Objectives: (1) To discuss the impact of attrition on research and considerations in select populations, (2) to present strategies aimed at minimizing attrition based on the literature, and (3) to present results of the TBI model systems. Methods: Current literature on attrition was reviewed and comprehensive strategies were outlined. Results: Attrition impact and risk factors are outlined. Researchers should consider contact information, project name/logo, tollfree line; intensive initial efforts, staff awareness, data-collection times/methods, and frequent mailings, defining a specific follow-up protocol. Participants are more likely to continue when there is rapport, understanding, convenience, feedback, incentive, and motivation. Conclusions: Attrition carries a high cost for research and may lead to misinterpretations during data analysis. Researchers must develop a comprehensive plan to minimize this loss.
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