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  1. Matsui, Yuko PhD, RN
  2. Murayama, Ryoko PhD, RN
  3. Tanabe, Hidenori ME
  4. Oe, Makoto PhD, RN
  5. Motoo, Yoshiharu MD, PhD
  6. Wagatsuma, Takanori MSN, RN, CNS
  7. Michibuchi, Michiko RN
  8. Kinoshita, Sachiko MSN, RN, WOCN
  9. Sakai, Keiko PhD, RN
  10. Konya, Chizuko PhD, RN, WOCN
  11. Sugama, Junko PhD, RN
  12. Sanada, Hiromi PhD, RN


Early detection of extravasation is important, but conventional methods of detection lack objectivity and reliability. This study evaluated the predictive validity of thermography for identifying extravasation during intravenous antineoplastic therapy. Of 257 patients who received chemotherapy through peripheral veins, extravasation was identified in 26. Thermography was performed every 15 to 30 minutes during the infusions. Sensitivity, specificity, positive predictive value, and negative predictive value using thermography were 84.6%, 94.8%, 64.7%, and 98.2%, respectively. This study showed that thermography offers an accurate prediction of extravasation.