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  1. Aschenbrenner, Diane S. MS, RN


* Nivolumab (Opdivo) is now approved to treat advanced renal cell cancer in patients who have already received antiangiogenic therapy.


* The drug has the potential to cause serious immune-mediated effects, such as pneumonitis, colitis, hepatitis, endocrinopathies, nephritis and renal dysfunction, rash, and encephalitis.