Clinical Update: Psoriasis

Psoriasis is a chronic, inflammatory autoimmune skin disease. In psoriasis, an overproduction of CD4 helper T cells leads to rapid keratinocyte proliferation. Skin cells pile up on the surface and the characteristic psoriatic lesions, or plaques, result. These plaques are generally red and circular, with a patchy appearance, and covered with thick silver scales. They are often itchy and can be painful. A diagnosis of psoriasis is made based on patient history, appearance of lesions, and microscopic evaluation of the plaque cells.

Treatments for psoriasis are targeted toward reducing symptoms and improving quality of life. Keratolytic medications, corticosteroids, emollients, shampoos, lotions, coal tar preparations, Vitamin A derivatives, antihistamines, baths with colloidal oatmeal products, moisturizers, systemic corticosteroids and other immunosuppressants, and disease-modifying antirheumatic drugs (DMARDs) are among the list of available psoriasis treatments. Ultraviolet phototherapy is often an effective nonpharmacologic treatment for psoriasis. Patients with severe psoriasis who develop psoriatic arthritis may also benefit from physical therapy and rehabilitation; joint replacement therapy may be indicated in some cases.
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This Just In

From Our Journals

 Mechanistic Insights Into Today’s (and Tomorrow’s) Treatments for Moderate-to-Severe Psoriasis
Journal of the Dermatology Nurses' Association, February 2016

 Providing Guidance for Patients With Moderate-to-Severe Psoriasis Who Are Candidates for Biologic Therapy: Role of the Nurse Practitioner and Physician Assistant
Journal of the Dermatology Nurses' Association, February 2016

 Psoriasis
Journal of the Dermatology Nurses' Association, May/June 2015

 Management of patients with psoriatic arthritis
The Nurse Practitioner, April 2015 

 Psoriasis: An overview and update
The Nurse Practitioner, March 2015 

 Knowledge Is (P)so Powerful
Journal of the Dermatology Nurses' Association, November/October 2014

 Measuring Psoriasis Severity: Why Does it Matter?
Journal of the Dermatology Nurses' Association, September/October 2014

 Resources for Psoriasis
Nursing2014, September 2014

 Biologic Agents for Moderate-to-Severe Plaque Psoriasis: Mechanisms of Action and Treatment Considerations 
Journal of the Dermatology Nurses' Association, July/August 2014

 Research Evidence for Reducing Cardiovascular Risk With Biologic Therapies in Patients Who Have Psoriasis
Journal of the Dermatology Nurses' Association, May/June 2014
 

 Psoriasis Comprehensive Care: An Evaluation of a Web Site
CIN: Computers, Informatics, Nursing, January 2014


 A Review of the Clinical Variants and the Management of Psoriasis
Advances in Skin & Wound Care: The Journal for Prevention and Healing, June 2013


 Making a Difference: Nurse Prescribing for Patients With Psoriasis in the United Kingdom
Journal of the Dermatology Nurses' Association, May/June 2013

 Guest Editorial: Virtual Psoriasis Symposium: A Unique Educational Format for Dermatology and Primary Care Nurses and Nurse Practitioners
Journal of the Dermatology Nurses' Association, January 2013

 Wound Wise: The skinny on psoriasis
Nursing Made Incredibly Easy!, September/October 2010

 The Psychological Impact of Psoriasis: A Review of Short-term Psychotherapy Group Participation for Psoriasis Patients
Journal of the Dermatology Nurses' Association, July/August 2010

 Patch Testing Patients With Worsening Psoriasis Vulgaris
Journal of the Dermatology Nurses' Association, November/December 2009

 Diagnosis and Management of Psoriatic Arthritis: A Practical Review
Journal of the Dermatology Nurses' Association, September/October 2009 

 Defining Inadequate Response to Biologic Psoriasis Treatments: Considering Alternative Biologic Therapy
Journal of the Dermatology Nurses' Association, January/February 2009

 

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