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Capsules less objectionable than colonoscopy for those receiving fecal transplantation. One non-odorous oral capsule made from a healthy donor's feces was 96% effective in preventing recurrences of Clostridium difficile infection (CDI) over 12 weeks in people with recurrent CDI, according to an article in the November 28, 2017, JAMA. The capsule was as successful as fecal transplantation via colonoscopy. Two-thirds of people taking the capsules rated their experience as "not at all unpleasant," compared with 44% of the colonoscopy group. Capsules are taken in an office and cost $308, compared with $874 for colonoscopy. Broader questions remain, including when to give fecal capsules; the role of other fecal components, such as bile acids and bacteriophages; and the timing of vancomycin treatment.