual Behavior in Short Term
Positive effect seen in condom usage at two months, but not six months
Thursday, October 11, 2012

Prior Alcohol Consumption Does Not Impair HCV Treatment
Pretreatment drinking patterns, total alcohol intake unrelated to sustained virological response
Thursday, October 11, 2012

Study Confirms Link Between Analgesic Use, Ovarian Cancer
Case-control study shows any analgesic, aspirin use may reduce risk of ovarian cancer
Thursday, October 11, 2012

HIV Status Doesn't Influence Hodgkin's Lymphoma Outcome
In patients treated with ABVD chemotherapy, despite more extensive disease, worse prognosis
Thursday, October 11, 2012

New Cervical Cancer Vaccine Targets HPV-Infected Women
Early studies show that vaccine is well tolerated, immunogenic for women with prior neoplasia
Wednesday, October 10, 2012

Diverse Forms of Distress Have Distinct Impact in Diabetes
Depressive symptoms affect self-care behaviors; diabetes-related distress impacts glycemic control
Wednesday, October 10, 2012

Long-Term Ranibizumab Beneficial for Macular Edema
Reduces mean foveal thickness, improves visual acuity, but significantly more injections required
Wednesday, October 10, 2012

Hormone Replacement Therapy Initiated Early Deemed Safe
Ten years of HRT linked to reduced risk of composite of mortality, heart failure, MI
Wednesday, October 10, 2012

Review Compares Effectiveness of Tocolytic Agents
Prostaglandin inhibitors and calcium channel blockers most effective for delaying delivery
Wednesday, October 10, 2012

Cannabis Relieves Muscle Stiffness in Multiple Sclerosis
Oral cannabis extract provides nearly twice the rate of relief of placebo; also beneficial for pain
Wednesday, October 10, 2012

Belimumab Deemed Safe for Long-Term Treatment of Lupus
Over four years of exposure, adverse events were stable or declined
Tuesday, October 09, 2012

Low-Dose Aspirin Use Shows Neuroprotective Effect in Women
In older women at high risk for cardiovascular disease taking daily low-dose aspirin over five years
Tuesday, October 09, 2012

Prenatal Psychotropic Meds Affect Infant Language
Maternal mood, exposure to SRIs affect development of infant speech perception
Monday, October 08, 2012

Free Birth Control Substantially Lowers Abortion Rate
Reduction in repeat abortions; abortions, teen pregnancies down versus national rates
Monday, October 08, 2012

Larger Study Confirms Statins' Role in Preventing Cardiac Events
Most persistent users have lower risk of acute cardiac events versus nonpersistent users
Friday, October 05, 2012

Lower Glaucoma Risk for Statin Users With Hyperlipidemia
Statin use lowers risk of open-angle glaucoma, progression to OAG, need for treatment
Thursday, October 04, 2012

Limiting the Problem of Missing Data Urged for Clinical Trials
Special report: analysis methods can not compensate for missing data, simple fixes ruled out
Wednesday, October 03, 2012

Mexiletine Shows Promise for Rare Nondystrophic Myotonias
Improvement in patient-reported severity score of stiffness and quality of life with mexiletine
Wednesday, October 03, 2012

Cherry Intake Linked to Lower Risk of Recurrent Gout Attacks
Cherries or cherry extract linked to lower risk; additive effect when combined with allopurinol
Wednesday, October 03, 2012

High-Dose Vitamin D Does Not Prevent or Treat Colds
No reductions in days missed from work, duration of symptoms, or cold severity
Tuesday, October 02, 2012

Study Finds β-Blockers May Not Reduce Cardiovascular Event Risk
Findings in observational study of stable patients with, without coronary artery disease, prior MI
Tuesday, October 02, 2012

New Guidelines Issued for Management of Gout
Two-part guidelines include approaches to hyperuricemia; therapy, prophylaxis for acute gout
Tuesday, October 02, 2012

No New Safety Concerns for Gardasil in Young Females
No additional safety problems detected since its approval in 2006
Tuesday, October 02, 2012

Sexual Dysfunction Common With Aromatase Inhibitors
Unsatisfactory sex life, low sexual interest for about half of postmenopausal breast cancer patients
Monday, October 01, 2012

Melatonin Effective for Sleep in Patients Taking β-Blockers
No rebound sleep disturbance observed after discontinuing melatonin
Monday, October 01, 2012

Benzodiazepine Use Linked to Increased Risk of Dementia
Link robust after adjustment, across pooled studies over time, in nested case-control study
Friday, September 28, 2012

Topical NSAIDs Effective for Chronic Musculoskeletal Pain
Equivalent to oral NSAIDs in efficacy but with fewer adverse gastrointestinal effects
Thursday, September 27, 2012

Efficacy of Black Cohosh for Menopausal Symptoms Unclear
Does not reduce frequency of hot flashes versus placebo; insufficient evidence regarding safety
Wednesday, September 26, 2012

Drugs Similar in Efficacy for Neuropathic Pain in Diabetes
Amitriptyline, duloxetine, and pregabalin reduce pain; differ in sleep quality, adverse effects
Wednesday, September 26, 2012

Antibiotic Use Varies by Season, Geographic Region for Elderly
In older adults, antibiotic use highest in South, lowest in West, particularly in winter months
Wednesday, September 26, 2012

Limited Evidence on Medication Use for Youth With Autism
Review IDs lack of evidence on medication use for 13- to 30-year-olds with autism spectrum disorder
Monday, September 24, 2012

Childhood Antibiotic Exposure Linked to Development of IBD
Earlier exposure during childhood tied to even greater risk of inflammatory bowel disease
Monday, September 24, 2012

Duration of Antiplatelet Drugs for Drug-Eluting Stents Studied
Two studies show similar rate of cardiac events with/without discontinuation during first year
Thursday, September 20, 2012

Sequential Oral, Topical Tacrolimus Benefits Dermatitis
Pilot study shows benefits in assessments of atopic dermatitis disease control
Thursday, September 20, 2012

Progestogens Not Effective in Multiple Gestations
Treatment prevents preterm birth in singleton pregnancies but not in multiple gestations
Tuesday, September 18, 2012

VTE Risk Varies by Hormone Therapy Formulation
Highest VTE risk associated with oral estrogen-progestin formulations with medroxyprogesterone
Tuesday, September 18, 2012

L-Carnitine Does Not Reduce Cancer-Related Fatigue
No relief for patients with invasive malignancies given L-carnitine supplementation 2 g/day for four weeks
Tuesday, September 18, 2012

Resuming Warfarin After GI Bleed Cuts Mortality
Benefits of lower risk of thrombosis and death outweigh risks of new gastrointestinal bleed
Tuesday, September 18, 2012

Nicotine Replacement Doesn't Increase Cardio Risk After ACS
In year after acute coronary syndromes, no increase seen in cardiovascular events with NRT
Monday, September 17, 2012

Antipsychotic Use Up Among U.S. Medicaid-Enrolled Youth
By 2007, youth with ADHD accounted for half of total antipsychotic use
Friday, September 14, 2012

Risk of Car Accidents Up With Antidepressant Use
Benzodiazepines and Z-drug use also increases odds of car accidents, but not antipsychotic use
Friday, September 14, 2012

Long-Term Finasteride Doesn't Impair Quality of Life
No negative effects for men randomized to receive finasteride to prevent prostate cancer
Thursday, September 13, 2012

Meta-Analysis: Acupuncture Reasonable Chronic Pain Option
Effective relief for back and neck pain, osteoarthritis, and chronic headache
Thursday, September 13, 2012

Advertising Changes After Drug Switch to Over-the-Counter
After switch from prescription, less presentation of potential harms, generic names omitted
Thursday, September 13, 2012

Persistence of Statin Use Linked to Decreased Cancer Risk
Significant reduction in risk of hematopoietic malignancies for those with most persistent use
Wednesday, September 12, 2012

No Superior Method of Adjusting Inhaled Steroids in Asthma
Time to treatment failure similar for physician-, biomarker-, symptom-based strategies
Tuesday, September 11, 2012

Review: Omega-3s Do Not Reduce Risk of Cardio Events
Meta-analysis of 20 studies shows no correlation with mortality, cardiac mortality, MI, stroke
Tuesday, September 11, 2012

Less Alzheimer's Pathology With Angiotensin Receptor Blocker Use
Autopsies show less amyloid deposition markers for angiotensin receptor blocker-treated patients
Tuesday, September 11, 2012

Antihypertensive Use in Pregnancy Increasing
Prevalence close to 5 percent; some medications contraindicated in pregnancy are still used
Monday, September 10, 2012

NSAID Use Ups Cardiovascular Risk Up to Five Years Post-MI
Increased risk of death and coronary death or recurrent MI for NSAID users versus nonusers
Monday, September 10, 2012

Early Prophylactic Tx Beneficial for Hypertrophic Cardiomyopathy
Beta blockers reduce exercise-triggered left ventricular outflow tract obstruction
Monday, September 10, 2012

Antiretrovirals Increasingly Used for HIV in the U.S.
Viral load has decreased and CD4 counts have increased in the past decade
Friday, September 07, 2012

Not All Docs/Nurses Want to Be Asked About Hand Hygiene
Few were asked in the past month; more than a quarter do not want patients to remind them
Friday, September 07, 2012

Bolus Epidural Fentanyl Cuts Post-Spinal Decompression Pain
Intraoperative bolus epidural fentanyl improves early pain without significant side effects
Thursday, September 06, 2012

Intermittent ADT Noninferior to Continuous ADT for Prostate CA
For men with rising PSA after radiotherapy, survival similar for continuous, intermittent therapy
Wednesday, September 05, 2012

Anthracycline, Trastuzumab for Breast CA Up Heart Failure Risk
Risk of heart failure and/or cardiomyopathy up for women with incident, invasive breast cancer
Wednesday, September 05, 2012

Clopidogrel After MI Less Effective in Diabetes Patients
Less reduction in risk of all-cause, cardiovascular death in patients with diabetes versus without
Wednesday, September 05, 2012

No Increased Risk of Cancer With Biologics in Rheumatoid Arthritis
Use of biologic response modifiers for at least 24 weeks doesn't up overall, specific malignancy risk
Tuesday, September 04, 2012

Addition of Tiotropium Effective in Poorly Controlled Asthma
Beneficial effect seen for patients with poorly controlled asthma despite standard therapy
Tuesday, September 04, 2012

New Drug Approved for Irritable Bowel, Chronic Constipation
Linzess sanctioned for cases that don't respond to conventional treatment
Thursday, August 30, 2012

Lower Prostate Cancer-Specific Death With Anticoagulant Use
Aspirin primarily contributes to reduction for localized cancer treated with prostatectomy, radiotherapy
Thursday, August 30, 2012

Lung Cancer Risk Unaffected by Metformin Use in Diabetes
In nested-case control analysis, risk of lung cancer not lower in metformin-treated type 2 diabetes
Thursday, August 30, 2012

Similar Rate of CV Events With Atenolol, Metoprolol Tartrate
Rates of incident heart attack, stroke, heart failure similar for newly medicated patients with HTN
Thursday, August 30, 2012

Resistance to Second-Line TB Drugs Is Common Globally
Nearly half resistant to at least one drug; 6.7 percent have extensively drug-resistant TB
Thursday, August 30, 2012

Lacunar Stroke Outcomes No Better With Dual Antiplatelets
Clopidogrel plus aspirin doesn't reduce recurrent stroke risk; increases major bleeding and death
Wednesday, August 29, 2012

Long-Term Thrombosis Rates Similar for Drug-Eluting Stents
Similar rates of stent thrombosis seen at three years for zotarolimus- and sirolimus-eluting stents
Wednesday, August 29, 2012

New Class of Drugs Shows Promise for Heart Failure
Angiotensin receptor neprilysin inhibitor lowers NT-proBNP levels more than valsartan
Tuesday, August 28, 2012

LABA Withdrawal Increases Asthma-Related Impairment
Study looks at patients with asthma controlled by long-acting a2-agonist plus an inhaled corticosteroid
Tuesday, August 28, 2012

For Patients With Prior MI, Vorapaxar Cuts Cardiac Events
Addition to standard antiplatelet therapy reduces thrombotic events, but increases bleeding
Monday, August 27, 2012

Prasugrel, Clopidogrel Similar for Acute Coronary Syndromes
Frequency of primary end point, bleeding risks similar for those not undergoing revascularization
Monday, August 27, 2012

Muscle-Related Statin Effects Seem to Correlate With Potency
Fluvastatin is apparent exception to potency prediction of muscle-related adverse effects
Friday, August 24, 2012

Prolonged Dexamethasone Cuts Delayed Nausea After Chemo
Adding dexamethasone to prochlorperazine on days two and three reduces delayed nausea after chemo
Wednesday, August 22, 2012

Prior Substance Abuse Linked to Opioid Abuse in Young Men
In young women, only prior marijuana use is associated with prescription opioid abuse
Tuesday, August 21, 2012

Study Shows 'SuperAgers' Have Thicker Cortex, No Atrophy
Thicker cerebral cortex than aged-matched controls; no atrophy versus middle-aged controls
Monday, August 20, 2012

Pegylated Interferon Affects Growth, BMI in Children
Effects on weight-for-age and BMI generally reversible with cessation of therapy
Thursday, August 16, 2012

FDA: Codeine May Be Fatal in Subset of Children
Some children genetically predisposed to convert codeine to dangerous levels of morphine
Wednesday, August 15, 2012

Risk of Liver Injury Up With Certain Fluoroquinolones
Moxifloxacin and levofloxacin approximately double risk of acute liver injury in older people
Monday, August 13, 2012

Aspirin Use Again Linked to Slightly Lower Cancer Mortality
But, relationship may not be as strong as in previously reported pooled-data analysis
Monday, August 13, 2012

Statin Benefits Outweigh Risk of Developing Diabetes
Diabetes risk only increased in those with one or more major risk factors
Friday, August 10, 2012

Reasons for Discontinuation Vary by Psoriasis Treatment
Frequency of each of 11 cited discontinuation reasons varies significantly by treatment
Friday, August 10, 2012

Similar Mortality With Different TNF-α Inhibitor Therapies in RA
No mortality differences between adalimumab, etanercept, and infliximab in rheumatoid arthritis
Thursday, August 09, 2012

Vaccine Transiently Modifies Autoimmunity in Diabetes
Tuberculosis vaccine increases insulin production in patients with long-term type 1 diabetes
Thursday, August 09, 2012

Oral Corticosteroids Deemed Ineffective for Rhinosinusitis
No significant difference in symptom relief between steroid group and placebo group
Tuesday, August 07, 2012

Topical Treatment Shows Potential for Infantile Eczema
Cream containing 15(R/S)-methyl-lipoxin A4 relieves severity of eczema, improves quality of life
Tuesday, August 07, 2012

Drug Helps Control Glucose in Congenital Hyperinsulinism
Glucagon-like peptide-1 receptor antagonist controls blood glucose and insulin levels
Tuesday, August 07, 2012

Photosensitizing Antihypertensive Meds Up Risk of Lip Cancer
Non-Hispanic whites treated long term with antihypertensives have increased odds of lip cancer
Tuesday, August 07, 2012

Sleep Duration Affects Hepatitis B Vaccine Response
Short sleep duration negatively impacts secondary antibody response and clinical protection
Monday, August 06, 2012

Exercise, Drugs Compared for Depression Tx in CHD Patients
Both exercise and sertraline effective; both tend to reduce heart rate variability
Thursday, August 02, 2012

Clinicians Can Unintentionally Prompt Nocebo Effect
Negative expectations, being informed about complications up likelihood of adverse effects
Thursday, August 02, 2012

Taxane-Induced Neuropathy Not Tied to Breast Cancer Outcome
In operable breast cancer, taxane-induced neuropathy not linked to survival, recurrence
Thursday, August 02, 2012

Caffeine Has Positive Effect on Motor Symptoms in Parkinson's
But limited effect on excessive daytime sleepiness
Wednesday, August 01, 2012

Higher Rates of Pertussis With Acellular Pertussis Vaccine
Children who receive mixed dose of DTaP and DTwP have higher rate if their first dose was DTaP
Tuesday, July 31, 2012

Levels of Etonogestrel Lower in Obese Women After Implant
Lower drug levels seen in obese women who receive a contraceptive implant
Tuesday, July 31, 2012

Donepezil Found Helpful in Dementia With Lewy Bodies
Improvement seen in cognitive, behavioral, global function when treated for 12 weeks at 5, 10 mg/day
Tuesday, July 31, 2012

'Bath Salts' Demonstrate High Potential for Abuse
Mice study shows mephedrone stimulates brain reward centers in similar manner to cocaine
Friday, July 27, 2012

Low-Dose Duloxetine Deemed Safe for Urinary Incontinence
Low incidence of adverse events in study of more than 12,000 women; no suicide attempts reported
Friday, July 27, 2012

Rituximab Useful in Idiopathic Membranous Nephropathy
Two-thirds of patients achieve remission and improved or stabilized renal function
Friday, July 27, 2012

Excess Maternal Iodine Linked to Congenital Hypothyroidism
Findings based on case studies of three infants and their mothers' nutritional supplement history
Thursday, July 26, 2012

Clopidogrel Response Remains Stable After Acute MI
For acute MI patients treated with PCI, response to clopidogrel therapy stable up to six months
Thursday, July 26, 2012

Selenium, Vitamins C, E May Lower Pancreatic Cancer Risk
Food diary data suggest higher antioxidant intake may cut pancreatic cancer risk by two-thirds
Thursday, July 26, 2012

Immunosuppressant Switch Cuts Skin Cancer Post-Transplant
Longer survival for kidney-transplant patients switched to sirolimus from calcineurin inhibitors
Wednesday, July 25, 2012

Vitamin E Intake Inversely Linked to Liver Cancer Risk
Vitamin E from diet or supplements may reduce the risk of developing liver cancer
Wednesday, July 25, 2012

Hair Loss Drug Shows Long-Term Sexual Side Effects
In most patients, finasteride-associated sexual dysfunction persists, even after drug discontinuation
Monday, July 23, 2012

HIV Drug-Resistance Up in Resource-Limited Settings
Increase in prevalence since antiretroviral rollout in regions of sub-Saharan African
Monday, July 23, 2012

Heart Medication Converts Cancer Cells Into Vaccine
Cardiac glycosides induce immunogenic cell death in cancer cells
Friday, July 20, 2012

Peri-Op Antidepressant Use Safe for Face-Lift Surgery
Serotonin reuptake inhibitor use in perioperative period safe; does not adversely affect outcome
Friday, July 20, 2012

Effect of Phosphate Binders in Chronic Kidney Disease Unclear
Linked to lower urinary, serum phosphorus, but promote progression of vascular calcification
Friday, July 20, 2012

Animal Study: Long-Term Ritalin Doesn't Impact Growth
Chronic methylphenidate treatment has no significant effect on growth measures, dopamine system
Friday, July 20, 2012

BMI Affects Aromatase Inhibitor-Linked Estrogen Suppression
Levels of estrogen up with letrozole, anastrozole for postmenopausal women with higher BMI
Friday, July 20, 2012

Poorer Patient Experience at Safety-Net Hospitals
Worse performance on nearly every measure of patient experience; discrepancy persisted over time
Thursday, July 19, 2012

~12,000 Preventable Deaths in English Hospitals Annually
Main causes are poor clinical monitoring, diagnostic errors, and inadequate drug/fluid management
Thursday, July 19, 2012

Social Network Analysis IDs Informal Physician Networks
Geographic variation in network characteristics; similar physician, patient features within networks
Tuesday, July 17, 2012

Aspirin Still First-Line Therapy for Unstable Angina/NSTEMI
Options for aspirin-intolerant include prasugrel (PCI-treated patients), ticagrelor, or clopidogrel
Monday, July 16, 2012

Nebivolol Better Preserves Exercise Performance at Altitude
Under acute exposure to high altitude hypobaric hypoxia, nebivolol better than carvedilol
Friday, July 13, 2012

Vitamin D Deficiency Linked to Poorer Lung Function in Children
Vitamin D levels should be monitored in children with asthma treated with inhaled corticosteroids
Friday, July 13, 2012

Chemo Combo Promising for Pancreatic Neuroendocrine Tumors
Greater benefit with temozolomide, bevacizumab for patients with pancreatic versus carcinoid NETs
Friday, July 13, 2012

Abuse-Deterrent OxyContin Produces Unexpected Outcome
OxyContin abuse down, but increase noted in use of alternative opioid medications and heroin
Thursday, July 12, 2012

Drug Reduces Graft-Versus-Host After Stem Cell Transplant
Chemokine receptor CCR5 antagonist maraviroc inhibits lymphocyte chemotaxis
Thursday, July 12, 2012

HIV Preexposure Prophylaxis With Antiretrovirals Explored
Value of prophylactic combination tenofovir-emtricitabine varies in three studies
Wednesday, July 11, 2012

Supplement Mixture Improves Memory in Mild Alzheimer's
Improvement seen both on cognitive tests and functional connectivity on EEG
Wednesday, July 11, 2012

Flu Shot in Pregnancy Not Tied to Adverse Fetal Outcomes
H1N1 flu vaccination linked to small but significantly increased risk of Guillain-Barré
Tuesday, July 10, 2012

Study Supports Chemo After Periampullary Cancer Surgery
Benefit only seen after adjusting for prognostic variables, not in primary analysis
Tuesday, July 10, 2012

Top Medical Organizations Support Hormone Replacement
HRT deemed safe and acceptable treatment for menopausal symptoms
Monday, July 09, 2012

Evidence of Herd Immunity After Introduction of HPV Vaccine
Significant drop in vaccine-type HPV in vaccinated, unvaccinated women
Monday, July 09, 2012

Unsuccessful Fertility Drug Use Lowers Breast Cancer Risk
Protective association disappears among women who successfully conceive on fertility drugs
Monday, July 09, 2012

Gestational Diabetes Risk Up With Antipsychotic Use
Risk of similar magnitude but not significant for those taking olanzapine and/or clozapine
Friday, July 06, 2012

Medicare Part D Gap Lowers Maintenance Antidepressant Use
Elderly with generic coverage reduce just their use of brand-name antidepressants
Friday, July 06, 2012

Obesity Is a Risk Factor for Poor Remission Rates in RA
Study looks at patients with long-standing rheumatoid arthritis treated with TNFα therapies
Friday, July 06, 2012

Early Intensive Diabetes Therapy Preserves β-Cell Function
β-cell function preserved for 3.5 years with insulin plus metformin or triple oral therapy
Friday, July 06, 2012

Dose-Escalated Cetuximab Tolerated in Colorectal Cancer
Possible improved response and disease control rates in irinotecan-refractory metastatic CRC
Thursday, July 05, 2012

Eltrombopag Linked to Clinical Response in Aplastic Anemia
Clinically significant multilineage response in some patients with severe refractory aplastic anemia
Thursday, July 05, 2012

