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Pediatric burn treatment, SJS, Stevens-Johnson syndrome, TEN, toxic epidermal necrolysis



  1. Wedel, Lisa MS, APRN, CPNP-PC
  2. Rash, Diane MSN, APRN, CPNP-PC, AC


Abstract: Toxic epidermal necrolysis is a rare, life-threatening, drug-induced disease that was first described by a Scottish dermatologist named Dr. Alan Lyell in 1958. After nearly 60 years, the mortality rate remains at approximately 30%. Stevens-Johnson syndrome and toxic epidermal necrolysis are differentiated by the percentage of skin involvement, with greater than 30% being classified as toxic epidermal necrolysis. Patients with Stevens-Johnson syndrome and toxic epidermal necrolysis should be managed in a burn or intensive care unit. Prompt identification is crucial to the effective management and treatment of the disease. This article presents a case study of a 10-year-old boy diagnosed with toxic epidermal necrolysis with 94% skin involvement who was effectively treated and discharged without major complications or infections.