Let us help you stay updated about H1N1 influenza. Review key facts, stay in-the-know about WHO alerts, get the latest drug recommendations for treatment and prophylaxis, and more.


Lisa Bonsall, MSN, RN, CRNP
NursingCenter.com's Clinical Editor
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Key Facts about H1N1
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- H1N1 is a respiratory illness caused by type A influenza viruses.
- Transmission may occur in similar ways that other flu viruses spread, such as through coughing or sneezing, or touching something with the
virus on it and then touching one's mouth or nose.
- A person cannot get this new HIN1 virus from eating pork or pork products.
- Symptoms of H1N1 include fever, cough, sore throat, runny or stuffy nose, body aches, headache, chills, fatigue, diarrhea, and
vomiting.
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The Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) recommends that the following
groups be vaccinated against H1N1 influenza:
- pregnant women
- people who live with or care for children less than 6 months old
- health care and emergency services personnel
- people between the ages of 6 months through 24 years of age
- people ages 25 through 64 years who are at higher risk for novel H1N1 because of chronic health disorders or compromised immune
systems
In the event of a vaccine shortage, the ACIP recommends that the following groups receive the vaccine before others:
- pregnant women
- people who live with or care for children less than 6 months of age
- health care and emergency services personnel with direct patient contact
- children between 6 months and 4 years of age
- children ages 5 through 18 years of age who have chronic medical conditions
To decrease the incidence of secondary pneumococcal pneumonia, the CDC is also recommending prophylactic administration of 23-valent pneumococcal polysaccharide vaccine (PPSV23) during the outbreak of novel
influenza A(H1N1). The recommendations of the CDC's Advisory Committee on Immunization Practices (ACIP) are as follows:
- Vaccination for all persons over 65 years of age
- Vaccination for persons 2 to 64 years with the following medical conditions:
- Chronic cardiovascular disease (congestive heart failure and cardiomyopathies)
- Chronic pulmonary disease, including COPD and emphysema
- Diabetes mellitus
- Alcoholism
- Chronic liver disease, including cirrhosis
- Cerebrospinal fluid leaks
- Functional or anatomical asplenia, including sickle cell disease and splenectomy
- Immunocompromised conditions, including HIV infection, leukemia, lymphoma, Hodgkin's disease, multiple myeloma, generalized malignancy,
chronic renal failure, nephrotic syndrome; those receiving immunosuppressive chemotherapy (including corticosteroids); and those who have received an organ or bone
marrow transplant
- Vaccinations for persons 19 to 64 years who have asthma or smoke.
*Note: A single revaccination at least five years after initial vaccination is recommended for people 65 years and older who were first
vaccinated before age 65 years as well as for people at highest risk, such as those who have no spleen, and those who have HIV infection, AIDS or
malignancy.
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The CDC has outlined specific antiviral guidelines for
prevention and treatment of confirmed, probable, and suspected cases of patients with H1N1 influenza and their close contacts.
Current antiviral dosing recommendations are as follows:
oseltamivir (Tamiflu)
To prevent H1N1 influenza. Adults: 75 mg capsule by mouth (P.O.) once daily for 10 days Children 12 months and older weighing greater than 40 kg: 75 mg P.O. once daily for 10 days Children 12 months and older weighing 23 kg to 40
kg: 60 mg P.O. once daily for 10 days Children 12 months and older weighing 15 kg to 23 kg: 45 mg P.O. once daily for 10 days Children 12
months and older weighing 15 kg or less: 30 mg P.O. once daily for 10 days Infants 6 to 11 months: 25 mg P.O. once daily for 10 days Infants
3 to 5 months: 20 mg P.O. once daily for 10 daysInfants less than 3 months: Not recommended unless situation judged critical due to limited data in
use in this age group.