High-Dose Vitamin D 'Somewhat Favorable' in Fracture Prevention
Benefits for elderly women consistent regardless of baseline levels, age, calcium intake
Thursday, July 05, 2012

Limited Evidence Links Pioglitazone to Bladder Cancer
Thiazolidinediones, specifically pioglitazone, may increase bladder cancer risk in type 2 diabetes
Tuesday, July 03, 2012

First Over-the-Counter HIV Test Approved
Results can be obtained within 40 minutes
Tuesday, July 03, 2012

Rheumatoid Arthritis Drug Not Linked to Specific Birth Defects
But authors advise use of contraception and avoidance of pregnancy while taking leflunomide
Tuesday, July 03, 2012

Hep B Screening Urged Before TNF-Alpha Inhibitor Therapy
Early, preemptive therapy can minimize hepatitis B reactivation; more reactivation with infliximab
Friday, June 29, 2012

Myrbetriq Approved for Overactive Bladder
Some 33 million Americans have the condition
Friday, June 29, 2012

Nelarabine Plus Chemo Viable in Children With T-Cell ALL
Nelarabine well tolerated; encouraging for pediatric patients with slow early response in T-cell ALL
Friday, June 29, 2012

Aspirin Use Linked to Reduced Risk of Barrett's Esophagus
Current aspirin users have a 44 percent lower risk of being diagnosed with Barrett's esophagus
Thursday, June 28, 2012

Supreme Court Upholds Health Care Reform Law
'Individual-mandate' insurance requirement deemed constitutional
Thursday, June 28, 2012

Omega-3 Supplements Reduce Inflammation in Overweight
Low- and high-dose omega-3 polyunsaturated fatty acids beneficial for healthy sedentary adults
Thursday, June 28, 2012

Linagliptin Noninferior to Glimepiride in Type 2 Diabetes
Significantly fewer patients have hypoglycemia, cardiovascular events with use of linagliptin
Thursday, June 28, 2012

FDA Clears First Weight-Loss Pill in 13 Years
Belviq designed to make people feel full sooner
Thursday, June 28, 2012

Duplicate Payments by Federal Government Increasing
Dually enrolled patients in the VA and Medicare account for substantial, duplicate costs
Wednesday, June 27, 2012

Early Start to ADHD Meds Lowers Risk of Academic Decline
Early initiation of stimulants linked to reduced academic decline in math, particularly for girls
Monday, June 25, 2012

Early Vaccinations Not Linked to Celiac Disease in Sweden
Changes in vaccinations don't account for epidemic; BCG vaccine linked to reduced risk
Monday, June 25, 2012

AHA: Vorapaxar Reduces Limb Ischemia in PAD
Does not reduce risk of cardiovascular death, myocardial infarction, stroke; ups bleeding risk
Friday, June 22, 2012

AHA: Concentrates Promising for Reversal of Apixaban
In vitro testing of three clotting agents demonstrates ability to reverse some effects of apixaban
Thursday, June 21, 2012

Genetic Contribution Detected in Responses to Opioids
Twin study shows significant inherited component for nausea, depressed breathing, drug liking
Thursday, June 21, 2012

Multi-Drug Regimens Cut HIV Transmission Versus Zidovudine
Second study shows virologic failure higher in infants treated with nevirapine versus lopinavir
Wednesday, June 20, 2012

Research Suggests Flavocoxid Causes Acute Liver Injury
Injury seen as mixed hepatocellular-cholestatic hepatitis beginning within one to three months of use
Tuesday, June 19, 2012

Belimumab Deemed Safe for Long-Term Lupus Treatment
In study, incidence rates of adverse events remained stable or declined over four-year follow-up
Tuesday, June 19, 2012

A Shift in Pediatric Drug Utilization Seen 2002 to 2010
Increased utilization of ADHD medication; decreased antibiotic, allergy medication use
Monday, June 18, 2012

Genetic Variants Predict Outcomes After t-PA Treatment
Two single nucleotide polymorphisms correlate with hemorrhagic transformation, in-hospital death
Monday, June 18, 2012

Review: Vitamin D Plus Calcium Linked to Mortality Reduction
Effect not seen for vitamin D alone in either individual patient data or trial level meta-analyses
Friday, June 15, 2012

Menhibrix Approved to Prevent Bacterial Infections in Infants
Approval covers infants and toddlers ages 6 weeks through 18 months
Friday, June 15, 2012

Testosterone Therapy Does Not Up Prostate Cancer Incidence
One case of cancer diagnosed per 212 years of testosterone replacement therapy
Friday, June 15, 2012

Mental Health Disorders Up Long-Term Opioid Use in Youth
About two-fold risk of long-term opioid use for youth with preexisting mental health disorders
Thursday, June 14, 2012

Statins Exhibit Adverse Effect on Energy, Exertional Fatigue
Randomized trial shows unfavorable effect of statins on energy and fatigue, particularly for women
Thursday, June 14, 2012

Cognitive Benefit of Omega-3s in Older Adults Questioned
Review finds that direct evidence on the effect of omega-3 PUFA on incident dementia is lacking
Thursday, June 14, 2012

Ethinyl Estradiol Dose, Progestin Type Affect the Pill's Stroke Risk
However, risk of thrombotic stroke and myocardial infarction is generally low for oral contraceptives
Wednesday, June 13, 2012

Life-Long Rx Not Always Needed for Juvenile Myoclonic Epilepsy
JME is heterogeneous syndrome; life-long treatment not always needed to maintain seizure freedom
Wednesday, June 13, 2012

Changes in Tumor Size by RECIST Correlate With Survival
Reflect linear continuum without clear boundary values or cutoffs to define response
Wednesday, June 13, 2012

Cannabinoid Formulation Benefits Opioid-Refractory Pain
Nabiximols offers pain relief for patients with advanced cancer, especially at low-dose
Wednesday, June 13, 2012

In Vitro Fertilization Linked to Multiple Sclerosis Relapse
Risk higher with failed IVF or with use of gonadotrophin releasing hormone agonists
Wednesday, June 13, 2012

Curbing Antibiotic Prophylaxis Doesn't Up Endocarditis Risk
No increase in infective endocarditis in high-heart risk dental patients since 2007 AHA guidelines
Wednesday, June 13, 2012

Task Force Questions Use of Vitamin D, Calcium Supplements
Government advisory panel finds insufficient evidence to support protective role of supplements
Tuesday, June 12, 2012

ADA: Salsalate Doesn't Up Endothelial Function in T2DM
No change in flow-mediated, endothelium-dependent dilation; lower Hb1Ac, inflammatory markers
Tuesday, June 12, 2012

ADA: Impact of Insulin Glargine on Cardio Outcomes Negligible
Modest weight gain and increase in severe hypoglycemia when compared to standard care
Tuesday, June 12, 2012

ADA: Hypo-Hyperglycemia Minimizer System Feasible
Two studies show system is able to predict changes in glucose and manipulate insulin delivery
Monday, June 11, 2012

Thiazolidinedione Use Linked to Diabetic Macular Edema
Increased risk seen at one- and 10-year follow-up; no difference for pioglitazone, rosiglitazone
Monday, June 11, 2012

ADA: Omega-3 Fatty Acids Don't Cut Cardiovascular Death
No significant effect seen for patients with dysglycemia and other cardiovascular risk factors
Monday, June 11, 2012

Marker Helps Predict Thrombotic Risk of Hormonal Contraceptives
For women taking hormonal contraceptives, sex hormone-binding globulin levels help estimate risk
Friday, June 08, 2012

Higher Risk of VTE in CKD Surgical Patients on Enoxaparin
Compared to desirudin, VTE risk up for enoxaparin-treated CKD stage 3B patients after THR
Friday, June 08, 2012

Multidrug-Resistance Seen in ~10 Percent of TB Cases in China
And, a new drug shows significantly improved sputum-culture conversion at two months
Wednesday, June 06, 2012

Anti-HTN Drugs Have Distinct Effect on Central, Brachial SBP
Central to brachial amplification lowered by beta blockers, thiazide diuretics, and omapatrilat
Wednesday, June 06, 2012

Many Adults May Accidentally Overdose on Acetaminophen
Limited literacy, heavy use of acetaminophen-containing products independently linked to risk
Wednesday, June 06, 2012

Aspirin Ups Risk of Bleeding in All But Diabetes Patients
Patients with diabetes have increased risk of major bleeding, independent of aspirin use
Tuesday, June 05, 2012

Head Lice Beginning to Show Permethrin Resistance
Approximately 14 percent of head lice in Parisian children resistant to the insecticide permethrin
Tuesday, June 05, 2012

In A-Fib, Rhythm Control Reduces Mortality in Long Term
Little difference within four years of initiation of rhythm, rate control; rhythm superior in long term
Tuesday, June 05, 2012

Many Patients Keep Using PPIs After Negative GERD Test
Nearly half of patients keep using proton pump inhibitors; most don't recall being told to stop
Tuesday, June 05, 2012

ASCO: Continuing Avastin With 2nd-Line Chemo Ups Survival
Findings in patients with metastatic colorectal cancer treated with first-line chemo plus Avastin
Tuesday, June 05, 2012

ASCO: Avastin Ups Survival in Platinum-Resistant Ovarian CA
Addition of bevacizumab to chemotherapy improves progression-free survival
Monday, June 04, 2012

Gene Variants Impact Smokers' Response to Cessation Therapy
High-risk haplotypes predict later age of smoking cessation; interact with treatment to affect success
Friday, June 01, 2012

Pioglitazone Use Ups Bladder Cancer Risk in Type 2 Diabetes
Highest risk for those with more than 24 months of exposure, cumulative dose of >28,000 mg
Friday, June 01, 2012

Cardiovascular Risk Counseling Improves Statin Adherence
Nurse-led counseling reduces anxiety; improved lipid profile seen for primary prevention patients
Thursday, May 31, 2012

Adjunct Zinc Cuts Antibiotic Treatment Failure for Infants
Addition of zinc to antibiotics benefits infants aged 7 to 120 days with probable serious bacterial infection
Thursday, May 31, 2012

Oral, Injected Methotrexate Have Similar Efficacy in JIA
Injected methotrexate could be discontinued in favor of oral administration in juvenile idiopathic arthritis
Wednesday, May 30, 2012

Online Adderall May Contain Wrong Active Ingredients
FDA warns that counterfeit drug may be ineffective and potentially harmful
Wednesday, May 30, 2012

Acne Medication Isotretinoin Increases Risk of Eye Disorders
Lack of lubrication, or dry eyes, may contribute to adverse ocular effects
Wednesday, May 30, 2012

NSAID Use Linked to Reduced Risk of Skin Cancer
Lower risk of squamous cell carcinoma, malignant melanoma; notably in long-term, high-intensity use
Tuesday, May 29, 2012

Evidence Updated for Impact of Menopausal Hormone Therapy
Updated review mainly based on evidence from 11 years of follow-up in Women's Health Initiative
Tuesday, May 29, 2012

PUFA Formula Supplementation Doesn't Up Infant Cognition
And, milk and soy formula fed infants have similar cognitive outcomes, slightly lower than breastfed
Tuesday, May 29, 2012

Upping Dietary Calcium Buys No Big Cardiovascular Benefit
Whereas calcium supplements linked to significant increase in risk of myocardial infarction
Friday, May 25, 2012

Common Therapies for Basal Cell Carcinoma Offer Similar Survival
Long-term tumor-free survival similar for imiquimod, photodynamic therapy
Friday, May 25, 2012

Magnesium Not Recommended After Subarachnoid Bleed
Randomized trial concurs with meta-analysis indicating no benefit for reduction of poor outcome
Friday, May 25, 2012

Low-Glucose Suspend Function in Insulin Pumps Deemed Safe
Findings based on overnight events with two-hour suspension with no adverse outcomes
Thursday, May 24, 2012

Vemurafenib, Dabrafenib Linked to Cutaneous Side Effects
Squamous cell carcinoma, warty dyskeratomas, verrucous keratoses, and other lesions can occur
Thursday, May 24, 2012

Brentuximab Vedotin Effective in Large-Cell Lymphoma
Complete remission for more than half with recurrent systemic anaplastic large-cell lymphoma
Thursday, May 24, 2012

DDW: Pancreatic CA Shot Added to Standard Therapy Ups Survival
In a related study, 4D-elastic light scattering fingerprinting probe detects pancreatic cancer
Thursday, May 24, 2012

Treatment With rt-PA Within Six Hours of Stroke Beneficial
Randomized trial, meta-analysis show benefit for wide range of patients with acute ischemic stroke
Wednesday, May 23, 2012

IUDs, Implants Most Effective for Preventing Pregnancy
Regardless of age, contraceptive failure rate higher among pill, patch, and ring users
Wednesday, May 23, 2012

Aspirin Effective in Preventing Thromboembolism Recurrence
For patients with unprovoked VTE, aspirin presents no apparent increase in risk of major bleeding
Wednesday, May 23, 2012

ATS: Anticholinergics May Up Arrhythmia Risk in Children
Finding raises concern regarding interest in the use of anticholinergics in asthma patients
Wednesday, May 23, 2012

Regorafenib Active in Metastatic GI Stromal Tumors
Significant activity for patients with advanced GIST after failure of imatinib and sunitinib
Wednesday, May 23, 2012

DDW: Estrogens Tied to Risk of Inflammatory Bowel Diseases
Studies show HRT increases risk of ulcerative colitis, oral contraceptives up risk of Crohn's
Tuesday, May 22, 2012

Chemoradiotherapy Improves Survival for Elderly With NSCLC
Addition of carboplatin to radiotherapy prolongs overall survival in locally advanced disease
Tuesday, May 22, 2012

Post-Stroke Inpatient Statins Improve Discharge Outcomes
After ischemic stroke, inpatient statin use increases likelihood of discharge to home or institution
Tuesday, May 22, 2012

Dabrafenib Safe, Active Against Some Metastatic Melanomas
Drug shows antitumor activity against Val600-mutant BRAF tumors at phase 2 dose of 150 mg
Monday, May 21, 2012

Sunscreen Ingredient May Be Linked to Risk of Endometriosis
Higher urinary concentration of benzophenone-type derivatives ups odds of endometriosis diagnosis
Friday, May 18, 2012

Gene Expression Profile Testing Increasing in Breast Cancer
Linked with decrease in chemotherapy in women with hormone receptor-positive breast cancer
Thursday, May 17, 2012

IMFAR: Oxytocin Nasal Spray Promising in Youth With Autism
Functional MRIs show increased activity in brain regions known to process social information
Thursday, May 17, 2012

Generic Versions of Plavix Approved
Dispensed with Medication Guide that provides important instructions on use, drug safety
Thursday, May 17, 2012

ASCO: For Chemo's Nausea, Olanzapine Beats Metoclopramide
Patients with breakthrough chemo-induced nausea and vomiting benefit from olanzapine
Thursday, May 17, 2012

ASCO: Abiraterone Tolerated in High-Risk Prostate Cancer
Good pathological complete/near complete response with abiraterone + leuprolide
Thursday, May 17, 2012

Statins Benefit Those at Low Risk for Vascular Events
Review shows benefit even for those with five-year risk of major vascular events of <10 percent
Thursday, May 17, 2012

Leukoencephalopathy Risk Factors ID'd for MS Drug
Risk with natalizumab treatment linked to JC virus status, immunosuppressants, treatment duration
Wednesday, May 16, 2012

Azithromycin Tied to Increased Risk of Cardiovascular Mortality
Increased risk of all-cause, cardio mortality; especially in those at risk for cardiovascular disease
Wednesday, May 16, 2012

Pazopanib Active in Metastatic Soft-Tissue Sarcoma
Progression-free survival up in metastatic non-adipocyte soft-tissue sarcoma, after chemo
Wednesday, May 16, 2012

U.S. Lifetime Prevalence of Sleep Walking ~30 Percent
More frequent episodes linked to obstructive sleep apnea; alcohol abuse; use of sleeping pills, SSRIs
Tuesday, May 15, 2012

Small Benefit of Inhaled Corticosteroids for Sinusitis
Review shows benefits may be greater at increased doses and with courses of several weeks duration
Tuesday, May 15, 2012

ECO: New Weight Loss Drug Effective in Advanced Obesity
Phentermine/topiramate linked to elevated weight loss; dose-response association noted
Monday, May 14, 2012

AHA: Clot-Busting Drug OK for Stroke Patients on Warfarin
No increased intracranial hemorrhage risk for acute ischemic stroke patients using warfarin
Monday, May 14, 2012

Post-SES Implantation, Statins Prevent Late Revascularization
Statins cut risk of late target lesion revascularization after sirolimus-eluting stent implant
Friday, May 11, 2012

AHA: Telemonitoring Improves Blood Pressure Control
Telemonitoring with pharmacist-directed therapy adjustments improves adherence, lowers BP
Friday, May 11, 2012

Blood Clot Risk Elevated in Patch and Vaginal Ring Users
Risk of venous thrombosis higher in non-oral contraceptives compared to oral contraceptives
Friday, May 11, 2012

HRS: Statins Reduce the Risk of A-Fib in Elderly With HTN
Statins are particularly effective for patients with CHADS2 score of ≥2, other comorbidities
Friday, May 11, 2012

Rituximab Little Use in Resistant Idiopathic Nephrotic Syndrome
Drug does not reduce proteinuria in combination with prednisone, calcineurin inhibitors
Friday, May 11, 2012

Nonmedical Prescription Pain Medication Use Peaks at Age 16
Smaller peaks in pain med use to get high or for nonmedical purposes seen at 12-14, 19-21 years
Thursday, May 10, 2012

ECO: Normalizing Testosterone in Men Linked to Weight Loss
Testosterone shots linked to reduced BMI, waist circumference, BP, improved metabolic profile
Thursday, May 10, 2012

Avastin and Lucentis Equally Improve Visual Acuity in AMD
Taken monthly, the drugs have similar effects on age-related macular degeneration over two years
Wednesday, May 09, 2012

Epilepsy Treatment Response Patterns Usually Constant
Most patients with epilepsy have constant treatment course which can be predicted early
Wednesday, May 09, 2012

High Infection Rates Seen in Juvenile Idiopathic Arthritis
Oral glucocoticoids, but not methotrexate or TNF inhibitor use linked to increased infection
Wednesday, May 09, 2012

Pediatric Content in Drug Labeling Has Increased
But only 46 percent of drugs listed in the Physicians' Desk Reference have pediatric information
Wednesday, May 09, 2012

Metformin May Have Dual Effect in Breast Cancer
Ki-67 affected differently based on insulin resistance, particularly in luminal B tumors
Wednesday, May 09, 2012

Probiotics Helpful in Reducing Antibiotic-Related Diarrhea
More research needed to determine which probiotics are effective for specific antibiotics
Tuesday, May 08, 2012

Tenofovir Disoproxil Fumarate Doesn't Impact Fetal Growth
Anti-HIV drug doesn't affect newborn size, but may delay growth during first year
Tuesday, May 08, 2012

Zinc May Shorten Duration of Common Cold in Adults
Symptoms reduced in adults, but not children; bad taste, nausea are common adverse effects
Monday, May 07, 2012

Modified Fluorene Compound Potently Disrupts Amyloid-β
Fluorene modified with pyrroline nitroxide has antioxidant properties, disrupts Aβ oligomers
Monday, May 07, 2012

Resistance Patterns of Urinary E. coli Isolates Changing
2000 to 2010 saw considerable increase in resistance to ciprofloxacin, TMP-SMX
Monday, May 07, 2012

Lupus Nephritis Screening and Management Guidelines Issued
Include methods for identifying disease, new therapies, and treatment of pregnant patients
Friday, May 04, 2012

Complementary Medicine Not Tied to Prostate Cancer Outcome
Complementary, alternative medicine widely used; no effect on treatment satisfaction, outcomes
Friday, May 04, 2012

Antipsychotic Maintenance Rx Aids Schizophrenia Patients
But benefits of antipsychotic maintenance therapy need to be weighed against risk of side effects
Thursday, May 03, 2012

CDC: Teen Birth Rate Decreasing in United States
Decrease from 1990 to 2006-2010 may reflect an increase in the proportion of abstinent females
Thursday, May 03, 2012

Erlotinib Plus Chemo Doesn't Improve Efficacy in NSCLC
Offers no benefit for never or light former smokers with advanced non-small-cell lung cancer
Wednesday, May 02, 2012

Chemo Combination Promising for Multiple Myeloma
Elotuzumab, lenalidomide, low-dose dexamethasone well tolerated in relapsed/refractory MM
Wednesday, May 02, 2012

Methodological Heterogeneity Seen in Clinical Trials
Trials registered with ClinicalTrials.gov from 2007 to 2010 mainly small, single-center
Tuesday, May 01, 2012

PAS: Maternal Opioid Use, Neonatal Withdrawal Rising
Increase in neonatal abstinence syndrome from 2000 to 2009 accompanied by increase in hospital costs
Monday, April 30, 2012

Electronic Reminders Up Meds Adherence in Short Term
Electronic reminders, especially SMS reminders, are effective in short term for chronic medications
Monday, April 30, 2012

Levaquin Approved to Treat or Prevent Plague
Deadly disease rare in the United States
Monday, April 30, 2012

PAS: Combined Treatment Ups Glycemic Control in Young
Rosiglitazone plus metformin beats metformin alone or lifestyle interventions in adolescents with T2DM
Monday, April 30, 2012

AAN: Migraine Prevalence Up in Celiac Disease, IBD Patients
U.S. study finds self-classified gluten-sensitive individuals have increased odds of migraines
Friday, April 27, 2012

Excessive Neutropenia for Weekly Everolimus + Docetaxel
Dose-limiting neutropenia, variable drug clearance for patients with metastatic breast cancer
Friday, April 27, 2012

Accelerated Aging Evident in Cocaine-Dependent Individuals
Age-related gray matter volume loss occurs at twice the normal rate
Thursday, April 26, 2012

Modulator of mGluR5 Improves Features of Autism in Mice
GRN-529 reduces repetitive behaviors and partially reverses lack of sociability
Thursday, April 26, 2012

AHA: Similar Stroke Risk on Stopping Rivaroxaban, Warfarin
Similar, high stroke risk for patients with a-fib who temporarily or permanently discontinue meds
Thursday, April 26, 2012

Hyperalgesia Similar With Drug Therapies for Heroin Addiction
Once stabilized in treatment, no difference in pain response for methadone or buprenorphine
Thursday, April 26, 2012

Botox Modestly Improves Chronic Headaches, Migraines
But is not associated with reduction in frequency of episodic migraine or tension-type headaches
Wednesday, April 25, 2012

Meds, Clinic Noncompliance Linked to Mortality in Diabetes
Medication, clinic appointment noncompliance ups mortality in insulin-treated type 2 diabetes
Tuesday, April 24, 2012

