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  1. Aschenbrenner, Diane S. MS, RN


* Elotuzumab (Empliciti) is a new monoclonal antibody approved to treat multiple myeloma in combination with lenalidomide (Revlimid) and dexamethasone.


* Use is restricted to patients who have already received one to three drug therapies to treat the condition.


* Elotuzumab commonly produces infusion reactions, and premedication is necessary. Patients may also develop second primary malignancies or hepatotoxicity. Response to the drug can be difficult to measure.