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HAART, HIV/AIDS, IRIS, Opportunistic infections



  1. Carr, Rebecca Lamb PhD, RN, ACNS-BC
  2. Traufler, Robin MN, RN-CS, ACNP


Immune reconstitution inflammatory syndrome is a constellation of clinical manifestations seen in patients with HIV/AIDS who are taking highly active antiretroviral therapy. The revitalization of their immune systems by these medications leads to the emergence of opportunistic infections that had been treated previously and those never treated. Some of these diseases have serious ramifications if undetected. To care for these patients, the critical-care nurse must be aware of their presentation and treatment.