AAN: Recommendations for Migraine Prevention Issued
Frequency and severity of migraine attacks can be reduced using seizure drugs and beta-blockers
Monday, April 23, 2012

Angiotensin Receptor Blockers Reduce No-Reflow Post-PCI
For patients with acute MI, ARB pretreatment is significant predictor of reduced no-reflow
Monday, April 23, 2012

Efficacy of Serotonin Receptor Inhibitors in Autism Unclear
Meta-analysis finds evidence SRIs help repetitive behaviors; results may be due to publication bias
Monday, April 23, 2012

Shingles Vaccine Generally Well Tolerated in Older Adults
Small, but significant, increased risk of allergic reaction in days one to seven following vaccination
Monday, April 23, 2012

Metformin + Insulin Comparable to Insulin Alone in T2DM
More data needed to determine whether combined use of oral therapy and insulin adds benefit
Friday, April 20, 2012

Study Compares Effectiveness of Psoriasis Treatments
For patients with plaque psoriasis, treatment effectiveness may be lower than seen in trial settings
Friday, April 20, 2012

AAN: Drug Reduces Progression to Clinically Definite MS
Taking interferon β-1a soon after a clinical event for possible MS delays progression to clear diagnosis
Thursday, April 19, 2012

Chemoradiotherapy Combo Ups Bladder Cancer Control
Locoregional control of muscle-invasive bladder cancer improved without additional toxicity
Wednesday, April 18, 2012

Albendazole Cuts Enteric Parasite Prevalence in Refugees
Presumptive predeparture single-dose albendazole reduces intestinal nematodes in refugees
Wednesday, April 18, 2012

FDA: Clinicians Urged to Stop Using Certain Ultrasound Gel
Specific lots found to have been contaminated by bacteria; 16 patients known to be affected
Wednesday, April 18, 2012

AAN: Intestinal Gel Improves 'Off' Time in Parkinson's
Levodopa-carbidopa gel offers significant improvements versus immediate release tablets
Wednesday, April 18, 2012

New Treatment Offers Benefit for Hypoxic Laryngeal Tumors
Accelerated radiotherapy plus carbogen and nicotinamide improves regional, not local, control
Wednesday, April 18, 2012

Medicare Coverage Gap Leads to Drug Discontinuation
About 57 percent of Medicare Part D patients stop taking cardiovascular drugs in coverage gap
Wednesday, April 18, 2012

ICD-9 Codes Underestimate Statin-Linked Rhabdomyolysis
Use of validated cases instead of ICD-9 code results in higher relative risk for high-dose statins
Tuesday, April 17, 2012

Preexposure Chemoprophylaxis Cuts HIV Infection at a Cost
Targeted prophylaxis strategy most cost-effective in highest risk men who have sex with men
Tuesday, April 17, 2012

Evidence Lacking for Value of CKD Screening and Monitoring
Variable quality of evidence found for effect of chronic kidney disease treatment options
Tuesday, April 17, 2012

AAN: Drug Reduces Brain Lesions in Multiple Sclerosis
Investigational drug is well tolerated in patients with relapsing-remitting MS
Monday, April 16, 2012

Low Gastroprotective Drug Adherence Ups Upper GI Events
Increased risk of events in patients taking coxibs with low adherence to gastroprotective agents
Monday, April 16, 2012

Alcohol Use With Opioids Common Even Without Abuse Past
Concurrent use of CNS depressants can lead to respiratory depression or sedation
Monday, April 16, 2012

Metal Binding Important for Metformin Action
Mechanism of action may involve copper binding
Friday, April 13, 2012

Crizotinib Treatment Lowers Total Testosterone Levels
In men with non-small-cell lung cancer, crizotinib rapidly suppressed testosterone levels
Friday, April 13, 2012

Pegaptanib Reduces Foveal Thickness in Macular Edema
Concomitant improvement in visual acuity, macular sensitivity, color discrimination in diabetes
Friday, April 13, 2012

Sequencing Traditional Chinese Medicines Reveals Surprises
Ingredients include potentially toxic plants and traces of endangered animals
Friday, April 13, 2012

Role of Omega-3 in Secondary Prevention of CVD Questioned
Meta-analysis finds inconclusive evidence of benefit in secondary prevention of cardiovascular events
Thursday, April 12, 2012

Bevacizumab Offers Lasting Improvement in Macular Edema
Best-corrected visual acuity significantly improved at two years for patients with diabetes-related CSME
Thursday, April 12, 2012

Antidepressants Don't Worsen Parkinson's Symptoms
Paroxetine and venlafaxine XR effectively treat depression in Parkinson's patients
Wednesday, April 11, 2012

Death Risk Similar With High-Dose Losartan, Candesartan
For patients with heart failure, low- or medium-dose losartan linked to increased mortality
Tuesday, April 10, 2012

Injectable Contraceptive Linked to Elevated Breast Cancer Risk
Recent use of depo-medroxyprogesterone acetate for 12 months or longer may double risk
Tuesday, April 10, 2012

Alternative Medicine Doesn't Affect Asthma Care in Children
Pediatric asthma patients have high med adherence regardless of alternative medicine
Tuesday, April 10, 2012

Report Highlights Child Deaths From Post-Surgery Codeine Use
Genetic variants produce ultra-rapid metabolizer phenotypes tied to respiratory arrest
Monday, April 09, 2012

Statins Moderate Effect of Metformin on Prostate Cancer
Taking both metformin and statins significantly reduces the incidence of prostate cancer
Monday, April 09, 2012

Treating Hepatic Encephalopathy Reduces Costs Due to MVAs
Diagnosis and lactulose treatment linked to reduced motor vehicle accident-related costs
Friday, April 06, 2012

Immunotherapy Tied to Lower Alzheimer's CSF Biomarkers
Anti-β-amyloid monoclonal antibody, bapineuzumab, linked to decreases in T-tau, P-tau
Friday, April 06, 2012

Antibiotics Safe and Effective to Treat Appendicitis
Meta-analysis indicates initial treatment with antibiotics may reduce the need for appendectomy
Friday, April 06, 2012

Full Weight-Based Chemo Doses Recommended for Obese
ASCO committee finds no evidence of increased short- or long-term toxicity in obese patients
Thursday, April 05, 2012

Prenatal Antipsychotics Impact Infant Neuromotor Function
Exposure to antipsychotics adversely affects neuromotor function in 6-month-old infants
Thursday, April 05, 2012

New Combination Malaria Treatment Equally Effective
Pyronaridine-artesunate as effective as mefloquine plus artesunate for uncomplicated malaria
Thursday, April 05, 2012

New Guidelines Issued for Rheumatoid Arthritis Treatment
Update of 2008 guidelines addresses screening for TB, immunization, treatment in high-risk patients
Thursday, April 05, 2012

Medical Malpractice Claims Incur Substantial Defense Costs
Costs higher for claims resulting in indemnity payments; significant variation by specialty
Wednesday, April 04, 2012

Reduced-Intensity Chemo Effective in Hodgkin's
Six cycles of BEACOPPescalated more effective and less toxic than eight cycles
Wednesday, April 04, 2012

Alcohol, Drug Use Prevalent Among U.S. Adolescents
Onset of alcohol abuse seen at median age of 14 years; drug abuse onset at 14 or 15 years
Wednesday, April 04, 2012

Cetuximab With Chemo Doesn't Improve Colon Cancer Outcome
For stage III resected colon cancer, disease-free survival no better than with mFOLFOX6 alone
Tuesday, April 03, 2012

Fluoroquinolone Use Linked to Retinal Detachment
Current use of oral antibiotic linked to increased detachment risk, but absolute risk is small
Tuesday, April 03, 2012

Neupro Approved for Advanced Parkinson's and Restless Leg Syndrome
Thought to stimulate brain receptors governing movement
Tuesday, April 03, 2012

Serious Eye Disease Linked to Bisphosphonate Use
First-time oral bisphosphonate users at higher risk of developing uveitis and scleritis
Monday, April 02, 2012

AACR: Metformin May Benefit Prostate Cancer Patients
Metformin may improve prostate-specific antigen levels and slow cancer growth
Monday, April 02, 2012

AACR: Study Links Long-Term Estrogen Use to Breast Cancer
Risk increased with estrogen, estrogen + progesterone; no increase in fatal breast cancer
Monday, April 02, 2012

Similar Rates of Depression After Stroke and TIA
High frequency of newly identified depression; many with depression not appropriately treated
Friday, March 30, 2012

Statin Discontinuation Linked to Mortality in RA Patients
Increases risk of cardiovascular, all-cause death; suggests importance of treatment compliance
Thursday, March 29, 2012

Prophylaxis With Apixaban Feasible for Cancer Patients
Phase II study shows Factor Xa inhibitor safe and tolerated in chemotherapy-treated patients
Thursday, March 29, 2012

Cost Sharing Reduces Use of Asthma Medication
Results in increased frequency of asthma-related hospitalizations in children age 5 or older
Tuesday, March 27, 2012

Diagnosis of ADHD Has Risen 66 Percent Over Last Decade
More than 10 million children and adolescents diagnosed with ADHD in 2010 in the United States
Tuesday, March 27, 2012

Confusion About Emergency Contraception Access Common
Most misinformation related to what age women and teens can take it without a prescription
Monday, March 26, 2012

Health Care Team Members Key for Antimicrobial Stewardship
Epidemiologists, preventionists help stop infections caused by multidrug-resistant organisms
Thursday, March 22, 2012

Tenecteplase Superior to Alteplase for Stroke Treatment
Preliminary data show improved reperfusion, significant clinical improvements in select patients
Wednesday, March 21, 2012

Regular Aspirin Use Can Lower Cancer Risk, Studies Confirm
Lowers risk of esophageal, gastric, biliary, and breast cancer; reduces distant metastases
Wednesday, March 21, 2012

Dexmedetomidine Non Inferior for Maintaining Sedation
Dexmedetomidine not inferior to midazolam or propofol during prolonged mechanical ventilation
Wednesday, March 21, 2012

Vitamin E Does Not Reduce Risk of Heart Failure in Women
Long-term treatment not linked to heart failure risk in initially healthy women
Tuesday, March 20, 2012

Nurse-Initiated Steroids Improve Pediatric Asthma Care
In pediatric ER, time to clinical improvement and discharge shortened for children with asthma
Tuesday, March 20, 2012

Synthetic Cannabinoid Toxicity Among Teenagers on the Rise
Case reports describe signs, symptoms, and treatment in teen patients
Monday, March 19, 2012

Poorer Health Literacy Linked to Increased Mortality
About one-third of older adults in England have medium or low functional health literacy
Friday, March 16, 2012

Analgesic Use After Surgery Linked to Long-Term Use
Prescription of opioids, NSAIDs within seven days of low-risk surgery increases risk of long-term use
Thursday, March 15, 2012

Higher Spending by Hospitals Improves Outcomes
Lower mortality, readmission for acute patients admitted to hospital in highest tercile of spending
Tuesday, March 13, 2012

U.S. Mortality Rates Dropped 60 Percent From 1935 to 2010
For every year, heart disease, cancer, and stroke are among the five leading causes of death
Tuesday, March 13, 2012

Flu Vaccine Up Among Medical Staff When They Believe It Works
Hospital health care workers more likely to get vaccinated when committed to preventing flu
Friday, March 09, 2012

Buprenorphine Maintenance Therapy Not Recommended
Abstinence-based therapy recommended instead for opioid-addicted health care professionals
Thursday, March 08, 2012

Cognitive Benefits With Continued Donepezil in Alzheimer's
For moderate or severe disease, benefits seen with continued treatment, alone or with memantine
Wednesday, March 07, 2012

Financial Burden of Medical Care Affects One in Three
More than one in five poor or near-poor adults younger than 65 have bills they are unable to pay
Wednesday, March 07, 2012

Veterans With Mental Health Issues Receive More Opioids
Risks of opioid use and adverse clinical outcomes especially high in veterans with PTSD
Tuesday, March 06, 2012

Dutasteride Doesn't Alter Anabolic Effects of Testosterone
No significant difference found for men taking testosterone with dutasteride or with placebo
Tuesday, March 06, 2012

AAAAI: 2000 to 2009 Saw Rise in Angioedema Hospitalizations
Increase especially high for African-Americans; often due to adverse effects of ACE inhibitors
Tuesday, March 06, 2012

AAAAI: Corticosteroid Response in Asthma Impacted by BMI
For children, high BMI linked to decreased CS response, increased requirement for inhaled CS
Monday, March 05, 2012

Youngest in Class More Likely to Be Diagnosed With ADHD
Boys and girls born in December more likely to be diagnosed and treated for ADHD
Monday, March 05, 2012

Prenatal Ecstasy Use May Harm Infant Development
Use of ecstasy during pregnancy impacts fetal and early infant development
Monday, March 05, 2012

Drug Relieves Opioid-Induced Constipation in Critically Ill
Methylnaltrexone improves bowel function compared with conventional rescue laxatives
Monday, March 05, 2012

Parent Training, Meds Combo Improves Behavior in PDD
Modest extra benefit for children with pervasive developmental disorders, behavioral problems
Friday, March 02, 2012

Phone Counseling Doesn't Up Osteoporosis Meds Adherence
No improvement in osteoporosis medication adherence in elderly, predominantly female cohort
Thursday, March 01, 2012

Vandetanib Doesn't Up Survival in Non-Small-Cell Lung Cancer
For patients with advanced NSCLC, no survival benefit; increased frequency of adverse events
Thursday, March 01, 2012

Nicotine Patches Don't Help Pregnant Women Stop Smoking
User compliance is low and rates of smoking abstinence do not increase with the patch
Wednesday, February 29, 2012

Statin Users Less Likely to Suffer From Depression
Patients with coronary heart disease who use statins have a lower risk of depression
Wednesday, February 29, 2012

Despite Benefits of Selenium, Supplements May Be Harmful
Supplements not indicated for those with selenium concentration of 122 µg/L or higher
Wednesday, February 29, 2012

Sleeping Pill Use Linked to Greater Mortality Risk
Greater than three-fold higher risk even for fewer than 18 pills a year
Tuesday, February 28, 2012

FDA Approves Label Changes for Statins
Cognitive and blood sugar side effects added; recommendation of routine liver monitoring dropped
Tuesday, February 28, 2012

Heartburn Controlled With Step Down to Once Daily Therapy
Once-daily dexlansoprazole improves quality of life for gastrosophageal reflux disease patients
Monday, February 27, 2012

AAP Recommends HPV Vaccine for Boys, Too
Follows guidance provided by the U.S. Centers for Disease Control and Prevention
Monday, February 27, 2012

ASD Meds More Commonly Used by Teens With Comorbid ADHD
Teenagers with autism more likely to use psychotropic medication if they also have ADHD
Friday, February 24, 2012

UVB Preferred for Treatment of Moderate to Severe Psoriasis
Dermatologist treatment preferences vary by geographical region
Friday, February 24, 2012

Variable Mortality Risk for Antipsychotic Use in Elderly
Effect strongest soon after start of treatment; dose-response relationship for most drugs
Friday, February 24, 2012

Model Predicts Death Due to Acetaminophen Overdose
Mathematical model estimates overdose amount, time elapsed; predicts outcome in acute liver failure
Friday, February 24, 2012

Aspirin and Clopidogrel Improve Claudication Distance
Similar improvement in patients with intermittent claudication due to peripheral arterial disease
Thursday, February 23, 2012

Bisphosphonate Use Linked to Reduced Colorectal Cancer Risk
On analysis of specific bisphosphonates, effect significant only for risedronic acid
Thursday, February 23, 2012

Pharmacist-Led Intervention Reduces Medical Errors
Intervention includes feedback, educational outreach, dedicated support and is cost-effective
Tuesday, February 21, 2012

Nicotine Replacement Therapy Linked With Infantile Colic
Women who smoke, use NRT, or both have increased risk of infantile colic in their offspring
Monday, February 20, 2012

Donepezil Improves Symptoms in Dementia With Lewy Bodies
Significant cognitive, behavioral, and global improvements seen at 5 or 10 mg/day donepezil
Friday, February 17, 2012

Smoking Cessation Drug May Also Reduce Drinking
Varenicline increases alcohol's aversive effects, including dysphoria and nausea
Friday, February 17, 2012

Overdose Prevention Programs Using Opioid Antagonist
Naloxone use, however, not sufficient to address high overdose death rates
Thursday, February 16, 2012

Smoking Bans Lead to Less, Not More, Smoking at Home
In countries with smoke-free legislation, rate of home smoking has decreased, not increased
Thursday, February 16, 2012

Intramuscular Midazolam As Safe As Intravenous Lorazepam
Safe, effective for treatment of seizures when administered by paramedics en route to hospital
Wednesday, February 15, 2012

Semuloparin Prophylaxis Effective in Cancer Patients
Reduces incidence of thromboembolic events during chemo, with no increase in major bleeding
Wednesday, February 15, 2012

Topical Corticosteroids Impair Restoration of Skin Barrier
Corticosteroids OK for acute atopic dermatitis, but calcineurin inhibitors better for long-term treatment
Wednesday, February 15, 2012

New Data Published on Safety of Leflunomide in Pregnancy
Data provide some reassurance to women exposed to leflunomide before or during pregnancy
Wednesday, February 15, 2012

Vitamin D Doesn't Improve Cardiac Measures in CKD Patients
No improvements in left ventricular mass, measures of diastolic dysfunction with paricalcitol therapy
Wednesday, February 15, 2012

Hemoglobin A1c, Fasting Plasma Glucose Relationship Studied
Oral therapies impact relationship; should be considered when interpreting A1C levels
Wednesday, February 15, 2012

Study Finds Antibiotic for Acute Rhinosinusitis Is Not Helpful
After three days, no significant symptom difference between treatment with amoxicillin and placebo
Tuesday, February 14, 2012

Supplements Don't Prevent Cancer in Cardiac Patients
Dietary supplements of B vitamins, folate, omega-3 not linked to improved cancer outcomes
Tuesday, February 14, 2012

Patient Satisfaction Linked to Varied Health Care Utilization
Satisfaction linked to lower emergency department use but increased admissions, mortality, costs
Tuesday, February 14, 2012

Zioptan Eyedrops Approved for Glaucoma, Ocular Hypertension
Product should not be used by children or by pregnant women
Monday, February 13, 2012

Guidelines for VTE Prophylaxis in Nonsurgical Patients Issued
Guidelines apply to acute and critical patients, outpatients with cancer, long-distance travelers
Thursday, February 09, 2012

Intracerebroventricular Opioid Infusion Feasible at Home
Effective for treatment of refractory pain in terminal patients; low incidence of adverse events
Thursday, February 09, 2012

Testosterone Patches Improve Low Sexual Desire Disorder
Transdermal testosterone patches relieve symptoms in postmenopausal women
Thursday, February 09, 2012

Fen-Phen Derivative Likely Caused >1,000 Deaths in France
From 1976 to 2009, drug may have contributed to approximately 3,100 hospitalizations, 1,300 deaths
Thursday, February 09, 2012

Prescription Shampoo Approved to Treat Head Lice
Sklice is sanctioned for children as young as 6 months
Wednesday, February 08, 2012

Cefpodoxime Not Recommended for Acute, Uncomplicated Cystitis
Cefpodoxime found inferior to ciprofloxacin in achieving clinical cure
Tuesday, February 07, 2012

New Guidelines Recommend Metformin in Type 2 Diabetes
Monotherapy recommended if lifestyle change inadequate; add second agent if necessary
Tuesday, February 07, 2012

Three 'Targeted' Cancer Drugs Up Risk of Fatal Adverse Events
No differences found in rates of fatal adverse events between VEGFR TKIs or by tumor types
Tuesday, February 07, 2012

Breast Cancer Prevention Drug Linked to Bone Loss
Exemestane increases bone loss despite calcium and vitamin D supplementation
Tuesday, February 07, 2012

Fluoxetine, Venlafaxine Tied to Drop in Adult Suicide Behaviors
For youth, no difference in suicide thoughts or behavior with antidepressant treatment
Monday, February 06, 2012

Mechanism for Metabolic Effects of Resveratrol Elucidated
Resveratrol inhibits phosphodiesterase 4 in mice, resulting in indirect activation of s irtuin 1
Monday, February 06, 2012

Noroviruses Are Leading Cause of Hospital Infections
Particularly in nonacute care setting; often leading to unit closure
Monday, February 06, 2012

RA Drug Trial Funding Source Not Linked to Outcome
Positive outcomes are not more likely in industry-funded rheumatoid arthritis drug trials
Monday, February 06, 2012

Direct to Consumer Statin Web Sites of Poor Quality
Internet sites are prevalent, but information on safe use and side effects flawed
Thursday, February 02, 2012

Ghrelin Stimulates Food Intake During Cisplatin-Based Chemo
Also minimizes adverse effects related to anorexia and nausea for esophageal cancer patients
Thursday, February 02, 2012

AHA: Apixaban Beats Aspirin for Stroke Prevention in A-Fib
More effective for patients with a-fib, prior stroke history, unsuitability for vitamin K antagonists
Thursday, February 02, 2012

Occasional Hard Drug Use in Mid-Life Hikes Mortality Risks
Trajectory analysis shows significantly increased risk for early frequent/later occasional users
Thursday, February 02, 2012

AAP: Childhood Vaccination Schedules Approved for 2012
Three schedules and accompanying footnotes offer new clarifications and guidance
Wednesday, February 01, 2012

No Improvement in C-Peptide Levels With GAD-Alum
GAD-alum and placebo produce similar C-peptide decreases in children with type 1 diabetes
Wednesday, February 01, 2012

Oral Ulipristal Acetate Controls Uterine Fibroid Bleeding
Two studies show efficacy of oral ulipristal acetate compared with placebo, leuprolide acetate
Wednesday, February 01, 2012

Proton Pump Inhibitor Use Ups Hip Fracture Risk for Women
More than 50 percent increased risk for postmenopausal current or former smokers
Wednesday, February 01, 2012

Fenofibrate Found Safe in Diabetes With Renal Impairment
Reduced total cardiovascular events in patients with type 2 diabetes and moderate renal impairment
Tuesday, January 31, 2012

Diabetes Drugs Affect Pancreatic Cancer Risk
Metformin linked to lower risk in women; sulfonylureas, insulin associated with higher risk
Tuesday, January 31, 2012

Erivedge Approved to Treat Basal Cell Carinoma
The most common skin cancer
Monday, January 30, 2012

Meta-Analysis: Statin Therapy Equally Effective in Women, Men
Statins significantly decrease cardiovascular events, all-cause mortality in both sexes
Monday, January 30, 2012

Antiretroviral Medications Linked to Cleft Deformities
Drugs to keep HIV-infected women from transmitting virus to fetus may trigger cleft defects
Monday, January 30, 2012

More Research Needed on Weaning of Addicted Infants
Nurseries need a plan for the evaluation, treatment of infants at risk for or showing withdrawal
Monday, January 30, 2012

