Authors

  1. Blasco, Ana PhD
  2. Carmona, Montserrat MD
  3. Fernandez-Lozano, Ignacio PhD
  4. Salvador, Carlos H. PhD
  5. Pascual, Mario PhD
  6. Sagredo, Pilar G. MD
  7. Somolinos, Roberto BmE
  8. Munoz, Adolfo PhD
  9. Garcia-Lopez, Fernando PhD
  10. Escudier, Juan M. MD
  11. Mingo, Susana PhD
  12. Toquero, Jorge PhD
  13. Monivas, Vanessa MD
  14. Gonzalez, Miguel A. MEng
  15. Fragua, Juan A. MEng
  16. Lopez-Rodriguez, Fernando BS
  17. Monteagudo, Jose L. PhD
  18. Alonso-Pulpon, Luis PhD

Abstract

PURPOSE: Efficient ways are needed to implement the secondary prevention (SP) of coronary heart disease. Because few studies have investigated Web-based SP programs, our aim was to determine the usefulness of a new Web-based telemonitoring system, connecting patients provided with self-measurement devices and care managers via mobile phone text messages, as a tool for SP.

 

METHODS: A single-blind, randomized controlled, clinical trial of 203 acute coronary syndrome (ACS) survivors, was conducted at a hospital in Madrid, Spain. All patients received lifestyle counseling and usual-care treatment. Patients in the telemonitoring group (TMG) sent, through mobile phones, weight, heart rate, and blood pressure (BP) weekly, and capillary plasma lipid profile and glucose monthly. A cardiologist accessed these data through a Web interface and sent recommendations via short message service. Main outcome measures were BP, body mass index (BMI), smoking status, low-density lipoprotein-cholesterol (LDL-c), and glycated hemoglobin A1c (HbA1c).

 

RESULTS: At 12-month followup, TMG patients were more likely (RR = 1.4; 95% CI = 1.1-1.7) to experience improvement in cardiovascular risk factors profile than control patients (69.6% vs 50.5%, P = .010). More TMG patients achieved treatment goals for BP (62.1% vs 42.9%, P = .012) and HbA1c (86.4% vs 54.2%, P = .018), with no differences in smoking cessation or LDL-c. Body mass index was significantly lower in TMG (-0.77 kg/m2 vs +0.29 kg/m2, P = .005).

 

CONCLUSIONS: A telemonitoring program, via mobile phone messages, appears to be useful for improving the risk profile in ACS survivors and can be an effective tool for secondary prevention, especially for overweight patients.