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In October, the American Society of Clinical Oncology published new guidelines for women at risk for cervical cancer, stratified by resource setting. The key recommendations aim to improve care for women with variable access to prevention and treatment. While resource limits are acknowledged, the authors emphasize that clinical practice should aim for the highest level of care available and complement, rather than replace, local guidelines. Screening frequency recommendations for human papillomavirus DNA testing vary from every five years in women 25 to 65 years in maximal resource settings to every 10 years in women 30 to 49 years in limited resource settings