Bydureon Approved for Type 2 Diabetes
A once-weekly injection
Friday, January 27, 2012

No Complications From Using Stored Red Blood Cells
Short-term complication status similar in fresh versus standard issue red blood cell transfusions
Friday, January 27, 2012

Comparable Clinical Activity for Low-, High-Dose Clofarabine
More adverse effects seen for high dose in patients with higher-risk myelodysplastic syndrome
Friday, January 27, 2012

ACE Inhibitors Not Linked to Improved Outcomes After ACS
Prior use of ACE inhibitors does not improve in-hospital outcomes after acute coronary syndrome
Thursday, January 26, 2012

Survival Reduced for Patients With Cancer Who Have Diabetes
Type of cancer and diabetes treatment influence survival
Thursday, January 26, 2012

Positive Affirmation Improves Medication Adherence
But, does not significantly reduce blood pressure in African-Americans with hypertension
Thursday, January 26, 2012

Sildenafil Shows Potential for Lymphatic Malformations
Regression of congenital vascular anomalies seen in three children treated with oral sildenafil
Wednesday, January 25, 2012

Oxaliplatin Improves Survival for Colorectal Cancer Patients
Improvements found in community settings, even amongst older and minority populations
Wednesday, January 25, 2012

Unemployed Have Poorer Mental and Physical Health
And are less likely to receive needed medical care and prescriptions
Tuesday, January 24, 2012

Lansoprazole Does Not Improve Asthma Control in Children
Treatment with lansoprazole associated with increased number of respiratory infections
Tuesday, January 24, 2012

Anastrozole Sequence Doesn't Significantly Improve Survival
Sequencing tamoxifen and anastrozole provides limited improvement in breast cancer outcome
Tuesday, January 24, 2012

Dutasteride Delays Low-Risk Prostate Cancer Progression
Men under active surveillance for low-risk prostate cancer benefit from adjunct dutasteride
Tuesday, January 24, 2012

HealthGrades IDs Notable Hospitals for Clinical Excellence
If all hospitals performed at this level, thousands of Medicare deaths, complications could be averted
Tuesday, January 24, 2012

Statins May Reduce Risk for HCC in Hep B-Infected Patients
Hepatocellular cancer risk reduced in a dose-dependent manner in hepatitis B-infected patients
Monday, January 23, 2012

Mild-to-Moderate Asthma Frequently Non-Eosinophilic
Nearly half of patients with mild-to-moderate asthma have non-eosinophilic phenotype
Monday, January 23, 2012

Dosing Errors Occur With IV Acetaminophen in Children
Ten-fold overdose may occur in young children; treatment with acetylcysteine may be indicated
Monday, January 23, 2012

Inadequate Hep B Vaccinations for High-Risk Adults
More than half the adults at high risk of infection miss opportunities for vaccinations
Monday, January 23, 2012

Neuromodulators Reduce Pain in Rheumatoid Arthritis
Second study shows no beneficial effect of muscle relaxants on pain in rheumatoid arthritis
Friday, January 20, 2012

Warfarin Patients With Head Trauma Need Second CT Scan
For patients on warfarin, 24-hour observation and repeat CT scan detects delayed bleeding
Friday, January 20, 2012

Taking Two or More Medications Increases Fall Rate
For young and middle-aged adults, taking two or more meds tied to 2.5-fold increase in fall risk
Friday, January 20, 2012

No Autoimmune Safety Signal for Quadrivalent HPV Vaccine
Women vaccinated with HPV4 have no increase in incidence of 16 autoimmune disorders
Friday, January 20, 2012

Contraceptives Eschewed by Half of Teenage Mothers
And many use the lesser effective birth control methods to prevent pregnancy
Thursday, January 19, 2012

Design Flaws Cast Doubt on Million Woman Study
Evidence review suggests that study findings do not adequately satisfy principle of causation
Thursday, January 19, 2012

Chronic Hepatitis C May Benefit From New Antivirals
Phase 2a study indicates virologic response with daclatasvir, asunaprevir treatment
Thursday, January 19, 2012

Bevacizumab Combo Improves Colorectal Cancer Survival
Survival benefits greater with irinotecan-based chemo; but more adverse effects with bevacizumab
Wednesday, January 18, 2012

Circulating Tumor Cells Predict Small-Cell Lung CA Prognosis
Both baseline number and change in CTC following first cycle of chemotherapy prognostic
Wednesday, January 18, 2012

Meningitis B Vaccine Immunogenic in Adolescents
Two doses of four-component Neisseria meningitidis serogroup B vaccine immunogenic
Wednesday, January 18, 2012

Peds Liver Transplant Patients Tolerate Drug Withdrawal
For pediatric living donor liver transplant recipients, immunosuppression withdrawal possible
Wednesday, January 18, 2012

Dual Inhibition of HER2 Beats Single Agent in Breast Cancer
For HER2-positive breast cancer, inhibition with lapatinib and trastuzumab superior to single agent
Tuesday, January 17, 2012

Vitamin D Supplements Do Not Reduce COPD Exacerbations
But, supplementation may benefit COPD patients with severe vitamin D deficiency
Monday, January 16, 2012

Maternal Asthma Meds Not Linked to Most Birth Defects
Few defects positively associated with maternal asthma medication use during early pregnancy
Monday, January 16, 2012

Young Women Often Perceive Their Weight Gain Inaccurately
Race/ethnicity, contraception impact perception, which is frequently inaccurate in young women
Friday, January 13, 2012

U.S. Health Care Expenditure Still Unevenly Distributed
In 2008 and 2009, 1 percent of population account for ~20 percent of spending
Friday, January 13, 2012

Maternal Antidepressants Up Infant Pulmonary Hypertension
Similar risk found across the selective serotonin reuptake inhibitor class of antidepressants
Friday, January 13, 2012

Thromboprophylaxis Rate Low for Knee Arthroplasty in Taiwan
Prophylaxis rate of 2.2 percent may be related to low incidence of post-op venous thromboembolism
Friday, January 13, 2012

Novel Anticancer Agents ID'd From NIH Drug Collection
Quantitative high-throughput drug screening method identifies novel anticancer drug candidates
Thursday, January 12, 2012

Rx Provides Fast Relief of Pain, Urgency of Interstitial Cystitis
Study finds alkalinized lidocaine plus heparin provides 12 hours of relief of pain and urgency
Wednesday, January 11, 2012

Single Oral Azithromycin Dose Effective for Yaws
Oral azithromycin non-inferior to standard benzathine benzylpenicillin for treatment of yaws
Wednesday, January 11, 2012

GLP-1R Agonists Found Effective for Weight Loss
Glucagon-like peptide-1 receptor agonists also reduce blood pressure and total cholesterol
Wednesday, January 11, 2012

Occasional Marijuana Use Not Tied to Adverse Lung Function
Nonlinear association for marijuana exposure and lung function; no adverse effects for low exposure
Tuesday, January 10, 2012

Transdermal Nicotine May Benefit Cognitive Impairment
Cognitive test improvement, but no significant change in clinical global impression
Tuesday, January 10, 2012

Losartan Halts Smoke-Related Lung Damage in Mice
Inhibition of TGF-β normalizes smoke-induced TFG-β signaling and prevents alveolar cell death
Tuesday, January 10, 2012

No Rise in Intussusception After Rotavirus Shot Revival
No increase seen in intussusception discharges since 2006 reintroduction of rotavirus vaccine
Tuesday, January 10, 2012

Benefit of Aspirin in Primary Prevention Questioned
Despite reduction in nonfatal MIs, no reduction seen in cardiovascular death or cancer mortality
Tuesday, January 10, 2012

Nicotine Replacement Therapy Doesn't Avert Smoking Relapse
Likelihood of relapse unaffected by nicotine replacement therapy, with or without counseling
Tuesday, January 10, 2012

Memantine Has No Impact on Cognition in Down's Syndrome
Adults older than 40 with Down's syndrome do not benefit from treatment with memantine
Tuesday, January 10, 2012

Long-Term Prognostic Value of Dobutamine Stress Echo Limited
Long-term predictive value restricted for patients with diabetes unable to take an exercise stress test
Tuesday, January 10, 2012

Statins Increase Diabetes Risk for Postmenopausal Women
Association significant even after adjusting for variables; seen for all types of statins
Monday, January 09, 2012

Acupuncture May Have Minor Effect in Migraine Prevention
Compared with sham treatment, significant reduction in days with migraine at 13 to 16 weeks
Monday, January 09, 2012

Rilonacept Reduces Gout Flares During Acute Urate Lowering Rx
Phase 2 trial shows that rilonacept reduces gout flares during initiation of allopurinol therapy
Monday, January 09, 2012

Hypoglycemia in Intensive Diabetes Control May Up Survival
Inverse relationship seen between number of hypoglycemic episodes and risk of death
Friday, January 06, 2012

HCV Antivirals Cost-Effective for Injecting Drug Users
Model shows antiviral treatment cost-effective when baseline prevalence is less than 60 percent
Friday, January 06, 2012

Frequent Aspirin Use Linked to Aging Macula Disorder
For daily aspirin users, likelihood of disorder increases with increasing severity of AMD
Friday, January 06, 2012

Shedding Persists in Herpes Even With High-Dose Antivirals
Reactivation likely accounts for transmission during therapy; new treatments needed
Thursday, January 05, 2012

HPV Vaccine Doesn't Lull Girls Into Complacency About Sex
Mom, daughter vaccine knowledge, communication tied to ongoing perception of need for safer sex
Thursday, January 05, 2012

Epilepsy, HIV Drug Combination Therapies Require Caution
Coadministration of antiepileptic drugs and antiretrovirals may necessitate dose adjustment
Thursday, January 05, 2012

Montelukast Doesn't Cut Upper Respiratory Infection Incidence
For preschool children, 12-week prophylactic treatment doesn't reduce incidence of URI
Wednesday, January 04, 2012

Metformin Hikes B12 Deficiency in Type 2 Diabetes
OTC supplements fail to correct B12 deficiencies in type 2 diabetes, regardless of metformin therapy
Thursday, December 29, 2011

Oseltamivir-Resistant H1N1 Identified in Australia
Between May and August 2011, resistant viruses with H275Y substitution ID'd in 29 of 182 patients
Thursday, December 29, 2011

Enoxaparin Doesn't Reduce Death Rate for Acutely Ill
Death from any cause at 30 days and rates of major bleeding similar with enoxaparin, placebo
Wednesday, December 28, 2011

Bevacizumab Ups Progression-Free Survival in Ovarian Cancer
Two studies demonstrate the benefit of bevacizumab added to standard therapy
Wednesday, December 28, 2011

Study Compares Onset of Action of Two Types of Botulinum Toxin
AbobotulinumtoxinA yields more significant improvements in crow's feet at day 4
Monday, December 26, 2011

Extended Nevirapine Reduces Breastfeeding HIV Transmission
Results in 54 percent reduction in mother-to-child HIV transmission during breastfeeding
Friday, December 23, 2011

Correcting Anemia Reduces Odds of Renal Transplant Failure
Complete anemia correction reduces progression to chronic allograft nephropathy post-transplant
Thursday, December 22, 2011

Postmenopausal HRT Improves Sexual Function
HRT, dehydroepiandrosterone, tibolone all improve quality of sexual function and frequency
Thursday, December 22, 2011

Isentress Approval Expanded to Include Children and Teens
HIV drug expanded to include children and adolescents ages 2 to 18
Wednesday, December 21, 2011

Cixutumumab Tolerated for Pediatric Refractory Solid Tumors
Recommended phase II pediatric dose is 9 mg/kg intravenously once per week
Wednesday, December 21, 2011

Aflibercept Shows Clinical Activity for Malignant Ascites
Ups time to paracentesis in advanced chemo-resistant ovarian cancer with recurrent ascites
Wednesday, December 21, 2011

NCHS: Poisonings Are Leading Cause of Injury Deaths
In 2008, poisoning deaths were main cause of injury death, with almost 90 percent due to drugs
Wednesday, December 21, 2011

Vitamin D, Calcium Found to Cut Fracture, Cancer Risk
A second study offers no evidence that vitamin D supplementation prevents cardiovascular disease
Tuesday, December 20, 2011

Little Risk to Offspring From Maternal Inhaled Steroids
But may be associated with increased risk of endocrine/metabolic disorders
Tuesday, December 20, 2011

Combo Therapies in Psoriasis More Effective Than Monotherapy
Adding phototherapy to topical monotherapy improves psoriasis clearance
Monday, December 19, 2011

Ovarian Failure Risk Differs with Chemo Type in Hodgkin's
Significant risk from alkylating chemo; little risk from nonalkylating for those less than age 32
Monday, December 19, 2011

Laws Impact School Support for Anaphylaxis Management
Gaps exist in awareness of anaphylaxis procedure and EpiPen administration technique
Monday, December 19, 2011

Omega-3 Index Not Linked to Bleeding in Acute MI
No link between red blood cell omega-3 fatty acid index and serious or mild to moderate bleeding
Monday, December 19, 2011

Suboptimal Intensive Statin Therapy Use After ACS
Poor persistence after discharge for newly initiated IST after acute coronary syndrome
Monday, December 19, 2011

Vaginal Progesterone Cuts Preterm Birth, Neonatal Deaths
Reduces preterm birth, neonatal morbidity and mortality in asymptomatic women with short cervix
Friday, December 16, 2011

High-Dose Aspirin Impacts Fibrin Network in Diabetes
Aspirin at 320 mg increases fibrin network permeability in patients with type 1 diabetes
Friday, December 16, 2011

Adjuvant Bevacizumab Feasible for Nasopharyngeal Cancer
Adjuvant treatment is not associated with grade 3 to 4 hemorrhages or grade 5 adverse events
Friday, December 16, 2011

Chemotherapy Options ID'd for Cisplatin-Unfit Urothelial Cancer
Carboplatin-based regimens with gemcitabine or methotrexate/vinblastine show similar efficacy
Thursday, December 15, 2011

Statins Lower Death Risk in Adults Hospitalized With Flu
Statins given before or during hospitalization reduce mortality in adults with influenza
Thursday, December 15, 2011

ASH: Most Cancer-Related Clots Occur in Outpatients
Of the venous thromboembolism cases in patients with cancer, 78.3 percent occur in outpatients
Tuesday, December 13, 2011

No Increase in Birth Defects for Offspring of Cancer Survivors
Parental childhood exposure to chemo, radiation not tied to congenital anomalies in offspring
Tuesday, December 13, 2011

Khat Ups Adverse Outcomes in Acute Coronary Syndrome
Khat chewers with acute coronary syndrome have increased risk of death, cardiovascular events
Monday, December 12, 2011

ADHD Med Use Not Tied to Increased Cardiovascular Risk
Current, new ADHD medication users do not have higher risk of MI, sudden cardiac death, stroke
Monday, December 12, 2011

ASH: Aspirin Safe and Effective for Preventing VTE Recurrence
After first unprovoked VTE, long-term aspirin after standard anticoagulant therapy decreases recurrence
Monday, December 12, 2011

Chemo, Radiation Worsen Cognition in Breast CA Survivors
However, hormonal therapy does not predict changes in cognitive functioning over time
Monday, December 12, 2011

ASH: Gene Therapy Shows Promise for Hemophilia B
Administration of virus vector expressing factor IX transgene prevents spontaneous bleeding
Monday, December 12, 2011

ASH: Hydroxyurea Safe, Effective in Pediatric Sickle Cell
And, two-year treatment of young children with hydroxyurea is not associated with genotoxicity
Monday, December 12, 2011

SABCS: Adjuvant Bevacizumab Ups Progression-Free Survival
Statistically significant improvement seen in Independent Review Committee assessment
Thursday, December 08, 2011

SABCS: Breast Cancer Survival Up With Everolimus + Exemestane
And, improved progression-free survival with add-on pertuzumab in HER2+ metastatic cancer
Thursday, December 08, 2011

Rifapentine Plus Isoniazid Noninferior to Isoniazid Alone
Higher completion rate with three months of combo therapy versus nine months of isoniazid
Wednesday, December 07, 2011

Intranasal Vaccine Effective Against Norwalk Virus Illness
Two doses of norovirus virus-like particle vaccine protects against gastroenteritis, infection
Wednesday, December 07, 2011

SABCS: Long-Term Benefits for Zoledronic Acid in Breast Cancer
And, for postmenopausal women, immediate ZOL therapy reduces risk of disease-free survival events
Wednesday, December 07, 2011

Role of Environmental Factors in Breast Cancer Explored
IOM finds consistent evidence for links with combo HRT, postmenopausal weight gain, radiation, alcohol
Wednesday, December 07, 2011

SABCS: Dyslipidemia, Obesity After 60 Tied to Breast CA Risk
Diabetes, obesity after age 60, abnormally low lipid levels linked to increased breast cancer risk
Wednesday, December 07, 2011

Spending on Depression Up From 1996 to 2005
Increased Florida Medicaid spending but minimal improvements in quality of care
Wednesday, December 07, 2011

Bisphosphonate Use Ups Knee, Hip Implant Survival
Almost two-fold increase seen in implant survival time after total knee or hip arthroplasty
Wednesday, December 07, 2011

Androgen Deprivation in Prostate Cancer Not Tied to CVD Death
But, ADT is associated with reduced risk of prostate cancer-specific mortality, all-cause death
Tuesday, December 06, 2011

FDA and FTC Crack Down on Homeopathic Weight Loss Drug
Marketers of off-label HCG issued warning letters
Tuesday, December 06, 2011

Preventive Asthma Medication Use Increasing in Children
Lower use reported among minority children, adolescents, and uninsured
Tuesday, December 06, 2011

Similar Efficacy Among Second-Generation Antidepressants
But different onset of action and adverse events in adults with major depressive disorder
Monday, December 05, 2011

Eating Little or No Fish Ups Young Women's CVD Risk
Women who never eat fish have three-fold higher disease risk than those who eat fish every week
Monday, December 05, 2011

Medical Students Fail to ID Hand Hygiene Indications
Preclinical phase medical students lack knowledge about hand disinfection indications
Monday, December 05, 2011

Fluoxetine Improves Repetitive Behaviors in Adult ASDs
Improvement in Yale Brown Obsessive Compulsive subscale, Clinical Global Impression scale
Monday, December 05, 2011

AES: Prenatal Valproate Exposure Tied to Autism Risk
More than double risk of autism spectrum disorder; more than four-fold risk of childhood autism
Monday, December 05, 2011

Youth Often Get Hypertension Rx From PCPs Who Treat Adults
Whites, older adolescents, and those with comorbidity more likely to receive prescription
Monday, December 05, 2011

Belimumab + Standard Therapy Efficacious for Lupus
Combo improves Systemic Lupus Erythematosus Responder Index response rate
Monday, December 05, 2011

Green Tea Polyphenol Inhibits HCV Entry Into Hepatocytes
Epigallocatechin-3-gallate blocks infection of cells by extracellular virions, cell-to-cell spread
Monday, December 05, 2011

Cold Sore Susceptibility Linked to SNPs on C21orf91
Association seen in linkage analysis, parental transmission disequilibrium testing
Friday, December 02, 2011

Salvianolic Acid B Suppress Maturation of Dendritic Cells
Sal B effects on human monocyte-derived dendritic cell maturation blocked by PPARγ siRNA
Friday, December 02, 2011

Diet High in Antioxidants Cuts Stroke Risk for Women
Reduction in total stroke for those without prior CVD; hemorrhagic stroke for those with history
Thursday, December 01, 2011

First Generic Lipitor Approved
Widely used statin drug helps lower bad cholesterol
Thursday, December 01, 2011

Parental CA Therapy Not Tied to Genetic Defects in Offspring
Neither parental chemo nor preconception gonad irradiation linked to genetic defects in children
Thursday, December 01, 2011

MK-0941 Safe, Efficacious for Short-Term Glucose Control
Improvements in A1C, two-hour postmeal glucose seen at week 14 were not sustained by week 30
Thursday, December 01, 2011

Learning Assessment Tool IDs R.N. Educational Needs
Pediatric procedural sedation education needs identified through questionnaire
Thursday, December 01, 2011

Anticoagulant Self-Monitoring Safe Option for Suitable Patients
Self-monitoring, self-management associated with significant reduction in thromboembolic events
Thursday, December 01, 2011

IL-2 Tied to Regulatory T-Cell Expansion in Graft-Versus-Host
And, IL-2 associated with Treg recovery and clinical improvement in HCV-induced vasculitis
Wednesday, November 30, 2011

Delayed Acyclovir in Neonates With Herpes Ups Mortality
With overall in-hospital mortality rate of 7.3 percent for neonates with herpes simplex infection
Wednesday, November 30, 2011

Intensified Immunochemotherapy Benefits B-Cell Lymphoma
Intensified immunochemotherapy ups overall, event, progression-free survival in large B-cell lymphoma
Tuesday, November 29, 2011

Concomitant MMRV With PCV-7 Highly Immunogenic, Safe
Measles, mumps, rubella, varicella vaccine co-administered with pneumococcal vaccine safe
Tuesday, November 29, 2011

NSAID, Statin Use Cuts Cancer Risk in Barrett's Esophagus
NSAIDs, statins each reduce neoplastic progression risk; additive benefit with combined use
Tuesday, November 29, 2011

Opioid Rx for Chronic Abdominal Pain Up Over Last Decade
Most commonly prescribed to 25- to 40-year-olds; least commonly to uninsured, African-Americans
Tuesday, November 29, 2011

High-Performing Docs Learn Equally From Success, Failure
High performers learn from successes, failures; low performers have asymmetric learning rates
Monday, November 28, 2011

Chronic Disease Management Ups Smoking Abstinence
And, nicotine therapy during practice quit attempt linked to increased incidence of quit attempts
Monday, November 28, 2011

Many Pediatricians OK With Alternative Vaccine Schedules
Pediatricians least willing to consider ACIS for H. influenza type b, DTaP, pneumococcal conjugate
Monday, November 28, 2011

GIP Identified As Bifunctional Blood Glucose Stabilizer
Glucose-dependent insulinotropic polypeptide infusion affects glucagon levels, insulin release
Monday, November 28, 2011

Everolimus Ups Survival in Carcinoid Syndrome
For patients with advanced neuroendocrine tumors, octreotide LAR + everolimus improves PFS
Monday, November 28, 2011

Afternoon Shots Up Post-Immunization Sleep Duration
Prophylactic acetaminophen not significant predictor of post-shot sleep duration
Monday, November 28, 2011

Dabigatran Poses Challenge in Treating Injured Patients
Due to lack of readily available methods to assess degree of anticoagulation, and reverse effects
Wednesday, November 23, 2011

Drugs ID'd in Most Older Adult Emergency Hospitalizations
Warfarin, insulin, oral antiplatelets, hypoglycemics implicated in most emergency hospitalizations
Wednesday, November 23, 2011

