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  1. Poole, Susan K. BSN, MS, CRNI(R), CNSN
  2. Nowobilski-Vasilios, Anna PharmD, MBA, BCNSP, FASHP


Colony-stimulating factors are potent manipulators of the hematopoietic and immune systems. An increasing number of colony-stimulating factors with expanded indications and uses are available. To provide safe and efficacious therapy, clinicians must understand how colony-stimulating factors and other biologic response modifiers work and know about product use, patient education, and patient monitoring. This article provides an overview of the current colony-stimulating factor products, uses, indications, administration, management, and patient education.