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  1. Aschenbrenner, Diane S. MS, APRN-BC


* Potentially dangerous electrocardiographic changes may occur when the HIV protease inhibitors saquinavir (Invirase) and ritonavir (Norvir) are taken together.


* Either a prolonged QT interval, which can lead to torsades de pointes, or a prolonged PR interval, which can lead to heart block, can occur.