Similar Asthma Outcomes With Daily, Intermittent Budesonide
But, daily regimen leads to greater budesonide exposure than intermittent regimen in children
Wednesday, November 23, 2011

Adjuvant Capecitabine Does Not Improve Breast Cancer Survival
Adding capecitabine to docetaxel, epirubicin, cyclophosphamide doesn't up survival
Wednesday, November 23, 2011

Staggered Acetaminophen Overdose Tied to Poor Outcome
Delayed presentation after overdose associated with death/liver transplantation
Wednesday, November 23, 2011

Prolonged LDL-Lowering Statin Treatment Beneficial, Safe
Benefits persist without increase in mortality, morbidity for at least five years after treatment
Wednesday, November 23, 2011

Alendronate Ups BMD in Patients Taking Steroids for Skin Diseases
Bone mineral density increased at lumbar spine, femoral neck in immunobullous disorders
Wednesday, November 23, 2011

Continuous Glucose Monitoring Improves Glycemic Control
Real-time monitoring gives patients with type 2 diabetes not on prandial insulin sustained control
Wednesday, November 23, 2011

Breast CA, Tenderness Linked in Women on Combo HRT
CEE + MPA doubles the risk of breast cancer in women with baseline breast tenderness
Tuesday, November 22, 2011

Process Attributes Most Impact Psoriasis Therapy Choice
Treatment location, probability of benefit, delivery method affects patients' treatment preference
Tuesday, November 22, 2011

Oral Antibiotic Use in Acne Tied to Reported Pharyngitis
Odds of reporting pharyngitis more than three times higher for patients taking oral antibiotics
Monday, November 21, 2011

Nonpunitive Method Improves Medical Error Reporting
Most common errors: misfiled or incorrectly entered patient info
Monday, November 21, 2011

Grape Seed Extract Lowers Squamous Cell Carcinoma Risk
Use of multivitamins is linked to borderline significant reduction in the risk of SCC
Monday, November 21, 2011

Post-Bat Exposure Prophylaxis Up in New York
Increased numbers of bats submitted for rabies testing, reports of exposure, and use of PEP
Friday, November 18, 2011

Minoxidil Foam Is Effective in Androgenic Alopecia
Once-daily 5 percent MTF is as effective as twice-daily 2 percent topical solution
Friday, November 18, 2011

Growth Hormone Replacement Ups Diabetes Incidence
Higher plasma glucose, HbA1c in adult patients with growth hormone deficiency
Friday, November 18, 2011

Rapid Safety Monitoring of H1N1 Vaccine Feasible
Uses modern technology to collect rapid self-reported safety data in large numbers of patients
Friday, November 18, 2011

Long-Term Antiepileptic Drug Therapy Ups Atherosclerosis
Carbamazepine, phenytoin, valproic acid, but not lamotrigine alter markers of vascular risk
Friday, November 18, 2011

Hib Vaccine Has Cut H. influenzae Incidence Dramatically
Burden of disease is highest in youngest and oldest age groups
Thursday, November 17, 2011

Tamoxifen Discontinuation Rate High in Male Breast Cancer
Majority of patients experience one or more toxic effect during tamoxifen treatment
Thursday, November 17, 2011

AHA: CYP2C19*2 Carriers Need Triple Clopidogrel Dosing
Similar platelet reactivity with 225 mg in CYP2C19*2 heterozygotes, 75 mg in noncarriers
Wednesday, November 16, 2011

Mycophenolate Mofetil Beats Azathioprine in Lupus Nephritis
With superior maintenance of renal response to treatment, and superior prevention of relapse
Wednesday, November 16, 2011

AHA: Drug-Eluting Balloons Promising Alternative to Stents
And, PCI with drug-eluting balloons also feasible in patients at risk of bleeding complications
Wednesday, November 16, 2011

Breast Cancer Survivors Have Impaired Neurological Function
Additional reductions in prefrontal function, decreased executive function post-chemo
Wednesday, November 16, 2011

Denosumab Improves Bone-Metastasis-Free Survival
Delays time to first bone mets for patients with high-risk castration-resistant prostate cancer
Wednesday, November 16, 2011

U.S. Oncologists Rate Selves Highly in Pain Management
But, acknowledge barriers to optimal care, and consider quality of training to be poor
Tuesday, November 15, 2011

AHA: Adding Niacin Doesn't Beat Statin Alone for CV Risk
Although addition of niacin increases HDL cholesterol, lowers triglyceride and LDL cholesterol levels
Tuesday, November 15, 2011

AHA: Evacetrapib Alone/With Statins Useful in Dyslipidemia
Significantly increases HDL cholesterol and reduces LDL cholesterol compared to statins alone
Tuesday, November 15, 2011

Global Oral Contraceptive Use Tied to Prostate Cancer Incidence
Ecological study shows oral contraceptive use linked to prostate cancer incidence, death worldwide
Tuesday, November 15, 2011

U.S. Teen Vaccination Coverage Up From 2006 to 2009
Could be bettered via simultaneous administration, provider endorsement, parental awareness
Monday, November 14, 2011

Delayed Acyclovir Ups Hospital Stay for Eczema Herpeticum
One day delay in starting acylovir ups hospital stay by 11 percent in pediatric eczema herpeticum
Monday, November 14, 2011

AHA: Dronedarone Detrimental for Certain A-Fib Patients
Counter to hypothesis, agent may cause major vascular events
Monday, November 14, 2011

Copayment Elimination Ups Post-MI Medication Adherence
Enhanced coverage also decreases patient spending without increasing overall health costs
Monday, November 14, 2011

Rivaroxaban Improves Acute Coronary Syndrome Outcomes
Apixaban thromboprophylaxis better than enoxaparin; adjuvant vorapaxar not effective/safe
Monday, November 14, 2011

AHA: Cardiac Stem Cells Show Promise in Heart Failure
Promising phase 1 trial results on their safety, efficacy in post-MI heart failure
Monday, November 14, 2011

SfN: Exercise Tied to Neuronal Changes in Fibromyalgia
Increased pain sensation following medication withdrawal is improved by aerobic exercise
Monday, November 14, 2011

AHA: Single AMG145 Dose Lowers LDL-Cholesterol Levels
AMG145 lowers LDL-C, total cholesterol, apo-B, but has no effect on triglycerides, HDL-C, apo-A1
Monday, November 14, 2011

Diazoxide Lowers Glucose Production in Humans, Rats
Hypothalamic KATP channels involved in regulation of endogenous glucose production
Friday, November 11, 2011

Methamphetamine Linked to Increased Schizophrenia Risk
Increased risk with methamphetamine-use disorder; similar to risk for cannabis-use disorder
Friday, November 11, 2011

About 15,000 Intentional Poisoning ER Visits in 2009
Alcohol and drug combinations involved in 60 percent of these emergency department visits
Friday, November 11, 2011

Estimated Flu Incidence of 90 Million for 2008 in Under-5s
Nearly all flu-associated acute lower respiratory infection deaths occur in developing countries
Friday, November 11, 2011

Community-Based Treatment Improves Pneumonia Outcomes
Community case management reduces treatment failure rate in children compared to standard care
Friday, November 11, 2011

Zostavax Still Recommended Only for Those 60 and Over
Supply and data issues influence committee decision
Thursday, November 10, 2011

Glove Use Linked to Reduced Hand Hygiene Compliance
Gloves often worn when not indicated, and not worn when indicated
Thursday, November 10, 2011

Pre-Knee Replacement Use of Opioids Tied to Complications
Significantly higher complication rate and greater need for pain management referral
Thursday, November 10, 2011

Evidence Shows Reduced Sodium Intake Lowers BP
But increase seen in levels of renin, aldosterone, adrenaline, noradrenaline, cholesterol, lipids
Thursday, November 10, 2011

Epigenetic Therapy Shows Promise in Progressive NSCLC
Demethylation of epigenetically silenced genes associated with lung cancer seen in blood samples
Thursday, November 10, 2011

Alcoholic Hepatitis Combo Meds Don't Help Six-Month Survival
But early liver transplant improves survival in medically unresponsive severe alcoholic hepatitis
Wednesday, November 09, 2011

Trilipix Not Found to Reduce Risk of Coronary Events
FDA advises physicians to counsel patients on risks and benefits
Wednesday, November 09, 2011

Varying Response to Etanercept in Juvenile Arthritis
Excellent response tied to low disability scores, prior DMARD use, younger age at onset
Wednesday, November 09, 2011

Adjuvant Bevacizumab Feasible in Ovarian Cancer
Progression-free survival similar to IP, IV therapy; higher risk of bowel perforation/obstruction
Wednesday, November 09, 2011

Wait-and-See Policy Feasible for Some With Rectal Cancer
Using strict selection criteria and follow-up, wait-and-see results in promising outcomes
Wednesday, November 09, 2011

TNF-α Antagonists Do Not Up Infection Hospitalizations
In autoimmune disease, infection hospitalization risk similar to that with nonbiologic medication
Wednesday, November 09, 2011

HPV-16/18 Efficacious Against CIN3+, Adenocarcinoma in Situ
And, vaccine shows cross-protective efficacy against four oncogenic non-vaccine HPV types
Wednesday, November 09, 2011

Biolimus Stents Noninferior to Sirolimus Stents
Biolimus-eluting stents are noninferior to sirolimus eluting stents in coronary artery disease
Wednesday, November 09, 2011

Poxviral Vaccine Benefits Some With Ovarian, Breast Cancer
Some patients with limited tumor burden, minimal chemo exposure benefit from monthly vaccine
Tuesday, November 08, 2011

No Added Benefits of Cranial Bypass in Stroke Prevention
For patients with atherosclerotic internal carotid artery occlusion, surgery doesn't cut stroke risk
Tuesday, November 08, 2011

Evidence Lacking for Pridopidine Efficacy in Huntington's Disease
Although treatment did not meet prespecified efficacy, potential effect on motor phenotype seen
Tuesday, November 08, 2011

Ridaforolimus Promising for Treating Advanced Sarcomas
Clinical benefit seen for patients with advanced sarcomas of different histopathologic subtypes
Tuesday, November 08, 2011

Substance Use, Abuse Highest Among Native American Teens
Marijuana, then analgesic opioids most commonly used illegal drugs in all racial/ethnic groups
Tuesday, November 08, 2011

Great Achievement at Young Age Function of Time, Not Field
Age dynamics tied to proportion of theoretical work, age of attainment of foundation knowledge
Monday, November 07, 2011

ACAAI: Statin Treatment Tied to Worse Asthma Control
Worsened FEV1, increased nocturnal awakenings, rescue medication use, and daytime symptoms
Monday, November 07, 2011

ACAAI: RNS60 Safe, Promising for Mild to Moderate Asthma
RNS60 improves physiological parameters without adverse events or safety concerns in Phase I trial
Monday, November 07, 2011

Impact of Exercise Lessened by Metformin in Prediabetes
No significant difference for exercise, metformin, combo; but metformin attenuates exercise effect
Monday, November 07, 2011

Exenatide Tied to Modest Weight Loss for Obese Women
A subset of women, termed high responders, lost 5 percent or more of their body weight
Monday, November 07, 2011

K2 Linked to Cases of ST-Elevation Myocardial Infarction
Awareness of K2 health implications should be raised after MIs within days of reported K2 use
Monday, November 07, 2011

Causal Link Suggested Between Acetaminophen Use, Asthma
Children at risk or with asthma should avoid acetaminophen until safety is documented
Monday, November 07, 2011

ACR: Vitamin D Beneficial in Systemic Lupus Erythematosus
And, interferon-α-kinoid immunization is safe, shows promise for SLE
Monday, November 07, 2011

Statin Use in BAV Stenosis Tied to Ascending Aortic Size
Significantly reduced ascending aortic size in patients treated with statins versus untreated
Friday, November 04, 2011

FDA Enhancing Surveillance for Anti-TNF Malignancy
Physicians requested to be alert, report cases of hepatosplenic T-cell lymphoma
Friday, November 04, 2011

Varenicline Tied to Increased Risk of Suicidal Behavior
Varenicline ups suicide/self-injury or depression more than bupropion, nicotine replacement
Friday, November 04, 2011

Receptionists Contribute to Safety of Repeat Prescriptions
Clinicians often unaware of input of receptionists and administrative staff in repeat prescribing
Friday, November 04, 2011

EGFR Level Predicts Survival Benefit of Cetuximab in NSCLC
Patients with high EGFR expression survive longer if they receive cetuximab in addition to chemo
Friday, November 04, 2011

Rooms of Patients With A. baumannii Often Contaminated
Supply carts, floors, infusion pumps, ventilator touch pads are most commonly contaminated
Friday, November 04, 2011

Carisoprodol-Related Emergency Visits Up in United States
Most ER visits involving carisoprodol involve another drug; usually narcotics or benzodiazepines
Thursday, November 03, 2011

ZDN/IFN-α Ups Survival in T-Cell Leukemia/Lymphoma
Combination of zidovudine, interferon α with chemo prolongs survival in acute, lymphoma ATLL
Thursday, November 03, 2011

No Concerning Patterns Seen With H1N1 Vaccine in Pregnancy
Reports to the Vaccine Adverse Event Reporting System indicate 2009 H1N1 vaccination is safe
Thursday, November 03, 2011

Prophylactic Therapy Reduces Bleeding in Hemophilia A
Prophylaxis with anti-inhibitor coagulant complex cuts bleeding events versus on-demand therapy
Wednesday, November 02, 2011

Ivacaftor Safe, Efficacious for Cystic Fibrosis
Improves pulmonary exacerbation, respiratory symptoms, weight, sweat chloride levels
Wednesday, November 02, 2011

CDC: Opioid Overdoses Have Reached Epidemic Proportions
Overdose death rates, sales, OPR-related treatment admissions increased between 1999 and 2008
Wednesday, November 02, 2011

HPV Testing in Self-Collected Samples Has High Sensitivity
Home-HPV testing is more sensitive than cervical cytology, but has lower positive predictive value
Wednesday, November 02, 2011

ADHD Drug Use Not Tied to Serious Cardiovascular Events
Current ADHD drug use does not significantly increase risk of stroke, MI, cardiac death
Tuesday, November 01, 2011

Exparel Approved for Post-Surgery Pain
Provides relief up to 72 hours
Monday, October 31, 2011

Universal Teen Substance Use Approach Recommended
Pediatricians should recommend screening, brief intervention, and/or referral to treatment
Monday, October 31, 2011

APHA: Rates of Personal Belief Vaccination Exemptions Are Up
Ten percent of kindergarteners in California attend school with rates of PBE exceeding 5 percent
Monday, October 31, 2011

Pre-Op Erythropoietin Reduces Need for Peri-Op Transfusion
Also reduces the number of units of erythrocytes transfused during and after surgery
Monday, October 31, 2011

Complete Remission for Many With Nonsyndromic Epilepsy
Two-year seizure outcome and underlying cause offer imperfect prediction of complete remission
Monday, October 31, 2011

Switching From IV to Oral Meds Cuts Health Care Costs
In patients eligible for oral intake, switch from IV to oral equivalents cuts hospital costs
Monday, October 31, 2011

Thalidomide Effective, Safe in GI Vascular Malformations
No severe adverse effects, minor side effects common with thalidomide treatment
Friday, October 28, 2011

Nonclinical Factors Impact Back Pain Treatment Decisions
Patient presentation, socioeconomic status, gender influence physician treatment decisions
Friday, October 28, 2011

Long-Term Aspirin Use Lowers CRC Risk in Lynch Syndrome
Long-term aspirin use benefits individuals with increased hereditary risk of colorectal cancer
Friday, October 28, 2011

Cannabinoid Receptor Tied to Cognitive Chaos
Disrupted hippocampal and mPFC coordination may induce impaired memory and cognition in rats
Thursday, October 27, 2011

Study Finds Statins Don't Slow Atherosclerosis in Pediatric SLE
No difference in mean-mean common carotid intima-media thickening with atorvastatin, placebo
Thursday, October 27, 2011

CDC to Discontinue Provision of Botulinum Toxoid Vaccine
Decision applies to workers in occupational risk of exposure
Thursday, October 27, 2011

Obesity Tied to Impaired Immunity After Flu Vaccine
Reduced levels of influenza antibody titers, decreased CD8+ T-cell responses in obese
Thursday, October 27, 2011

Ovarian Stimulation Ups Risk of Ovarian Tumors in Later Life
Increased risk of ovarian stimulation for IVF seen in particular with borderline ovarian tumors
Thursday, October 27, 2011

Bedside Geriatric Assessment Feasible in Elderly With AML
Adds information to standard oncology assessment in older patients with acute myelogenous leukemia
Thursday, October 27, 2011

Briakinumab More Effective Than Methotrexate in Psoriasis
Although more frequent serious infections and cancers seen with briakinumab
Thursday, October 27, 2011

qHPV Vaccine Efficacious in Anal Intraepithelial Neoplasia
Quadrivalent vaccine cuts rate of anal intraepithelial neoplasia in men who have sex with men
Wednesday, October 26, 2011

Bedtime Medications Offer Better BP Control in CKD
Taking at least one medication at bedtime reduces sleep-time, ambulatory BP, cardiovascular events
Wednesday, October 26, 2011

AAPS: Transdermal Patch Shows Promise for HIV Therapy
IQP-0410 transdermal patch is non-toxic, doesn't degrade, and has potent in vitro activity
Wednesday, October 26, 2011

Ghost Authorship Prevalent in About One-Fifth of Articles
Prevalence of honorary, ghost authorship, down from 29.2 to 21.0 percent from 1996 to 2008
Wednesday, October 26, 2011

Newer Progestogen Types in the Pill Tied to Higher VTE Risk
Increased risk for users of pills with desogestrel, gestodene, drospirenone versus levonorgestrel
Wednesday, October 26, 2011

Evidence Suggests Variable Effectiveness for Flu Vaccine
Randomized controlled trials indicate vaccine efficacy varies between seasons, age groups
Wednesday, October 26, 2011

Clinical, Genetic Factors Linked to Early Stent Thrombosis
Independent association for three genes, two clopidogrel-related factors, clinical factors
Tuesday, October 25, 2011

FDA: Xigris Pulled From Global Market
Drug failed to show survival benefit in severe sepsis
Tuesday, October 25, 2011

CDC Recommends HPV Vaccination in Males
Hope is to reduce spread of HPV
Tuesday, October 25, 2011

Capecitabine First-Line Option in Advanced Breast Cancer Therapy
Similar activity, less toxic, more tolerable than cyclophosphamide, methotrexate, and fluorouracil
Tuesday, October 25, 2011

Vandetanib Ups Survival in Medullary Thyroid Carcinoma
Improved progression-free survival, disease control rate, objective and biochemical response
Tuesday, October 25, 2011

AACR: NSAID Use Tied to Lower Colorectal Cancer Mortality
At least 10 years of NSAID use significantly lowers CRC mortality in postmenopausal women
Tuesday, October 25, 2011

Pre-Op Regimen Tolerable for Esophageal Adenocarcinoma
But fails to meet objective of achieving pathologic complete response of 40 percent
Monday, October 24, 2011

First Versions of Generic Zyprexa Approved
To treat schizophrenia or bipolar disorder
Monday, October 24, 2011

CHEST: Study Looks at Sildenafil Dose for Youth With PAH
Medium doses seem to have best risk-benefit ratio for children with pulmonary artery hypertension
Monday, October 24, 2011

Immunotherapy-Chemo Combo Improves Survival in NSCLC
Addition of TG4010 to standard chemotherapy improves six month progression-free survival
Monday, October 24, 2011

LABA Use Ups Risk of Serious Asthma Events in Children
Concomitant use of inhaled corticosteroids, long acting β²-adrenergic receptor agonists may cut risk
Monday, October 24, 2011

Letrozole Monotherapy Shows Breast CA Long-Term Benefits
Sequential treatments with letrozole and tamoxifen have similar outcomes to letrozole monotherapy
Friday, October 21, 2011

Dopamine Polymorphisms Tied to Methylphenidate Response
Dopamine transporter and receptor polymorphisms associated with variability in dose-response
Friday, October 21, 2011

Tdap Vaccinations Recommended for Families With Newborns
Mothers and close family members should receive boosters
Thursday, October 20, 2011

Postnatal Steroids Mar Preterm Infant Cerebellar Growth
And, agonist of Shh-Smo pathway protects against steroid induced cerebellar injury in neonatal mice
Thursday, October 20, 2011

Intensive Lipid Therapy Lowers Plaque Lipid Content
Carotid plaque lipid content decreases significantly after one year of therapy, lasts in second year
Thursday, October 20, 2011

Drug-Eluting Stents With Abnormal ABI Tied to Mortality
Predictive of one-year all cause, cardiovascular mortality after drug-eluting stent implantation
Thursday, October 20, 2011

Early Initiation of ART After TB Treatment Ups Survival
Risk of death reduced for patients with a CD4+ T-cell count of less than 50 per cubic millimeter
Wednesday, October 19, 2011

Antidepressants Used by About 11 Percent of Americans
Use varies by sex, age, race and other variables
Wednesday, October 19, 2011

Adjuvant S-1 Improves Five-Year Outcomes in Gastric Cancer
Oral fluoropyrimidine derivative, S-1, improves overall, relapse-free survival at five years
Wednesday, October 19, 2011

ASRM: Etiology, Treatment of Hot Flushes Reviewed
Hot flushes likely related to changes in CNS neurotransmitters tied to estrogen withdrawal
Wednesday, October 19, 2011

Maternal ACE Inhibitor Use Not Tied to Congenital Defects
First trimester use of ACE inhibitors has a similar risk profile to use of other antihypertensives
Wednesday, October 19, 2011

Readmission Risk Models Display Poor Predictive Ability
Current hospital readmission risk models for comparative or clinical purposes perform poorly
Tuesday, October 18, 2011

Addition of Dulanermin Doesn't Improve Outcomes in NSCLC
Patients with advanced or recurrent non-small-cell lung cancer do not benefit from dulanermin
Tuesday, October 18, 2011

Topotecan Induction Feasible for High-Risk Neuroblastoma
No deaths or dose-limiting toxicities with dose-intensive topotecan, cyclophosphamide induction
Tuesday, October 18, 2011

ASA: Obesity Ups Peri-Op Peds Respiratory Complications
And, significantly lower effective dose of propofol causes loss of consciousness in obese children
Monday, October 17, 2011

Exercise Shows Potential for Migraine Prophylaxis
Reduction in migraine frequency similar for exercise, relaxation, and topiramate treatment
Monday, October 17, 2011

No Effect of Prophylaxis Type on Pulmonary Embolism Rate
Prophylaxis agent, anesthesia type do not affect pulmonary embolism rate post hip arthroplasty
Friday, October 14, 2011

Patients Remain Seizure-Free Long After Epilepsy Surgery
Seizure recurrence varies with the type of surgical treatment
Friday, October 14, 2011

Pediatric Asthma Drug Prescriptions on the Upswing
Costs associated with medications significantly up since late 1990s
Thursday, October 13, 2011