To treat H1N1 influenza. Adults: 75 mg capsule P.O. twice daily for 5 days Children 12
months and older weighing greater than 40 kg: 75 mg P.O. twice daily for 5 days Children 12 months and older weighing 23 kg to 40 kg: 60 mg P.O.
twice daily for 5 days Children 12 months and older weighing 15 kg to 23 kg: 45 mg P.O. twice daily for 5 days Children 12 months and older
weighing 15 kg or less: 30 mg P.O. twice daily for 5 days Infants 6 to 11 months: 25 mg P.O. twice daily for 5 days Infants 3 to 5
months: 20 mg P.O. twice daily for 5 daysInfants less than 3 months: 12 mg P.O. twice daily for 5 days
Click here for complete prescribing
information for oseltamivir (Tamiflu).
zanamivir (Relenza)
To prevent H1N1 influenza. Adults: Two 5 mg inhalations (10 mg total) once daily for 10 days Children 5 years and older: Two 5 mg inhalations (10 mg total) once daily for 10 days To treat H1N1 influenza. Adults: Two 5 mg inhalations (10 mg total) twice daily for 5 days Children 7 years and older:
Two 5 mg inhalations (10 mg total) twice daily for 5 days
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You may be hearing a lot about H1N1, not only through the media, but also from the patients that you are seeing in your practice. Login to access our new printable patient education guide to educate yourself and your patients about influenza A(H1N1).
This tool is available to you in English and Spanish, courtesy of Lippincott's NursingCenter.com and Anatomical Chart Company. Not yet a member of Lippincott's NursingCenter.com? Join now!
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WHO Levels of Pandemic
Alert |
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Since June of 2009, the World Health Organization has maintained the
worldwide pandemic alert level at Phase 6. What does this mean?
The WHO uses a 6-phased approach to describe pandemics. Phases 1-3 have to do with preparedness, while phases 4-6 focus on the need for
response. Let's break this down even further:
Phase 1: no viruses circulating among animals have been reported to cause infections in humans Phase
2: a circulating animal influenza virus is known to have caused infection in humans Phase 3: an animal or human-animal influenza virus has caused
sporadic cases or small clusters of disease in people; limited human-to-human transmission may occur Phase 4: verified human-to-human
transmission of an animal or human-animal influenza virus able to cause “community-level outbreaks.” This marks a significant upwards shift in the risk
for a pandemic. Phase 5: characterized by human-to-human spread of the virus into at least two countries in one WHO region; strong signal that a
pandemic is imminent Phase 6*: community level outbreaks in at least one other country in a different WHO
region in addition to the criteria defined in Phase 5; a global pandemic is under way. *Currently at this level
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PHARMACOLOGY CONSULT: Bird Flu, Swine Flu, and Resistant Influenza: The Scary Development of Antiviral-Resistant Strains-Part 1: Update for the Clinical Nurse Specialist Clinical Nurse Specialist: The Journal for Advanced Nursing Practice
Pharmacology Consult: Bird Flu, Swine Flu, and Resistant Influenza: The Scary Development of Antiviral-Resistant Strains-Part 2 Novel A(H1N1): The Flu We Never Expected Clinical Nurse Specialist: The Journal for Advanced Nursing Practice
Be prepared for H1N1 flu Nursing Made Incredibly Easy
CDC Guidance for Nurses on the Swine Flu AJN, American Journal of Nursing
Questions and Answers on Pandemic Influenza AJN, American Journal of Nursing
‘Diligent High School Nurse’ Instrumental in Discovery of Swine Flu Outbreak AJN, American Journal of Nursing
Prepared or Unprepared for Pandemic Flu? Journal of Christian Nursing
Using Nonpharmaceutical Interventions to Prevent Influenza Transmission in Elementary School Children: Parent and Teacher Perspectives Journal of Public Health Management & Practice
Global Infections: Recognition, Management, and Prevention The Nurse Practitioner: The American Journal of Primary Health Care
EMERGING INFECTIONS: Influenza A (H1N1): A Wake-Up Call AJN, American Journal of Nursing
Influenza Classics from the AJN Archives AJN, American Journal of Nursing
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Centers for Disease Control and Prevention (CDC)
World Health Organization (WHO)
Food and Drug Administration (FDA)
Flu.gov
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