Vitamin D Dependent Pathway Key in Immunity Against TB
T cells release interferon-γ to induce antimicrobial activities by human macrophages
Thursday, October 13, 2011

Polytherapy With Valproate Ups Fetal Malformation Risk
Higher risk of malformation with carbamazepine, lamotrigine polytherapy with valproate
Wednesday, October 12, 2011

Flu Vaccine With Adjuvant MF59 Efficacious in Infants
Oil-in-water emulsion adjuvant vaccine has 75 percent relative efficacy versus non-adjuvant shot
Wednesday, October 12, 2011

Long-Term Vitamin E Use Increases Prostate Cancer Risk
Absolute increase in prostate cancer risk 1.6 per 1,000 person-years with long-term vitamin E
Wednesday, October 12, 2011

Financial Conflicts of Interest Prevalent, Under-Reported
Conflicts of interest prevalent; under-reported by members, chairs of panels developing guidelines
Wednesday, October 12, 2011

Prenatal Folic Acid Cuts Severe Language Delay in Offspring
Children of mothers taking prenatal folic acid have lower risk of severe language delay
Wednesday, October 12, 2011

Colon Inflammation Markers Lower With Ginger Extract
Significant decrease in mean percent change in two markers when normalized to free arachidonic acids
Tuesday, October 11, 2011

Leukemia Drug May Cause Pulmonary Arterial Hypertension
PAH seen in patients taking Sprycel
Tuesday, October 11, 2011

High Yield of Viral Diagnoses for RT-PCR in Respiratory Infection
But, rapid communication of RT-PCR results to clinicians has no benefit on patient care
Tuesday, October 11, 2011

Fludarabine, Alemtuzumab Combo Ups Survival in CLL
But combination therapy is associated with more adverse events than fludarabine monotherapy
Tuesday, October 11, 2011

Some Dietary Supplements Up Mortality Risk in Older Women
Several common vitamin, mineral supplements increase mortality risk; calcium lowers risk
Tuesday, October 11, 2011

Natalizumab Effective for Relapsing-Remitting MS
Treatment well-tolerated over two years, but adverse events reported more frequently after NTZ
Monday, October 10, 2011

High Chocolate Consumption Tied to Lower Risk of Stroke
Significantly reduced risk of stroke for women in the highest quartile of chocolate consumption
Monday, October 10, 2011

Septicemia Most Costly Reason for Hospitalization in 2009
Almost one in 23 patients had septicemia; average of 4,600 new patients treated each day
Monday, October 10, 2011

Improved Virologic Response After Triple Class Failure in HIV
Improvement in viral load suppression, decrease in rate of AIDS likely due to new meds
Monday, October 10, 2011

Upfront Zoledronic Acid Ups Bone Density in Breast Cancer
Increases bone mineral density in postmenopausal women receiving aromatase inhibitors
Monday, October 10, 2011

Juvisync Approved for Type 2 Diabetics With High Cholesterol
Previously approved meds combined in one tablet
Friday, October 07, 2011

Cialis Approved to Treat Benign Prostatic Hyperplasia
Also approved for treatment of BPH and erectile dysfunction occurring simultaneously
Friday, October 07, 2011

Infliximab Improves Clinical Outcome in Ulcerative Colitis
Early mucosal healing with infliximab improves long-term outcome, reduces need for colectomy
Friday, October 07, 2011

Anti-TNF-α Use Cuts Diabetes Risk in Rheumatoid Arthritis
Rheumatoid arthritis patients have a 51 percent reduced risk of diabetes with anti-TNF-α use
Friday, October 07, 2011

Use of Oral Steroids Linked to Vitamin D Deficiency
Steroid users have more than two-fold increased risk of vitamin D deficiency than steroid nonusers
Thursday, October 06, 2011

Nonanthracycline Trastuzumab Regimen Safe and Effective
Similar survival to AC-T plus trastuzumab; fewer acute toxic effects in HER2-positive breast cancer
Thursday, October 06, 2011

Prolonged Exposure, Cognitive Therapy Prevent Chronic PTSD
Prolonged exposure, cognitive therapy, delayed PE, but not escitalopram, placebo prevent chronic PTSD
Thursday, October 06, 2011

More Minority Patients in Low-Quality, High-Cost Hospitals
More elderly black, Hispanic, Medicaid patients consult worst rather than best hospitals
Thursday, October 06, 2011

Oral Acyclovir Improves Outcomes in Neonatal Herpes
Six-month acyclovir therapy improves neurodevelopment in infants with CNS involvement
Thursday, October 06, 2011

Oral Teriflunomide Effective in Relapsing Multiple Sclerosis
Oral teriflunomide significantly reduces relapse rates, disease progression, MRI disease evidence
Wednesday, October 05, 2011

Health Risks for Women Exposed to DES in Utero
Increased adverse outcomes for diethylstilbestrol-exposed women with vaginal epithelial changes
Wednesday, October 05, 2011

Feasible to Stop Post-Renal Transplant Anti-Rejection Meds
Lymphoid irradiation, donor stem cells eliminate immunosuppressant use post-renal transplant
Wednesday, October 05, 2011

High Children's Asthma Care Compliance in Peds Hospitals
But moderate compliance for post-discharge home-management plan of asthma care in children
Tuesday, October 04, 2011

Hormonal Contraceptives May Up HIV-1 Acquisition by Women
Also tied to increased risk of HIV-1 transmission from HIV-1 infected women to men
Tuesday, October 04, 2011

Prior DNA Priming Ups Influenza Vaccine Effectiveness
H5-DNA priming 24 weeks pre-H5N1 monovalent inactivated vaccine increases immune response
Tuesday, October 04, 2011

Flibanserin Effective Therapy for Hypoactive Sexual Desire
Superior for change in the number of sexual satisfying events, desire in premenopausal women
Monday, October 03, 2011

About One in 10 Parents Use Alternate Vaccination Schedule
Non-blacks, those without regular child health care provider use alternative schedule more
Monday, October 03, 2011

Activated Protein C Inhibitor Effective in Hemophilia A
Specific APC inhibitor PNASN-1 increases thrombin generation to near normal in FVIII deficiency
Friday, September 30, 2011

Aspirin Resistance Is Relatively Common Phenomenon
But poor compliance may contribute to substantial number of apparent resistance cases
Friday, September 30, 2011

Topiramate Effective in Post-Traumatic Stress Disorder
Re-experiencing symptoms, avoidance/numbing symptoms improve significantly with topiramate
Friday, September 30, 2011

Tamoxifen Use Tied to Diabetes Risk in Breast Cancer Survivors
But aromatase inhibitor use has no association with diabetes in older breast cancer survivors
Friday, September 30, 2011

Surfactants Feasible for Self-Breathing Preterm Infants
Decrease the need for mechanical ventilation in preterm infants breathing spontaneously on CPAP
Friday, September 30, 2011

SSRI With Antiplatelet Therapy Ups Post-MI Bleeding Risk
Selective serotonin reuptake inhibitors with ASA tied to higher bleeding risk than ASA alone
Thursday, September 29, 2011

Slow, Steady Rise in Stimulant Use for ADHD Since 1996
Adolescent use up, decrease in preschoolers, with variations in gender, geography, racial group
Thursday, September 29, 2011

DNA Repair Capacity IDs Non-Small-Cell Lung Cancer Survival
Worse overall and three-year survival for patients with high DNA repair capacity
Wednesday, September 28, 2011

Cytisine More Effective Than Placebo for Smoking Cessation
Higher 12-month abstinence rate with cytisine; cheaper than other pharmacotherapies
Wednesday, September 28, 2011

Increasing Dose of Saw Palmetto No Better Than Placebo in BPH
Results comparable to placebo in benign prostatic hyperplasia-related urinary tract symptoms
Wednesday, September 28, 2011

Calcineurin-Inhibitor-Sparing Regimens Improve Outcomes
Use of calcineurin-inhibitor-sparing regimens immediately after kidney transplant ups outcomes
Wednesday, September 28, 2011

DMARDs Found to Be Effective Treatment for Juvenile Arthritis
But more research is needed to define long-term safety
Wednesday, September 28, 2011

Cognition Similar for Standard, Intensive Glycemic Control
Total brain volume, mortality risk higher with intensive glycemic lowering for type 2 diabetes
Wednesday, September 28, 2011

Quadrivalent HPV Vaccine More Cost-Effective Than Bivalent
Bivalent vaccine should be about £19 to £35 cheaper to be as cost-effective as quadrivalent
Wednesday, September 28, 2011

Benefits, Harms With Off-Label Atypical Antipsychotic Use
Adverse events common; favorable response varies with drug and off-label condition being treated
Tuesday, September 27, 2011

Cell of Origin Key in Relapsed B-Cell Lymphoma Prognosis
Better response in germinal center B-like diffuse large B-cell lymphoma with R-DHAP therapy
Tuesday, September 27, 2011

ESR1 Expression Predicts Tamoxifen Benefit in Breast CA
Lower expression of ESR1 determines tamoxifen resistance in ER-positive breast tumors
Tuesday, September 27, 2011

Asthma Prevalence Elevated in Youth With Diabetes
Asthma associated with poor glycemic control in youth with type 1 diabetes, especially if untreated
Tuesday, September 27, 2011

Remicade Approved for Ulcerative Colitis in Children
Aged six and older
Monday, September 26, 2011

Tdap Safe After Tetanus-, Diphtheria-Containing Products
Children age 7 to 10 susceptible to pertussis and under-immunized should receive single Tdap dose
Monday, September 26, 2011

Updated Guides Compare Treatments for GERD
Both drug therapies and surgeries considered effective
Monday, September 26, 2011

Evidence for Nondrug Childhood Constipation Therapies Limited
Some evidence for effectiveness of fibers, but not for fluids, biotics, behavioral therapy
Monday, September 26, 2011

GLCCI1 SNP Lowers Response to Inhaled Steroids in Asthma
rs37973 single neucleotide polymorphism tied to decreased inhaled glucocorticoid response
Monday, September 26, 2011

Adjuvant Zoledronic Acid Not Beneficial in Breast Cancer
Disease-free, overall survival in early-stage breast cancer not improved by zoledronic acid
Monday, September 26, 2011

Generic Tacrolimus Safe for Liver, Kidney Recipients
No change in liver, kidney function; no rejection seen after substitution for reference product
Monday, September 26, 2011

Glucagon-Like Peptide-1 Therapy Ups Pancreatitis Risk
Exenatide, sitagliptin up odds ratio of pancreatitis, increase reports of pancreatic cancers
Friday, September 23, 2011

FDA Expands Age Indication for Boostrix
The vaccine is now licensed for use in people 65 and older
Thursday, September 22, 2011

Rotavirus Vaccine Introduction Cut Health Care Use, Costs
National estimated reduction of 64,855 hospitalizations and $278 million in 2007 to 2009
Wednesday, September 21, 2011

F1+2, VEGF, D-Dimer Levels Up in Nonallergic Asthma
Patients exhibit autoreactivity, increased coagulation levels and angiogenesis markers
Wednesday, September 21, 2011

2006/2007 U.S. Flu Vaccination Policy Lowers Morbidity
Expansion of vaccination policy to include healthy children cuts influenza morbidity by 34 percent
Wednesday, September 21, 2011

Mortality Up in Hospitals With More Minority Trauma Patients
Trauma patients' odds of mortality linked to the proportion of minority patients in the hospital
Wednesday, September 21, 2011

Age, Treating Physician Tied to Pediatric Psoriasis Treatment
Dermatologists, internists prescribe high-potency steroids; pediatricians prescribe topical tacrolimus
Wednesday, September 21, 2011

Cognitive Behavior Therapy, SRIs Improve OCD Treatment
Better response in pediatric obsessive compulsive disorder than medication management alone
Tuesday, September 20, 2011

Payer Status Affects Health Care Quality and Outcomes
Heart failure patients without private insurance/HMO have poorer care, worse outcomes
Tuesday, September 20, 2011

Lower Sudden Death Risk With Add-On Antiepileptic Therapy
Treatment tied to reduction of sudden death incidence in patients with refractory epilepsy
Tuesday, September 20, 2011

Tasquinimod Ups Castration-Resistant Prostate CA Survival
Delays disease progression, ups progression-free survival with acceptable adverse event profile
Tuesday, September 20, 2011

Mycophenolate Mofetil Safe, Effective for Refractory Lupus
MMF, standard therapy tolerated for antimalarial-resistant cutaneous lupus erythematosus
Tuesday, September 20, 2011

Enoxaparin Bests Unfractionated Heparin in Occlusive PAD
Enoxaparin performs better than unfractionated heparin in peripheral arterial occlusive disease
Monday, September 19, 2011

Fluoroquinolones Up Risk of Post-Biopsy Acute Prostatitis
Isolated gram-negative bacteria were fluoroquinolone-resistant in 85.7 percent of cultures
Friday, September 16, 2011

Child Self-Exposure to Meds Explains Most Drug Poisoning
Child self-exposure accounts for 95 percent of emergency visits from 2001 to 2008 in U.S.
Friday, September 16, 2011

CDC: MRSA USA300 Strain Resistant to Topical Antibiotics
Most MRSA isolates susceptible to bacitracin, but USA300 isolates resistant to bacitracin, neomycin
Friday, September 16, 2011

Statins After Ischemic Stroke Not Tied to Brain Hemorrhage
Similar lack of association found for subgroups and dose-response analyses
Friday, September 16, 2011

CDC: Risk Factors ID'd in Most C. difficile Diarrhea Cases
Traditional risk factors, including antimicrobial use, hospitalization, account for majority of cases
Thursday, September 15, 2011

AACR: Genetic Data ID Breast Cancer Progression Pathways
Identification of pathways, driver genes leads to novel targeted therapy for breast cancer
Thursday, September 15, 2011

CDC: Recent Influenza Activity Relatively Low
Annual vaccinations still needed to prevent flu and complications
Thursday, September 15, 2011

Anti-Nausea Drug May Lead to Dangerous Heart Rhythms
FDA alerts public to ongoing safety review for Zofran
Thursday, September 15, 2011

Specific Pain Reduction Seen With Transdermal Buprenorphine
Buprenorphine, but not fentanyl, significantly reduces bone pain and primary hyperalgesia
Thursday, September 15, 2011

Long-Term Nonaspirin NSAID Use Ups Renal Cell Cancer Risk
Nonsteroidal anti-inflammatory drugs, but not aspirin or acetaminophen, increase RCC risk
Wednesday, September 14, 2011

Reduced Treatment Time Noninferior for Some With Hep C
Hepatitis C virologic response similar with peginterferon-ribavirin for 24 versus 48 weeks
Wednesday, September 14, 2011

No Benefit of Long-Term Azithromycin for Rhinosinusitis
Low weekly dose of 500 mg for 11 weeks provides no benefit over placebo in chronic rhinosinusitis
Wednesday, September 14, 2011

Erectile Dysfunction Ups Risk of Cardiovascular Disease
Increased risk of cardiovascular disease, coronary heart disease, stroke, all-cause mortality
Wednesday, September 14, 2011

Sorafenib Plus DEB-TACE Safe, Tolerated in Unresectable HCC
Adverse events for transarterial chemoembolization with doxorubicin-eluting beads, sorafenib mostly mild
Wednesday, September 14, 2011

Many Mistakenly Believe FDA OKs Only Safe, Effective Drugs
Consumer explanations about safety, efficacy of drugs help public make better decisions
Wednesday, September 14, 2011

Venlafaxine, Clonidine Reduce Hot Flashes in Breast Cancer
Immediate reduction in hot flash scores with venlafaxine; lower week 12 scores with clonidine
Tuesday, September 13, 2011

Dalcetrapib Use Safe, Possibly Beneficial in Atherosclerosis
Dalcetrapib use reduces change in total vessel area, most-diseased segment over 24 months
Tuesday, September 13, 2011

Insulin Therapy May Slow Alzheimer's Progression
Pilot study shows intranasal delivery of the agent to be beneficial
Tuesday, September 13, 2011

TNF Inhibitors for RA Do Not Increase Malignancy Risk
But tumor necrosis factor inhibitor exposure ups non-melanoma skin cancer and melanoma risk
Monday, September 12, 2011

Clopidogrel Adherence Tied to Daily Pre-PCI Med Adherence
Low adherence also tied to cost; physician, pharmacy access; patient-provider communication
Monday, September 12, 2011

Opioid Delivery to Olfactory Region Ups Therapeutic Effects
More of drug delivered to central nervous system, no increase in plasma drug exposure in rats
Friday, September 09, 2011

Oxycodone No Safer Than Codeine During Breastfeeding
One in five breastfed infants exposed to oxycodone has central nervous system depression
Friday, September 09, 2011

SAMHSA Assesses Recent Trends in Illicit Drug Use
Illicit drugs and alcohol use in 2010 similar to that in 2009, but higher than in 2008
Thursday, September 08, 2011

Comparative Efficacy Proposed for European Drug Approval
Superiority, equivalence, inferiority of new drugs should be compared with existing therapies
Wednesday, September 07, 2011

Many Hospital Staff Uniforms Contaminated With Bacteria
More than 60 percent of uniforms are contaminated, with similar rates between nurses, physicians
Wednesday, September 07, 2011

Gestational NSAID Intake Tied to Spontaneous Abortion Risk
Risk increases with any type, dosage of nonaspirin NSAIDs separately or in combination
Wednesday, September 07, 2011

Hospitalized Children Exposed to Considerable Polypharmacy
Pediatric patients with rare conditions have significantly greater likelihood of polypharmacy
Tuesday, September 06, 2011

Immunoadsorption Therapy Effective in E. coli-Induced HUS
Immunoadsorption effective, safe for neurological complications of hemolytic uremic syndrome
Tuesday, September 06, 2011

Vaccine Rates Increase Among Children Aged 11 to 12 Years
However, often not all of the recommended vaccines are administered during vaccination visits
Tuesday, September 06, 2011

Temp Staff Errors More Harmful Than Those of Permanent Staff
Medication errors by temporary staff more likely to be life-threatening or harmful
Monday, September 05, 2011

FDA: Antipsychotic Drug May Cause Severe Allergic Reaction
FDA advises of updated label for Saphris reflecting risk
Friday, September 02, 2011

Antibiotic Prescriptions Down for Pediatric Patients
But the drugs continue to be overprescribed for those aged 14 and under
Friday, September 02, 2011

Pediatric Vaccination Rates High in United States
Still room for improvement in under-vaccinated populations
Thursday, September 01, 2011

Success With Valproic Acid for Glioblastoma With TMZ Therapy
Valproic acid better than enzyme-inducing drugs for patients with glioblastoma needing antiepileptic
Thursday, September 01, 2011

Four Categories of Eligibility for Contraceptive Use Endorsed
ACOG endorse use of 2010 U.S. Medical Eligibility Criteria for Contraceptive Use
Tuesday, August 30, 2011

AAP Recommends Quadrivalent MMRV for Most Children
But separate MMR, varicella vaccines indicated for children with personal/family history of seizures
Tuesday, August 30, 2011

Drug-Eluting Stents Better for Saphenous Vein Graft Lesions
Better clinical, angiographic outcomes with drug-eluting versus bare-metal stents one year later
Monday, August 29, 2011

ESC: Preventive Drug Use Tied to Country's Economic Status
Preventive drug use in cardiovascular disease varies with country's economic status
Monday, August 29, 2011

Apixaban Superior to Warfarin for Stroke Prevention in A-Fib
Apixaban reduces stroke risk, embolism, bleeding, and mortality in patients with atrial fibrillation
Monday, August 29, 2011

Colchicine Safe, Effective Adjunct in Recurrent Pericarditis
Data reveals drug safe and effective for secondary prevention of recurrent pericarditis
Monday, August 29, 2011

Loss of Jobs Means Loss of Health Coverage for Many in U.S.
Majority report delay in getting needed healthcare and financial difficulties paying medical bills
Monday, August 29, 2011

IOM: Few Health Issues Caused By Vaccines
Report should alleviate parental fears regarding vaccination of their children
Friday, August 26, 2011

Extended-Release Opioid Pain Medication Approved
Nucynta ER sanctioned for chronic pain in adults
Friday, August 26, 2011

Expedited Partner Therapy Use Benefits Gonorrhea, Chlamydia
In states where expedited partner therapy is not legal, practitioners should advocate for legality
Friday, August 26, 2011

Complementary Medicine Used More by Health Care Workers
U.S. health care providers use complementary, alternative medicine more than support workers
Friday, August 26, 2011

Pharmaceutical Ads Often Don't Adhere to U.S. FDA Guidelines
Only 18.1 percent of advertisements fully adhere to FDA guidelines, over half do not quantify serious risks
Thursday, August 25, 2011

CDC: HPV Vaccine Rates Lag Behind Other Teen Vaccines
Report reveals vaccine coverage increased from 2009 to 2010 among adolescents aged 13-17 years
Thursday, August 25, 2011

Firazyr Approved for Acute Hereditary Angioedema
Most common side effects: injection site reactions, fever, increase in liver enzymes, dizziness, rash
Thursday, August 25, 2011

Azithromycin Decreases COPD Exacerbation Frequency
Daily azithromycin for one year reduces COPD exacerbations in selected patients
Wednesday, August 24, 2011

Botox Approved to Treat Urinary Incontinence
For use among people with certain neurologic conditions
Wednesday, August 24, 2011

Hospitalization Ups Unintentional Discontinuation of Meds
Discontinuation of medications higher in patients with ICU admissions than in non-ICU admissions
Tuesday, August 23, 2011

NSAID Intolerance Indicative of Intolerance to Etoricoxib
Patients with urticaria or angioedema reactions to NSAIDs may also be intolerant to etoricoxib
Monday, August 22, 2011

Similar Platelet Response With 50 or 100 mg Dose of Aspirin
No difference in platelet response, cardiovascular events with 50 or 100 mg aspirin for five years
Monday, August 22, 2011

Methotrexate Lowers Response to Pneumococcal Vaccine
In patients with arthritis, methotrexate reduces antibody response after pneumococcal vaccination
Monday, August 22, 2011

CDC: 2010/2011 Flu Vaccination Coverage Studied
Coverage in health care personnel and pregnant women remained stable versus previous season
Thursday, August 18, 2011

CDC: Flu Vaccine Recommendations Unchanged
Flu vaccine recommended in those ≥6 months; strains same as previous season
Thursday, August 18, 2011

Chinese Herbal Decoction Cuts Time to H1N1 Fever Resolution
Maxingshigan-yinqiaosan effective alone and in combination with oseltamivir
Tuesday, August 16, 2011

Evidence Lacking That Aspirin Use in IVF Improves Birth Rate
Lack of evidence for effect of aspirin on clinical pregnancy, ectopic, and miscarriage rates
Thursday, August 11, 2011

More Neurology Residents Comfortable Using tPA for Stroke
Residents' experience, comfort using tPA to treat acute ischemic stroke increased from 2000 to 2010
Monday, August 08, 2011

Cost of Interacting With Payers Higher in U.S. Than Canada
U.S. physicians and nursing staff spend more time and money interacting with health plans
Friday, August 05, 2011

Antidepressant Prescriptions for Non-Psych Disorders Up
Non-psychiatrists' antidepressant prescriptions without psych diagnosis rise from 1996 to 2007
Friday, August 05, 2011

CDC: Age Range Expanded for Meningococcal Vaccine
Report reveals that two licensed meningococcal conjugate vaccines likely interchangeable
Thursday, August 04, 2011

Teens Who Misuse Controlled Meds More Likely to Abuse Drugs
Among teens who take controlled meds, 22 percent report misuse, including intentionally getting high
Thursday, August 04, 2011

FDA: High-Dose Fluconazole Tied to Birth Defects
Chronic use during first trimester may lead to rare and distinct set of birth defects
Wednesday, August 03, 2011

High Doses of Zinc Found to Reduce Common Cold Duration
Daily use of lozenges with more than 75 mg zinc acetate reduces cold duration by 42 percent
Wednesday, August 03, 2011

High Risk of Adverse Outcomes Tied to SSRI Use in Elderly
Increased risk with selective serotonin reuptake inhibitors, other drugs than tricyclic antidepressants
Wednesday, August 03, 2011

Risperidone Not Effective for Military-Related PTSD
Side effects occur without reduction in posttraumatic stress disorder symptoms in veterans
Tuesday, August 02, 2011

Lower Risk of Repeat Vascular Events in Young Adults on Statins
Young adults with ischemic stroke of undetermined etiology benefit from statin therapy
Tuesday, August 02, 2011

DHA Intake in Pregnancy Tied to Fewer Colds in Infants
Maternal intake of docosahexaenoic acid during pregnancy reduces some illness symptoms in infants
Monday, August 01, 2011

Low-Molecular-Weight Heparin Better for Primary PCI
Compared to unfractionated heparin, reduced mortality and bleeding for patients with STEMI
Friday, July 29, 2011

Apixaban Ups Bleeding Without Reducing Ischemic Events
Trial evaluating addition of apixaban to antiplatelet therapy terminated prematurely
Tuesday, July 26, 2011

Propranolol Safe and Effective for Infantile Hemangiomas
Volume, color, and elevation of infantile hemagiomas improve with propranolol treatment
Tuesday, July 26, 2011

FDA: Chantix Tied to Slight Risk of Cardiac Events
Patients with cardiovascular disease may have higher risk of certain cardiac events
Monday, July 25, 2011

High Mortality Decline With One-Dose Varicella Vaccine
Implementation of one-dose vaccination program reduces overall varicella mortality by 88 percent
Monday, July 25, 2011

Pagibaximab Seems Safe, Well Tolerated in High-Risk Neonates
Three once-a-week infusions of pagibaximab tied to staphylococcal sepsis prevention
Monday, July 25, 2011

FDA: Dronedarone Tied to Cardiovascular Events, Death
PALLAS study stopped due to higher risk of cardiovascular events and deaths in those taking drug
Friday, July 22, 2011

Stopping Low Dose Aspirin Ups Cardiac Risk
Patients with a history of heart disease who stop taking aspirin are at higher risk of heart attack
Wednesday, July 20, 2011

FDA Approves Vaccine for 2011/2012 Influenza Season
Formulation will be used by the six manufacturers licensed to manufacture, distribute in U.S.
Tuesday, July 19, 2011

Antidepressants Found Lacking for Seniors With Dementia
Research findings suggest rethinking prescription practices for these patients
Tuesday, July 19, 2011

Low Health Literacy Linked to Poorer Health Outcomes
Limited health literacy correlated with more hospitalizations and higher use of emergency care
Tuesday, July 19, 2011

cART Ups Life Expectancy in Ugandan HIV Patients
Ugandan women receiving combo antiretroviral therapy have lower mortality rate than men
Tuesday, July 19, 2011

IAS: Early Antiretroviral Therapy Reduces HIV Transmission
Early initiation of therapy reduces transmission to HIV-1 negative partner, clinical end points
Tuesday, July 19, 2011

Statin Therapy Does Not Up Cancer Risk in Older Adults
Propensity matching showed no significantly increased cancer risk linked to statin therapy
Monday, July 18, 2011

Factor VIII Dose Should Consider Both Body Weight and Fat Mass
For those with hemophilia A, dose calculation should be individually adapted to under-/overweight patients
Monday, July 18, 2011

Safety Concern for Chronic NSAID Users With HTN, CAD
Chronic NSAID use tied to increased risk of all-cause death, myocardial infarction, stroke
Monday, July 18, 2011

Faster Insulin Action With Needle-Free Jet Injection
Jet injection administration improves pharmacokinetic, pharmacodynamic insulin profile
Friday, July 15, 2011

Clopidogrel, PPIs Linked to MI Risk After PCI
Combined clopidogrel and PPI use doubles MI rates after percutaneous coronary intervention
Friday, July 15, 2011

Vaccination Rates Up for Those With Liver Disease, Diabetes
Hep A, B vaccinations increase but still low in patients with chronic liver disease, diabetes
Friday, July 15, 2011

H1N1 2009 Vaccine Not Tied to Guillain Barré Syndrome Risk
Adjuvanted pandemic influenza A 2009 vaccine does not increase Guillain Barré syndrome risk
Thursday, July 14, 2011

Albuterol Not Better Than Placebo in Self-Report Outcomes
FEV1 improves but self-reported outcomes not significantly better than placebo, sham acupuncture
Wednesday, July 13, 2011

Antiretroviral Drugs May Halt HIV Spread in Heterosexuals
Studies find that daily use may prevent HIV acquisition in unaffected heterosexuals
Wednesday, July 13, 2011

Similar Thyroid Risk for Brand-Name, Generic Amiodarone
Incidence of thyroid dysfunction rates similar in patients treated with either formulation
Tuesday, July 12, 2011

Early Metformin Therapy Prevents, Delays PCOS in Girls
Girls with low birth weight and precocious puberty have improved outcomes with early metformin
Monday, July 11, 2011

Combination Therapy for A-Fib Increases Bleeding Risk
Increase seen in clinically relevant and major bleeding events, no reduction in stroke risk
Friday, July 08, 2011

Metformin/Rosiglitazone Tied to Early Decrease in Diabetes
But subsequent deterioration in insulin resistance and β-cell function similar to placebo
Friday, July 08, 2011

H1N1, Seasonal Flu Vaccines From 2009 to 2010 Were Safe
Seasonality likely contributed to Bell's palsy signal following monovalent inactivated vaccine
Friday, July 08, 2011

Drug Susceptibility in Gonorrhea May Be Declining
Minimum inhibitory concentrations to cephalosporins up; still effective treatment
Thursday, July 07, 2011

Postpartum Contraceptive Use Guidelines Updated
Combined hormonal contraceptives should not be used during first 21 days after delivery
Thursday, July 07, 2011

NSAIDs, COX-2 Inhibitors Tied to Increased Risk of A-Fib
Association strongest for new users, with a higher risk for COX-2 inhibitors than NSAIDs
Thursday, July 07, 2011

New Regimens Equal to Standard Isoniazid for Adults With HIV
Second study shows no TB-free survival benefit from isoniazid prophylaxis in HIV+/− infants
Wednesday, July 06, 2011

Nesiritide Has Small, Nonsignificant Effect on Dyspnea
Nesiritide use not linked to changes in rate of deaths or rehospitalization
Wednesday, July 06, 2011

First Trimester Antidepressant Use Tied to Childhood ASD
Prenatal selective serotonin reuptake inhibitors use associated with autism spectrum disorders
Tuesday, July 05, 2011

Lopinavir-Ritonavir Treatment Tied to Adrenal Dysfunction
In utero LR exposure increases risk of transient adrenal dysfunction with postnatal LR treatment
Tuesday, July 05, 2011

Increased First-Trimester Prescription Drug Use in U.S.
By 2008, roughly 50 percent of pregnant women report taking at least one medication
Tuesday, July 05, 2011

Varenicline Use Linked to Adverse Cardiovascular Events
Increased risk of serious adverse cardiovascular events with varenicline use for tobacco users
Tuesday, July 05, 2011

Aspirin As Primary Prevention Strategy Investigated
No significant reduction in risk of stroke, mortality, or total coronary heart disease
Friday, July 01, 2011

Vitamin D Supplementation Safe and Effective in Pregnancy
Desirable circulatory levels of vitamin D safely attained by pregnant women and their neonates
Friday, July 01, 2011

Around One in 10 Computerized Prescriptions Contains Errors
Most common error is omitted information; one third of errors are potential adverse drug events
Friday, July 01, 2011

Pain Is a Public Health Issue and Economic Burden in U.S.
Integrated approach and research needed to treat, manage, and prevent chronic pain
Thursday, June 30, 2011

Bottles of Tylenol Recalled
Product being recalled due to uncharacteristic odor
Thursday, June 30, 2011

Flu Vaccine Safe for Sunitinib, Sorafenib Treated Patients
Seroprotective rate for cancer patients treated with sunitinib or sorafenib similar to controls
Tuesday, June 28, 2011

ADA: Diabetes Prevention Strategies Are Cost-Effective
Lifestyle intervention and metformin treatment are cost-effective and improve quality of life
Tuesday, June 28, 2011

Prophylactic Heparin May Not Prevent Placental Insufficiency
Unfractionated heparin offers no advantage to standard care for risk of placental insufficiency
Monday, June 27, 2011

ADA: Sulphonylurea Agents May Increase Cardiac Events
Sulfonylurea therapies may increase risk of CVD events in older patients with type 2 diabetes
Monday, June 27, 2011

Higher Antibiotic Use Among Younger Home Care Patients
Those younger than 65 years and with poor health more likely to receive antibiotics
Thursday, June 23, 2011

Early Statin Therapy May Reduce Unstable Angina
Risk of death, heart attack, or stroke is not reduced by statins after acute coronary syndromes
Tuesday, June 21, 2011

Long-Acting Reversible Contraceptives Safe for Most
Despite benefits, most women use other methods due to lack of knowledge and cost concerns
Tuesday, June 21, 2011

Millions in U.S. Do Not Receive PAD Prevention Therapies
Treatment of peripheral artery disease with multiple agents tied to reduced all-cause mortality
Tuesday, June 21, 2011

HPV Vaccination Program Tied to Fewer Cervical Abnormalities
Decrease in incidence of high-grade cervical lesions in girls younger than 18 years
Friday, June 17, 2011

SVS: HRT May Reduce Risk of Peripheral Arterial Disease
Significant reduction also seen for postmenopausal women with atherosclerosis risk factors
Friday, June 17, 2011

FDA: Smoking Cessation Drug Tied to Cardiac Issues
Varenicline (Chantix) associated with small but increased risk of cardiac problems
Friday, June 17, 2011

New Meningococcal A Conjugate Vaccine Is Effective
New vaccine elicits stronger group A antibody response than polysaccharide reference vaccine
Wednesday, June 15, 2011

New Rotavirus Vaccine Reduces Cases of Infant Diarrhea
Moderately increased risk of intussusception following RV1 vaccination
Wednesday, June 15, 2011

Life Expectancy in U.S. Counties Below Many Nations
Women, and black men and women have lower life expectancy in all U.S. counties
Wednesday, June 15, 2011

Inappropriate Medicines Tied to Serious Avoidable Adverse Events
Potentially and actually inappropriate medications are often prescribed in the ICU
Wednesday, June 15, 2011

Most Parents Vaccinate Their Children Despite Concerns
Vaccine safety information comes from health care providers, media, Internet, friends, family
Thursday, June 09, 2011

NSAID Use Linked to Increased Venous Thromboembolism Risk
Increased risks for VTE, unprovoked VTE, deep venous thrombosis, and pulmonary embolism
Wednesday, June 08, 2011

Antiepileptic Drugs Have Dose-Dependent Tie to Birth Defects
Drugs at start of pregnancy linked to increased risk of birth defects, especially at higher dose
Tuesday, June 07, 2011

Paroxetine With Pravastatin Raises Blood Glucose Levels
Combination causes considerable increase in blood glucose levels in patients with diabetes
Monday, June 06, 2011

More Strokes Treated With Thrombolytics in the U.S.
Use of thrombolytics for stroke treatment approximately doubled between 2005 and 2009
Friday, June 03, 2011

Fibroblast Growth Factor Not Effective in Limb Ischemia
Non-viral 1 fibroblast growth factor does not reduce amputation or death risk in limb ischemia
Wednesday, June 01, 2011

Corticosteroids May Shorten Pneumonia Hospital Stay
Dexamethasone therapy may reduce hospital stay in patients with community-acquired pneumonia
Wednesday, June 01, 2011

Maternal Influenza Vaccination Tied to Reduced Prematurity
Vaccination during pregnancy may reduce odds of prematurity in periods of influenza activity
Wednesday, June 01, 2011

Effect Estimates May Be Inflated in Biomarker Studies
Highly cited studies overestimate biomarker effect compared to meta-analyses
Tuesday, May 31, 2011

Dificid Approved to Treat C. diff Diarrhea
Recommended dosage is two times daily for 10 days
Tuesday, May 31, 2011

Acetaminophen Prescriptions for Children Often Incorrect
Excessive doses often prescribed for infants; underdosing common for 6- to 12-year olds
Friday, May 27, 2011

Polypills May Reduce Blood Pressure and LDL Cholesterol
Considerable side effects observed, but most are mild and do not warrant therapy cessation
Thursday, May 26, 2011

Lupus Factors Tied to Weak Response to Influenza Vaccine
Ethnicity, prednisone treatment, increased disease flares linked to low antibody response
Thursday, May 26, 2011

More Psychiatrists Believe in Clinical Value of Placebos
More than 60 percent of psychiatrists agree that placebos have therapeutic effects
Wednesday, May 25, 2011

Contact With Drug Industry Linked to Positive Attitudes
Substantial proportion of medical students believe gifts from drug industry affect prescribing
Wednesday, May 25, 2011

Heart-Friendly Fatty Acids Linked to Prostate Cancer
Omega-3, but not trans-fatty acids, associated with increased high-grade prostate cancer risk
Tuesday, May 24, 2011

Use of CCTA Screening Tied to Increased Invasive Testing
Coronary computed tomographic angiography tied to elevated medication use and revascularizations
Tuesday, May 24, 2011

Excess Medical Costs Tied to Diabetes in Youth Substantial
True especially for insulin-treated disease; much of excess costs are for prescription drugs
Monday, May 23, 2011

End-of-Life Cancer Care Differs in the U.S. and Canada
Rates of chemotherapy use are higher, but fewer hospitalizations in U.S. patients
Monday, May 23, 2011

Inappropriate Antibiotic Prescribing Common in Asthma
Co-dispensing of antibiotics and asthma drugs among children found to be very common
Monday, May 23, 2011

FDA: SimplyThick Should Not Be Used in Premature Infants
Product possibly linked to necrotizing enterocolitis in some infants
Monday, May 23, 2011

L-Arginine Linked to Decreased Pre-Eclampsia Risk
Supplementation with L-arginine and antioxidants decreases the risk for high-risk women
Friday, May 20, 2011

No Skin Atrophy With Long-Term Topical Corticosteroids
Long-term use of topical corticosteroids is a safe option for children with dermatitis
Friday, May 20, 2011

Lower HIV-Related Mortality, Increased Treatment in China
But injecting drug users and sexually infected have increased mortality, less treatment coverage
Thursday, May 19, 2011

AUA: Human Papillomavirus Prevalent in Male Foreskin
Researchers recommend vaccinating pre-adolescent boys against HPV
Wednesday, May 18, 2011

Propranolol Effectively Treats Infantile Hemangiomas
Also effective in treating recurrences of head and neck hemangiomas
Wednesday, May 18, 2011

Triamcinolone Ineffective in Eustachian Tube Dysfunction
Intranasal triamcinolone acetonide and placebo show comparable effect on tympanometric symptoms
Wednesday, May 18, 2011

Major Birth Defects Not Linked to Newer Antiepileptic Drugs
Use of newer antiepileptic drugs in first trimester not correlated with increased birth defect risk
Tuesday, May 17, 2011

ATS: Many Parents of Children With Asthma Avoid Flu Vaccine
Parents reluctant to vaccinate kids due to safety concerns and not seeing flu as asthma trigger
Tuesday, May 17, 2011

Heart Disease Risk Similar in Children Treated for ADHD
Attention-deficit/hyperactivity disorder drugs not associated with cardiovascular events
Tuesday, May 17, 2011

MRKAd5 Vaccine Found Ineffective Against HIV-1
Failed to protect against virus acquisition, decrease in viral load in South African study
Monday, May 16, 2011

Early HIV Therapy Reduces Partner's Infection Risk
Study findings released early after antiretroviral combo substantially lowers risk
Friday, May 13, 2011

Hydroxycarbamide Effective for Infant Sickle-Cell Anemia
Treatment may reduce pain and dactylitis, increase hemoglobin and fetal hemoglobin levels
Friday, May 13, 2011

Blacks Screened More Often Than Whites for Opioid Misuse
More regular office visits and restricted early refills for black patients treated with opioids
Thursday, May 12, 2011

Proton Pump Inhibitors May Increase Fracture Risk
Use of histamine 2 receptor antagonists not significantly associated with fracture risk
Wednesday, May 11, 2011

Exogenous Estrogen Use Linked to Cerebral Aneurysms
Lower rate of oral contraceptive use or hormone replacement therapy tied to cerebral aneurysm
Wednesday, May 11, 2011

Medical Education Participants Recognize Funding Bias
Yet most are unwilling to pay more for continuing medical education registration to overcome bias
Wednesday, May 11, 2011

Optimal Medical Therapy Often Not Applied Before PCI
Less than half of stable angina patients receive OMT before percutaneous coronary intervention
Tuesday, May 10, 2011

NSAIDs May Increase Cardio Risk in MI Patients
In patients with MI, NSAIDs may increase the risk of MI, death during the course of treatment
Tuesday, May 10, 2011

Residual Depressive Symptoms in Responders to Citalopram
Depressed patients who respond to citalopram but don't remit report residual depressive symptoms
Monday, May 09, 2011

NSAIDs, Aspirin May Increase Risk of Diverticulitis
Regular usage linked to higher risk of diverticulitis and diverticular bleeding in men
Monday, May 09, 2011

Icons May Help Adults Identify Acetaminophen Medicines
Consumers prefer explicit safety warnings, maximum dose information for acetaminophen
Friday, May 06, 2011

Infant Acetaminophen Drugs to Be Discontinued
Makers to end production of infant-drop versions to avoid confusion that may lead to overdose
Thursday, May 05, 2011

Bisphosphonates Tied to Small Risk of Atypical Fractures
Despite high prevalence of drug use in patients with atypical fractures, absolute risk is small
Wednesday, May 04, 2011

Leukotriene-Receptor Antagonist Effective in Asthma
May be equivalent to inhaled glucocorticoid, long-acting beta2-agonist
Wednesday, May 04, 2011

Individualized Guidelines May Improve Quality of Care
Calculating risk reduction expected from treatment based on characteristics may reduce costs
Wednesday, May 04, 2011

Lot of Warfarin Tablets Recalled
One tablet found to have more active ingredient than expected
Wednesday, May 04, 2011

CDC: Asthma Prevalence on the Rise in United States
Prevalence of the disease increased by 12.3 percent between 2001 and 2009
Tuesday, May 03, 2011

Nearly One in 10 Infants Given Supplements and Teas
Maternal herbal use, longer breast-feeding, and being Hispanic linked with use of teas
Tuesday, May 03, 2011

Tradjenta Approved for Type 2 Diabetes
Should not be used by type 1 diabetes patients
Monday, May 02, 2011

PAS: Pharmacies Often Give Infants Overdose Amounts
Infants, toddlers routinely receive higher amounts of prescription drugs than they should
Monday, May 02, 2011

Fractures Seen in Older Levothyroxine Users
Researchers find dose-response relationship in those aged 70 or older taking the drug
Friday, April 29, 2011

Flu Vaccination Safe for Post-Transplant Patients
Vaccination in the year after renal transplant linked to reduced risk of allograft loss, death
Thursday, April 28, 2011

Monthly Injection Effective for Opioid Dependence
Naltrexone superior to placebo in improving abstinence, retention, and relapse rates
Thursday, April 28, 2011

Anti-Inflammatory Drugs May Lower Antidepressant Efficacy
In mice, humans, anti-inflammatories attenuate effects of selective serotonin reuptake inhibitors
Wednesday, April 27, 2011

Vitamin E and Metformin Don't Improve Pediatric NAFLD
No reduction in alanine aminotransferase levels with vitamin E or metformin treatment
Wednesday, April 27, 2011

More MI Treatments Tied to Decreased Mortality in Sweden
Patients with STEMI have reduced mortality linked to increased use of evidence-based treatments
Tuesday, April 26, 2011

Epilepsy Drug Nonadherence Tied to Socioeconomic Status
Higher nonadherence in newly diagnosed children of low socioeconomic status
Tuesday, April 26, 2011

Black Cancer Patients More Willing to Pay to Extend Life
Minority patients more willing than whites to expend their financial resources to prolong life
Tuesday, April 26, 2011

ACC/AHA Issue Blood Pressure Control Guidelines for Elderly
Aim is to help practitioners control hypertension in older adults and reduce risks for it
Tuesday, April 26, 2011

Diabetes Patients Benefit From Amlodipine Titration
Patients with type 2 diabetes, hypertension benefit from amlodipine/olmesartan medoxomil regimen
Tuesday, April 26, 2011

Approval for Meningitis Vaccine Expanded to Include Toddlers
As young as 9 months
Monday, April 25, 2011

Studies Add to Evidence on Clot Risk Tied to Contraceptives
Formulations with drospirenone linked to higher risk of clots than those with levonorgestrel
Friday, April 22, 2011

Intravaginal Probiotic May Lower UTIs in Premenopausal Women
High-level vaginal colonization with L. crispatus tied to drop in recurrence in treatment group
Thursday, April 21, 2011

Pioglitazone Not Tied to Most Cancers in Diabetes Patients
There may be a slightly higher risk for bladder cancer with long-term treatment
Thursday, April 21, 2011

Progesterone Gel Linked With Lower Rate of Preterm Birth
Gel reduces the frequency of preterm birth in women with sonographically short cervix lengths
Wednesday, April 20, 2011

Triple-Class Viral Failure Low in HIV-Infected Children
But children infected perinatally with HIV have higher triple-class viral failure rate than adults
Wednesday, April 20, 2011

New Test Effective for Detection of Tuberculosis
Test for Mycobacterium tuberculosis, rifampicin resistance shows high sensitivity and specificity
Tuesday, April 19, 2011

Most Parents Consider Children's Vaccines Important
Children's doctors are main but not sole trusted source for vaccine information
Monday, April 18, 2011

Adalimumab Maintains Remission of Childhood Uveitis
Compared with infliximab, adalimumab treatment more effective at delaying time to relapse
Monday, April 18, 2011

Anesthesia Complications Twice As Likely in Obese
Airway management events more likely to occur in the intensive care unit, emergency department
Thursday, April 14, 2011

More Than Half of U.S. Adults Take Dietary Supplements
Supplement intake has increased in the last 20 years, with more women taking supplements
Wednesday, April 13, 2011

AAN: Low Intensity Walking Improves Parkinson's Mobility
And the investigational drug safinamide appears to reduce dyskinesia in Parkinson's patients
Wednesday, April 13, 2011

Antibiotics for Acne May Not Up Prevalence of S. aureus
Long-term tetracycline use for acne may lower prevalence without increasing resistance
Wednesday, April 13, 2011

Alternative HPV Dosing Schedules Effective in Girls
Noninferiority criteria met in alternative dosing schedules within 12 months
Tuesday, April 12, 2011

Fixed-Dose Combos Equally Effective in TB Treatment
Drug combination does not demonstrate full noninferiority, but has potential advantages
Tuesday, April 12, 2011

Antenatal Paracetamol Use May Be Tied to Childhood Wheeze
More research needed to determine impact of prenatal paracetamol use on risk of asthma
Monday, April 11, 2011

'Global Trigger Tool' Identifies 10 Times More Errors
New tool identifies many more adverse events in hospital admissions compared to other methods
Thursday, April 07, 2011

Electronic Systems Reduce Drug Errors in Psychiatry
Computerized prescription and error reporting systems dramatically reduce most types of errors
Thursday, April 07, 2011

Guidelines for Juvenile Arthritis Treatment Published
Guidelines suggest drug therapies based on disease characteristics
Thursday, April 07, 2011

Self-Management of Anticoagulant Therapy Effective
Self-testing and adjustment of anticoagulant doses lower mortality and thromboembolic events
Thursday, April 07, 2011

New Yellow Fever Vaccine Safe and Effective
Vaccine containing inactivated antigen is promising alternative to live vaccine
Thursday, April 07, 2011

Maximum Daily Opioid Doses Increase Mortality Risk
But opioid overdose death risk is not affected by regular or as-needed dosing schedule
Tuesday, April 05, 2011

Alteration in Health Outcomes Post Estrogen Therapy
Reduced risk of breast cancer persists after cessation of conjugated equine estrogen therapy
Tuesday, April 05, 2011

ACC: Valsartan and Amlodipine Provide Similar Effects
And calcium channel blocker plus olmesartan benefits elderly patients with CVD
Tuesday, April 05, 2011

Little Support Found for Medication of Autism Symptoms
Behavioral and developmental interventions may be of some benefit
Monday, April 04, 2011

Breast Cancer Survival Factors for Underserved Identified
Limited awareness that breast cancer is treatable hinders survival in low-income countries
Monday, April 04, 2011

Medication, Communication Alleviate Latino Depression
Stigma related to antidepressant use and poor communication linked to persistence of depression
Friday, April 01, 2011

Autoimmune Diseases Number Two Cause of Chronic Illness
Major burden on all U.S. health care costs, patient expenses, and loss of earnings
Friday, April 01, 2011

Tetanus Cases Rare but Some Populations More Vulnerable
Older adults, injection drug users, people with diabetes more likely to be infected
Thursday, March 31, 2011

Growth Hormone Increases Adult Height in Turner's
Addition of low-dose estrogen may provide additional benefits
Thursday, March 31, 2011

Medical Abortion by Certified Nurses Safe and Effective
Nurses and auxiliary nurse midwives can safely administer abortions to women in remote areas
Thursday, March 31, 2011

FDA: Store Pradaxa Only in Original Containers
The anticoagulant is vulnerable to breakdown, loss of potency otherwise
Wednesday, March 30, 2011

Online Health Records Less Used by Minorities, Poor
Low-income patients, blacks, and Hispanics less likely to use Internet personal health record
Wednesday, March 30, 2011

Insulin Delivery System Recalled by Roche
Design flaw in ACCU-CHEK FlexLink Plus infusion sets may result in under-delivery of insulin
Tuesday, March 29, 2011

Four-Dose Rabies Prevention Vaccine Schedule Endorsed
American Academy of Pediatrics accepts new recommendations for postexposure vaccine
Tuesday, March 29, 2011

Complementary Treatment of Colic Lacks Evidence
Poor-quality evidence supporting colic treatment with complementary and alternative medicine
Monday, March 28, 2011

Citalopram, Finasteride Potentially Mislabeled
Recall issued because bottles of citalopram may contain finasteride
Monday, March 28, 2011

Use of Strategies to Reduce Risk of Opioid Misuse Is Low
At-risk patients are not monitored closely and are more likely to receive early opioid refills
Friday, March 25, 2011

Libido Unaffected by Endocrine Therapy in Breast Cancer
But chemotherapy-induced menopause reduces breast cancer patients' sexual desire
Friday, March 25, 2011

U.S. Shingles Vaccine Approval Expanded
To include people in their 50s
Thursday, March 24, 2011

Rheumatic Disease Patients Require Two Flu Vaccine Doses
Vaccine response independently affected by certain disease-modifying antirheumatic drugs
Wednesday, March 23, 2011

AAAAI: Regimen Desensitizes Youth With Milk Allergy
Omalizumab combined with oral desensitization improves tolerance with few side effects
Wednesday, March 23, 2011

Hydrocortisone Lowers Risk of Hospital-Acquired Pneumonia
Intravenous hydrocortisone lowers the risk of hospital-acquired pneumonia in trauma patients
Tuesday, March 22, 2011

Dalteparin Not Superior to Unfractionated Heparin
No difference in proximal DVT incidence in critically ill; but fewer pulmonary emboli
Tuesday, March 22, 2011

AAAAI: Combined OCPs Not Tied to Respiratory Issues
Progestin-estrogen oral contraceptives prior to pregnancy not tied to higher risk in offspring
Tuesday, March 22, 2011

Seven-Day On-Off Capecitabine Cycle Treats Breast Cancer
Modest efficacy and minimal toxicity for seven-day on-off capecitabine combined with bevacizumab
Tuesday, March 22, 2011

Atomoxetine of Limited Value in Young Children With ADHD
Drug reduces core ADHD symptoms but significant clinical and functional impairment persists
Tuesday, March 22, 2011

Combination Therapy Given to Elderly Without Indications
Renal dysfunction more likely in patients given ACE inhibitor and angiotensin-receptor blocker
Monday, March 21, 2011

Antibiotics Reduce Risk of ICU-Acquired Infection
Two preventive regimens reduce risk of infection with highly resistant microorganisms
Monday, March 21, 2011

Oral Vaccine May Prevent Half of Cholera Episodes
Cochrane review confirms vaccine's safety, suggests poorer efficacy in children under 5
Monday, March 21, 2011

Artesunate Provides Superior Treatment for Severe Malaria
More effective than standard quinine treatment for both children and adults
Friday, March 18, 2011

Bulking Agent Injections Effective in Fecal Incontinence
Dextranomer in stabilized hyaluronic acid injected into anal mucosa reduces fecal incontinence
Friday, March 18, 2011

Professional Values of U.S. and U.K. Doctors Examined
Nearly one-third of doctors fail to report inadequate colleague, often for fear of retribution
Thursday, March 17, 2011

17-Hydroxyprogesterone Does Not Lower Neonatal Morbidity
17-alpha-hydroxyprogesterone caproate does not prolong gestation in twin pregnancy
Thursday, March 17, 2011

Adding Omalizumab Improves Asthma Control in Youth
When drug added to guidelines-based therapy, reduces need for other medications
Wednesday, March 16, 2011

More Cholera Cases and Deaths Expected in Haiti
Clean water, vaccinations, better antibiotic distribution could reduce cholera cases and deaths
Wednesday, March 16, 2011

Drug-Related Poisonings Highest in Young Children
Poisonings with suicidal intent seen most often in young women
Monday, March 14, 2011

Risk of Infection, Malignancy With Anti-TNF Therapy Unclear
No raised risk in early rheumatoid arthritis patients, naive to methotrexate
Friday, March 11, 2011

Many Hepatitis C-Positive Patients Are Uninsured
Even lower proportion of patients who are eligible for treatment are covered by insurance
Friday, March 11, 2011

Automated Propofol and Remifentanil Delivery Effective
Closed-loop coadministration of propofol and remifentanil maintains Bispectral Index values
Friday, March 11, 2011

Depression Care in Hospital May Improve Cardiac Outcomes
Initiating depression intervention during admission improves medical outcomes six months later
Thursday, March 10, 2011

Insulin Degludec Effective Alternative to Insulin Glargine
May reduce dosing frequency from once daily to three times weekly
Thursday, March 10, 2011

HealthGrades Finds Rates of Patient Safety Events Vary
Patients have 46 percent lower risk of safety error in top versus bottom-ranking hospitals
Wednesday, March 09, 2011

Pharmacological Meta-Analyses Rarely Report Disclosures
Meta-analyses of pharmacological interventions rarely disclose funding or conflicts of interest
Tuesday, March 08, 2011

FDA: Adverse Events Tied to Kaletra in Preterm Infants
FDA revises label to include new warning outlining serious event risk in premature babies
Tuesday, March 08, 2011

Inhaled Epinephrine Gives Temporary Relief From Croup
Children's croup symptoms improve for up to two hours after treatment with epinephrine
Monday, March 07, 2011

FDA: Topiramate (Topamax) Tied to Risk of Oral Clefts
Higher risk of cleft lip and cleft palate in infants exposed to topiramate during first trimester
Friday, March 04, 2011

Ibuprofen Use Tied to Lower Risk of Parkinson's Disease
Use of other analgesics is not associated with risk of developing Parkinson's disease
Thursday, March 03, 2011

Injectable Risperidone No Better Than Oral Antipsychotics
Does not reduce hospitalization rates or improve other outcomes in schizophrenia patients
Thursday, March 03, 2011

Cannabis Use in Youth Ups Incident Psychosis Risk
Study also finds that continued cannabis use may increase risk of persistent psychotic symptoms
Thursday, March 03, 2011

Diuretic Has Similar Effect Regardless of Method or Dose
Acute decompensated heart failure patients respond about the same
Thursday, March 03, 2011

Intensive Glucose Therapy May Not Be Best in Type 2 Diabetes
Such therapy in those at increased cardiovascular risk related to higher risk of mortality
Wednesday, March 02, 2011

Maternal Opioid Use Tied to Higher Birth Defect Risk
Opioid analgesic use just prior to or during early pregnancy may up risk of certain defects
Wednesday, March 02, 2011

FDA: Proton Pump Inhibitors Tied to Hypomagnesemia
Low serum magnesium levels may occur when the drugs are taken for prolonged periods of time
Wednesday, March 02, 2011

FDA Cracking Down on Unapproved Prescription Drugs
Agency to remove unapproved cough, cold, and allergy medications from U.S. market
Wednesday, March 02, 2011

Increased Dietary Potassium Tied to Lower Stroke Risk
Dietary potassium may also help reduce risk of heart disease and total cardiovascular disease
Wednesday, March 02, 2011

Risk of Adverse Effects Lessens Drug Acceptance in Elderly
Elderly likely to accept drugs with only mild benefits, but less so with adverse effect risk
Wednesday, March 02, 2011

Inhaled Nitric Oxide Does Not Shorten Sickle Cell Crisis
Inhaled nitric oxide gas does not reduce the duration of vaso-occlusive pain crisis
Wednesday, March 02, 2011

Antihypertensives Beneficial in Absence of Hypertension
In patients with cardiovascular disease, antihypertension drugs tied to lower morbidity
Tuesday, March 01, 2011

U.S. Breast Cancer Incidence Rates Stabilized After 2003
Rates stopped declining after sharp drop that coincided with decrease in hormone therapy use
Tuesday, March 01, 2011

Opioid Treatment Associated With Cognitive Dysfunction
Possible or definite cognitive dysfunction seen in one-third of opioid-treated cancer patients
Tuesday, March 01, 2011

Many Patients Do Not Consolidate Drugs Efficiently
Low literacy identified as independent predictor of dosing more times than necessary per day
Tuesday, March 01, 2011

Edarbi Approved for Treatment of Hypertension
But shouldn't be taken by pregnant women
Monday, February 28, 2011

Tranexamic Acid Lowers Post-Op Blood Loss in Neck Surgery
Reduced perioperative bleeding following cervical laminoplasty limits total surgery blood loss
Monday, February 28, 2011

Bupropion Improves Sexual Function in Type 2 Diabetes
Mean sexual energy scale scores improve in some patients with hyperglycemia or depression
Wednesday, February 23, 2011

Herpes Zoster Risk Tied to COPD
Risk of herpes zoster also increases with the use of steroids, particularly oral corticosteroids
Wednesday, February 23, 2011

Nitroglycerin Strengthens Bones in Older Women
Treatment found to increase bone mineral density, lower bone resorption in postmenopausal women
Wednesday, February 23, 2011

Aspirin May Lower Type 2 Diabetes Atherosclerosis Risk
Low-dose aspirin may benefit patients with type 2 diabetes and mild renal dysfunction
Tuesday, February 22, 2011

FDA Issues Label Changes for Antipsychotic Drug Class
Labels outline the risk to newborns whose mothers took the drug in third trimester
Tuesday, February 22, 2011

Children With Hepatitis C May Benefit From Ribavirin
Improved response for children treated with combination of pegylated interferon and ribavirin
Tuesday, February 22, 2011

Warfarin Lot Being Recalled Due to Mislabeled Bottle
One bottle was labeled as 3 mg tablets but contained 10 mg tablets
Friday, February 18, 2011

FDA Warns Against Terbutaline for Preterm Labor
Prolonged use can be life-threatening to pregnant women
Thursday, February 17, 2011

Oral Bisphosphonates May Lower Colorectal Cancer Risk
Use of bisphosphonates tied to reduced cancer risk in postmenopausal women
Thursday, February 17, 2011

Analgesic Efficacy Altered by Patient Beliefs
Subjective pain relief and pain-related brain activity affected by patient expectations
Thursday, February 17, 2011

New U.S. Report on the Nation's Health 2010 Released
The 34th annual CDC report includes a special feature on death and dying
Wednesday, February 16, 2011

Zinc May Reduce Duration and Severity of Common Cold
Prophylactic treatment reduces cold incidence, school absence, and antibiotic prescriptions
Wednesday, February 16, 2011

Increased Errors With Liquid Medications and Inhalers
Fewer errors with medications drawn from monitored dosage systems
Wednesday, February 16, 2011

Most Recalled Medical Devices Given Lenient Approval
Over 70 percent of the medical devices recalled were considered low or moderate risk
Tuesday, February 15, 2011

Corticosteroid Effective Asthma Rescue Addition
Albuterol, corticosteroids more effective rescue treatment than albuterol for mild childhood asthma
Tuesday, February 15, 2011

New Drug Offers Alternative to Warfarin
Dabigatran effective in prevention of blood clots for patients with atrial fibrillation
Monday, February 14, 2011

Researchers Explore Nature of Difficult Clinical Encounters
Patients, physicians both contribute characteristics; difficult patients have worse outcomes
Monday, February 14, 2011

Different Black Box Warnings Common in Same-Class Drugs
Differences in safety warning labels identified in nine of 20 top-selling drug classes
Monday, February 14, 2011

Undefined Liver Failure Linked to Acetaminophen
Acetaminophen toxicity may be responsible for some cases of unspecified liver failure
Monday, February 14, 2011

ASA: Acute Stroke Patients May Not Benefit From Candesartan
Drug not effective in patients with acute stroke and hypertension and may even be harmful
Friday, February 11, 2011

ASA: Most Don't Receive Timely Dose of Clot-Busting Drug
Tissue plasminogen activator usually not given within 60 minutes despite improved survival
Friday, February 11, 2011

Low-Molecular-Weight Heparin May Not Prevent Thrombosis
Low-dose heparin in women at high risk of pregnancy-related VTE leads to treatment failure
Thursday, February 10, 2011

SMFM: Folate Not Protective Against Preterm Delivery
Folate supplements before or during pregnancy not tied to spontaneous preterm birth
Thursday, February 10, 2011

Public Sector Plays Big Role in Drug Research
Role of public-sector research institutions larger than previously thought
Wednesday, February 09, 2011

Errors in Hospital Analgesia Prescriptions Nearly 3 in 1,000
Prescription error rate more than double in pediatric population
Wednesday, February 09, 2011

Earlier Onset of Psychosis Linked to Cannabis Use
Age of onset nearly three years younger for cannabis users than nonusers
Wednesday, February 09, 2011

Drug Approved to Help Prevent Preterm Birth
Makena for women at risk of delivering early
Friday, February 04, 2011

Single Dose of H1N1 Vaccine Highly Effective in Young
Study finds adjusted effectiveness was 93 percent overall in Canada in 2009
Friday, February 04, 2011

Among Statin Users, Smoking Cessation Deserves Emphasis
More intense statin therapy does not appear to mitigate cardiovascular risk from smoking
Thursday, February 03, 2011

Givinostat a Promising Treatment for Juvenile Arthritis
Drug appears safe, well tolerated, beneficial for arthritic component of disease
Thursday, February 03, 2011

Timing of Hormone Therapy Influences Breast Cancer Risk
Starting hormone therapy soon after menopause is associated with increased risk of breast cancer
Thursday, February 03, 2011

H1N1 Vaccine Appears Safe
Surveillance identifies few serious adverse events, no increased risk of Guillain-Barré
Wednesday, February 02, 2011

Vaccine Prevents Human Papillomavirus in Males
Vaccination efficacious against genital lesions and genital human papillomavirus infection
Wednesday, February 02, 2011

Few Older Adults Receive Herpes Zoster Vaccination
Only 6.7 percent of adults aged 60 and older were vaccinated by 2008
Thursday, January 27, 2011

Trospium Treatment Effective for Overactive Bladder
Men with overactive bladder benefit from trospium treatment with low risk of urinary retention
Thursday, January 27, 2011

Electronic Health Records May Not Improve Care Quality
Use with clinical decision support not tied to better quality of care
Wednesday, January 26, 2011

Antioxidant Supplementation May Improve Male Fertility
Increase in live births and pregnancy rate with use of antioxidants by the male partner
Wednesday, January 26, 2011

Allegra Approved for Over-the-Counter Sale
Beginning in March
Tuesday, January 25, 2011

Substantial Source of Dosing Error Found for Pediatric Patients
Accurate preparation of small-volume medication doses for pediatric patients may be problematic
Monday, January 24, 2011

Pharmacist Involvement Improves Disease Management
Pharmacists help patients with type 2 diabetes manage hypertension
Monday, January 24, 2011

Bisphosphonates May Improve Survival in Duchenne MD
With steroids, result in better survival than steroids alone for Duchenne muscular dystrophy
Wednesday, January 19, 2011

Malaria Vaccine Offers Children Long-Lasting Protection
Young African children may be protected from malaria for at least 15 months after vaccination
Wednesday, January 19, 2011

Low Medication Adherence After Myocardial Infarction
Medication adherence after myocardial infarction low in elderly patients with kidney dysfunction
Friday, January 14, 2011

CDC Report Highlights Important Health Disparities
Outlines disparities by sex, race/ethnicity, income, and other social characteristics
Thursday, January 13, 2011

FDA Limits Acetaminophen in Combo Prescription Products
Sets 325 mg maximum in order to lower risk of liver toxicity; also requesting boxed warning
Thursday, January 13, 2011

Anti-Epileptic Drugs Increase Risk of Fractures
Hypertension medications may provide potential osteoprotective benefits
Thursday, January 13, 2011

Combination Therapy Bests Monotherapy for BP Control
Patients experience greater blood pressure drop with aliskiren, amoldipine taken together initially
Thursday, January 13, 2011

Antibiotics Benefit Acute Ear Infections in Young Children
Otitis media symptoms are reduced more quickly with amoxicillin-clavulanate compared with placebo
Wednesday, January 12, 2011

Splitting Tablets Can Result in Dose Deviations
Use of a splitting device reduces the weight deviation and weight loss of the resulting tablet parts
Wednesday, January 12, 2011

Vaccine Reduces Risk of Herpes Zoster
In immunocompetent adults over age 60, herpes vaccine protects from herpes zoster
Tuesday, January 11, 2011

Aspirin Use in High-Risk Individuals Is Suboptimal
And whites are more likely than other races to adhere to aspirin regimen
Tuesday, January 11, 2011

FDA Warns of Morphine Sulfate Oral Solution Overdose
100 mg per 5 mL product ordered in mg may be mistakenly interchanged for mL of the product
Tuesday, January 11, 2011

Corticosteroid Use May Shorten Children's Hospital Stays
Readmission rates higher in children not receiving both corticosteroids and β-agonists
Tuesday, January 11, 2011

Burnout Levels Particularly High in Residents
High percentage of anesthesiology chairs also meet criteria for high or moderately-high burnout
Monday, January 10, 2011

Fluoxetine May Improve Post-Stroke Motor Function
The antidepressant shows promise as stroke treatment in those with motor impairments
Monday, January 10, 2011

Bright Light Treatment Improves Nonseasonal Depressive Disorder
But donepezil added to pharmacotherapy may not prevent progression of cognitive impairment
Thursday, January 06, 2011

Severe Skin Lesions Can Cause IBD Patients to Quit Therapy
If topical treatment fails, lesions caused by anti-tumor necrosis factor may cause discontinuation
Wednesday, January 05, 2011

Pediatric Acute Sinusitis Visit Rates Unchanged
Visits stable after vaccine introduction, but amoxicillin use increased in line with guidelines
Thursday, December 30, 2010

Different Opioids Linked to Different Risks of Events
Subjects were Medicare beneficiaries prescribed five common opioids for nonmalignant pain
Wednesday, December 15, 2010

Intervention Addresses Opioid Delivery in Pediatric Fractures
Authors discuss process that leads to faster treatment in children with extremity fractures
Tuesday, December 14, 2010

In Pregnancy, Buprenorphine Effective for Opioid Dependency
Alternative to methadone; tied to reduced treatment for neonatal abstinence syndrome
Wednesday, December 08, 2010

Nausea, Vomiting in Pregnancy Decrease With Diclectin
Delayed-release formulation may improve quality of life during pregnancy
Wednesday, December 08, 2010

Reimbursement Issues Hinder Combination Vaccine Uptake
Practice size, patient insurance status play a role for pediatricians too
Monday, December 06, 2010

ASH: Oral Venous Thrombosis Agent Effective and Safe
Rivaroxaban may provide a simple, fixed-dose approach for short-term and continued treatment
Monday, December 06, 2010

Spina Bifida Is Only Major Risk to Fetus From Carbamazepine